The new $16 million Comcast facility is another feather in the cap of Fort Bend County, which is booming with new business. Courtesy of Comcast

At Comcast's new $16 million technology center in Missouri City, technicians for the internet and cable TV provider can "test drive" new product and services at a demo lab and can take classes at Comcast University. It's a far cry from the stereotypical workplace of the "cable guy."

The center represents a cutting-edge expansion for Comcast — and represents yet another feather in the economic-growth cap of Missouri City and Fort Bend County.

On June 19, officials from Comcast, Missouri City government, and the Fort Bend Economic Development Council debuted the 32,000-square-foot center. The center is at 551 Buffalo Lakes Dr., near the intersection of Texas Freeway and Independence Boulevard. Aside from the demo lab and Comcast University classrooms, the center features more than 100 workstations and 15 conference rooms.

The center employs more than 300 technicians, Comcast Business and Xfinity sales professionals. Service technicians install and maintain internet, video, voice, and home security services for residential and business customers in Missouri City and nearby areas, while network technicians build and maintain Comcast's local fiber-optic system.

Employees at the new center previously worked at other offices in the Houston metro area but live in Missouri City and surrounding communities. More than 1,200 people work at Comcast's 10 technology centers throughout the Houston area.

Michael Bybee, director of external communications at Comcast, says Missouri City was picked for the new center because of its strong economic growth and its proximity to major highways and, ultimately, "to bring our employees closer to customers."

Missouri City and Fort Bend County are gaining more potential Comcast customers by the day. From April 2010 to July 2018, the population of Missouri City grew 12.3 percent, according to the U.S. Census Bureau. For Fort Bend County, the population growth rate during the same period stood at 34.7 percent.

Economic growth has accompanied that population growth. Last year, the Comcast center was among several economic development wins scored by Missouri City. An $85 million, 550,000-square-foot Best Buy distribution center and a 200,000-square-foot Warren Valve warehouse and distribution center were two of the other wins.

Fort Bend County as a whole is enjoying economic success. For instance, discount retailer Dollar Tree said in February that it's building a $130 million distribution center on a 140-acre site in Rosenberg that will employ more than 300 people. The company operates more than 1,600 Dollar Tree and Family Dollar stores in Texas.

The 1.2-million-square-foot distribution center, on Spur 10 near Klosterhoff Road, is scheduled to open in the summer of 2020.

"When you have a company like Dollar Tree seeing the opportunity that we offer, it just adds to our strengths and builds on our assets," Bret Gardella, executive director of Rosenberg Development Corp., said in a Dollar Tree news release.

The economic growth in Missouri City, Rosenberg and other places in Fort Bend County isn't likely to subside, at least for the next several decades. A report from the University of Houston's Hobby School of Public Affairs predicts Fort Bend County will end up being the state's third-fastest-growing county from 2010 to 2050.

"Fort Bend County has continued to top lists for livability and economic success — and there is no sign of slowing down," the Fort Bend Economic Development Council says on its website. "Residents and businesses agree that there's no place better to live or work."

Contributing to Fort Bend County's draw is the presence of five business parks — two in Missouri City, and one each in Rosenberg, Sugar Land, and Stafford. The council touts Fort Bend County as "the hub for industrial development."

Courtesy of Comcast

Aside from the demo lab and Comcast University classrooms, the center features more than 100 workstations and 15 conference rooms.

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Rice Alliance and the Ion leader Brad Burke to retire this summer

lasting legacy

Brad Burke—a Rice University associate vice president who leads the Ion District’s Rice Alliance for Technology and Entrepreneurship and is a prominent figure in Houston’s startup community—is retiring this summer after a 25-year career at the university.

Burke will remain at the Rice Alliance as an adviser until his retirement on June 30.

“Brad’s impact on Rice extends far beyond any single program or initiative. He grew the Rice Alliance from a promising campus initiative into one of the most respected university-based entrepreneurship platforms,” Rice President Reginald DesRoches said in a news release.

During Burke’s tenure, the Rice Business School went from unranked in entrepreneurship to The Princeton Review’s No. 1 graduate entrepreneurship program for the past seven years and a top 20 entrepreneurship program in U.S. News & World Report’s rankings for the past 14 years.

“Brad didn’t just build programs — he built an ecosystem, a culture, and a reputation for Rice that now resonates around the world,” said Peter Rodriguez, dean of the business school. “Through his vision and steady leadership, Rice became a place where founders are taken seriously, ideas are rigorously supported, and entrepreneurship is embedded in the fabric of the university.”

One of Burke’s notable achievements at Rice is the creation of the Rice Business Plan Competition. During his tenure, the competition has grown from nine student teams competing for $10,000 into the world’s largest intercollegiate competition for student-led startups. Today, the annual competition welcomes 42 student-led startups that vie for more than $1 million in prizes.

Away from Rice, Burke has played a key role in cultivating entrepreneurship in the energy sector: He helped establish the Energy Tech Venture Forum along with Houston Energy and Climate Startup Week.

Furthermore, Burke co-founded the Texas University Network for Innovation and Entrepreneurship in 2008 to bolster the entrepreneurship programs at every university in Texas. In 2016, the Rice Alliance assumed leadership of the Global Consortium of Entrepreneurship Centers.

In 2023, Burke received the Trailblazer Award at the 2023 Houston Innovation Awards and was recognized by the Deshpande Foundation for his contributions to innovation and entrepreneurship in higher education.

“Working with an amazing team to build the entrepreneurial ecosystem at Rice, in Houston, and beyond has been the privilege of my career,” Burke said in the release. “It has been extremely gratifying to hear entrepreneurs say our efforts changed their lives, while bringing new innovations to market. The organization is well-positioned to help drive exponential growth across startups, investors, and the entrepreneurial ecosystem.”

Starting April 15, John “JR” Reale Jr. will serve as interim associate vice president at Rice and executive director of the Rice Alliance. He is managing director of the alliance and co-founder of Station Houston, beginning April 15. Reale is co-founder of the Station Houston startup hub and a startup investor and was also recently named director for startups and investor engagement for the Ion.

“The Rice Alliance has always been about helping founders gain advantages to realize their visions,” Reale said. “Under Brad’s leadership, the Rice Alliance has become a globally recognized platform that is grounded in trust and drives transformational founder outcomes. My commitment is to honor what Brad has built and led while continuing to serve our team and community, deepen relationships and deliver impact.”

Burke joined the Houston Innovators Podcast back in 2022. Listen to the full interview here.

Houston team uses CPRIT funding to develop nanodrug for cancer immunotherapy

cancer research

With a relative five-year survival rate of 50 percent, pancreatic cancer is a diagnosis nobody wants. At 60 percent, the prognosis for lung cancer isn’t much rosier. That’s because both cancers contain regulatory B cells (Bregs), which block the body’s natural immunity, making it harder to fight the enemies within.

Newly popular immunotherapies in a category known as STING agonists may stimulate natural cancer defenses. However, they can also increase Bregs while simultaneously causing significant side effects. But Wei Gao, assistant professor of pharmacology at the University of Houston College of Pharmacy, may have a solution to that conundrum.

Gao and her team have developed Nano-273, a dual-function drug, packaged in an albumin-based particle, that boosts the immune system to help it better fight pancreatic and lung cancers. Gao’s lab recently received a $900,000 grant from the Cancer Prevention and Research Institute of Texas (CPRIT) to aid in fueling her research into the nanodrug.

“Nano-273 both activates STING and blocks PI3Kγ—a pathway that drives Breg expansion, while albumin nanoparticles help deliver the drug directly to immune cells, reducing unwanted side effects,” Gao said in a press release. “This approach reduces harmful Bregs while boosting immune cells that attack cancer, leading to stronger and more targeted anti-tumor responses.”

In studies using models of both pancreatic and lung cancers, Nano-273 has shown great promise with low toxicity. Its best results thus far have involved using the drug in combination with immunotherapy or chemotherapy.

With the CPRIT funds, Gao and her team will be able to charge closer to clinical use with a series of important steps. Those include continuing to test Nano-273 alongside other drugs, including immune checkpoint inhibitors. Safety studies will follow, but with future patients in mind, Gao will also work toward improving her drug’s production, making sure that it’s safe and high-quality every time, so that it is eventually ready for trials.

Gao added: “If successful, this project could lead to a new type of immunotherapy that offers lasting tumor control and improved survival for patients with pancreatic and lung cancers, two diseases that urgently need better treatments."

Houston booms as No. 2 U.S. metro for new home construction

Construction Boom

Driven by population growth, more residential rooftops are popping up across Houston and the rest of Texas than anywhere else in America.

Using data from the U.S. Census Bureau and Zillow, Construction Coverage found 65,747 new residential units were authorized in greater Houston in 2024. That figure landed Houston in second place among major metro areas for the total number of housing permits, including those for single-family homes, apartments, and condos.

Just ahead of Houston was the Dallas-Fort Worth Metroplex, which took first place with 71,788 residential permits approved in 2024. In third place was the country’s largest metro, New York City (57,929 permits).Elsewhere in Texas, the Austin metro ranked sixth (32,294 permits), and the San Antonio metro ranked 20th (14,857 permits).

Construction Coverage also sorted major metro areas based on the number of new housing units authorized per 1,000 existing homes in 2024. Raleigh, North Carolina, held the No. 1 spot (28.8 permits per 1,000 existing homes), followed by Austin at No. 2 (28.6), DFW at No. 3 (22.2), Houston at No. 4 (21.6), and San Antonio at No. 13 (13.6).

A Newsweek analysis of Census Bureau data shows building permits for 225,756 new residential units were approved in 2024 in Texas — a trend fueled largely by activity in DFW, Houston, Austin, and San Antonio. That put Texas atop the list of states building the most residential units for the year.

Through the first eight months of last year, 145,901 permits for new residential units were approved in Texas, according to Census Bureau data. That’s nearly 80,000 permits shy of the 2024 total.

Among the states, Construction Coverage ranks Texas sixth for the number of residential building permits approved in 2024 per 1,000 existing homes (17.9).

Extra housing is being built in Texas to meet demand spurred by population growth. From April 2020 to July 2024, the state’s population increased 7.3 percent, the Census Bureau says.

While builders are busy constructing new housing in Texas, they’re not necessarily profiting a lot from homebuilding activity.

“Market conditions remain challenging, with two-thirds of builders reporting they are offering incentives to move buyers off the fence,” North Carolina homebuilder Buddy Hughes, chairman of the National Association of Home Builders, said in a December news release. “Meanwhile, builders are contending with rising material and labor prices, as tariffs are having serious repercussions on construction costs.”