Houston digital health startup acquired by Illinois-based company

M&A moves

Houston-based Melax Tech has been acquired. Photo via MelaxTech.com

A Houston startup has exited to a clinical terminology management and data quality solutions company.

Melax Technologies Inc., an artificial intelligence and natural language processing technology company, has been acquired by Intelligent Medical Objects, which is headquartered in the Chicago area. It's the first acquisition for IMO, and the deal will allow for the company to expand its offerings to various segments in the health care market.

"Today marks an exciting moment for IMO as we complete our first acquisition,” says Ann Barnes, CEO at IMO, in a news release. “Combining Melax Tech’s analytics and NLP capabilities with IMO’s clinical terminology and data quality platform will enable healthcare organizations to have a more comprehensive solution for both clinical operation and research.

"The acquisition will also help extend our state-of-the-art capabilities to payer, pharmaceutical, and life science companies,” she continues.

Founded in 2017 and based out of the Texas Medical Center Innovation Factory, Melax Tech is used by over 650 organizations for clinical trials optimization and more.

“We are thrilled to join forces with IMO and combine our NLP expertise with their clinical terminology and knowledge management solutions,” says Andre Pontin, CEO of Melax Tech, in the release. “Together, we will be able to offer healthcare organizations a powerful suite of solutions that will enable them to improve patient outcomes and reduce costs.”

Melax Tech has entered into a handful of strategic partnerships over its six-year existence and raised $600,000 in grant funding from the National Institute of Health and National Institute of Allergy and Infectious Diseases.

The details of the acquisition transaction have not been disclosed.

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Houston-based Melax Tech has developed multiple Natural language processing tools that are used by more than 650 health care and life science organizations. Photo via MelaxTech.com

Houston-based language processing co. lands latest partnership with UC Irvine

teamwork

Melax Tech Partners, a leader in natural language technology processing, announced a new partnership with the University of California at Irvine that will help researchers derive insights from the UCI Health Data Science Platform’s electronic health records system and improve patient care.

Melax will implement its signature text annotation tool LANN to pull information from clinical notes, and its CLAMP product to develop natural language processing customizations through the use of AI, according to a statement from the company.

“There has been a strong desire among UCI researchers to have the capability to analyze free-text clinical narrative data using cutting-edge NLP technologies," Kai Zheng, chief research information officer at UCI Health Affairs, says in a statement. "We are delighted to have this opportunity to work with Melax Tech to deploy their AI-driven annotation and analytics tools to help our researchers advance their research agenda by leveraging the vast amount of free-text data that our health system has accumulated in the past two decades.”

Natural language processing, or NLP, allows organizations and healthcare groups to sift through and analyze massive amounts of data at a rapid rate through the use of machine learning and AI. Houston-based Melax Tech, founded in 2017, has developed multiple NLP tools that are used by more than 650 health care and life science organizations, according to its website.

In addition to the recent partnership with UC Irvine, Melax has also recently partnered with Vanderbilt University Medical Center and the University of Western Pennsylvania on similar clinical projects.

Melax has also used its platforms to pull vital information from datasets relating to COVID-19, in both medical and social settings.

In March 2022, it was awarded a Phase 1 NIH Award, valued at $300,000, to develop informatics tools based on COVID-19 datasets with the San Diego Supercomputer Center at UC San Diego. The tool aims to help researchers better understand vast amounts of virus-related data and connect findings with other similar results.

In August, Melax also received another $300,000 grant from the National Institute of Allergy and Infectious Diseases to develop NLP-based algorithms that will "model, extract and synthesize vaccine misinformation from multiple popular social media sources," according to a statement. Melax will also develop a visualization that presents its findings on the misinformation into a compressible format.

"This is a very real topic affecting culture at present," Andre Pontin, CEO at Melax Tech, says in a statement. "And shows that we as a collective business and group of experts continue to be on the cutting-edge of science in the NLP and AI domain."

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9 innovation & networking events for Houstonians to attend at SXSW 2025

A Houstonian's Guide to SXSW

South by Southwest, Austin's signature hybrid music, film and interactive festival, returns to the Texas capital this month, running March 7 through 15.

In the business and innovation sector, the festival fuses together SXSW Edu for educators at the beginning of the week and SXSW Interactive, which is one of the largest gatherings in the world of innovators, technologists, artists, startups, investors and policy-makers. SXSW is a powerful international magnet for creators and the people who serve them.

I started coming to Austin for SXSW in 1999, a few years after the Interactive portion (nicknamed "Spring Break for Nerds") launched and when the entire conference of 6,000 attendees fit into the Austin Convention Center. Back then, you could rub shoulders with famous bloggers who challenged established tech journalists in the hallways, multimedia artists handing out bootleg CD-ROMS, and hard-core geeks setting web standards and laws related to technology that we enjoy today.

SXSW, like Austin itself, has grown up quite a bit in the last two decades and has fended off the common Austin refrain of "It was better X years ago," as everything has become more commercial, less "authentic" and more expensive. SXSW officially sells tickets or badges for $2295.00 at the Platinum level (with cheaper options as well) providing access to stand in lines with hundreds of your friends for the most popular keynotes and panels.

One critical tradition of SXSW and part of the relentless motivation to "Keep Austin Weird" is the dozens of unofficial side events that pop up during the event all across the city. These unofficial events and activations typically provide networking opportunities fueled by the draw of internet-famous speakers, free food, and free alcohol. As SXSW has grown exponentially, it still seems to retain its charm and quirkiness as not quite a music festival, like Bonnaroo or Lollapalooza, nor a film festival like Sundance or Tribeca, and certainly not a traditional tech conference like CES. I like to think of it as a Carnival with many things to do and see but without a specific agenda or outcome. Since COVID and the financial market retraction, these parties and happy hours have become a lot more restrained, but they still exist if you know where to look.

This article is designed to guide you through the highlights, both official and unofficial, of SXSW with a focus on professional business development with a strong bent toward networking with tech startups. Here's what not to miss.

Friday, March 7

Equitech Texas Welcome Breakfast
9–11 a.m.
Inn Cahoots, 1221 E 6th St.
A breakfast gathering of people involved with Impact Investing and Equity Tech, led by Laurie Felker Jones

Startup Superconnector featuring Practice Pitch
11 a.m.–4 p.m.
Funded House, 315 Lavaca St.
This is a "Pop Up Pitch" event designed to help startups with their investor pitches by putting them in the same room with investors and professional service providers.

Startup Crawl at SXSW 2025
5 p.m. for Backstage VIP
6–9 p.m.
Capital Factory, 701 Brazos St., Suite 1600

Startup Crawl is arguably the most important unofficial event during SXSW where hundreds of startups showcase their offerings in a huge trade show, party format.

Saturday, March 8

The Red ThreadX
607 W. Third Street, 29th Floor
Curated content, strategic connections and actionable insights for military and defense-oriented businesses

SXSW 2025: Dolphin Tank
8–10:30 a.m.
FQ Lounge: Waller Creek Boathouse, 74 Trinity St.
In partnership with Amazon and The Female Quotient, this event is dedicated to championing women entrepreneurs.

Sunday, March 9

2025 TXST SXSW Lab: The Bobcat Den
1:30–8:00 p.m.
The Bobcat Den @ SXSW, Q-Branch 200 E. Sixth St., Suite 310
PROMO CODE: MICHAELBESTVIP
The TXST SXSW Lab: The Bobcat Den is a dynamic, all-day event that showcases Texas State University’s cutting-edge research, industry collaborations, and student innovation.

Monday, March 10

Founded in Texas - For Women Founders
9 a.m.–12:30 p.m.
Brown Advisory, 200 W. Sixth St., Suite 1700
Project W, The Artemis Fund, HearstLab and Brown Advisory have joined forces to bring you Founded in Texas, an investor feedback session designed to support Texas-based women who are founders of B2B and B2B2C technology companies.

Inaugural Texas House
11:00 a.m. on Monday, March 10, until 11:59 p.m. on Tuesday March 11
315 Lavaca St.
More than ever, Texans are leading at the frontiers of technology, entrepreneurship, and culture. See the full agenda

Tuesday, March 11

Super Connectors Meet Up
4–5 p.m.
Hilton Austin Downtown, 500 E. Fourth St.,Room 412
*Badge-only event
"Superconnectors," tor those who seem hyper-connected to large networks of people, are naturally drawn to SXSW. They thrive in a creative and innovative environment, affording them countless opportunities to meet interesting people. Meet some here.

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This information and more can be found at Marc Nathan's VIP Insider’s Guide to SXSW.


Houston space tech co.'s lunar lander touches down on moon — condition unknown

Lunar Landing

A privately owned lunar lander touched down on the moon Thursday, but as the minutes dragged on, flight controllers could not confirm its condition or whether it was even upright near the south pole.

The last time Intuitive Machines landed a spacecraft on the moon, a year ago, it ended up sideways.

The company's newest Athena lander dropped out of lunar orbit as planned, carrying an ice drill, a drone and two rovers for NASA and others. The hourlong descent appeared to go well, but it took a while for Mission Control to confirm touchdown.

“We're on the surface,” reported mission director and co-founder Tim Crain. A few minutes later, he repeated, "It looks like we're down ... We are working to evaluate exactly what our orientation is on the surface.”

Launched last week, Athena was communicating with controllers more than 230,000 miles away and generating solar power, officials said. But nearly a half-hour after touchdown, Crain and his team still were unable to confirm if everything was all right with the 15-foot lander. NASA and Intuitive Machines abruptly ended their live webcast, promising more updates at a news conference later in the afternoon.

“OK team, keep working the problem," Crain urged.

Intuitive Machines last year put the U.S. back on the moon despite its lander tipping on its side.

Another U.S. company Firefly Aerospace on Sunday became the first to achieve complete success with its commercial lunar lander. A vacuum already has collected lunar dirt for analysis and a dust shield has shaken off the abrasive particles that cling to everything.

Intuitive Machines was aiming this time for a mountain plateau just 100 miles from the south pole, much closer than before.

This week's back-to-back moon landings are part of NASA’s commercial lunar delivery program meant to get the space agency’s experiments to the gray, dusty surface and jumpstart business. The commercial landers are also seen as scouts for the astronauts who will follow later this decade under NASA's Artemis program, the successor to Apollo.

NASA officials said before the landing that they knew going in that some of the low-cost missions would fail. But with more private missions to the moon, that increased the number of experiments getting there.

NASA spent tens of millions of dollars on the ice drill and two other instruments riding on Athena, and paid an additional $62 million for the lift. Most of the experiments were from private companies, including the two rovers. The rocket-powered drone came from Intuitive Machines — it's meant to hop into a permanently shadowed crater near the landing site in search of frozen water.

Intuitive Machines' Trent Martin said before the flight that Athena needed to land upright in order for the drone and rovers to deploy.

To lower costs even more, Intuitive Machines shared its SpaceX rocket launch with three spacecraft that went their separate ways. Two of them — NASA’s Lunar Trailblazer and AstroForge’s asteroid-chasing Odin — are in jeopardy.

NASA said this week that Lunar Trailblazer is spinning without radio contact and won’t reach its intended orbit around the moon for science observations. Odin is also silent, with its planned asteroid flyby unlikely.

As for Athena, Intuitive Machines made dozens of repairs and upgrades following the company’s sideways touchdown by its first lander. It still managed to operate briefly, ending America’s moon-landing drought of more than 50 years.

Until then, the U.S. had not landed on the moon since Apollo 17 in 1972. No one else has sent astronauts to the moon, the overriding goal of NASA’s Artemis program. And only four other countries have successfully landed robotic spacecraft on the moon: Russia, China, India and Japan.

Houston scientists make breakthrough in hearing science and treatment research

sounds good

Researchers at Baylor College of Medicine and the Jan and Dan Duncan Neurological Research Institute at Texas Children’s Hospital have successfully mapped which cell populations are responsible for processing different types of sounds.

Working with a team at the Oregon Health & Science University, the Houston scientists have classified where in the cochlear nucleus our brains connect with various sounds, including speech and music. The research was published in the new edition of Nature Communications.

“Understanding these cell types and how they function is essential in advancing treatments for auditory disorders,” Matthew McGinley, assistant professor of neuroscience at Baylor, said in a release. “Think of how muscle cells in the heart are responsible for contraction, while valve cells control blood flow. The auditory brainstem operates in a similar fashion — different cell types respond to distinct aspects of sound.”

Though scientists have long thought that there are distinct types of cells in the cochlear nucleus, they didn’t have tools to distinguish them until now.

Lead author on the study, Xiaolong Jiang, associate professor of neuroscience at Baylor, added: “This study not only confirms many of the cell types we anticipated, but it also unveils entirely new ones, challenging long-standing principles of hearing processing in the brain and offering fresh avenues for therapeutic exploration.”

Jiang and his team have cooked up a comprehensive cellular and molecular atlas of the cochlear nucleus, which will help them to create more targeted and more effective treatments for patients struggling with their hearing.

The strategies that aided them in creating these tools included single-nucleus RNA sequencing, which made it possible to define neuronal populations on a molecular level. Phenotypic categorizations of the cells were made possible with patch sequencing.

This is a watershed moment for the development of targeted treatments for individuals with auditory disorders, including those with impaired function in the auditory nerve, for whom cochlear implants don’t work.

“If we can understand what each cell type is responsible for, and with the identification of new subtypes of cells, doctors can potentially develop treatments that target specific cells with greater accuracy,” McGinley explains. “These findings, thanks to the work of our collaborative team, make a significant step forward in the field of auditory research and get us closer to a more personalized treatment for each patient.”

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