3 Houston innovators to know this week

who's who

This week's innovators to know roundup includes Patrick Jankowski of the Greater Houston Partnership, Deanea LeFlore of The Ion, and Dr. Mehdi Razavi of the Texas Heart Institute. Photos courtesy

Editor's note: In this week's Monday roundup of Houston innovators, I'm introducing you to three innovators across the city — from the Greater Houston Partnership, The Ion, and Texas Heart Institute.

Patrick Jankowski, senior vice president of research

The Greater Houston Partnership hosted its annual economic outlook event online this week. Photo courtesy of the GHP

At the GHP's annual economic outlook, Patrick Jankowski, senior vice president of research, predicts that 2021 will be a "bipolar year." The first and second halves of the year are going to look different, Jankowski says, it's just a matter of how different at this point. In addition to the vaccine and COVID case numbers, the things the GHP as well as Houston businesses are watching is the new Biden Administration.

"We won't see any significant growth in the economy until we get to the second half of the year," he says. Read more.

Deanea LeFlore, director of partnerships at The Ion

Deanea LeFlore, director of partnerships at The Ion, joins this week's episode of the Houston Innovators Podcast. Photo courtesy of Station Houston

Houston is just a few months away from being able to walk into The Ion, and the organization's director of partnerships, Deanea LeFlore, hopes that when that happens, they are entering a innovation hub reflective of the city.

"I think that when people walk into The Ion, what's personally important to me, is that it looks like Houston so that you see yourself reflected in the people in the building as well as the programming," LeFlore says. "That's my biggest hope and aspiration, and I believe we are well on track to be able to deliver on exactly that."

LeFlore shares more on what she's been working on — from online programming to growing partnerships at The Ion. Listen to the podcast and read more.

Dr. Mehdi Razavi, director of Electrophysiology Clinical Research & Innovations at the Texas Heart Institute

A medical device coming out of the Texas Heart Institute has been recognized for its innovation. Photo via THI

A new technology out of Houston's Texas Heart Institute's was named the top future medical product design worldwide last month as part of the annual Create the Future Design contest. The med device, which allows for pain-free defibrillation, is being developed by THI's Electrophysiology Clinical Research & Innovations team in conjunction with scientists at Rice University and UCLA, the technology allows doctors to place up to 12 tiny nodes around the heart to pace and defibrillate the heart without using a shock.

The technology will be most useful for atrial fibrillation and ventricular fibrillation, which can lead to sudden death, stroke, and congestive heart failure, according to Dr. Mehdi Razavi, the head investigator on this project and leader of the THI team.

"It's extremely painful. It's like someone takes a two by four and just pounds you from the inside in the chest, or a horse kicking you in the chest," Razavi says. He went on to add: "I have actually one patient who was a Vietnam veteran. He said nothing that he faced in battle was as disconcerting—not just because of the pain, but the fact that you don't know when the pain is when the shock is about to happen. That anxiety is just overwhelming." Read more.

A medical device coming out of the Texas Heart Institute has been recognized for its innovation. Photo via THI

Houston innovation team wins global award for painless heart technology

heart of gold

Houston's Texas Heart Institute's pain-free defibrillation technology was named the top future medical product design worldwide last month as part of the annual Create the Future Design contest.

The tiny technology aims to change the way cardiac arrhythmias are managed and remove the often traumatizing pain associated with their treatment. Developed by THI's Electrophysiology Clinical Research & Innovations team in conjunction with scientists at Rice University and UCLA, the technology allows doctors to place up to 12 tiny nodes around the heart to pace and defibrillate the heart without using a shock.

The technology will be most useful for atrial fibrillation and ventricular fibrillation, which can lead to sudden death, stroke, and congestive heart failure, according to Dr. Mehdi Razavi, the head investigator on this project and leader of the THI team. Razavi says winning the award "speaks to the need" of a new solution in the field as the shocks associated with traditional implantable cardioverter-defibrillators, or ICDs, can cause severe PTSD among patients.

"It's extremely painful. It's like someone takes a two by four and just pounds you from the inside in the chest, or a horse kicking you in the chest," Razavi says. He went on to add: "I have actually one patient who was a Vietnam veteran. He said nothing that he faced in battle was as disconcerting—not just because of the pain, but the fact that you don't know when the pain is when the shock is about to happen. That anxiety is just overwhelming."

Instead of shocking the patient's heart in a central location, the nodes spread energy needed to pace the heart at the correct rate throughout the muscle based on their location. This dilutes the feeling of a sudden jolt, and Razavi says, defibrillation using his technology could go unnoticed in patients.

In addition to this game-changing possibility, the new technology is physically safer in many ways, too. The miniaturized battery-less pacing system is free of traditional wires that send electrical pulses to the heart, known as leads. These leads can dislodge and fracture within the body and can cause infection.

The technology's wireless and miniature nature also allows doctors to better access regions of the heart that currently are difficult to reach with bulkier ICDs. Each node can be individually programmed and can stimulate different regions of the heart in different ways, as well.

A cross disciplinary team developed the device. Aydin Babakhani, an associate professor in physical and wave electronics at UCLA first developed the nodes to stimulate electricity for non-medical purposes. Behnaam Aazhang, the J.S. Abercrombie Professor of Electrical and Computer Engineering and the Director of the Rice Neuroengineering Initiative, first introduced Razavi to Babakhani, and the trio worked together to bring the technology to the medical arena, along with about 15 to 20 other medical professionals and students.

The team at Rice is continuing to develop the hardware for clinical use. And studies on the use of defibrillation through these nodes across the heart are being conducted out to the Texas Heart Institute's research lab. Razavi and his team are currently conducting preclinical studies on the new form of treatment and aims to roll it out for clinical use in the next three to five years.

From Houston inventors being recognized to Chevron's latest investment, here's what innovation news you need to know. Photo by Dwight C. Andrews/Greater Houston Convention and Visitors Bureau

Chevron makes another investment, Houston researchers nationally recognized, and more innovation news

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Houston's innovation news hasn't quite slowed yet for the holidays. This most recent news roundup includes lots of money raised, a new contract for a Houston startup, innovators recognized and more.

For more daily innovation news, subscribe to InnovationMap's newsletter, which goes out every weekday at 7 am.

Chevron Technology Ventures invests in Texas company

Courtesy of CTV

Houston-based Chevron Technology Ventures has contributed to Austin-based motor tech company Infinitum Electric's $12.5 million Series B round of financing. New Mexico-based Cottonwood Technology Fund and includes participation AJAX Strategies and other individual investors.

The company plans to use the funds to build out its research and development, engineering, supply chain, and production teams.

"Infinitum's mission aligns well with our goals for the Future Energy Fund," says Barbara Burger, president of CTV, in a release. "The purpose of the Future Energy Fund is to invest in breakthrough energy technologies that reflect Chevron's commitment to lower emission energy sources and that are integral to low-carbon and efficient value chains."

4 Houston researchers named fellows of the National Academy of Inventors

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The National Academy of Inventors named 168 academic innovators to NAI Fellow status — and four conduct their research right here in Houston. The program "highlights academic inventors who have demonstrated a spirit of innovation in creating or facilitating outstanding inventions that have made a tangible impact on quality of life, economic development and the welfare of society," reads the news release.

The four Houston inventors and their institutions are as follows:

List ranks Houston's fastest growing companies

Chart via Grojo.com

Growjo named the 100 fastest-growing companies in Houston for 2019, and, while the study notes the city's large oil and gas and medical industries, also acknowledges its growing tech and software scene. The companies were selected by a myriad of factors.

"Our algorithm is based on multiple datasets including employee growth, estimated revenue growth, valuations, quality and quantity of funding, hiring announcements, current job openings, leadership team announcements, and numerous other growth triggers," reads the website.

The top five companies on the list are:

  1. Midcoast Energy, which has 183 employees and a 17 percent employee growth rate.
  2. ibüümerang, which has 528 employees, and a 633 percent employee growth rate.
  3. Arion, which has 136 employees and a 216 percent employee growth rate.
  4. GoExpedi, which as 59 employees and a 119 percent employee growth rate.
  5. Code Ninjas, which has 338 employees and a 63 percent employee growth rate.

For the full list, visit Growjo.com.

TMCx company wins awards 

Image via abilitechmedical.com

Abilitech Medical, which recently completed the TMCx program, has taken home some wins in Minnesota, where it's based. The company was named named among the state's topmed tech companies by the Minnesota High Tech Association at the 2019 TEKNE awards and 2019, as well as the grand prize winner and top woman-led business by the University of Minnesota's business school at its 2019 Minnesota Cup competition.

The medical device company's technology includes the Abilitech™ Assist, which assists patients with Multiple Sclerosis, rehabilitating from stoke, or other conditions with eating, drinking, and using a computer.

"We've met so many people whose lives will be changed with this innovation," says CEO and founder Angie Conley in a news release. "Through the Texas Medical Center accelerator, we met Dr. Hany Samir who championed our upcoming stroke study."

Samir is a cardiac anesthesiologist at Houston Methodist. He lost his ability to work and perform simple daily functions after a stroke debilitated his left arm.

"I'm unable to practice the medicine I love. I want to hold my wife again with two hands and enjoy dinner with her, without having her cut my food. I want to have a cup of coffee without asking for help," says Samir in the release. "Regaining function in my arm will restore my life."

Pandata Tech receives Department of Defense contract

Photo courtesy of Pandata Tech

Houston-based ​Pandata Tech secured a contract with the United States Department of Defense from the Rapid Sustainment Office of the the United States Air Force last month. The Phase II contract will allow the company to work with Joint Base Elmendorf-Richardson in Alaska to develop a scalable data quality platform.

The access to data will aid in natural disasters, per the release. The goal of the contract would be for a Phase III contract and an opportunity to scale the technology into other branches of military. The company also had a Phase I contract signed in August before securing the Phase II in November.

"Pandata Tech's proprietary DQM software was built during a development partnership with one of the world's largest offshore drilling companies. Because the technology was tested and built with offshore drilling data, the shift to aircraft carriers would be smooth," explains Gustavo Sanchez, co-founder of Pandata Tech, in a news release.

Houston company receives Department of Energy funding

Photo via aerominepower.com

The U.S. Department of Energy's National Renewable Energy Laboratory — with funding from the DOE's Office of Energy Efficiency and Renewable Energy Wind Energy Technologies Office — selected a Houston company for its Competitiveness Improvement Project.

Westergaard Solutions, founded by Houstonian Carsten Westergaard, was named among the 2019 CIP Awardees. Among the company's assets is AeroMine, which competed in the most recent Houston cohort in MassChallenge Texas. The company "will implement an innovative building-integrated wind generation concept with no external moving parts, moving from a preliminary conceptual design to a pre-production prototype design that is ready for testing," according to the release.

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Houston engineers develop breakthrough device to advance spinal cord treatment

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A team of Rice University engineers has developed an implantable probe over a hundred times smaller than the width of a hair that aims to help develop better treatments for spinal cord disease and injury.

Detailed in a recent study published in Cell Reports, the probe or sensor, known as spinalNET, is used to explore how neurons in the spinal cord process sensation and control movement, according to a statement from Rice. The research was supported by the National Institutes of Health, Rice, the California-based Salk Institute for Biological Studies, and the philanthropic Mary K. Chapman Foundation based in Oklahoma.

The soft and flexible sensor was used to record neuronal activity in freely moving mice with high resolution for multiple days. Historically, tracking this level of activity has been difficult for researchers because the spinal cord and its neurons move so much during normal activity, according to the team.

“We developed a tiny sensor, spinalNET, that records the electrical activity of spinal neurons as the subject performs normal activity without any restraint,” Yu Wu, a research scientist at Rice and lead author of the study said in a statement. “Being able to extract such knowledge is a first but important step to develop cures for millions of people suffering from spinal cord diseases.”

The team says that before now the spinal cord has been considered a "black box." But the device has already helped the team uncover new findings about the body's rhythmic motor patterns, which drive walking, breathing and chewing.

Lan Luan (from left), Yu Wu, and Chong Xie are working on the breakthrough device. Photo by Jeff Fitlow/Rice University

"Some (spinal neurons) are strongly correlated with leg movement, but surprisingly, a lot of neurons have no obvious correlation with movement,” Wu said in the statement. “This indicates that the spinal circuit controlling rhythmic movement is more complicated than we thought.”

The team said they hope to explore these findings further and aim to use the technology for additional medical purposes.

“In addition to scientific insight, we believe that as the technology evolves, it has great potential as a medical device for people with spinal cord neurological disorders and injury,” Lan Luan, an associate professor of electrical and computer engineering at Rice and a corresponding author on the study, added in the statement.

Rice researchers have developed several implantable, minimally invasive devices to address health and mental health issues.

In the spring, the university announced that the United States Department of Defense had awarded a four-year, $7.8 million grant to the Texas Heart Institute and a Rice team led by co-investigator Yaxin Wang to continue to break ground on a novel left ventricular assist device (LVAD) that could be an alternative to current devices that prevent heart transplantation.

That same month, the university shared news that Professor Jacob Robinson had published findings on minimally invasive bioelectronics for treating psychiatric conditions. The 9-millimeter device can deliver precise and programmable stimulation to the brain to help treat depression, obsessive-compulsive disorder and post-traumatic stress disorder.

Houston clean hydrogen startup to pilot tech with O&G co.

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Gold H2, a Houston-based producer of clean hydrogen, is teaming up with a major U.S.-based oil and gas company as the first step in launching a 12-month series of pilot projects.

The tentative agreement with the unnamed oil and gas company kicks off the availability of the startup’s Black 2 Gold microbial technology. The technology underpins the startup’s biotech process for converting crude oil into proprietary Gold Hydrogen.

The cleantech startup plans to sign up several oil and gas companies for the pilot program. Gold H2 says it’s been in discussions with companies in North America, Latin America, India, Eastern Europe and the Middle East.

The pilot program is aimed at demonstrating how Gold H2’s technology can transform old oil wells into hydrogen-generating assets. Gold H2, a spinout of Houston-based biotech company Cemvita, says the technology is capable of producing hydrogen that’s cheaper and cleaner than ever before.

“This business model will reshape the traditional oil and gas industry landscape by further accelerating the clean energy transition and creating new economic opportunities in areas that were previously dismissed as unviable,” Gold H2 says in a news release.

The start of the Black 2 Gold demonstrations follows the recent hiring of oil and gas industry veteran Prabhdeep Singh Sekhon as CEO.

“With the proliferation of AI, growth of data centers, and a national boom in industrial manufacturing underway, affordable … carbon-free energy is more paramount than ever,” says Rayyan Islam, co-founder and general partner at venture capital firm 8090 Industries, an investor in Gold H2. “We’re investing in Gold H2, as we know they’ll play a pivotal role in unleashing a new dawn for energy abundance in partnership with the oil industry.”

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This article originally ran on EnergyCapital.

3 Houston innovators to know this week

who's who

Editor's note: Every week, I introduce you to a handful of Houston innovators to know recently making headlines with news of innovative technology, investment activity, and more. This week's batch includes an e-commerce startup founder, an industrial biologist, and a cellular scientist.

Omair Tariq, co-founder and CEO of Cart.com

Omair Tariq of Cart.com joins the Houston Innovators Podcast to share his confidence in Houston as the right place to scale his unicorn. Photo via Cart.com

Houston-based Cart.com, which operates a multichannel commerce platform, has secured $105 million in debt refinancing from investment manager BlackRock.

The debt refinancing follows a recent $25 million series C extension round, bringing Cart.com’s series C total to $85 million. The scaleup’s valuation now stands at $1.2 billion, making it one of the few $1 billion-plus “unicorns” in the Houston area.

Cart.com was co-founded by CEO Omair Tariq in October 2020. Read more.

Nádia Skorupa Parachin, vice president of industrial biotechnology at Cemvita

Nádia Skorupa Parachin joined Cemvita as vice president of industrial biotechnology. Photo courtesy of Cemvita

Houston-based biotech company Cemvita recently tapped two executives to help commercialize its sustainable fuel made from carbon waste.

Nádia Skorupa Parachin came aboard as vice president of industrial biotechnology, and Phil Garcia was promoted to vice president of commercialization.

Parachin most recently oversaw several projects at Boston-based biotech company Ginkjo Bioworks. She previously co-founded Brazilian biotech startup Integra Bioprocessos. Read more.

Han Xiao, associate professor of chemistry at Rice University

The funds were awarded to Han Xiao, a chemist at Rice University.

A Rice University chemist has landed a $2 million grant from the National Institute of Health for his work that aims to reprogram the genetic code and explore the role certain cells play in causing diseases like cancer and neurological disorders.

The funds were awarded to Han Xiao, the Norman Hackerman-Welch Young Investigator, associate professor of chemistry, from the NIH's Maximizing Investigators’ Research Award (MIRA) program, which supports medically focused laboratories. Xiao will use the five-year grant to advance his work on noncanonical amino acids.

“This innovative approach could revolutionize how we understand and control cellular functions,” Xiao said in the statement. Read more.

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