Houston microgrid tech company announces $150 investment

hauling in cash

Houston-based VoltaGrid provides small-scale, self-contained microgrids that can operate independently of major power grids or in tandem with other microgrids. Photo via voltagrid.com

VoltaGrid, a Bellaire-based startup that specializes in distributed power generation via microgrids, has hauled in $150 million in equity funding.

Founded in 2020, VoltaGrid provides small-scale, self-contained microgrids that can operate independently of major power grids or in tandem with other microgrids. VoltaGrid’s product consists of natural gas engines, portable energy storage, natural gas processing and grid power connectivity.

Investors in the $150 million round include the Canada Pension Plan Investment Board (CPP Investments), Longbow Capital, Walter Ventures, and Pilot Company (operator of more than 800 retail and fueling locations in the U.S. and Canada). The $150 million round comes less than a year after VoltaGrid announced a $100 million round featuring the same investors.

VoltaGrid says it will spend the fresh cash to grow its power generation portfolio, along with its low-carbon fuel program in partnership with Pilot. The low-carbon platform features hydrogen and compressed natural gas.

“VoltaGrid continues to set new milestones across multiple sectors and business lines as we execute on our proven strategy with key partners,” Nathan Ough, president and CEO of VoltaGrid, says in a news release.

“Our strategy to establish one of the largest asset bases of portable generation, uniquely paired with our low-carbon fueling solutions, has significantly decreased the complexity for our partners to electrify their operations. I am thankful to our team members for the tremendous amount of work that has been contributed to create one of the largest portfolios of contracted low carbon fuels in the industry.”

Ed Pettitt and Paresh Patel join the Houston Innovators Podcast to discuss InnoGrid's potential impact on equitable power. Photos courtesy of InnoGrid

Houston founders aim to provide equity through energy resiliency

Houston innovators podcast episode 143

As temperatures climb and devastating natural disasters continue to test the power grid, two Houston innovators have a solution: Smart microgrids.

"Microgrids have been around for a very long time," Paresh Patel, co-founder of InnoGrid, says on the Houston Innovators Podcast. "We're primed here in Houston and in Texas to really see microgrids go mainstream. ... People want to see that they have control and are in charge of their own power."

Patel co-founded InnoGrid with Ed Pettitt and a few other collaborators following the 2020 Houston Climathon. The social enterprise is working to establish community microgrids in lower income areas — neighborhoods that are most at risk of devastating power outages.

"We want to convert the commercial microgrid model for low and moderate income and undresourced residential communities," Patel explains.

And there's never been a better time to shine a spotlight on microgrids as a solution to unreliable power systems, Pettitt says.

"We're dealing with massive inflation — costs are going up especially in food and energy," he explains on the show. "Even prior to this time of inflation, electricity prices in the US were expected to increase across the board. Hundreds of thousands of people right now today are being pushed below the poverty line because of increased energy costs. We need to be more creative in how we upgrade our infrastructure."

And the current grid system is well overdue for an upgrade. The microgrid system fits right in with the shared economy we live in today, Patel says, and it allows for more generation of energy that is decentralized, digitalized, decarbonized, and democratized — the four Ds as he says.

"When you consider our current grid system, it is a vestige of the industrial revolution — it's 140 years old. That business model is ripe for innovation," Patel says.

"We need to accelerate deployment of microgrid models," he continues. "I don't think we can afford to update our current grid system — it'll cost $2 trillion."

Most importantly, these microgrids need to be implemented in an equitable way, the founders say, and InnoGrid has its eyes on one Houston area in particular. The Innovation Corridor, which spans from the Texas Medical Center to Downtown Houston, would be the ideal region to deploy the technology.

"If you look at the innovation corridor, it forms the spine of the city. You have so many important municipal buildings, first-responding organizations, and a large amount of affordable housing in the area. There's critical resources here that we want to make sure the lights stay on in power disasters," Pettit says. "One of the things we believe at InnoGrid is that where you live shouldn't determine whether or not you survive a national weather event. We want to make sure we provide energy stability in the communities that need it most."

To make this dream into a reality, InnoGrid needs the right partnerships and support in the area — and the founders have made progress. InnoGrid recently participated in the Ion Smart and Resilient Cities Accelerator and has a relationship with Greentown Houston across the street.

Eventually, as Pettit says, InnoGrid wants to help lead Houston to becoming a hub for microgrid innovation.

"We're looking at other cities — like Chicago and Boston — and how they've deployed their microgrids and making sure we're bringing those best practices in Houston," Pettit says. "Eventually we want to be the leader in developing these microgrid best practices as the energy capital of the world."

Patel and Pettitt share more about InnoGrid and microgrid technology on the podcast. Listen to the interview below — or wherever you stream your podcasts — and subscribe for weekly episodes.


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Rice launches 'brain economy' initiative at World Economic Forum

brain health

Rice University has launched an initiative that will position “brain capital” as a key asset in the 21st century.

Rice rolled out the Global Brain Economy Initiative on Jan. 21 at the World Economic Forum in Davos, Switzerland.

“This initiative positions brain capital, or brain health and brain skills, at the forefront of global economic development, particularly in the age of artificial intelligence,” the university said in a news release.

The Rice-based initiative, whose partners are the University of Texas Medical Branch in Galveston and the Davos Alzheimer’s Collaborative, aligns with a recent World Economic Forum and McKinsey Health Institute report titled “The Human Advantage: Stronger Brains in the Age of AI,” co-authored by Rice researcher Harris Eyre. Eyre is leading the initiative.

“With an aging population and the rapid transformation of work and society driven by AI, the urgency has never been greater to focus on brain health and build adaptable human skills—both to support people and communities and to ensure long-term economic stability,” says Amy Dittmar, a Rice provost and executive vice president for academic affairs.

This initiative works closely with the recently launched Rice Brain Institute.

In its first year, the initiative will establish a global brain research agenda, piloting brain economy strategies in certain regions, and introducing a framework to guide financial backers and leaders. It will also advocate for public policies tied to the brain economy.

The report from the McKinsey Health Institute and World Economic Forum estimates that advancements in brain health could generate $6.2 trillion in economic gains by 2050.

“Stronger brains build stronger societies,” Eyre says. “When we invest in brain health and brain skills, we contribute to long-term growth, resilience, and shared prosperity.”

Rice Alliance and the Ion leader Brad Burke to retire this summer

lasting legacy

Brad Burke—a Rice University associate vice president who leads the Ion District’s Rice Alliance for Technology and Entrepreneurship and is a prominent figure in Houston’s startup community—is retiring this summer after a 25-year career at the university.

Burke will remain at the Rice Alliance as an adviser until his retirement on June 30.

“Brad’s impact on Rice extends far beyond any single program or initiative. He grew the Rice Alliance from a promising campus initiative into one of the most respected university-based entrepreneurship platforms,” Rice President Reginald DesRoches said in a news release.

During Burke’s tenure, the Rice Business School went from unranked in entrepreneurship to The Princeton Review’s No. 1 graduate entrepreneurship program for the past seven years and a top 20 entrepreneurship program in U.S. News & World Report’s rankings for the past 14 years.

“Brad didn’t just build programs — he built an ecosystem, a culture, and a reputation for Rice that now resonates around the world,” said Peter Rodriguez, dean of the business school. “Through his vision and steady leadership, Rice became a place where founders are taken seriously, ideas are rigorously supported, and entrepreneurship is embedded in the fabric of the university.”

One of Burke’s notable achievements at Rice is the creation of the Rice Business Plan Competition. During his tenure, the competition has grown from nine student teams competing for $10,000 into the world’s largest intercollegiate competition for student-led startups. Today, the annual competition welcomes 42 student-led startups that vie for more than $1 million in prizes.

Away from Rice, Burke has played a key role in cultivating entrepreneurship in the energy sector: He helped establish the Energy Tech Venture Forum along with Houston Energy and Climate Startup Week.

Furthermore, Burke co-founded the Texas University Network for Innovation and Entrepreneurship in 2008 to bolster the entrepreneurship programs at every university in Texas. In 2016, the Rice Alliance assumed leadership of the Global Consortium of Entrepreneurship Centers.

In 2023, Burke received the Trailblazer Award at the 2023 Houston Innovation Awards and was recognized by the Deshpande Foundation for his contributions to innovation and entrepreneurship in higher education.

“Working with an amazing team to build the entrepreneurial ecosystem at Rice, in Houston, and beyond has been the privilege of my career,” Burke said in the release. “It has been extremely gratifying to hear entrepreneurs say our efforts changed their lives, while bringing new innovations to market. The organization is well-positioned to help drive exponential growth across startups, investors, and the entrepreneurial ecosystem.”

Starting April 15, John “JR” Reale Jr. will serve as interim associate vice president at Rice and executive director of the Rice Alliance. He is managing director of the alliance and co-founder of Station Houston, beginning April 15. Reale is co-founder of the Station Houston startup hub and a startup investor and was also recently named director for startups and investor engagement for the Ion.

“The Rice Alliance has always been about helping founders gain advantages to realize their visions,” Reale said. “Under Brad’s leadership, the Rice Alliance has become a globally recognized platform that is grounded in trust and drives transformational founder outcomes. My commitment is to honor what Brad has built and led while continuing to serve our team and community, deepen relationships and deliver impact.”

Burke joined the Houston Innovators Podcast back in 2022. Listen to the full interview here.

Houston team uses CPRIT funding to develop nanodrug for cancer immunotherapy

cancer research

With a relative five-year survival rate of 50 percent, pancreatic cancer is a diagnosis nobody wants. At 60 percent, the prognosis for lung cancer isn’t much rosier. That’s because both cancers contain regulatory B cells (Bregs), which block the body’s natural immunity, making it harder to fight the enemies within.

Newly popular immunotherapies in a category known as STING agonists may stimulate natural cancer defenses. However, they can also increase Bregs while simultaneously causing significant side effects. But Wei Gao, assistant professor of pharmacology at the University of Houston College of Pharmacy, may have a solution to that conundrum.

Gao and her team have developed Nano-273, a dual-function drug, packaged in an albumin-based particle, that boosts the immune system to help it better fight pancreatic and lung cancers. Gao’s lab recently received a $900,000 grant from the Cancer Prevention and Research Institute of Texas (CPRIT) to aid in fueling her research into the nanodrug.

“Nano-273 both activates STING and blocks PI3Kγ—a pathway that drives Breg expansion, while albumin nanoparticles help deliver the drug directly to immune cells, reducing unwanted side effects,” Gao said in a press release. “This approach reduces harmful Bregs while boosting immune cells that attack cancer, leading to stronger and more targeted anti-tumor responses.”

In studies using models of both pancreatic and lung cancers, Nano-273 has shown great promise with low toxicity. Its best results thus far have involved using the drug in combination with immunotherapy or chemotherapy.

With the CPRIT funds, Gao and her team will be able to charge closer to clinical use with a series of important steps. Those include continuing to test Nano-273 alongside other drugs, including immune checkpoint inhibitors. Safety studies will follow, but with future patients in mind, Gao will also work toward improving her drug’s production, making sure that it’s safe and high-quality every time, so that it is eventually ready for trials.

Gao added: “If successful, this project could lead to a new type of immunotherapy that offers lasting tumor control and improved survival for patients with pancreatic and lung cancers, two diseases that urgently need better treatments."

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