Here's what MassChallenge companies won big this year. Photo courtesy of MassChallenge

Nine startups that went through the 2021 Houston cohort for MassChallenge Texas have received cash prizes from the global accelerator.

Now in its 12th year, Boston-based MassChallenge awarded 39 equity-free cash and investment prizes to 36 early-stage companies from the 2021 virtual programs across Austin, Boston, Houston, and Rhode Island. The startups were recognized at a virtual showcase. Of the 229 companies to go through the program this year, about 70 of those were a part of the Houston cohort, which was announced in June, however none of the nine Houston cohort companies are based in Houston.

Here's which companies from the Houston program received awards:

  • AEROSENS, based in Miami, is a platform able to maximize aircraft cabin security and increase efficiency while reducing costs, using Bluetooth Low Energy sensors and the everyday smartphone or tablet. The company received a $25,000 Gold Award.
  • Analatom, based in Santa Clara, California, received the $10,000 FM Global Resilience Prize. The company has created an AI Deep Learning inspection technology automatically flag surface defects in images reducing maintenance costs improving inspection quality.
  • Astrileux Corporation, based in La Jolla, California, is accelerating manufacturing of next-gen ICs at 7 nm and smaller increasing power and performance in the era of zettabyte computing. The company scored one of the three top awards — a $100,000 Diamond Award.
  • Card Medic, based in the United Kingdom, received a $50,000 Platinum Award for its innovative digital technology designed to improve communication between healthcare staff and patients, across any barrier.
  • Exum Instruments, based in Denver, is combining high-performance tech with intuitive, seamless operations, Exum is solving materials characterization for a variety of industries. The company received a $25,000 Gold Award.
  • Grain4Grain, based in San Antonio, is using proprietary upcycling technology to turn byproducts from alcohol producers into low carb, high fiber flour alternatives at low cost. The company received a $25,000 Gold Award.
  • KNWN Technologies, based in DelRay Beach, received the Houston Angel Network Investment Prize as well as a $25,000 Gold Award. The technology provides a new level of identity validation for businesses to know and protect customer identity from enrollment through the life of the relationship.
  • Krtkl, based in San Francisco, is a new high-reliability edge-computing and artificial-intelligence solutions for robotics, sensing, and communications applications. The company received the ISSNL + CASIS Technology in Space Prize.
  • LucyDX, based in Middletown, Delaware, is preventing blindness in diabetics through early detection. The company received a $25,000 Gold Award.

Texas-based Ecliptic Capital will also give out its Investment Prize, but did not announce their winner at the showcase. The organization announced its full list of winners online and at the showcase.

"We designed our process to work with all founders especially those who may be overlooked or underestimated by traditional equity accelerators and investment models. These founders still benefit from and deserve access to accountability, expertise, and a network traditionally often made available only to venture-backed companies," says Siobhan Dullea, CEO of MassChallenge, in the press release. "The 229 startups from this year's cohort demonstrate just how much opportunity exists beyond the closed process of venture when we widen the lens. Congratulations to the winners."

MassChallenge Texas has named its 2021 cohorts — including 71 companies to accelerate in Houston. Photo courtesy of MassChallenge

MassChallenge Texas names the 71 startups that make up its latest Houston cohort

ready to grow

Five Houston-based startups have been accepted into MassChallenge's 50th startup accelerator.

Three of the local startups are part of the program's Houston cohort, and two are part of the Austin cohort. In all, 71 startups from around the world are participating in the new Houston cohort.

Aside from Houston and Austin, there are cohorts in Boston and Rhode Island. This year's MassChallenge class, announced June 28, comprises 229 startups from 20 countries.

The five Houston-based startups in MassChallenge's latest accelerator program are:

  • Church Space, an "Airbnb for churches" that enables churches to rent out space for worship, events, meetings, and ghost kitchens. It's part of the Houston cohort.
  • Every Shelter, which localizes response and relief efforts for global refugee crises. It's part of the Houston cohort.
  • Milkify, which freeze-dries breast milk, enabling mothers to carry it in a powdered form. It's part of the Houston cohort.
  • Javari, a music prediction and discovery platform. It's part of the Austin cohort.
  • Netnoids Rx Laboratories, which provides a platform called Spanio that lets individuals and companies test therapeutics. It's part of the Austin cohort.

"At the core of these early stage businesses is the entrepreneurial spirit of their founders. Entrepreneurial spirit is the unique blend of optimism, passion, and drive that gets founders and their businesses through the daunting early days," Jon Nordby, managing director of MassChallenge Texas, says in a news release.

Church Space, Every Shelter, and Milkify are among the 71 startups in the new Houston cohort. MassChallenge released the names of 69 of those companies. The two others are in stealth mode. Below are the names of the 69 publicly identified startups.

Energy / clean tech

  • Ener.com
  • SeebeckCell Technologies

General

  • Algdeha
  • Analatom
  • Astrileux
  • DeepCharge
  • Freshspire
  • Grain4Grain
  • Intelligent NanoFiber
  • Lepidext
  • Lodgeur
  • Milkify
  • NanoFlowX
  • Nature Knows
  • NjordFrey
  • ProFish Ghana
  • Solo
  • Stagetime

Health care / life sciences

  • AMF Medical
  • Arcascope
  • CardMedic
  • CaringWire
  • Exposphere Fitness
  • Galileo Innovations
  • Insu Health Design
  • Kismet Technologies
  • LucyDx
  • Newton Tech
  • Nightingale Caring Solutions
  • Nurlabs
  • Refined Imaging
  • Ronawk
  • SafetySit
  • SONOflammation
  • Tender Light Scientific
  • Uniphage
  • WestFace Medical

Social impact

  • Carta Digital
  • Every Shelter
  • Nile Agro Value Chain

Tech

  • Aerosens
  • Areanna AI
  • Church Space
  • CodeLn
  • Cybrik
  • Debtle
  • Edusko Africa
  • Exum Instruments
  • Fanorama Social Media
  • Glo3D.com
  • HintEd
  • Invento Robotics
  • KNWN Technologies
  • Krtki
  • Magos
  • Makeena
  • Manus Robotics
  • ModoScript
  • Notewardy
  • Nuw
  • Otomo
  • Owiwi
  • Patturn
  • Privoce
  • Third Ray
  • Tru-Spot Technologies
  • Yada.ai
  • Xena Intelligence
  • Xiggit

To be selected for the MassChallenge program, startups went through a two-round process that included more than 1,000 judges. During the program, participants will receive tools and advice to grow their businesses.

At the end of this year's program, startups will compete for equity-free cash prizes and grants adding up to $100,000. The prizes and grants will be awarded in October.

Attention Houston female founders — there are two new accelerator programs to have on your radars. Photo via Getty Images

Houston organizations announce two new female founder-focused programs

who runs the world?

A couple of Houston startup development organizations have recently announced programing and opportunities for female founders looking to advance their businesses.

Impact Hub Houston has announced that it has partnered up with Frost Bank to sponsor eight female founders to participate in Impact Hub's new Accelerate Membership Program. Applications are now open online and once the inaugural cohort is selected, they will receive the program for three months at no cost.

"At Impact Hub we believe the time to act is now. It's why we are excited to launch our new Accelerate Membership," says Maria Trindade, global network development director at Impact Hub Global, in a news release. "Its unique approach combines all the benefits of an enterprise support program with the flexibility that entrepreneurs need; plus its tailored nature makes this intervention highly accessible for entrepreneurs from diverse backgrounds who may not be able to dedicate full-time to their business idea."

Impact Hub Houston has also teamed up with MassChallenge for their own initiative supporting female founders in the Houston-Galveston region in partnership with Houston-based Workforce Solutions. The three organizations are collaborating to launch launch a bootcamp to support female founders in the greater Houston region.

"There is unprecedented growth in startup creation as a result of the pandemic and founders from all corners of the world are connecting in this virtual environment to build and scale amazing ideas," says Jon Nordby, managing director of MassChallenge Texas, in a news release. "With these new collaborations, we are also witnessing a massive gap in access to startup development resources. Our partnership with Workforce Solutions and Impact Hub Houston will help female founders build on their existing knowledge to become life-long innovators."

Applications for the bootcamp opened April 1 and will close at 5 pm on April 7 and are available online in both English and Spanish. The industry agnostic program will leverage MassChallenge's acceleration model and Impact Hub Houston's inclusive incubation expertise to accelerate female founders by connecting them with the resources they need to launch and scale high-impact businesses, according to the release.

"As a female founder myself, I'm incredibly excited about this opportunity to support and uplift more women entrepreneurs and women-led businesses in our region," says Grace Rodriguez, CEO and executive director of Impact Hub Houston, in the release. "By now, it's no secret that women, and especially women of color, are under-invested in; and this is our chance to change that by helping more women strengthen their businesses and prepare to seek funding."

Houston Exponential has announced the 38 finalists for the inaugural Listies Awards. Photo via Getty Images

Exclusive: HX names finalists for inaugural Houston innovation awards

the listies go to...

Ever wonder what Houston startups and innovators are the best of the best? Here's your chance to figure it out. The inaugural Listies awards program has named its finalists.

The Listies, brought to you by Houston Exponential in partnership with InnovationMap, will name the winning companies and people across 12 awards on November 20 at 3 pm at a virtual event as a part of Impact Hub's annual The Houston Innovation Summit (THIS). Click here to register for the free event.

Nominations were open until Friday, November 6, and then a group of judges made up of members of the Houston innovation ecosystem reviewed the submissions to settle on the finalists. Below, in alphabetical order, the 38 finalists are listed for each category.

DEI champion

  • Heath Butler
  • Maria Maso
  • Grace Rodriguez

Individual contributor

  • Michael Matthews
  • Slawek Omylski
  • Brad True

Mentor of the year

  • Keith Kreuer
  • Wade Pinder
  • Landi Spearman

Outstanding leadership

  • Stephanie Campbell
  • Grace Rodriguez
  • Roberta Schwartz

Corporate innovation

  • Chevron Technology Ventures
  • Houston Methodist
  • Shell Ventures

Investor of the year

  • CSL Capital Management
  • Golden Section VC (GSTVC)
  • Integr8d Capital

SDO superstar

  • MassChallenge Houston
  • Rice Alliance
  • TMCx

Welcome to Houston

  • Greentown Labs
  • TestCard
  • Win-Win

Civic engagement

  • Annapurna
  • Luminare
  • McMac Cx

COVID pivot/phoenix

  • Luminare
  • re:3D
  • sEATz

People choice

  • INK
  • Liongard
  • Luminare
  • re:3D
  • Topl

Soonicorn

  • GoExpedi
  • Liongard
  • Medical Informatics Corp.
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CultureMap Emails are Awesome

Intuitive Machines lands $600M satellite deal, NASA ‘spacecraft bus’ contract

space deals

Houston-based space infrastructure company Intuitive Machines has scored two astronomical deals.

The deals add to the company’s soaring success. As of June 30, Intuitive Machines had a record-high $1.8 billion backlog of orders, a $1.5 billion increase from the end of last year. The current backlog includes orders for more than 80 spacecraft.

The company, which went public in 2023, expects this year’s revenue to total $900 million to $1 billion. In the first half of 2026, Intuitive Machines generated nearly $393 million in revenue.

Intuitive Machines estimates its total available market is valued at more than $150 billion.

$600 million-plus deal represents ‘important milestone’

On Monday, Intuitive Machines said it picked up a $600 million-plus deal to develop three commercial satellites for an undisclosed customer over the course of about two years.

Intuitive Machines says it will design, manufacture, set up and support several spacecraft “for a critical communications infrastructure mission.”

Steve Altemus, the company’s CEO, says the deal represents “an important milestone for Intuitive Machines and reflects the confidence our customers place in our ability to deliver high-performance spacecraft for a broad range of mission needs.”

Company nails down NASA deal for ‘spacecraft bus’

A day after announcing the $600 million-plus deal, Intuitive Machines said it secured a new contract with NASA.

Intuitive Machines says NASA’s Jet Propulsion Laboratory in Southern California will use the company’s IM 300 “spacecraft bus” for an EAGLE-VSWIR Earth observation mission. The mission is scheduled to launch in 2028.

Aside from supplying the IM 300 bus, Intuitive Machines will carry out mission support services.

The low-Earth-orbit mission will be equipped with Intuitive Machines’ hyperspectral visible to shortwave infrared (VSWIR) instrument. This technology sees colors and details that aren’t visible to the human eye.

The instrument is “designed to perform surface biology and geology observations from Earth orbit while demonstrating technologies that could support future lunar and Mars exploration missions,” Intuitive Machines says.

Intuitive Machines builds mission-critical spacecraft, systems, and infrastructure for business and government customers. To date, the company has produced more than 300 spacecraft, delivered over 575 pounds of payload to the moon and launched about 100 satellites.

9 Houston-based companies make Fortune Global 500 list in 2026

Worldwide Rankings

Nine Houston companies landed on the 2026 Fortune Global 500 list, which ranks the world's largest corporations by revenue for the 2025 fiscal year.

Houston's showing on the list was led by energy companies, with Spring’s ExxonMobil claiming the top local spot. Here’s what Houston-area companies made the list, and where they ranked:

  • No. 15 ExxonMobil
  • No. 36 Chevron
  • No. 61 Phillip 66
  • No. 159 Sysco
  • No. 243 ConocoPhillips
  • No. 292 Enterprise Products Partners
  • No. 343 Plains GP Holdings
  • No. 460 SLB
  • No. 481 Hewlett Packard Enterprise

After 12 years as No.1, Arkansas-based Walmart was replaced this year by Seattle-based Amazon in the top spot for 2026. Amazon achieved this by bringing in $700 billion in revenue in 2025, representing a 12 percent increase from the previous year.

"Across global business, we see again and again that the leaders who are winning are those who embrace change,” Alyson Shontell, Fortune's editor in chief and chief content officer, said in a news release. "Amazon has topped the Fortune Global 500, knocking Walmart off its pedestal. The company has continually reinvented itself across new businesses and bold bets—including a $200 billion capital commitment, largely to building its capacity for AI and cloud computing, in this year alone."

The U.S. has 141 companies on the 2026 Fortune Global 500 list, which is the most of any country. Companies in America generated $15.5 trillion in aggregate revenues, a 6 percent increase from the previous year.

The number of women CEOs at Fortune Global 500 companies reached a record of 34 top leaders, who represented 6.8 percent of CEOs of companies on the list.

Technology was the standout growth industry on this year’s list, with 38 companies earning revenues that grew 20 percent to about $4 trillion in 2025, with profits climbing 36 percent to $835 billion. The financial sector accounted for the largest share of companies on the list again, with 123 companies in that sector. The energy sector claimed the No. 2 industry spot with 77 companies making the list.

In June, the Fortune 500 list was released, and Texas led the United States with 57 Fortune 500 companies headquartered in the state, generating $2.8 trillion in combined revenue.

Fast-growing Houston real estate startup surges to No. 7 on Inc. 5000

growth report

Houston-based Epique Realty has ridden the AI wave to rank among the Inc. 5000’s 10 fastest-growing private companies.

With three-year revenue growth of 23,210 percent, the AI-powered real estate brokerage appears at No. 7 on this year’s Inc. 5000 list. The 2026 list ranks private companies based on percentage revenue growth from 2022 to 2025.

Epique, founded in 2021, also ranks as the No. 1 fastest-growing company in Houston, No. 1 fastest-growing real estate company in the U.S., and No. 2 fastest-growing company in Texas.

Epique’s annual revenue surpasses $91 million

Between 2022 and 2025, the company’s annual revenue skyrocketed from $391,654 to more than $91.2 million. In 2025, the brokerage closed more than 23,000 deals and surpassed $7 billion in total sales, elevating Epique to the country’s 14th-largest real estate brokerage as measured by volume.

Epique’s network has more than 4,000 agents.

“To debut in the top 10 of the Inc. 5000 is absolute proof that when you relentlessly put agents first, exponential growth takes care of itself,” co-founder and CEO Joshua Miller said in a news release.

“We didn’t achieve this by following the industry playbook; we achieved this by burning it,” Miller added. “By fully funding our agents’ success through free health care, proprietary AI, and world-class leads, we’ve built a company where agents can finally thrive.”

The company’s other co-founders are Chris Miller, chief operating officer and vice president of expansion, and Janice Delci, chief financial officer.

Epique expands business to Canada, Mexico, Australia

The Millers and Delci have guided the company’s rapid expansion.

“Scaling our corporate support team to match [our] hyper-growth while seamlessly expanding across all 50 states and internationally to Canada, Australia, and Mexico takes an incomparable operational infrastructure,” Miller said.

“We have built an enterprise-grade technology ecosystem that allows us to absorb overhead and empower our agents at lightning speed,” he added. “This ranking validates that our disruptive model is working, and it is completely redefining the global industry standard.”

Epique launched its platform in 2023, touting itself as the industry’s first AI-powered brokerage. The startup’s platform provides AI tools for real estate agents to improve their marketing, streamline content creation, and boost engagement with clients and prospects.

Among Epique’s AI tools are:

  • ChatGPT for generation of property descriptions
  • AI-assisted creation of blog posts and agents’ bios
  • Production of Instagram quotes for social media marketing

“When we started Epique, we wanted to build a company that genuinely cared for its agents’ financial and physical well-being,” Delci says. “To see that vision translate into this level of historic record-breaking growth is a beautiful testament to the true power of radical generosity.”

Epique and fellow honorees will be recognized Oct. 14-16 at the 2026 Inc. 5000 Conference & Gala in Dallas.

Six other Houston-area companies land in top 250

Here are the six other Houston-area companies that claimed spots in the top 250 on the Inc. 5000 list. Each company name is followed by its ranking, headquarters city, and three-year growth rate.

  • No. 27 Empact Technologies, 8,275 percent
  • No. 60 Action1, 4,512 percent
  • No 75 Signs By G, 3,684 percent
  • No. 79 The ’Pause Life, 3,469 percent (Galveston)
  • No. 110 Turtlebox Audio, 2,576 percent
  • No. 178 Dahnani Private Equity Group, 1,904 percent (Stafford)

How did companies in Texas’ other major metros fare?

Here’s a breakdown of companies in the Austin, Dallas-Fort Worth, and San Antonio areas that made the top 250 on the Inc. 5000. Again, each company name is followed by its ranking, headquarters city, and three-year growth rate.

Austin (10 companies)

  • No. 9 Investment Watches, 15,741 percent
  • No. 72 Razor Metrics, 3,856 percent
  • No. 91 Autonomize AI, 2,921 percent
  • No. 102 Choose Your Horizon, 2,719 percent
  • No. 132 Wander Staffing, 2,296 percent
  • No. 144 Everyday Dose, 2,179 percent
  • No. 148 NetRise, 2,118 percent
  • No. 163 Nutrabound Labs, 1,999 percent (Bastrop)
  • No. 179 Steadily, 1,890 percent
  • No. 208 Tiny Health, 1,624 percent

Dallas-Fort Worth (11 companies)

  • No. 3 Yantran, 258,740 percent (Allen)
  • No. 12 Paek Management Group, 12,520 percent (Irving)
  • No. 82 Elite Robotics and Automation, 3,334 percent (Fort Worth)
  • No. 133 Outamation, 2,291 percent (Southlake)
  • No. 147 Red Creek Solutions, 2,119 percent (Frisco)
  • No. 155 JobTread Software, 2,071 percent (Dallas)
  • No. 164 DAX Eyewear, 1,977 percent (Nevada)
  • No. 186 Optimized Waste Removal, 1,830 percent (Fort Worth)
  • No. 204 Freight Flex, 1,642 percent (Denton)
  • No. 212 Maverick Power, 1,591 percent (McKinney)
  • No. 229 Innovative Life Sciences, 1,494 percent (McKinney)

San Antonio (one company)

  • No. 118 Hire With Near, 2,421 percent