Detractors are suspicious of the anonymity that comes with blockchain technology. Supporters say it's exactly the point. Photo via David McBee/Pexels

Interest in cryptocurrencies reignited during the pandemic, driven in part by trillions of dollars in stimulus money that left many investors with “free money” to put to work. And while bitcoin recently tumbled nearly 55 percent from its peak, it remains the most valuable crypto asset in the world, with a market capitalization of around $589 billion. Its investors argue that it’s still a safer bet than stocks during this period of economic upheaval.

A renewed interest in cryptocurrencies — digital currencies that rely on blockchain technology, in which transactions are verified and records maintained by a decentralized system that uses cryptography — is widespread. Large corporations like Tesla, Mass Mutual and KPMG Canada have announced plans to hold cryptocurrency assets in treasury or accept them as payment. Meanwhile, major financial institutions are offering customers more digital asset investment options. Twelve years after bitcoin’s birth, mainstream investors are honing in on the currency, too.

In the midst of this market fascination, a fundamental question still remains. What exactly is cryptocurrency, and why should we care? And what about other industry buzzwords, like blockchain, decentralized exchanges or non-fungible tokens (NFTs)? Are they all just fads that will fade away?

Some have called cryptocurrency a Ponzi scheme, a tool for illicit activities, or a short-term fascination that will be irrelevant in a few years. It’s an understandable mindset, since there’s no intrinsic value in cryptocurrencies — not unlike the U.S. dollar after it stopped being backed by gold in the 1970s. But it’s also a shortsighted one. Blockchain technology, which allows users to exchange information on a secure digital ledger, is extremely useful because it automates contractual arrangements through computer programming.

I’m a firm believer that cryptocurrencies and the blockchain technology that underpins them are here to stay, and understanding how this technology has transformed our environment, and how it will continue to evolve, is critical to succeeding in business.

First steps

Bitcoin took the first major steps towards a truly electronic cash system in 2008, in the midst of one of the worst financial collapses of all time. Governments worldwide were bailing out financial institutions that had been deemed “too big to fail.” Perceptions of economic inequality spurred movements such as Occupy Wall Street, which was fueled by a distrust in banks.

Bitcoin, on the other hand, wasn’t created by a trusted source — in fact, no one knows exactly who invented it. In a 2008 white paper, “Bitcoin: A Peer-to-Peer Electronic Cash System,” Satoshi Nakamoto — the pseudonymous individual presumed to have developed bitcoin — described the currency as a way to securely facilitate financial transactions between parties without having to involve a central intermediary. No longer would people have to put their trust in the large financial institutions that failed them during the financial crisis.

Detractors find the lack of a central authority with blockchain worrisome, but proponents say it’s exactly the point: You no longer have to trust the person or institution you’re dealing with. You only have to trust the algorithms that run the program — and presumably an algorithm will never run off with your money.

Instead, blockchain enables a cooperative of members to run the shared network ledger required to keep track of a currency’s credits and debits. No one can shut down the system so long as a group of computers anywhere in the world is able to connect to the internet and run bitcoin’s software.

Because of bitcoin, today we can uniquely own digital assets and transfer them with the certainty that people can’t spend the same cryptocurrency twice. The transactions that bitcoin-like applications make possible are registered in permanent and immutable digital records for all to see in a common ledger.

By enabling fast and easily verifiable transactions, blockchain technology is also streamlining business operations in banking, supply chains, sustainability, healthcare and even voting. Development in these sectors and others is continuing at an intense pace. Annual global funding of blockchain projects now runs in the billions of dollars. From 2020 to 2021 alone, it jumped from several billion to nearly $30 billion.

Second generation

Since bitcoin’s arrival, we’ve seen a second, more sophisticated generation of cryptocurrencies evolve, with Ethereum as their flagship. Ethereum has its own programming language, enabling users to write and automate self-executing smart contracts, allowing for the creation of tokens for a specific use. For example, imagine that when Uber was founded, it had created an Uber token, and only people who owned Uber tokens could use the rideshare service. Tokens currently power thousands of decentralized applications that give people more privacy and control in a variety of areas, such as internet browsing, financial services, gaming and data storage, among others.

Some critiques of cryptocurrency remain. One growing concern is that cryptocurrencies require a significant amount of energy to run their networks, leading to higher transaction costs, energy waste and limited scalability. Newer cryptocurrencies are attempting to find ways to verify transactions that require less energy.

Some people also worry about ongoing volatility in cryptocurrency markets. A third generation of cryptocurrencies has emerged to address this concern: so-called “stablecoins,” which are pegged to a government-issued currency, a commodity, assets, or basket of assets. For some, stablecoins are serving as an onramp into the world of crypto from the world of traditional finance.

Before a new technology becomes part of everyday life, we often see a long period of development, improvement and consumer adoption. Cryptocurrency and blockchain markets are still in this early development stage, but they’re also moving quickly into the mainstream. The total market capitalization of cryptocurrencies late last year briefly reached the $3 trillion mark, or roughly 15 percent of the U.S. GDP, and there’s been more than $100 billion locked into decentralized finance applications.

Large companies like IBM, Amazon and Bank of America are leading the way by tapping into blockchain technology in their daily business activities. It won’t be long until this market, previously characterized by speculation and wild volatility, will be transformed into a stable infrastructure framework. But companies need to get up to speed on the industry now. Those that commit to doing so will be the ones that thrive.


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This article originally ran on Rice Business Wisdom and was written by Manolo Sánchez, an adjunct professor of operations management at the Jones Graduate School of Business at Rice University.

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Austin company to bring AI-powered school to The Woodlands

AI education

Austin-based Alpha School, which operates AI-powered private schools, is opening its first Houston-area location in The Woodlands.

The 8,000-square-foot school, scheduled to be ready for the 2026-27 academic year, initially will serve students in kindergarten through eighth grade. Alpha says the school will offer “open workshop spaces and innovative classrooms that support personalized instruction, core academics, leadership development, and real-world life skills.”

Alpha sets aside two hours each school day for the AI-driven, self-paced study of core subjects like math, reading and science. The rest of each school day consists of life-skills workshops focusing on topics such as leadership and financial literacy.

Alpha’s school in The Woodlands has begun accepting applications for the 2026-27 school year. Annual tuition costs $40,000.

“The Woodlands is one of the most dynamic, forward-thinking communities in Texas, and Alpha is proud to bring

an innovative educational model that complements its strong academic foundation,” says Rachel Goodlad, head

of expansion for Alpha.

Founded in 2014, Alpha School combines adaptive technology-driven instruction with immersive life-skills workshops. Its model emphasizes mastery-based learning in core subjects alongside development of communication, critical thinking, financial literacy and leadership skills. It operates more than 15 schools across the country.

Elsewhere in Texas, Alpha operates schools in Austin, Brownsville, Fort Worth and Plano. Alpha also operates 12 Texas Sports Academy campuses in Texas, including locations in Houston, Pearland and Richmond, along with a NextGen Academy esports school in Austin, a school for gifted students in Georgetown, and lower-cost Nova Academy campuses in Austin and Bastrop.

Alpha has fans and critics. While supporters tout students’ high achievement rates, detractors complain about the high tuition and the AI-influenced depersonalization of education.

“Students and our country need to be in relationship with other human beings,” Randi Weingarten, president of the American Federation of Teachers, a teachers union, tells The New York Times. “When you have a school that is strictly AI, it is violating that core precept of the human endeavor and of education.”

Alpha co-founder MacKenzie Price, a podcaster and social media influencer, doesn’t share Weingarten’s views.

“Parents and teachers: We need to embrace this change,” Price wrote after President Trump signed an executive order promoting AI in schools.

The Times notes that Alpha doesn’t employ AI as a tutor or a supplement. Rather, the newspaper says, AI is “the school’s primary educational driver to move students through academic content.”

Houston researcher secures $1.7M to develop drug for aggressive form of breast cancer

cancer research

A University of Houston researcher has joined a $3.2 million effort to develop a new drug designed to attack a cancer-driving protein commonly found in triple-negative breast cancer.

Triple-negative breast cancer (TNBC) is one of the most difficult-to-treat forms of cancer and accounts for 10 percent to 15 percent of all breast cancer cases. The disease gets its name because tumors associated with it test negative for estrogen receptors, progesterone receptors and excess HER2 protein, making it difficult to target. Due to this, TNBC is often treated with general chemotherapy, which can come with negative side effects and drug resistance, according to UH.

UH College of Pharmacy research associate professor Wei Wang is developing a drug that can target the disease more specifically. The drug will target MDM2, a protein often overproduced in TNBC that also contributes to faster tumor growth.

Wang is working on a team led by Wei Li, director of the University of Tennessee Health Science Center College of Pharmacy’s Drug Discovery Center. She has received $1.7 million to support the research.

Wang and UH professor of pharmacology and toxicology Ruiwen Zhang have discovered a compound that can break down MDM2. In early laboratory models, the compound has shown the ability to shrink tumors.

Wang and Zhang will focus on understanding how the treatment works and monitoring its effectiveness in models that closely mirror human disease.

“We will study how the drug targets MDM2 and evaluate the most promising drug candidates to determine effective dosing, understand how the drug behaves in the body, compare it with existing treatments and assess early safety,” Wang said in a news release.

Li’s team at the University of Tennessee will be working on the chemistry and drug design end of the project.

“This work could lead to an entirely new class of therapies for triple-negative breast cancer,” Li added in the release. “We’re hopeful that by directly removing the MDM2 protein from cancer cells, we can help more patients respond to treatment regardless of their tumor type.”