The 11 executives now will move on to national Entrepreneur Of The Year program. National winners will be named in November. Photos courtesy

Eleven Houston-based executives have been crowned regional winners in the Entrepreneur Of The Year program, run by professional services firm EY.

The 11 executives now will move on to national Entrepreneur Of The Year program. National winners will be named in November.

“Every year, we are completely blown away by the accomplishments of our Entrepreneur Of The Year Regional Award winners, and 2023 is no different,” AJ Jordan, director of the Entrepreneur Of The Year program for EY Americas, says in a news release. “They are change-makers and champions of business and community, and we are so proud to be honoring them. We can’t wait to see how these leaders will continue to improve lives and disrupt industries.”

Here are the 11 local winners from the program’s Gulf South region.

Steve Altemus, president and CEO of Intuitive Machines

Intuitive Machines, founded in 2013, is a publicly traded space exploration company. The company’s upcoming mission will send the first U.S. spacecraft to the moon since 1972 as well as the first-ever commercial lunar lander. Its Nova-C spacecraft will carry commercial and NASA payloads.

Earlier this year, a joint venture led by Intuitive Machines nabbed a contract valued at up to $719 million for work on NASA’s Joint Polar Satellite System. The company, which went public in February 2023, forecasts revenue of $174 million to $268 million this year.

“Steve’s visionary mindset and ability to assemble and inspire a talented team have been instrumental in our collective success,” the company says in a statement about the Entrepreneur Of The Year award. “He consistently fosters a culture of excellence, empowering our diverse group of engineers, scientists, and visionaries to pioneer groundbreaking solutions and deliver outstanding results.”

Gaurab Chakrabarti, co-founder and CEO of Solugen, and Sean Hunt, co-founder and CTO

Solugen, founded in 2016, makes and distributes specialty chemicals derived from feedstock. The startup is reportedly valued at more than $2 billion. To date, Solugen has raised $642.2 million, according to Crunchbase.

In naming Solugen one of the most innovative companies of 2022, Fast Company noted that the carbon-negative process embraced by Solugen and the startup’s “ability to sell flexible amounts of chemicals to companies looking to lower their own footprint have helped the company make inroads in a traditionally slow-moving industry.”

Daryl Dudum and Matthew Hadda, founders and co-CEOs of Specialty1 Partners

Specialty1 Partners, which launched in 2019, supplies business services to dental surgery practices. These services include HR, recruiting, payroll, accounting, operations, marketing, business development, compliance, IT, and legal.

In 2022, Specialty1 Partners appeared at No. 72 on the Inc. 5000 list with two-year revenue growth of 2,921 percent.

“Supporting our partners and helping them grow while continuing to build partnerships with industry-leading, innovative surgical specialists is what we focus on every day,” Dudum says in a 2022 news release. “It’s not just about growing our network — we are committed to helping our partner practices grow and succeed on their terms.”

Ludmila Golovine, president and CEO of MasterWord Services

MasterWord Services offers translation and interpretation in more than 400 languages for customers such as energy, health care, and tech companies. The woman-owned business was founded in 1993.

“I’m grateful to our exceptional team and to each of our translators and interpreters who every day live our mission of connecting people across language and culture,” Golovine says in a news release about the Entrepreneur Of The Year honor.

Roger Jenkins, president and CEO of Murphy Oil

Murphy Oil is involved in oil and natural gas exploration and production primarily onshore in the U.S. and Canada, and offshore along the Gulf of Mexico. The publicly traded Fortune 1000 company, founded in 1944, racked up revenue of nearly $4 billion in 2022.

“Over the years, the company has grown and evolved to become a leading independent energy company, with strategic assets around the world,” Murphy says on its website. “All the while, we have remained true to our mission — to challenge the norm, tap into our strong legacy, and use our foresight and financial discipline to deliver inspired energy solutions.

Mohammad Millwala, founder and CEO of DM Clinical Research

DM Clinical Research, founded in 2006, runs 13 sites for clinical trials. Its areas of specialty include vaccines, internal medicine, pediatrics, gastrointestinal, psychiatry, and women’s health.

“DM Clinical Research is in a period of rapid growth with multiple new study sites added over the last two years in addition to the quadrupling of our staff to over 500 employees,” Millwala says in a January 2023 news release. “We expect this transformational growth trajectory to continue for the foreseeable future, on the road to becoming the leading independent clinical research network in the nation.”

Mark Walker, co-founder, chairman and CEO of Direct Digital Holdings, and Keith Smith, co-founder and president

Publicly traded Direct Digital Holdings owns three operating companies that offer online platforms for advertising. Three years after its founding in 2018, the company became the ninth Black-owned business to go public in the U.S.

The company posted revenue of $88 million in 2022, up 131 percent from the previous year.

“Direct Digital Holdings’ success is rooted in the hard work and commitment we have long seen in taking advantage of advertising opportunities targeting underserved communities and [that] markets often overlook,” Smith says in a news release about the Entrepreneur Of The Year award.

Omair Tariq, co-founder and CEO of Cart.com

While technically headquartered in Austin, Houston-funded Cart.com's co-founder and CEO, Omair Tariq, also was a Gulf South winner in the Entrepreneur Of The Year program.

The e-commerce company moved its headquarters from Houston to Austin in 2021. However, Tariq remains in Houston. In May 2023, Tariq delivered the commencement address to MBA recipients from Rice University’s Jones Graduate School of Business, where he earned his MBA.

Cart.com, founded in 2020, offers software and services to thousands of online merchants. To date, the pre-IPO company has raised $421 million in funding, according to Crunchbase.

“We want to be the commerce-enablement infrastructure for the largest brands in the world,” Tariq told the Insider news website in 2022.

This week's roundup of Houston innovators includes Mark Walker of Direct Digital Holdings, Will Womble of Umbrage, and Steve Altemus of Intuitive Machines. Photos courtesy

3 Houston innovators to know this week

who's who

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — from adtech to aerospace — recently making headlines in Houston innovation.

Mark Walker, CEO, co-founder and chairman of Direct Digital Holdings

This month, Mark Walker is celebrating his company's one year anniversary of going public — only the ninth Black-founded business to accomplish this feat on a U.S. stock exchange. Photo courtesy

Houston-based Direct Digital Holdings, an adtech platform, is celebrating one year after its IPO. Co-Founder Mark Walker shares on the Houston Innovators Platform how he took this experience in tech, advertising, and media to create his company's platform.

He also shared the story of how Direct Digital went public. Walker says the decision to IPO made the most sense for his company — though it wasn't an easy process. Direct Digital is only the ninth company founded by a Black entrepreneur to go public on a US stock exchange.

"If you think the process is hard — it actually is," Walker says on the journey to IPO. "We were a privately held company, and we knew we had a good growth trajectory and we looked a couple different options. We decided to go public in a very traditional way." Read more.

Steve Altemus, co-founder, president, and CEO of Intuitive Machines

Intuitive Machines listed on Nasdaq on February 14. Photo via intuitivemachines.com

Intuitive Machines, a space tech company based in Southeast Houston, announced that it has completed the transaction to merge with Inflection Point Acquisition Corp., a special purpose acquisition company traded on Nasdaq.

“We are excited to begin this new chapter as a publicly traded company,” says Steve Altemus, co-founder, president, and CEO of Intuitive Machines, in a news release. “Intuitive Machines is in a leading position to replace footprints with a foothold in the development of lunar space. With our launch into the public sphere through Inflection Point, we have reached new heights financially and opened the doors for even greater exploration and innovation for the progress of humanity.”

The transaction, which was originally announced in September, was approved by Inflection Point’s shareholders in a general meeting on February 8. As a result of the deal, the company will receive around $55 million of committed capital from an affiliate of its sponsor and company founders, the release states. Read more.

Will Womble, founder and CEO of Umbrage

Umbrage, a Houston-based developer of enterprise software, has been acquired. Photo via umbrage.com

Umbrage, founded in 2019, is proving once again that Space City is a software hub. Earlier this month, Founder Will Womble announced that Umbrage has been acquired by Bain & Company.

Umbrage creates custom software for companies by partnering with an internal technology team that makes the products. It’s a “teach a man to fish” method that has brought the company great success in creating software such as Shell’s TapUp app.

Bain & Company works with clients in 64 cities across 39 countries, meaning the global consultancy is positioned to bring Umbrage worldwide.

"Alongside Bain, we can deliver enhanced end-to-end solutions that will position our clients for success and to adapt during waves of disruptive emerging technologies," says CEO Womble in the release. Read more.

This month, Mark Walker is celebrating his company's one year anniversary of going public — only the ninth Black-founded business to accomplish this feat on a U.S. stock exchange. Photo courtesy

Houston founder shares how he's using tech to make digital media more effective and equitable

houston innovators podcast episode 173

After working in both sides of the advertising world, Mark Walker thought he could reimagine a platform that would be more efficient and equitable.

Walker co-founded his company, Direct Digital Holdings, an adtech platform, after serving in several roles — from an early hire at Houston digital media startup Questia to business development director at NRG Energy and COO of EBONY Media. He shares on the Houston Innovators Platform how he took this experience in tech, advertising, and media to create his company's platform.

"NRG Energy gave me a top-down view of the value chain, and Ebony gave me a bottoms-up view of the value chain of how media is purchased," Walker says on the show. "At Direct Digital Holdings, we help companies buy and sell media — and we leverage technology to do it. It's really the culmination of both of those experiences."

With over 30,000 publishers on its platform, Direct Digital makes it easier for its core customers — middle market companies looking to buy into the digital media ecosystem — to tap into these opportunities without the tech know-how they might otherwise need. Walker explains that at EBONY, he saw how small to midsize publications — especially the multicultural ones — were being left out on the ad selling side of the equation. The Direct Digital platform bridges the gap on each end.

Founded in 2018 in partnership with Keith Smith, who went through similar professional experiences, Direct Digital went public exactly one year ago after growing the company through strategic M&A activity. Walker says the decision to IPO made the most sense for his company — though it wasn't an easy process. Direct Digital is only the ninth company founded by a Black entrepreneur to go public on a US stock exchange.

"If you think the process is hard — it actually is," Walker says on the journey to IPO. "We were a privately held company, and we knew we had a good growth trajectory and we looked a couple different options. We decided to go public in a very traditional way."

Walker explains there were some risks involved, but the co-founders ultimately decided to shy away from adding in investors who might not have the same ideas for the company's future.

Direct Digital has been a Houston company from the star — despite the city not being home to a booming adtech ecosystem. Instead, Houston — with its collection of Fortune 500 companies and rich diversity — has allowed the business to stand out.

"If you look at and reflect on how our company has been built — from our board of directors to our leadership and management team — we're a majority minority organization all the way across the board," Walker says. "Diversity is very important to us. It's the lifeblood of our business — especially because we're serving publishers in those communities in big way. And moreso, we think you get the best product, thoughts, and ideas from a diverse workforce, and Houston fits right into that mold for us."

Walker shares more about his company's future, advice on IPO, and what all he's watching in adtech — from AI to streaming — on the podcast. Listen to the interview below — or wherever you stream your podcasts — and subscribe for weekly episodes.


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Autonomous truck company with Houston routes goes public

on a roll

Kodiak Robotics, a provider of AI-powered autonomous vehicle technology, has gone public through a SPAC merger and has rebranded as Kodiak AI. The company operates trucking routes to and from Houston, which has served as a launchpad for the business.

Privately held Kodiak, founded in 2018, merged with a special purpose acquisition company — publicly held Ares Acquisition Corp. II — to form Kodiak AI, whose stock now trades on the Nasdaq market.

In September, Mountain View, California-based Kodiak and New York City-based Ares disclosed a $145 million PIPE (private investment in public equity) investment from institutional investors to support the business combo. Since announcing the SPAC deal, more than $220 million has been raised for the new Kodiak.

“We believe these additional investments underscore our investors’ confidence in the value proposition of Kodiak’s safe and commercially deployed autonomous technology,” Don Burnette, founder and CEO of Kodiak, said in a news release.

“We look forward to leading the advancement of the commercial trucking and public sector industries,” he added, “and delivering on the exciting value creation opportunities ahead to the benefit of customers and shareholders.”

Last December, Kodiak debuted a facility near George Bush Intercontinental/Houston Airport for loading and loading driverless trucks. Transportation and logistics company Ryder operates the “truckport” for Ryder.

The facility serves freight routes to and from Houston, Dallas and Oklahoma City. Kodiak’s trucks currently operate with or without drivers. Kodiak’s inaugural route launched in 2024 between Houston and Dallas.

One of the companies using Kodiak’s technology is Austin-based Atlas Energy Solutions, which owns and operates four driverless trucks equipped with Kodiak’s driver-as-a-service technology. The trucks pick up fracking sand from Atlas’ Dune Express, a 42-mile conveyor system that carries sand from Atlas’ mine to sites near customers’ oil wells in the Permian Basin.

Altogether, Atlas has ordered 100 trucks that will run on Kodiak’s autonomous technology in an effort to automate Atlas’ supply chain.

Rice University scientists invent new algorithm to fight Alzheimer's

A Seismic Breakthrough

A new breakthrough from researchers at Rice University could unlock the genetic components that determine several human diseases such as Parkinson's and Alzheimer's.

Alzheimer's disease affected 57 million people worldwide in 2021, and cases in the United States are expected to double in the next couple of decades. Despite its prevalence and widespread attention of the condition, the full mechanisms are still poorly understood. One hurdle has been identifying which brain cells are linked to the disease.

For years, it was thought that the cells most linked with Alzheimer's pathology via DNA evidence were microglia, infection-fighting cells in the brain. However, this did not match with actual studies of Alzheimer's patients' brains. It's the memory-making cells in the human brain that are implicated in the pathology.

To prove this link, researchers at Rice, alongside Boston University, developed a computational algorithm called “Single-cell Expression Integration System for Mapping Genetically Implicated Cell Types," or SEISMIC. It allows researchers to zero in on specific neurons linked to Alzheimer's, the first of its kind. Qiliang Lai, a Rice doctoral student and the lead author of a paper on the discovery published in Nature Communications, believes that this is an important step in the fight against Alzheimer's.

“As we age, some brain cells naturally slow down, but in dementia — a memory-loss disease — specific brain cells actually die and can’t be replaced,” said Lai. “The fact that it is memory-making brain cells dying and not infection-fighting brain cells raises this confusing puzzle where DNA evidence and brain evidence don’t match up.”

Studying Alzheimer's has been hampered by the limitations of computational analysis. Genome-wide association studies (GWAS) and single-cell RNA sequencing (scRNA-seq) map small differences in the DNA of Alzheimer's patients. The genetic signal in these studies would often over-emphasize the presence of infection fighting cells, essentially making the activity of those cells too "loud" statistically to identify other factors. Combined with greater specificity in brain regional activity, SEISMIC reduces the data chatter to grant a clearer picture of the genetic component of Alzheimer's.

“We built our SEISMIC algorithm to analyze genetic information and match it precisely to specific types of brain cells,” Lai said. “This enables us to create a more detailed picture of which cell types are affected by which genetic programs.”

Though the algorithm is not in and of itself likely to lead to a cure or treatment for Alzheimer's any time soon, the researchers say that SEISMIC is already performing significantly better than existing tools at identifying important disease-relevant cellular signals more clearly.

“We think this work could help reconcile some contradicting patterns in the data pertaining to Alzheimer’s research,” said Vicky Yao, assistant professor of computer science and a member of the Ken Kennedy Institute at Rice. “Beyond that, the method will likely be broadly valuable to help us better understand which cell types are relevant in different complex diseases.”

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This article originally appeared on CultureMap.com.

5 incubators and accelerators fueling the growth of Houston startups

meet the finalists

Houston is home to numerous accelerators and incubators that support founders in pushing their innovative startups and technologies forward.

As part of our 2025 Houston Innovation Awards, the new Incubator/Accelerator of the Year category honors a local incubator or accelerator that is championing and fueling the growth of Houston startups.

Five incubators and accelerators have been named finalists for the 2025 award. They support startups ranging from hard-tech companies to digital health startups.

Read more about these organizations below. Then join us at the Houston Innovation Awards on Nov. 13 at Greentown Labs, when the winner will be unveiled.

Get your tickets now on sale for this exclusive event celebrating Houston Innovation.

Activate

Hard tech incubator Activate supports scientists in "the outset of their entrepreneurial journey." The Houston hub was introduced last year, and joins others in Boston, New York, and Berkley, California—where Activate is headquartered. It named its second Houston cohort this summer.

This year, the incubator grew to include its largest number of concurrent supported fellows, with 88 companies currently being supported nationally. In total, Activate has supported 296 fellows who have created 236 companies. Those companies have raised over $4 billion in follow-on funding, according to Activate. In Houston, it has supported several Innovation Awards finalists, including Solidec, Bairitone Health and Deep Anchor Solutions. It is led locally by Houston Managing Director Jeremy Pitts.

EnergyTech Nexus

Cleantech startup hub EnergyTech Nexus' mission is to accelerate the energy transition by connecting founders, investors and industrial stakeholders and helping to develop transformative companies, known as "thunderlizards."

The hub was founded in 2023 by CEO Jason Ethier, Juliana Garaizar and Nada Ahmed. It has supported startups including Capwell Services, Resollant, Syzygy Plasmonics, Hertha Metals, EarthEn Energy and Solidec—many of which are current or past Innovation Awards finalists. This year Energy Tech Nexus launched its COPILOT Accelerator, powered by Wells Fargo Innovation Incubator (IN²) at the National Renewable Energy Laboratory (NREL). COPILOT partners with Browning the Green Space, a nonprofit that promotes diversity, equity and inclusion (DEI) in the clean energy and climatech sectors. Energy Tech Nexus also launched its Liftoff fundraising program, its Investor Program, and a "strategic ecosystem partnership" with Greentown Labs.

Greentown Labs

Climatetech incubator Greentown Labs offers its community resources and a network to climate and energy innovation startups looking to grow. The collaborative community offers members state-of-the-art prototyping labs, business resources and access to investors and corporate partners. The co-located incubator was first launched in Boston in 2011 before opening in Houston in 2021.

Greentown has seen major changes and activity this year. In February, Greentown announced Georgina Campbell Flatter as its new CEO, along with a new Board of Directors. In July, it announced Lawson Gow as its Head of Houston, a "dedicated role to champion the success of Greentown Houston’s startups and lead Greentown’s next chapter of impact in the region," according to Greentown. It has since announced numerous new partnerships, including those with Energy Tech Nexus, Los Angeles-based software development firm Nominal, to launch the new Industrial Center of Excellence; and Houston-based Shoreless, to launch an AI lab onsite. Greentown Houston has supported 175 startups since its launch in 2021, with 45 joining in the last two years. Those startups include the likes of Hertha Metals, RepAir Carbon, Solidec, Eclipse Energy (formerly GoldH2) and many others.

Healthtech Accelerator (TMCi)

The Healthtech Accelerator, formerly TMCx, focuses on clinical partnerships to improve healthcare delivery and outcomes. Emerging digital health and medical device startups that join the accelerator are connected with a network of TMC hospitals and seasoned advisors that will prepare them for clinical validation, funding and deployment.

The Healthtech Accelerator is part of Texas Medical Center Innovation, which also offers the TMCi Accelerator for Cancer Therapeutics. The Healthtech Accelerator named its 19th, and latest, cohort of 11 companies last month.

Impact Hub Houston

Impact Hub Houston supports early-stage ventures at various stages of development through innovative programs that address pressing societal issues. The nonprofit organization supports social impact startups through mentorship, connections and training opportunities.

There are more than 110 Impact Hubs globally with 24,000-plus members spanning 69 countries, making it one of the world’s largest communities for accelerating entrepreneurial solutions toward the United Nations' Sustainable Development Goals (SDGs).

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The Houston Innovation Awards program is sponsored by Houston City College Northwest, Houston Powder Coaters, FLIGHT by Yuengling, and more to be announced soon. For sponsorship opportunities, please contact sales@innovationmap.com.