Here's what MassChallenge companies won big this year. Photo courtesy of MassChallenge

Nine startups that went through the 2021 Houston cohort for MassChallenge Texas have received cash prizes from the global accelerator.

Now in its 12th year, Boston-based MassChallenge awarded 39 equity-free cash and investment prizes to 36 early-stage companies from the 2021 virtual programs across Austin, Boston, Houston, and Rhode Island. The startups were recognized at a virtual showcase. Of the 229 companies to go through the program this year, about 70 of those were a part of the Houston cohort, which was announced in June, however none of the nine Houston cohort companies are based in Houston.

Here's which companies from the Houston program received awards:

  • AEROSENS, based in Miami, is a platform able to maximize aircraft cabin security and increase efficiency while reducing costs, using Bluetooth Low Energy sensors and the everyday smartphone or tablet. The company received a $25,000 Gold Award.
  • Analatom, based in Santa Clara, California, received the $10,000 FM Global Resilience Prize. The company has created an AI Deep Learning inspection technology automatically flag surface defects in images reducing maintenance costs improving inspection quality.
  • Astrileux Corporation, based in La Jolla, California, is accelerating manufacturing of next-gen ICs at 7 nm and smaller increasing power and performance in the era of zettabyte computing. The company scored one of the three top awards — a $100,000 Diamond Award.
  • Card Medic, based in the United Kingdom, received a $50,000 Platinum Award for its innovative digital technology designed to improve communication between healthcare staff and patients, across any barrier.
  • Exum Instruments, based in Denver, is combining high-performance tech with intuitive, seamless operations, Exum is solving materials characterization for a variety of industries. The company received a $25,000 Gold Award.
  • Grain4Grain, based in San Antonio, is using proprietary upcycling technology to turn byproducts from alcohol producers into low carb, high fiber flour alternatives at low cost. The company received a $25,000 Gold Award.
  • KNWN Technologies, based in DelRay Beach, received the Houston Angel Network Investment Prize as well as a $25,000 Gold Award. The technology provides a new level of identity validation for businesses to know and protect customer identity from enrollment through the life of the relationship.
  • Krtkl, based in San Francisco, is a new high-reliability edge-computing and artificial-intelligence solutions for robotics, sensing, and communications applications. The company received the ISSNL + CASIS Technology in Space Prize.
  • LucyDX, based in Middletown, Delaware, is preventing blindness in diabetics through early detection. The company received a $25,000 Gold Award.

Texas-based Ecliptic Capital will also give out its Investment Prize, but did not announce their winner at the showcase. The organization announced its full list of winners online and at the showcase.

"We designed our process to work with all founders especially those who may be overlooked or underestimated by traditional equity accelerators and investment models. These founders still benefit from and deserve access to accountability, expertise, and a network traditionally often made available only to venture-backed companies," says Siobhan Dullea, CEO of MassChallenge, in the press release. "The 229 startups from this year's cohort demonstrate just how much opportunity exists beyond the closed process of venture when we widen the lens. Congratulations to the winners."

MassChallenge Texas has named its 2021 cohorts — including 71 companies to accelerate in Houston. Photo courtesy of MassChallenge

MassChallenge Texas names the 71 startups that make up its latest Houston cohort

ready to grow

Five Houston-based startups have been accepted into MassChallenge's 50th startup accelerator.

Three of the local startups are part of the program's Houston cohort, and two are part of the Austin cohort. In all, 71 startups from around the world are participating in the new Houston cohort.

Aside from Houston and Austin, there are cohorts in Boston and Rhode Island. This year's MassChallenge class, announced June 28, comprises 229 startups from 20 countries.

The five Houston-based startups in MassChallenge's latest accelerator program are:

  • Church Space, an "Airbnb for churches" that enables churches to rent out space for worship, events, meetings, and ghost kitchens. It's part of the Houston cohort.
  • Every Shelter, which localizes response and relief efforts for global refugee crises. It's part of the Houston cohort.
  • Milkify, which freeze-dries breast milk, enabling mothers to carry it in a powdered form. It's part of the Houston cohort.
  • Javari, a music prediction and discovery platform. It's part of the Austin cohort.
  • Netnoids Rx Laboratories, which provides a platform called Spanio that lets individuals and companies test therapeutics. It's part of the Austin cohort.

"At the core of these early stage businesses is the entrepreneurial spirit of their founders. Entrepreneurial spirit is the unique blend of optimism, passion, and drive that gets founders and their businesses through the daunting early days," Jon Nordby, managing director of MassChallenge Texas, says in a news release.

Church Space, Every Shelter, and Milkify are among the 71 startups in the new Houston cohort. MassChallenge released the names of 69 of those companies. The two others are in stealth mode. Below are the names of the 69 publicly identified startups.

Energy / clean tech

  • Ener.com
  • SeebeckCell Technologies

General

  • Algdeha
  • Analatom
  • Astrileux
  • DeepCharge
  • Freshspire
  • Grain4Grain
  • Intelligent NanoFiber
  • Lepidext
  • Lodgeur
  • Milkify
  • NanoFlowX
  • Nature Knows
  • NjordFrey
  • ProFish Ghana
  • Solo
  • Stagetime

Health care / life sciences

  • AMF Medical
  • Arcascope
  • CardMedic
  • CaringWire
  • Exposphere Fitness
  • Galileo Innovations
  • Insu Health Design
  • Kismet Technologies
  • LucyDx
  • Newton Tech
  • Nightingale Caring Solutions
  • Nurlabs
  • Refined Imaging
  • Ronawk
  • SafetySit
  • SONOflammation
  • Tender Light Scientific
  • Uniphage
  • WestFace Medical

Social impact

  • Carta Digital
  • Every Shelter
  • Nile Agro Value Chain

Tech

  • Aerosens
  • Areanna AI
  • Church Space
  • CodeLn
  • Cybrik
  • Debtle
  • Edusko Africa
  • Exum Instruments
  • Fanorama Social Media
  • Glo3D.com
  • HintEd
  • Invento Robotics
  • KNWN Technologies
  • Krtki
  • Magos
  • Makeena
  • Manus Robotics
  • ModoScript
  • Notewardy
  • Nuw
  • Otomo
  • Owiwi
  • Patturn
  • Privoce
  • Third Ray
  • Tru-Spot Technologies
  • Yada.ai
  • Xena Intelligence
  • Xiggit

To be selected for the MassChallenge program, startups went through a two-round process that included more than 1,000 judges. During the program, participants will receive tools and advice to grow their businesses.

At the end of this year's program, startups will compete for equity-free cash prizes and grants adding up to $100,000. The prizes and grants will be awarded in October.

Attention Houston female founders — there are two new accelerator programs to have on your radars. Photo via Getty Images

Houston organizations announce two new female founder-focused programs

who runs the world?

A couple of Houston startup development organizations have recently announced programing and opportunities for female founders looking to advance their businesses.

Impact Hub Houston has announced that it has partnered up with Frost Bank to sponsor eight female founders to participate in Impact Hub's new Accelerate Membership Program. Applications are now open online and once the inaugural cohort is selected, they will receive the program for three months at no cost.

"At Impact Hub we believe the time to act is now. It's why we are excited to launch our new Accelerate Membership," says Maria Trindade, global network development director at Impact Hub Global, in a news release. "Its unique approach combines all the benefits of an enterprise support program with the flexibility that entrepreneurs need; plus its tailored nature makes this intervention highly accessible for entrepreneurs from diverse backgrounds who may not be able to dedicate full-time to their business idea."

Impact Hub Houston has also teamed up with MassChallenge for their own initiative supporting female founders in the Houston-Galveston region in partnership with Houston-based Workforce Solutions. The three organizations are collaborating to launch launch a bootcamp to support female founders in the greater Houston region.

"There is unprecedented growth in startup creation as a result of the pandemic and founders from all corners of the world are connecting in this virtual environment to build and scale amazing ideas," says Jon Nordby, managing director of MassChallenge Texas, in a news release. "With these new collaborations, we are also witnessing a massive gap in access to startup development resources. Our partnership with Workforce Solutions and Impact Hub Houston will help female founders build on their existing knowledge to become life-long innovators."

Applications for the bootcamp opened April 1 and will close at 5 pm on April 7 and are available online in both English and Spanish. The industry agnostic program will leverage MassChallenge's acceleration model and Impact Hub Houston's inclusive incubation expertise to accelerate female founders by connecting them with the resources they need to launch and scale high-impact businesses, according to the release.

"As a female founder myself, I'm incredibly excited about this opportunity to support and uplift more women entrepreneurs and women-led businesses in our region," says Grace Rodriguez, CEO and executive director of Impact Hub Houston, in the release. "By now, it's no secret that women, and especially women of color, are under-invested in; and this is our chance to change that by helping more women strengthen their businesses and prepare to seek funding."

Houston Exponential has announced the 38 finalists for the inaugural Listies Awards. Photo via Getty Images

Exclusive: HX names finalists for inaugural Houston innovation awards

the listies go to...

Ever wonder what Houston startups and innovators are the best of the best? Here's your chance to figure it out. The inaugural Listies awards program has named its finalists.

The Listies, brought to you by Houston Exponential in partnership with InnovationMap, will name the winning companies and people across 12 awards on November 20 at 3 pm at a virtual event as a part of Impact Hub's annual The Houston Innovation Summit (THIS). Click here to register for the free event.

Nominations were open until Friday, November 6, and then a group of judges made up of members of the Houston innovation ecosystem reviewed the submissions to settle on the finalists. Below, in alphabetical order, the 38 finalists are listed for each category.

DEI champion

  • Heath Butler
  • Maria Maso
  • Grace Rodriguez

Individual contributor

  • Michael Matthews
  • Slawek Omylski
  • Brad True

Mentor of the year

  • Keith Kreuer
  • Wade Pinder
  • Landi Spearman

Outstanding leadership

  • Stephanie Campbell
  • Grace Rodriguez
  • Roberta Schwartz

Corporate innovation

  • Chevron Technology Ventures
  • Houston Methodist
  • Shell Ventures

Investor of the year

  • CSL Capital Management
  • Golden Section VC (GSTVC)
  • Integr8d Capital

SDO superstar

  • MassChallenge Houston
  • Rice Alliance
  • TMCx

Welcome to Houston

  • Greentown Labs
  • TestCard
  • Win-Win

Civic engagement

  • Annapurna
  • Luminare
  • McMac Cx

COVID pivot/phoenix

  • Luminare
  • re:3D
  • sEATz

People choice

  • INK
  • Liongard
  • Luminare
  • re:3D
  • Topl

Soonicorn

  • GoExpedi
  • Liongard
  • Medical Informatics Corp.
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CultureMap Emails are Awesome

Houston hailed as one of America's 10 best cities for startups

Startup Report

Houston's favorable economic climate is enticing new opportunities for entrepreneurship and growth, and now the city is being hailed as the 7th-best U.S. city for starting a business.

The recognition comes in CommercialCafe's recent "Best Cities for Startups" report, published December 10. The study analyzed large U.S. cities across two population categories – cities with more than 1 million residents and cities with populations between 500,000 and 1 million residents. The report analyzed relevant metrics such as office or coworking costs, Kickstarter funding success, startup density, and survival rates, among others.

Across the biggest U.S. cities with over a million residents, Phoenix, Arizona landed on top as the No. 1 best place to start a new business.

The report's findings revealed 10.6 percent of all businesses in Houston are startups that have been active for less than a year. These new businesses have a survival rate of 64.5 percent, meaning just under two-thirds of all startups in the city will still be running up to five years after they were first established.

Over the last five years, the number of new businesses established in Houston has grown nearly 15 percent. CommercialCafe said new businesses in cities with high startup growth rates tend to "attract top talent" which can eventually lead to securing "vital funding for expansion."

Independent professionals – also known as freelancers – are another crucial resource for new businesses that may need "specialized services" for a fixed amount of time, the report said. Houston's freelance workforce has grown about 9 percent from 2019-2023, and the analysis found there were 97,295 freelancers working in Houston in 2023, compared to 89,528 in 2019.

"Generally, cities in the South and Southwest have experienced strong growth during the surveyed period, in contrast to California cities like Los Angeles and San Diego, where the share of freelancers and gig workers has either stagnated or slightly declined," the report said.

Houston boasts the second-cheapest office space rent nationally, the report found. The average asking price for a 1,000-square-foot workspace (for five employees) in the city added up to $27,124 annually. For startups that want greater flexibility for their workers, the annual cost for a coworking space for the same number of employees in Houston came out to $13,200, which is the fourth-most affordable rate in the U.S.

Other Texas cities with attractive economic environments for startups

Texas, as a whole, is one of the strongest states for starting a new business. Other than Houston, San Antonio (No. 2), Dallas (No. 3), and Fort Worth (No. 4) were also recognized among the top 10 best places to start a business in the category of U.S. cities with more than a million residents.

Austin topped a separate ranking of best cities to start a business with 500,000 to 1 million residents.

"Specifically, the Texas capital was the frontrunner for indicators that looked at the overall share of startups within the local economy, as well as growth rates in five years (2019 to 2023)," the report said. "On top of that, Austin also topped the rankings for its percentage of college-educated residents and its consulting firms, which provide vital support for burgeoning enterprises."

The top 10 best cities to start a new business are:

  • No. 1 – Phoenix, Arizona
  • No. 2 – San Antonio, Texas
  • No. 3 – Dallas, Texas
  • No. 4 – Fort Worth, Texas
  • No. 5 – Jacksonville, Florida
  • No. 6 – San Diego, California
  • No. 7 – Houston, Texas
  • No. 8 – Philadelphia, Pennsylvania
  • No. 9 – Chicago, Illinois
  • No. 10 – Los Angeles, California
---

This article originally appeared on CultureMap.com.

Top Houston space news of 2025 soars with NASA deals, lunar missions

Year in Review

Editor's note: As 2025 comes to a close, we're looking back at the stories that defined Houston innovation this year. The space tech sector soared with companies landing huge NASA contracts and furthering their lunar missions. Here are the 10 biggest Houston space tech stories of the year:

Houston native picked for 2025 class of NASA astronaut candidates

Houston native Anna Menon, posing below the first A in “NASA,” is one of 10 new NASA astronaut candidates. Photo courtesy NASA.

NASA has selected 10 new astronaut candidates, including one whose hometown is Houston, for its 2025 training class. The candidates will undergo nearly two years of training before they can assume flight assignments.

Intuitive Machines lands $9.8M to complete orbital transfer vehicle

Intuitive Machines expects to begin manufacturing and flight integration on its orbital transfer vehicle as soon as 2026. Photo courtesy Intuitive Machines.

Houston-based Intuitive Machines, which rang the NASDAQ opening bell July 31, secured a $9.8 million Phase Two government contract for its orbital transfer vehicle. The contract will push the project through its Critical Design Review phase, which is the final engineering milestone before manufacturing can begin.

Houston tech company tapped by NASA for near space initiative

Intuitive Machines is among four companies awarded contracts for NASA’s Near Space Network. Photo via intuitivemachines.com

In January, Intuitive Machines nailed down a NASA deal to expand the agency’s communications network for spacecraft. Additionally, NASA completed the first round of “human in the loop” testing for Intuitive Machines’ Moon RACER lunar terrain vehicle at the agency’s Johnson Space Center. RACER (Reusable Autonomous Crewed Exploration Rover) is one of three commercially developed unpressurized lunar terrain vehicles being considered for NASA’s Artemis lunar initiative.

Texas Space Commission doles out $5.8 million to Houston companies

Axiom Space and FluxWorks are the latest Houston-area companies to receive funding from the Texas Space Commission. Photo via Getty Images.

Two Houston-area companies landed more than $5.8 million in funding from the Texas Space Commission. The commission granted up to $5.5 million to Houston-based Axiom Space and up to $347,196 to Conroe-based FluxWorks in June 2025. The two-year-old commission previously awarded $95.3 million to 14 projects. A little over $34 million remains in the commission-managed Space Exploration and Aeronautics Research Fund.

Houston company awarded $2.5B NASA contract to support astronaut health and space missions

NASA has awarded KBR a five-year, $2.5 billion Human Health and Performance Contract. Photo courtesy NASA.

Houston-based technology and energy solution company KBR was awarded a $2.5 billion NASA contract to support astronaut health and reduce risks during spaceflight missions. Under the terms of the Human Health and Performance Contract 2, KBR will provide support services for several programs, including the Human Research Program, International Space Station Program, Commercial Crew Program, Artemis campaign and others. This will include ensuring crew health, safety, and performance; occupational health services and risk mitigation research for future flights.

Houston engineering firm lands $400M NASA contract

Bastion Technologies has been tapped to provide safety and mission services for NASA's Marshall Space Flight Center in Alabama. Photo via nasa.gov.

NASA granted Houston-based Bastion Technologies Inc. the Safety and Mission Assurance II (SMAS II) award with a maximum potential value of $400 million. The award stipulates that the engineering and technical services company provide safety and mission services for the agency’s Marshall Space Flight Center in Huntsville, Alabama.

Houston startups win NASA funding for space tech projects

Houston startups were recently named among the nearly 300 recipients that received a portion of $44.85 million from NASA to develop space technology. Photo via NASA/Ben Smegelsky

Three Houston startups were granted awards from NASA in July 2025 to develop new technologies for the space agency. The companies were among nearly 300 recipients that received a total agency investment of $44.85 million through the Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) Phase I grant programs.

Texas Republicans are pushing to move NASA headquarters to Houston

Here's why Texas Republicans think NASA's headquarters should move to Texas in 2028. File photo.

Two federal lawmakers from Texas spearheaded a campaign to relocate NASA’s headquarters from Washington, D.C., to the Johnson Space Center in Houston’s Clear Lake area. Houston faces competition on this front, though, as lawmakers from two other states are also vying for this NASA prize. With NASA’s headquarters lease in D.C. set to end in 2028, U.S. Sen. Ted Cruz, a Texas Republican, and U.S. Rep. Brian Babin, a Republican whose congressional district includes the Johnson Space Center, wrote a letter to President Trump touting the Houston area as a prime location for NASA’s headquarters.

Intuitive Machines to acquire NASA-certified deep space navigation company

Intuitive Machines will acquire Kinetx, which marks its entry into the precision navigation and flight dynamics segment of deep space operations. Photo via Getty Images.

In August 2025, Intuitive Machines agreed to buy Tempe, Arizona-based aerospace company KinetX for an undisclosed amount. The deal is expected to close by the end of this year. KinetX specializes in deep space navigation, systems engineering, ground software and constellation mission design. It’s the only company certified by NASA for deep space navigation. KinetX’s navigation software has supported both of Intuitive Machines’ lunar missions.

Axiom Space launches semiconductor and astronaut training initiatives

Axiom Space chief astronaut Michael López-Alegría (left) trains with Axiom’s new “Project Astronaut,” Emiliano Ventura. Photo courtesy of Axiom Space.

In fall 2025, Axiom Space, a Houston-based commercial spaceflight and space infrastructure company, launched initiatives in two very different spheres — semiconductors and astronaut training.

Paraplegic engineer becomes first wheelchair user to blast into space

Space News

A paraplegic engineer from Germany blasted off on a dream-come-true rocket ride with five other passengers Saturday, December 20, leaving her wheelchair behind to float in space while beholding Earth from on high.

Severely injured in a mountain bike accident seven years ago, Michaela Benthaus became the first wheelchair user in space, launching from West Texas with Jeff Bezos’ company Blue Origin. She was accompanied by a retired SpaceX executive also born in Germany, Hans Koenigsmann, who helped organize and, along with Blue Origin, sponsored her trip. Their ticket prices were not divulged.

An ecstatic Benthaus said she laughed all the way up — the capsule soared more than 65 miles (105 kilometers) — and tried to turn upside down once in space.

“It was the coolest experience,” she said shortly after landing.

The 10-minute space-skimming flight required only minor adjustments to accommodate Benthaus, according to the company. That’s because the autonomous New Shepard capsule was designed with accessibility in mind, “making it more accessible to a wider range of people than traditional spaceflight,” said Blue Origin’s Jake Mills, an engineer who trained the crew and assisted them on launch day.

Among Blue Origin’s previous space tourists: those with limited mobility and impaired sight or hearing, and a pair of 90-year-olds.

For Benthaus, Blue Origin added a patient transfer board so she could scoot between the capsule’s hatch and her seat. The recovery team also unrolled a carpet on the desert floor following touchdown, providing immediate access to her wheelchair, which she left behind at liftoff. She practiced in advance, with Koenigsmann taking part with the design and testing. An elevator was already in place at the launch pad to ascend the seven stories to the capsule perched atop the rocket.

Benthaus, 33, part of the European Space Agency’s graduate trainee program in the Netherlands, experienced snippets of weightlessness during a parabolic airplane flight out of Houston in 2022. Less than two years later, she took part in a two-week simulated space mission in Poland.

“I never really thought that going on a spaceflight would be a real option for me because even as like a super healthy person, it’s like so competitive, right?” she told The Associated Press ahead of the flight.

Her accident dashed whatever hope she had. “There is like no history of people with disabilities flying to space," she said.

When Koenigsmann approached her last year about the possibility of flying on Blue Origin and experiencing more than three minutes of weightlessness on a space hop, Benthaus thought there might be a misunderstanding. But there wasn't, and she immediately signed on.

It’s a private mission for Benthaus with no involvement by ESA, which this year cleared reserve astronaut John McFall, an amputee, for a future flight to the International Space Station. The former British Paralympian lost his right leg in a motorcycle accident when he was a teenager.

An injured spinal cord means Benthaus can’t walk at all, unlike McFall who uses a prosthetic leg and could evacuate a space capsule in an emergency at touchdown by himself. Koenigsmann was designated before flight as her emergency helper; he and Mills lifted her out of the capsule and down the short flight of steps at flight’s end.

“You should never give up on your dreams, right?” Benthaus urged following touchdown.

Benthaus was adamant about doing as much as she could by herself. Her goal is to make not only space accessible to the disabled, but to improve accessibility on Earth too.

While getting lots of positive feedback within “my space bubble,” she said outsiders aren't always as inclusive.

“I really hope it’s opening up for people like me, like I hope I’m only the start," she said.

Besides Koenigsmann, Benthaus shared the ride with business executives and investors, and a computer scientist. They raised Blue Origin’s list of space travelers to 86.

Bezos, the billionaire founder of Amazon, created Blue Origin in 2000 and launched on its first passenger spaceflight in 2021. The company has since delivered spacecraft to orbit from Cape Canaveral, Florida, using the bigger and more powerful New Glenn rocket, and is working to send landers to the moon.