Khaliah Guillory, founder of Nap Bar, says she hopes to expand to 30 locations in three years. Photo courtesy Khaliah Guillory

Houston’s Khaliah Guillory takes a 30-minute nap every day. She says this is how she’s so productive.

The habit also led to the founding of her white-glove, eco-friendly rest sanctuary business, Nap Bar.

Guillory launched the luxury sleep suites company back in 2019 to offer a unique rest experience with artificial intelligence integration for working professionals, entrepreneurs and travelers who needed a place to rest, recharge and rejuvenate. The company was named a Houston Innovation Awards finalist last year.

She says naps are backed by science. And by her professional network, too.

“Once I polled and surveyed my friends, most of them said that they also took naps during their lunch break, whether it be in their office or in their car,” says Guillory, former vice president of marketing strategy at Wells Fargo. “Once they overwhelmingly agreed that they would absolutely use a dedicated place for them to take naps if I created it, I got to work, and Nap Bar was born.”

Simply put, Guillory has effectively made it acceptable and, yes, even cool for working adults to take naps.

“I played D1 basketball at the University of Central Florida and that’s really where I learned the art of a power nap and the benefits of it,” Guillory says. “And I just continued to nap throughout my corporate career. So, in November of 2018, I retired from corporate America … I just knew I had a higher calling to do something else.”

Guillory first opened up shop in Rice Village as a beta test for her novel nap idea and it took off. She soon forged strategic partnerships with organizations like UT Health, where Nap Bar provided much-needed naps to postpartum mothers.

“Nap Bar showed what the benefits of a good nap was, specifically to postpartum moms in terms of mental stressors, productivity, and things of that nature,” Guillory says.

In November 2019, Guillory moved Nap Bar to The Galleria and says the business produced revenue from day one. However, in March 2020, she was forced to shut us down due to the COVID-19 pandemic.

“I promised myself that I was not going back to corporate America, so I pivoted. I moved forward by creating a better sleep box, with a vegan pillow mist and soy-based candle. I also became a certified sleep coach. And I just kept pivoting from there, reinventing Nap Bar as a company,” she says.

One pivot included adding a virtual reality sleep experience, MetaSnooze.

“MetaSnooze is a really cool technology that offers sleep therapy and relaxation that I curated myself,” Guillory says. “Basically, the user puts on the VR headset, and it escapes them. They're transported to places all over the country. For example, they're sitting in serene environments all the while listening to these rhythmic beats that are designed to help them release and relax. Visualizations have been scientifically proven to improve one’s mental health and mental stressors.”

Guillory initially rolled out MetaSnooze in 2020 at events like South by Southwest and kept improving the experience and building her business. By February 2024, she was curating a wellness experience at The Grammy Awards.

“That was huge for us,” Guillory says. “Being able to get feedback from the celebrities, with a handful of them even inquiring where they could purchase the headset. They were excited about the future of Nap Bar, so that was really, really cool.”

The widespread interest in Nap Bar has Guillory thinking big. She aims to expand to 30 locations in three years.

“When I say that, it sounds ambitious,” says Guillory. “It is, but I come from the school of thought that if you shoot for 30 and you get 25, no one's going to shake their finger at you for doing that, right? It's really aiming towards this big, hairy, audacious goal. I learned that in corporate America. So, what we're looking to do now is raise money like crazy.”

Guillory says she’s now looking to scale the business by partnering with like-minded investors with experience in the wellness space.

She envisions locations at national and international airports, which she says offer ripe scenarios for patrons needing to recharge. Additionally, Guillory wants to build on her initial partnership with UT Health by going onsite to curate rest experiences for patients, caregivers, faculty, staff, nurses and doctors. Colleges also offer an opportunity for growth.

“We’ve done some really cool pop-ups with the University of Houston, where we brought the rest experience on campus,” Guillory says. “That means we bring a portable, full-size, organic mattress with disposable sheets, as well as our virtual reality experience.”

Nap Bar will also serve companies, office buildings, and even sports venues, according to Guillory.

“We can literally go any and everywhere,” she says. “Our collected data suggests that we’ve just got to go where sleepy people are so that they can get restorative sleep.”

From a pricing standpoint, Nap Bar’s model is a dollar a minute. Depending on where the client is, the pop-up experience is based on a day rate or a half-day rate, starting at $4,000.

Add-ons include a full-size organic mattress or hosting a masseuse or massage therapist onsite.

With the Grammys already under her belt, Guillory would like to see Nap Bar utilized at the 2028 Olympics and build partnerships with other virtual reality companies to bring its licensed MetaSnooze software to the masses.

She also sees opportunities in athletic treatment, sleep apnea, and insomnia.

“We have done several studies with proven results that MetaSnooze has reduced mental stressors and anxiety,” Guillory says. “I'm excited about what the future holds for MetaSnooze. It definitely is a game-changer … We will continue to innovate sleep or provide sleep resources and tools in a very innovative way.”

Healing Hands is a collection of art by caregivers made to process their mentally exhausting jobs. Photo by Tre’Voy Kelly & Company

Houston Health Museum's new exhibit merges art and mental wellness

art of healing

Caring for the sick can be mentally exhausting. A new gallery of artwork at Houston’s Health Museum, created by caregivers including family members, nurses, and others in the care delivery sector, highlights these challenges.

“This program came to fruition thanks to the generous support of Unlikely Collaborators, who helped build the infrastructure for arts programming at The Health Museum,” Rose Tylinksi, the Museum’s Healing Arts Manager, tells CultureMap. “The Museum had already begun integrating art into their exhibits and community outreach with the focus on Human Health.

"Mental health and healing are important parts of human health, so we wanted to incorporate a program that impactfully addressed this through the intersection of the arts, medicine, and culture," she continues. "The arts, including music, dance, painting, writing, and more, are potent drivers of health and healing, fostering mindfulness, expression, and community. In fact, the health benefits of participating in the arts are comparable to those of regular exercise.”

“Healing Hands: A Collection of Caregiver Expressions on Mental Wellness” marks the museum’s further expansion into the arts, alongside their renowned interactive science exhibits focused on the human body and medical technology. Tylinski has organized workshops, "Paint and Process" events, and other gatherings to help caregivers articulate their struggles.

One example from the gallery is a series of short poems written by a caregiver that explores the various difficult conversations the creator often has with patients. Writing and reading poetry is a common method of helping doctors, nurses, and other caregivers process their experiences. Studies have shown that creating poems can ease feelings of grief and loneliness, both often associated with caregiving.

“It is designed to speak both to the struggles and wellness of our mental health,” says Tylinksi. “The art tells us about the fears, joys, and sacrifices that come with taking care of others. Art is used as a tool to process those experiences.”

Other pieces on display involve traditional visual art pieces.

“Healing Hands” will be on display at the Health Museum through February 2025 and is included in general admissions. For those interested in participating as artistic creators, keep an eye on the Health Museum website for announcements about workshops and events related to the creation of the art.

Founded in 1969, the Health Museum is a unique and quirky institution that consistently offers interesting explorations of the physical and mental human condition. It is the only Smithsonian-affiliated museum in the Museum District and provides experiences like allowing children to crawl through a giant colon to learn about the digestive system and interact with video game versions of humanity’s internal fauna. Despite its often whimsical nature, the Health Museum maintains a first-rate collection and consistently offers intriguing exhibits.

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This article originally ran on CultureMap.

Created through the Rice Biotech Launch Pad, Motif Neurotech is focused on developing minimally invasive bioelectronics for the treatment of psychiatric conditions. Photo via motifneuro.tech

Houston mental health tech startup receives industry validation for bioelectronic device

on the right path

A new tool in the fight against treatment-resistant depression could be on the horizon thanks to a Rice University professor.

Jacob Robinson, a professor of electrical and computer engineering and of bioengineering is also co-founder and CEO of Motif Neurotech. Created through the Rice Biotech Launch Pad, Motif Neurotech is focused on developing minimally invasive bioelectronics for the treatment of psychiatric conditions. The company closed its series A round with an oversubscribed $18.75 million earlier this year.

This week, Rice University announced that Robinson has published a peer-reviewed study in Science Advances describing his wireless device called the Digitally programmable Over-brain Therapeutic (DOT). The epidural cortical stimulator is 9 millimeters in width, meaning that it’s easily implantable but is powerful enough to send electrical stimulation to the brain through the dura, the membrane that protects the brain and spinal cord.

“It overcomes challenges by using a battery-free and wireless approach to create an implant that can deliver precise and programmable stimulation to the brain, without brain surgery,” Robinson explained in a press release.

Jacob Robinson, a professor of electrical and computer engineering and of bioengineering, is also co-founder and CEO of Motif Neurotech. Photo via motifneuro.tech

The DOT stimulator is intended to send electrical charges meant to provide neuromodulation for mental health woes including not just depression, but also obsessive compulsive disorder and post-traumatic stress disorder. The treatment could be an alternative to transcranial magnetic stimulation (TMS), a technique that has increased in popularity in recent years.

TMS uses pulsed magnetic fields to stimulate the brain. A typical TMS course includes 36 total treatments and can cause headaches. The DOT stimulator can enact the same timing patterns used in TMS, such as the intermittent theta burst stimulation (iTBS) paradigm, which has been noted to improve mood in patients, but can be achieved at home with far greater ease. Implantation takes just 20 minutes.

So far, the DOT stimulator has been implanted in both a human and a pig. In the pig, researchers noted that the electrical stimulation did not cause any damage to the brain or dura. Just as importantly, it showed stable performance for 30 days in inducing motor responses, meaning it can operate on a longer-term basis.

Motif Neurotech was founded along with Kaiyuan Yang and physicians Sunil Sheth and Sameer Sheth. The Rice Biotech Launchpad brings together local researchers like Robinson and his team with a network of industry executives. With their manuscript, entitled “Miniature battery-free epidural cortical stimulators” freshly published on the Science Advances website, big things could be coming for the bioelectronics company and for sufferers of treatment-resistant depression.

Rice team demonstrates miniature brain stimulator in humanswww.youtube.com

A Houston-founded company is targeting mothers and daughters with their teletherapy app. Photo courtesy of Passport Journeys

Houston startup addresses mother-daughter dynamic with first app of its kind

When Lacey Tezino’s mother died of cancer she vowed to help other mothers and daughters find their own ways to bond in beautiful, nurturing ways.

Tezino turned that vow into a mission that is now available for others to embark on with an online therapy app tailored specifically for the mother-daughter dynamic Passport Journeys.

The Houston-based company is billed as the first mother-daughter teletherapy application that stands out in a crowded market place on online therapy like Better Help. Tezino, the founder and CEO, partnered with seven Houston-based licensed behavioral health clinics to make the dream a reality.

The app, which launched aptly on Mother's Day, can be downloaded via Apple or Google Play, and includes video therapy sessions, journal opportunities, interactive worksheets, and help those who need access to this form of mental health help with ease.

“Outside of our target audience being mother-daughter, we are also the first teletherapy app to find prescribed activities,“ Tezino tells InnovationMap. “We are the first ones that are actually having the therapist in between their video sessions assign the mother-daughter pair intentional bonding activities. It is meant for them to spend quality time on where they are at in their relationship…there aren’t any other apps that are doing that.”

According to research from Passport Journeys, there are 85 million mothers in the United States, and the company hopes to help connect mothers and daughters in a flexible, and affordable way that differs from traditional therapy settings in a time where mental health is a priority for many.

“For your mental health in general, having these resources — there are thousands of these apps out there, but having something that is targeted therapy for your relationship is different, and the importance is your relationships ripple through your mental health,” Tezino says. “Fostering and growing this (mother-daughter) relationship is a part of mental health.”

Lacey Tezino founded Passport Journeys to provide a teletherapy platform for mothers and daughters. Photo courtesy

Boxes by Speak As One keep mental health tools feeling fresh, without overloading the user. Photo courtesy of Speak As One

New Texas-based mental health subscription box plans national launch at SXSW 2023

speak now and hold your peace

Mental health apps are so alluring, but once you’ve recorded your two-week streak and things are feeling a little more organized, it can be hard to keep going. It’s hard enough to keep up with journaling and a great bedtime routine, and many lovely self-help tools also lose their effectiveness when the novelty wears off.

A smart company might harness that novelty as its hook — and an easily distracted self-helper won’t fall off the wagon. Like many other companies in the mental health space, Speak As One will work on a subscription model, but this one won’t languish, unused on a credit card statement. The service, which plans to launch during SXSW 2023, delivers boxes of tangible mental health tools, inspiration, games, and even sensory objects that act as a monthly nudge to try something new, and curiosity takes care of the rest.

A sample box included:

  • Stress balls with short inspirational phrases by MindPanda
  • An Emotional First Aid Kit containing advice for situations as they come up, like sleeplessness and feelings of inadequacy
  • Tiny colorful putties at different resistances by Flint Rehab
  • A notebook, and two books: Athlete Mental Health Playbook and 1000 Unique Questions About Me
  • Other small items

It’s more than packing and shipping out a few toys each month. The boxes are curated with help from a licensed therapist, who leaves a personal note along with tips on how to use the items inside and additional resources. There is one type of box right now that aims to “reduce anxiety, increase mindfulness, and promote peace and balance,” but for further customization (for $10 more), the team is working on boxes tailored to first responders, veterans, athletes, and people in “recovery.”

Speak As One emphasizes community stories in its branding outside the delivery box, and uses inspiration from “influencers” (less content creators and more so people who can embody a relatable story) to build the specialty boxes. The company’s YouTube channel shares dozens of interviews with founder Julie Korioth, a former board member for Austin’s SIMS Foundation, a well-respected mental health resource for members of the local music industry.

“With hundreds of millions of people struggling with mental health, and COVID making the issue much worse, society continues to ostracize those who openly discuss mental health issues,” said Korioth in a release. “I founded this company so we can change the way the world sees, discusses, and supports mental health. Our goal is to promote empathy, connectedness, acceptance, and thoughtfulness with an innovative toolkit that caters to specific needs."

In addition to offering a nudge, these boxes could make great care packages for a loved one who is feeling introspective or going through a significant life event. It is possible to buy gift boxes, if presentation is your thing, but it’d be just as easy to repackage a box that comes before the receiver ready to appreciate the items at home.

The cost of one box is manageable at $49.99 (especially considering the retail value of products included, which the sample box far exceed), but for many subscribers this adds up fast. Luckily, there is no pressure to continue a lengthy commitment — subscriptions last between one and six months, so users have plenty of time to reconsider and sit with the items that have already been delivered.“

The goal is to meet our audience at any phase of their mental health journey,” said Korioth. “We’re creating change and a global life-long support system for children and adults dealing with mental health challenges. We simultaneously highlight businesses, the tech community, athletes, and artists doing wonderful work in this space.”

The company plans to partner with corporations to connect with employees and provide boxes to individuals the company chooses, and will turn some content into session albums with sales proceeds dedicated to mental health research.

More information and links to preorder are available at speakasone.com.

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This article originally ran on CultureMap.

MindBar founder Hailey O’Neill wanted to make sure keeping up with mental health isn't a luxury. Photo courtesy of MindBar

New Texas app makes mental health care more accessible

mental health on the mind

Much easier than finding a therapist is finding laments at the cost and accessibility of mental health care. Group therapy is more affordable, but still a pricey and intimidating commitment. Text therapy like BetterHelp costs a lot more and often feels stilted. Now, a new Texas-based platform is paving the way for another option.

Although it may not replace the need for talk therapy entirely, MindBar, which launched in Austin in July, spreads the workload of coaches and therapists across many clients, keeps things online, and ultimately sets users up at their own pace. Like MasterClass for mental health, the app reduces the barrier to entry to just $14.99 per month.

The one-way service definitely can’t listen and identify a user’s thought patterns, or recommend personalized courses of action, but it can provide a wide series of useful primers to bring into talk therapy later, augment less frequent sessions, or just facilitate some preventative care and curiosity about the mind.

“MindBar has gained considerable traction since its launch in July, and our members have enjoyed the wide range of tools to cultivate a healthy mind,” writes MindBar founder Hailey O’Neill in an email interview. “We set out to represent the idea that mental health is a right, not a luxury, and the growth we’ve already seen within our app and its members is beginning to deliver on that ambition.”

Although MindBar is not therapy, it's also not YouTube. Classes take an experience or topic — stress, grief, and self-esteem to name a few — and break it down into video modules and worksheets. Each is organized and taught by one “teacher,” whose qualifications are clearly laid out in her biography from “years of coaching,” to therapy certifications and PhDs. Instead of browsing individual videos, users join each class; it’s just a click, but it feels distinct from mental health apps that encourage tackling everything at once.

Take the “Body Image” class as an example: It contains six modules of around 15 minutes, each paired with a multi-part “worksheet" of open-ended questions and text boxes for journaling on the platform. These are then wrapped up in a friendly little print out for those who’d prefer to write. If a user decided to moderate their own experience to simulate the commitment of traditional therapy (say 50 minutes biweekly), just taking this class could fill six to twelve weeks. Compare $30 for two months of MindBar to $450 for three therapy sessions.

Since MindBar exposes a user to the theory and methods of one particular professional, further avenues open up for extra or post-curricular work. Molly Seifert teaches “Body Image.” On Seifert’s MindBar biography page, there’s a link to her website and social media. Her credentials point out her 22-episode podcast, What She Gained, adding roughly 10 hours of free content to a user’s journey, should they follow her off the platform.

There is a button to book a session — something MindBar is working on finalizing — and on Seifert’s website, she offers a more involved “Body Confidence Program” that costs $897. Most users likely will not end up signing up for a teacher’s nearly-$1,000 group therapy track. However, the opportunity is there to follow this thread from a dip of the toes to a full-blown client-provider relationship.

A 2021 report by Sapien Labs’ Mental Health Million Project 2021 found that in the United States, 37 percent of respondents who did not seek help for clinical mental health problems did so because they lacked confidence in the mental health system. Nearly as many, 34 percent, did not know what kind of help to seek. More than a quarter preferred self-help. Imagine the shift if these respondents had a self-paced, minimal commitment platform that funneled them to professionals they learned to trust.

As of August 31, 2022, there are 26 classes on MindBar. Sign up at mind-bar.com.

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This article originally ran on CultureMap.

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Texas tops ranking of best state for investors in new report

by the numbers

Texas ranks third on a new list of the best states for investors and startups.

Investment platform BrokerChooser weighed five factors to come up with its ranking:

  • 2024 Google search volume for terms related to investing
  • Number of investors
  • Number of businesses receiving investments in 2024
  • Total amount of capital invested in businesses in 2024
  • Percentage change in amount of investment from 2019 to 2024

Based on those figures, provided mostly by Crunchbase, Texas sits at No. 3 on the list, behind No. 1 California and No. 2 New York.

Especially noteworthy for Texas is its investment total for 2024: more than $164.5 billion. From 2019 to 2024, the state saw a 440 percent jump in business investments, according to BrokerChooser. The same percentages are 204 percent for California and 396 percent for New York.

“There is definitely development and diversification in the American investment landscape, with impressive growth in areas that used to fly under the radar,” says Adam Nasli, head analyst at BrokerChooser.

According to Crunchbase, funding for Texas startups is off to a strong start in 2025. In the first three months of this year, venture capital investors poured nearly $2.9 billion into Lone Star State companies, Crunchbase data shows. Crunchbase attributes that healthy dollar amount to “enthusiasm around cybersecurity, defense tech, robotics, and de-extincting mammoths.”

During the first quarter of this year, roughly two-thirds of VC funding in Texas went to just five companies, says Crunchbase. Those companies are Austin-based Apptronik, Austin-based Colossal Biosciences, Dallas-based Island, Austin-based NinjaOne, and Austin-based Saronic.

Autonomous truck company rolls out driverless Houston-Dallas route

up and running

Houston is helping drive the evolution of self-driving freight trucks.

In October, Aurora opened a more than 90,000-square-foot terminal at a Fallbrook Drive logistics hub in northwest Houston to support the launch of its first “lane” for driverless trucks—a Houston-to-Dallas route on the Interstate 45 corridor. Aurora opened its Dallas-area terminal in April and the company began regular driverless customer deliveries between the two Texas cities on April 27.

Close to half of all truck freight in Texas moves along I-45 between Houston and Dallas.

“Now, we are the first company to successfully and safely operate a commercial driverless trucking service on public roads. Riding in the back seat for our inaugural trip was an honor of a lifetime – the Aurora Driver performed perfectly and it’s a moment I’ll never forget,” Chris Urmson, CEO and co-founder of Pittsburgh-based Aurora, said in a news release.

Aurora produces software that controls autonomous vehicles and is known for its flagship product, the Aurora Driver. The software is installed in Volvo and Paccar trucks, the latter of which includes brands like Kenworth and Peterbilt.

Aurora previously hauled more than 75 loads per week under the supervision of vehicle operators from Houston to Dallas and Fort Worth to El Paso for customers in its pilot project, including FedEx, Uber Freight and Werner. To date, it has completed over 1,200 miles without a driver.

The company launched its new Houston to Dallas route with customers Uber Freight and Hirschbach Motor Lines, which ran supervised commercial pilots with Aurora.

“Transforming an old school industry like trucking is never easy, but we can’t ignore the safety and efficiency benefits this technology can deliver. Autonomous trucks aren’t just going to help grow our business – they’re also going to give our drivers better lives by handling the lengthier and less desirable routes,” Richard Stocking, CEO of Hirschbach Motor Lines, added in the statement.

The company plans to expand its service to El Paso and Phoenix by the end of 2025.

“These new, autonomous semis on the I-45 corridor will efficiently move products, create jobs, and help make our roadways safer,” Gov. Greg Abbott added in the release. “Texas offers businesses the freedom to succeed, and the Aurora Driver will further spur economic growth and job creation in Texas. Together through innovation, we will build a stronger, more prosperous Texas for generations.”

In July, Aurora said it raised $820 million in capital to fuel its growth—growth that’s being accompanied by scrutiny.

In light of recent controversies surrounding self-driving vehicles, the International Brotherhood of Teamsters, whose union members include over-the-road truckers, recently sent a letter to Lt. Gov. Dan Patrick calling for a ban on autonomous vehicles in Texas.

“The Teamsters believe that a human operator is needed in every vehicle—and that goes beyond partisan politics,” the letter states. “State legislators have a solemn duty in this matter to keep dangerous autonomous vehicles off our streets and keep Texans safe. Autonomous vehicles are not ready for prime time, and we urge you to act before someone in our community gets killed.”

Houston cell therapy company launches second-phase clinical trial

fighting cancer

A Houston cell therapy company has dosed its first patient in a Phase 2 clinical trial. March Biosciences is testing the efficacy of MB-105, a CD5-targeted CAR-T cell therapy for patients with relapsed or refractory CD5-positive T-cell lymphoma.

Last year, InnovationMap reported that March Biosciences had closed its series A with a $28.4 million raise. Now, the company, co-founded by Sarah Hein, Max Mamonkin and Malcolm Brenner, is ready to enroll a total of 46 patients in its study of people with difficult-to-treat cancer.

The trial will be conducted at cancer centers around the United States, but the first dose took place locally, at The University of Texas MD Anderson Cancer Center. Dr. Swaminathan P. Iyer, a professor in the department of lymphoma/myeloma at MD Anderson, is leading the trial.

“This represents a significant milestone in advancing MB-105 as a potential treatment option for patients with T-cell lymphoma who currently face extremely limited therapeutic choices,” Hein, who serves as CEO, says. “CAR-T therapies have revolutionized the treatment of B-cell lymphomas and leukemias but have not successfully addressed the rarer T-cell lymphomas and leukemias. We are optimistic that this larger trial will further validate MB-105's potential to address the critical unmet needs of these patients and look forward to reporting our first clinical readouts.”

The Phase 1 trial showed promise for MB-105 in terms of both safety and efficacy. That means that potentially concerning side effects, including neurological events and cytokine release above grade 3, were not observed. Those results were published last year, noting lasting remissions.

In January 2025, MB-105 won an orphan drug designation from the FDA. That results in seven years of market exclusivity if the drug is approved, as well as development incentives along the way.

The trial is enrolling its single-arm, two-stage study on ClinicalTrials.gov. For patients with stubborn blood cancers, the drug is providing new hope.