Beyoncé's dad is teaching a must-attend music business class. Photo courtesy of Mathew Knowles

Ever notice how Beyoncé's hair magically flows as if a fan follows her around everywhere she goes? That's not an accident. That attention to image micro-detail is preached by her father, Mathew Knowles, who created Destiny's Child and Music World Entertainment, the label and production company that boasts two of the top-selling superstars of the previous decade.

Now, music mogul Knowles is sharing his considerable knowledge in a new, 15-week virtual master class at the University of Houston's C.T. Bauer College of Business, running from January 25, 2021 to May 10, 2021. Knowles teases that there will be star-caliber guest instructors and appearances. The $3,000 virtual class is limited to 35 students but open to all who are able to register. (UH students and recent alumni can pay a discounted rate of $1,000.)

"I want to change the way we do things in the music business," Knowles says on a Zoom call. "Unfortunately, we have a very high failure rate [in the music industry]. Part of the reason we have this much failure is the business acumen of the team around the artists. It's not their talent. It's their team."

He hopes to change that with the class, dubbed "The Music Industry and the Digital Age." The class isn't specifically for aspiring artists, but aimed at those "behind the microphone," says Knowles. "Some people will be managers. Others will be independent record labels. Others will be in marketing. Artists will be part of this that would like to know business side of this."

Knowles is one of Houston's great success stories. Once a successful executive at Xerox, he recognized that his daughter, Beyoncé, had extraordinary music talent. He created Destiny's Child, held what he called "music bootcamps" at his home, and took night classes in entertainment management at Houston Community College.

From there, he founded his Music World Entertainment empire in 1992 in a Third Ward house, which mirrored his faraway mentor, Quincy Jones, who ensured every aspect of Motown's operation was all under one roof. Knowles would then become one of the most respected business minds in the music industry; he's taught at Texas Southern University; scored a PhD, and crafted management degrees for other schools. His empire boasts more than 100 award-winning albums and an MTV Video Music Award.

But that success, knowledge, and experience came with trial, error, and considerable money lost. "I wish someone had told me, 'Look, you need to really focus on getting the business acumens of the music industry down,'" he says.

That said, even with Destiny's dad's name attached, students shouldn't expect a get-famous-quick lottery ticket path to success with this class. "They think they can go from zero to a hero," Knowles says of that mindset. "This is not a microwave industry. I always say there is a price of admission to the music industry."

Sign us up. Memo to Professor Knowles: May we request guest lectures by Houston royalty Queen Bey and Lizzo?

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This article originally ran on CultureMap.

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Austin company to bring AI-powered school to The Woodlands

AI education

Austin-based Alpha School, which operates AI-powered private schools, is opening its first Houston-area location in The Woodlands.

The 8,000-square-foot school, scheduled to be ready for the 2026-27 academic year, initially will serve students in kindergarten through eighth grade. Alpha says the school will offer “open workshop spaces and innovative classrooms that support personalized instruction, core academics, leadership development, and real-world life skills.”

Alpha sets aside two hours each school day for the AI-driven, self-paced study of core subjects like math, reading and science. The rest of each school day consists of life-skills workshops focusing on topics such as leadership and financial literacy.

Alpha’s school in The Woodlands has begun accepting applications for the 2026-27 school year. Annual tuition costs $40,000.

“The Woodlands is one of the most dynamic, forward-thinking communities in Texas, and Alpha is proud to bring

an innovative educational model that complements its strong academic foundation,” says Rachel Goodlad, head

of expansion for Alpha.

Founded in 2014, Alpha School combines adaptive technology-driven instruction with immersive life-skills workshops. Its model emphasizes mastery-based learning in core subjects alongside development of communication, critical thinking, financial literacy and leadership skills. It operates more than 15 schools across the country.

Elsewhere in Texas, Alpha operates schools in Austin, Brownsville, Fort Worth and Plano. Alpha also operates 12 Texas Sports Academy campuses in Texas, including locations in Houston, Pearland and Richmond, along with a NextGen Academy esports school in Austin, a school for gifted students in Georgetown, and lower-cost Nova Academy campuses in Austin and Bastrop.

Alpha has fans and critics. While supporters tout students’ high achievement rates, detractors complain about the high tuition and the AI-influenced depersonalization of education.

“Students and our country need to be in relationship with other human beings,” Randi Weingarten, president of the American Federation of Teachers, a teachers union, tells The New York Times. “When you have a school that is strictly AI, it is violating that core precept of the human endeavor and of education.”

Alpha co-founder MacKenzie Price, a podcaster and social media influencer, doesn’t share Weingarten’s views.

“Parents and teachers: We need to embrace this change,” Price wrote after President Trump signed an executive order promoting AI in schools.

The Times notes that Alpha doesn’t employ AI as a tutor or a supplement. Rather, the newspaper says, AI is “the school’s primary educational driver to move students through academic content.”

Houston researcher secures $1.7M to develop drug for aggressive form of breast cancer

cancer research

A University of Houston researcher has joined a $3.2 million effort to develop a new drug designed to attack a cancer-driving protein commonly found in triple-negative breast cancer.

Triple-negative breast cancer (TNBC) is one of the most difficult-to-treat forms of cancer and accounts for 10 percent to 15 percent of all breast cancer cases. The disease gets its name because tumors associated with it test negative for estrogen receptors, progesterone receptors and excess HER2 protein, making it difficult to target. Due to this, TNBC is often treated with general chemotherapy, which can come with negative side effects and drug resistance, according to UH.

UH College of Pharmacy research associate professor Wei Wang is developing a drug that can target the disease more specifically. The drug will target MDM2, a protein often overproduced in TNBC that also contributes to faster tumor growth.

Wang is working on a team led by Wei Li, director of the University of Tennessee Health Science Center College of Pharmacy’s Drug Discovery Center. She has received $1.7 million to support the research.

Wang and UH professor of pharmacology and toxicology Ruiwen Zhang have discovered a compound that can break down MDM2. In early laboratory models, the compound has shown the ability to shrink tumors.

Wang and Zhang will focus on understanding how the treatment works and monitoring its effectiveness in models that closely mirror human disease.

“We will study how the drug targets MDM2 and evaluate the most promising drug candidates to determine effective dosing, understand how the drug behaves in the body, compare it with existing treatments and assess early safety,” Wang said in a news release.

Li’s team at the University of Tennessee will be working on the chemistry and drug design end of the project.

“This work could lead to an entirely new class of therapies for triple-negative breast cancer,” Li added in the release. “We’re hopeful that by directly removing the MDM2 protein from cancer cells, we can help more patients respond to treatment regardless of their tumor type.”