Detractors are suspicious of the anonymity that comes with blockchain technology. Supporters say it's exactly the point. Photo via David McBee/Pexels

Interest in cryptocurrencies reignited during the pandemic, driven in part by trillions of dollars in stimulus money that left many investors with “free money” to put to work. And while bitcoin recently tumbled nearly 55 percent from its peak, it remains the most valuable crypto asset in the world, with a market capitalization of around $589 billion. Its investors argue that it’s still a safer bet than stocks during this period of economic upheaval.

A renewed interest in cryptocurrencies — digital currencies that rely on blockchain technology, in which transactions are verified and records maintained by a decentralized system that uses cryptography — is widespread. Large corporations like Tesla, Mass Mutual and KPMG Canada have announced plans to hold cryptocurrency assets in treasury or accept them as payment. Meanwhile, major financial institutions are offering customers more digital asset investment options. Twelve years after bitcoin’s birth, mainstream investors are honing in on the currency, too.

In the midst of this market fascination, a fundamental question still remains. What exactly is cryptocurrency, and why should we care? And what about other industry buzzwords, like blockchain, decentralized exchanges or non-fungible tokens (NFTs)? Are they all just fads that will fade away?

Some have called cryptocurrency a Ponzi scheme, a tool for illicit activities, or a short-term fascination that will be irrelevant in a few years. It’s an understandable mindset, since there’s no intrinsic value in cryptocurrencies — not unlike the U.S. dollar after it stopped being backed by gold in the 1970s. But it’s also a shortsighted one. Blockchain technology, which allows users to exchange information on a secure digital ledger, is extremely useful because it automates contractual arrangements through computer programming.

I’m a firm believer that cryptocurrencies and the blockchain technology that underpins them are here to stay, and understanding how this technology has transformed our environment, and how it will continue to evolve, is critical to succeeding in business.

First steps

Bitcoin took the first major steps towards a truly electronic cash system in 2008, in the midst of one of the worst financial collapses of all time. Governments worldwide were bailing out financial institutions that had been deemed “too big to fail.” Perceptions of economic inequality spurred movements such as Occupy Wall Street, which was fueled by a distrust in banks.

Bitcoin, on the other hand, wasn’t created by a trusted source — in fact, no one knows exactly who invented it. In a 2008 white paper, “Bitcoin: A Peer-to-Peer Electronic Cash System,” Satoshi Nakamoto — the pseudonymous individual presumed to have developed bitcoin — described the currency as a way to securely facilitate financial transactions between parties without having to involve a central intermediary. No longer would people have to put their trust in the large financial institutions that failed them during the financial crisis.

Detractors find the lack of a central authority with blockchain worrisome, but proponents say it’s exactly the point: You no longer have to trust the person or institution you’re dealing with. You only have to trust the algorithms that run the program — and presumably an algorithm will never run off with your money.

Instead, blockchain enables a cooperative of members to run the shared network ledger required to keep track of a currency’s credits and debits. No one can shut down the system so long as a group of computers anywhere in the world is able to connect to the internet and run bitcoin’s software.

Because of bitcoin, today we can uniquely own digital assets and transfer them with the certainty that people can’t spend the same cryptocurrency twice. The transactions that bitcoin-like applications make possible are registered in permanent and immutable digital records for all to see in a common ledger.

By enabling fast and easily verifiable transactions, blockchain technology is also streamlining business operations in banking, supply chains, sustainability, healthcare and even voting. Development in these sectors and others is continuing at an intense pace. Annual global funding of blockchain projects now runs in the billions of dollars. From 2020 to 2021 alone, it jumped from several billion to nearly $30 billion.

Second generation

Since bitcoin’s arrival, we’ve seen a second, more sophisticated generation of cryptocurrencies evolve, with Ethereum as their flagship. Ethereum has its own programming language, enabling users to write and automate self-executing smart contracts, allowing for the creation of tokens for a specific use. For example, imagine that when Uber was founded, it had created an Uber token, and only people who owned Uber tokens could use the rideshare service. Tokens currently power thousands of decentralized applications that give people more privacy and control in a variety of areas, such as internet browsing, financial services, gaming and data storage, among others.

Some critiques of cryptocurrency remain. One growing concern is that cryptocurrencies require a significant amount of energy to run their networks, leading to higher transaction costs, energy waste and limited scalability. Newer cryptocurrencies are attempting to find ways to verify transactions that require less energy.

Some people also worry about ongoing volatility in cryptocurrency markets. A third generation of cryptocurrencies has emerged to address this concern: so-called “stablecoins,” which are pegged to a government-issued currency, a commodity, assets, or basket of assets. For some, stablecoins are serving as an onramp into the world of crypto from the world of traditional finance.

Before a new technology becomes part of everyday life, we often see a long period of development, improvement and consumer adoption. Cryptocurrency and blockchain markets are still in this early development stage, but they’re also moving quickly into the mainstream. The total market capitalization of cryptocurrencies late last year briefly reached the $3 trillion mark, or roughly 15 percent of the U.S. GDP, and there’s been more than $100 billion locked into decentralized finance applications.

Large companies like IBM, Amazon and Bank of America are leading the way by tapping into blockchain technology in their daily business activities. It won’t be long until this market, previously characterized by speculation and wild volatility, will be transformed into a stable infrastructure framework. But companies need to get up to speed on the industry now. Those that commit to doing so will be the ones that thrive.


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This article originally ran on Rice Business Wisdom and was written by Manolo Sánchez, an adjunct professor of operations management at the Jones Graduate School of Business at Rice University.

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Meta to bring $115 million AI data center training initiative to Houston

ai workforce

Meta and Associated Builders and Contractors have entered into a partnership to invest $115 million in training programs for the construction of AI data centers, with a portion of the project launching in Houston.

The companies announced June 8 that they would open America’s Workforce Academies at ABC chapter training centers in Houston; Indianapolis; Baton Rouge, Louisiana; and Columbus, Ohio.

The academies will offer career readiness and safety training, plus five weeks of hands-on education. Participants who complete the program will be granted a job offer from contractors working on Meta projects.

“The AI revolution is bringing change but also historic opportunities,” Dina Powell McCormick, Meta president and vice-chairman, said in a news release. “Skilled workers electrified rural America one pole at a time. They manned the factories that built the arsenal that won World War II. Now a new generation will pour the foundations and lay the fiber that secures American strength in this new age.”

Overall, the Meta and ABC aim for the academies to build a more sustainable pipeline of skilled construction workers and ensure safety and job readiness for the surging number of data center projects underway.

“This new program is an innovative talent solution that is a critical part of addressing the construction industry’s ongoing workforce shortage and creates an accelerated, new-entrant strategy for job seekers ... The sustained demand for data center construction technicians means the industry needs an all-of-the-above approach to address this shortage and grow the construction talent pool,” Michael Bellaman, ABC president and CEO, added in the release.

In Texas, Meta, the parent company of Facebook and Instagram, has launched or broken ground on data centers in El Paso, Fort Worth and Temple. The company announced in March that it planned to grow its El Paso Data center by 1 gigawatt, representing more than a $10 billion investment.

Apart from Meta, Texas has attracted data center development to power other giants like Google and Amazon in recent years. In turn, Texas has been predicted to become the biggest data center market. Commercial real estate services provider JLL reported this spring that the state could topple Northern Virginia as the world’s largest data-center market by 2030. Similarly, CBRE predicted that Houston's data center capacity could double by 2028. Read more here.

New Houston biotech co. lands $30M for pulmonary fibrosis drug

drug money

Most of us can claim a scar or two on our bodies. But when scarring develops inside the body, it’s known as a fibrotic disorder. A freshly launched Houston company, Oorja Bio Inc., is working on a treatment that can help to repair cells and reduce the damage wrought by the growth of fibrotic tissue in patients.

Late last month, Oorja Bio hit the scene with a pair of big announcements. Not only has the company raised a $30 million Series A thanks to founding investor California-based Westlake BioPartners, but it has also already paved the way for a Phase 2 study to take place this year.

Oorja Bio received Investigational New Drug (IND) clearance from the U.S. Food and Drug Administration (FDA), allowing the company to test its treatment in patients with idiopathic pulmonary fibrosis (IPF), a scarring of the lung tissue. IPF affects more than 150,000 adults in the United States and can result in a range of symptoms from shortness of breath to organ failure and death as it progresses.

Oorja Bio’s lead drug candidate, ORJ-001, was shown in a Phase 1 in-human trial to demonstrate “therapeutically relevant exposure and favorable tolerability” in 64 healthy adult volunteers in whom it was administered daily or weekly, according to a news release. Pre-clinical studies of ORJ-001 showed durable target tissue engagement and biomarker activity in bleomycin-induced lung fibrosis.

Administered subcutaneously, ORJ-001 is intended to improve and even restore function in cells that can reduce the signaling that causes IPF. It stops advancement of IPF and also allows for tissue repair. Currently available treatments for the disease can slow the development of IPF down, but do not address the declining lung function that’s inherent in its progression.

“The clinical and preclinical results from our studies to date give us confidence that ORJ-001 represents a novel treatment approach with the potential to repair and reverse fibrosis and modify disease progression in IPF,” Dr. Janethe Pena, CMO of Oorja Bio, said in the release.

“Our team is energized to deliver on our goal of redefining the future of fibrotic diseases, beginning with ORJ-001,” CEO and founder Sujay Kango added. “As we advance ORJ-001 in the clinic, we are embracing the paradigm shift in our biological understanding of IPF pathology that aligns with the central role of the alveolar epithelium. ORJ-001 was designed with this biology in mind and may provide, for the first time, a therapeutic intervention that repairs and reverses fibrosis and promotes disease modification.”

Most patients live only three to five years following their IPF diagnosis. Soon, ORJ-001 and Oorja Bio could give them a fighting chance.

Axiom Space tops $525M in oversubscribed round, announces Swiss subsidiary

funding boost

Axiom Space tacked on an additional $175 million to a previously announced capital raise, bringing the oversubscribed round to a total of more than $525 million.

Axiom shared in February that it had secured $350 million in a financing round led by Type One Ventures and Qatar Investment Authority. In the latest release from the company, Axiom reports that Japan-based MUFG Bank Ltd. joined the round as a new investor, in addition to continued participation from existing backers.

The funding will go toward developing the company's commercial space station, known as Axiom Station, and the production of its Axiom Extravehicular Mobility Unit (AxEMU) under its NASA spacesuit contract.

“Investor interest in this round outpaced what we set out to raise, which speaks to the moment we’re in,” Jonathan Cirtain, CEO and president of Axiom Space, said in the news release. “Our partners see what is possible in low-Earth orbit, and they see who is positioned to lead it.”

Axiom announced last month that it planned to open a Japanese subsidiary July 1. Earlier this week, it also shared plans to establish Axiom Space Switzerland, a wholly owned subsidiary based in Lucerne that is also expected to begin operations this summer.

The Switzerland subsidiary aims to establish Axiom's presence in Europe and help it partner with the European Space Agency and other space organizations and companies on the continent.

“Europe is a founding leader in the creation of the commercial space economy, and Switzerland is uniquely positioned to convene the government agencies, research institutions, and industrial entities that will shape its next decade,” Cirtain added in a separate release. “Axiom Space Switzerland facilitates the scaling of development and deployment of the infrastructure that will succeed the International Space Station.”