The local community has raised some concerns about Rice Management Company's Ion project's effect on the Third Ward. Courtesy of Rice University

The city of Houston has been buzzing about Rice Management Company's Ion Innovation Hub — a 270,000-square-foot coworking and innovation hub project expected to deliver in 2021 — but there's one group isn't so thrilled with the plans: The Third Ward community.

In a public community meeting on November 12, community members gathered at the Wesley AME Church to plan a Community Benefits Agreement that would legally bind The Innovation District's development team and the Rice Management Company to move forward with the local residents' indicated best interests. According to the Houston Coalition for Equitable Development without Displacement, a newly formed group to work on the CBA, it would be the first of its kind in Houston.

The coalition is supported by Third Ward is Home Civic Club, the Emancipation Economic Development Council, the Texas Coalition of Black Democrats - Harris County, and the Houston Society for Change.

Gabriella Rowe, executive director of The Ion, presented the project's plans to the crowd, recognizing that innovation ecosystems across the country have issues with diversity.

"When you look around the tech ecosystems in the United States today, there are a couple things that stand out," Rowe says. "First and foremost is that they are extremely white and extremely male."

But since Houston is still developing its innovation infrastructure, Rowe says, the city has more opportunities to take the lessons learned from these other ecosystems and be more proactive about including diverse efforts.

One of the things The Ion is planning to incorporate to engage the community is a free coworking space — the only free coworking space in Houston, Rowe says. The Ion plans also include two public parks and community events, and both will be free and open to the public.

The Ion promises to bring free coworking, park space, and events to the area. Courtesy of Rice University

After the presentation, the estimated 150 community members in the crowd had the opportunity to address Rowe. While one local resident expressed concern with the non-inclusive verbiage The Ion is using — describing the area as "Midtown" over the pre-gentrification descriptor of Third Ward — other concerns surrounded the lack of diversity of the decision makers on the project.

"For me, that's where we need to start, which is in diversity," says Rowe, who mentions she has diversity among her programming team. "I look to all of you to come to get included in our team as we're growing."

Another concern that was raised was the job opportunities on the construction site itself. While Rowe didn't mention any specific job opportunities in construction, she did say she had been asked by the Rice Management Company to tap local artists to design the fences surrounding the site.

The meeting pivoted toward a discussion about the CBA and the importance the agreement would have moving forward. Assata Richards, founder of Sankofa Research Institute and local activist, and Mary Claire Neal, a Rice University student and leader of the Students for a Just and Equitable Innovation Corridor, and Carl Davis, chair of the Houston Society for Change and a representative of the church, have teamed up to move forward with the agreement.

Texas Appleseed, a group of volunteer lawyers, has agreed to help create and enforce the agreement, and Jeffrey Lowe, associate professor in the department of urban planning and environmental policy at Texas Southern University, has also advised the organizations.

"We've been told what's going to happen, but there's no binding agreement to make sure that it's going to happen," Richards says. "Those are just nice wishlists."

Moreover, the initiatives that have been suggested, enforceable or not, aren't enough, Richards adds, again stressing the importance of the CBA.

"We're going to be smarter this time. We're going to work with the people who have the power and make the decisions," Richards says. "You're doing all this development and come and tell me that you want art outside the building? We're talking millions of dollars of construction."

While the terms of the CBA are still in the works, some of the requests mentioned in the meeting include jobs, preservation of communities of color, affordable housing initiatives, access to affordable groceries, and opportunities for minority and African American-owned businesses.

The Ion Innovation Hub Proposed Site PlanThe Ion Innovation Hub Proposed Site Plan was included in notes pre-released ahead of the Houston Planning Commission's November 14 meeting. Photo via HPC

Neal proceeded with a presentation of actionable ways students and community members can get involved and make their voices heard. Her presentation included new concerns following the release of the master plan of The Innovation District, which the Houston Chronicle released earlier this week. The plans included a parking area that will be the next construction project following The Ion. The variance request is headed to the planning commission on Thursday.

"That's a two-day turnaround and it's the first opportunity for us to do something," Neal says. The group is intending to at least acquire a delay in the variance request moving forward.

The meeting wrapped up with a call to action for local residents as well as students. Since The Ion will include local academic institutions, student and alumni input is crucial.

"We want you to hold up and pause and think carefully on how this development is going to benefit and affect the community," Richards says.

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Houston-area lab grows with focus on mobile diagnostics and predictive medicine

mobile medicine

When it comes to healthcare, access can be a matter of life and death. And for patients in skilled nursing facilities, assisted living or even their own homes, the ability to get timely diagnostic testing is not just a convenience, it’s a necessity.

That’s the problem Principle Health Systems (PHS) set out to solve.

Founded in 2016 in Clear Lake, Texas, PHS began as a conventional laboratory but quickly pivoted to mobile diagnostics, offering everything from core blood work and genetic testing to advanced imaging like ultrasounds, echocardiograms, and X-rays.

“We were approached by a group in a local skilled nursing facility to provide services, and we determined pretty quickly there was a massive need in this area,” says James Dieter, founder, chairman and CEO of PHS. “Turnaround time is imperative. These facilities have an incredibly sick population, and of course, they lack mobility to get the care that they need.”

What makes PHS unique is not only what they do, but where they do it. While they operate one of the largest labs serving skilled nursing facilities in the state, their mobile teams go wherever patients are, whether that’s a nursing home, a private residence or even a correctional facility.

Diagnostics, Dieter says, are at the heart of medical decision-making.

“Seventy to 80 percent of all medical decisions are made from diagnostic results in lab and imaging,” he says. “The diagnostic drives the doctor’s or the provider’s next move. When we recognized a massive slowdown in lab results, we had to innovate to do it faster.”

Innovation at PHS isn’t just about speed; it’s about accessibility and precision.

Chris Light, COO, explains: “For stat testing, we use bedside point-of-care instruments. Our phlebotomists take those into the facilities, test at the bedside, and get results within minutes, rather than waiting days for results to come back from a core lab.”

Scaling a mobile operation across multiple states isn’t simple, but PHS has expanded into nine states, including Texas, Oklahoma, Kansas, Missouri and Arizona. Their model relies on licensed mobile phlebotomists, X-ray technologists and sonographers, all trained to provide high-level care outside traditional hospital settings.

The financial impact for patients is significant. Instead of ambulance rides and ER visits costing thousands, PHS services often cost just a fraction, sometimes only tens or hundreds of dollars.

“Traditionally, without mobile diagnostics, the patient would be loaded into a transportation vehicle, typically an ambulance, and taken to a hospital,” Dieter says. “Our approach is a fraction of the cost but brings care directly to the patients.”

The company has also embraced predictive and personalized medicine, offering genetic tests that guide medication decisions and laboratory tests that predict cognitive decline from conditions like Alzheimer's and Parkinson’s.

“We actively look for complementary services to improve patient outcomes,” Dieter says. “Precision medicine and predictive testing have been a great value-add for our providers.”

Looking to the future, PHS sees mobile healthcare as part of a larger trend toward home-based care.

“There’s an aging population that still lives at home with caretakers,” Dieter explains. “We go into the home every day, whether it’s an apartment, a standalone home, or assisted living. The goal is to meet patients where they are and reduce the need for hospitalization.”

Light highlighted another layer of innovation: predictive guidance.

“We host a lot of data, and labs and imaging drive most treatment decisions,” Light says. “We’re exploring how to deploy diagnostics immediately based on results, eliminating hours of delay and keeping patients healthier longer.”

Ultimately, innovation at PHS isn’t just about technology; it’s about equity.

“There’s an 11-year life expectancy gap between major metro areas and rural Texas,” Dieter says. “Our innovation has been leveling the field, so everyone has access to high-quality diagnostics and care, regardless of where they live.”

Aegis Aerospace appoints Houston space leader as new president

moving up

Houston-based Aegis Aerospace's current chief strategy officer, Matt Ondler, will take on the additional role of president on Jan. 1. Ondler will succeed Bill Hollister, who is retiring.

“Matt's vision, experience, and understanding of our evolving markets position us to build on our foundation and pursue new frontiers,” Stephanie Murphy, CEO of Aegis Aerospace, said in a news release.

Hollister guided Aegis Aerospace through expansion and innovation in his three years as president, and will continue to serve in the role of chief technology officer (CTO) for six months and focus on the company's technical and intellectual property frameworks.

"Bill has played an instrumental role in shaping the success and growth of our company, and his contributions leave an indelible mark on both our culture and our achievements," Murphy said in a news release.

Ondler has a background in space hardware development and strategic leadership in government and commercial sectors. Ondler founded subsea robots and software company Houston Mechatronics, Inc., now known as Nauticus Robotics, and also served as president, CTO and CSO during a five-year tenure at Axiom Space. He held various roles in his 25 years at NASA and was also named to the Texas Aerospace Research and Space Economy Consortium Executive Committee last year.

"I am confident that with Matt at the helm as president and Bill supporting us as CTO, we will continue to build on our strong foundation and further elevate our impact in the space industry," Murphy said in a news release. "Matt's vision, experience, and understanding of our evolving markets position us to build on our foundation and pursue new frontiers."

Rice University launches new center to study roots of Alzheimer’s and Parkinson’s

neuro research

Rice University launched its new Amyloid Mechanism and Disease Center last month, which aims to uncover the molecular origins of Alzheimer’s, Parkinson’s and other amyloid-related diseases.

The center will bring together Rice faculty in chemistry, biophysics, cell biology and biochemistry to study how protein aggregates called amyloids form, spread and harm brain cells. It will serve as the neuroscience branch of the Rice Brain Institute, which was also recently established.

The team will work to ultimately increase its understanding of amyloid processes and will collaborate with the Texas Medical Center to turn lab discoveries into real progress for patients. It will hold its launch event on Jan. 21, 2026, and hopes to eventually be a launchpad for future external research funding.

The new hub will be led by Pernilla Wittung-Stafshed, a Rice biophysicist and the Charles W. Duncan Jr.-Welch Chair in Chemistry.

“To make a real difference, we have to go all the way and find a cure,” Wittung-Stafshede said in a news release. “At Rice, with the Amyloid Mechanism and Disease Center as a catalyst, we have the people and ideas to open new doors toward solutions.”

Wittung-Stafshede, who was recruited to Rice through a Cancer Prevention and Research Institute of Texas grant this summer, has led pioneering work on how metal-binding proteins impact neurodegenerative disorders, including Alzheimer’s and Parkinson’s diseases. Her most recent study, published in Advanced Science, suggests a new way of understanding how amyloids may harm cells and consume the brain’s energy molecule, ATP.

According to Alzheimer’s Disease International, neurodegenerative disease cases could reach around 78 million by 2030 and 139 million by 2050. Wittung-Stafshede’s father died of dementia several years ago.

“This is close to my heart,” Wittung-Stafshede added in the news release. “Neurodegenerative diseases such as dementia, Alzheimer’s and Parkinson’s are on the rise as people live longer, and age is the largest risk factor. It affects everyone.”