Four Houston entrepreneurs have teamed up to create a program based on each of their expertise that provides a launch pad for aspiring startup founders. Getty Images

For some aspiring startup founders, the biggest thing holding them back is not knowing where to start. A group of former founders and mentors are teaming up to create that first step.

"A few months ago it struck me that maybe there was a gap in the market between the aspiring entrepreneur," says Steve Jennis, "and the accelerator or incubator program."

Jennis, who's a founder, consultant, and mentor in Houston, tapped a few of his fellow founder-mentors to create Founder's Compass, an online masterclass for people who have a business idea but don't know what to do next. Along with Jennis, founder of JCG and PrismTech, the program was created by Brittany Barreto, founder of Pheramor and Femtech Focus; Leela Madan, founder of Madan Law; and Catherine Brown, founder of ExtraBold Sales.

"We thought that the four of us could put together a masterclass comprising of four modules — each module relates to the skill set that we are individually bringing," Jennis tells InnovationMap. "All together, we're representing a framework for new entrepreneurs to get a kickstart to their business and help them with the next step of their journey — whatever that may be."

The four modules will be presented in virtual, interactive classes lasting three hours each and offered in two different ways each month. Students can register for a two-day option — six hours on a Friday followed by another six hours on a Saturday — or a four-week option — three hours on a weeknight once a week for four weeks.

The four modules will cover the following:

  • Validating your business concept and MVP product-market fit (led by Jennis)
  • Customer development, feedback, and target market definition (led Brown)
  • Protecting your intellectual property and managing your business risk (led by Madan)
  • Engaging with the innovation ecosystem and preparing to fundraise (led by Barreto)
Jennis says the program is not intended to be competitive with accelerators, rather Founder's Compass can act as a feeder into these programs. This is why, Jennis says, the masterclass is set up to be relatively cheap at $100 an hour — or $1,200 for the full program.
"We wanted something that was much more convenient, readily available, and easily affordable, so that's why we settled on the two-day or four-evening format to give people something that they didn't have to think about for months," Jennis says. "We saw an opportunity here — not just to be another accelerator — but to be something for people in the game."

Registration for Founder's Compass is open now for September and October, and participants who sign up before August 1 will receive half off — making the course just $600.

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Rice University lands $18M to revolutionize lymphatic disease detection

fresh funding

An arm of the U.S. Department of Health and Human Services has awarded $18 million to scientists at Rice University for research that has the potential to revolutionize how lymphatic diseases are detected and help increase survivability.

The lymphatic system is the network of vessels all over the body that help eliminate waste, absorb fat and maintain fluid balance. Diseases in this system are often difficult to detect early due to the small size of the vessels and the invasiveness of biopsy testing. Though survival rates of lymph disease have skyrocketed in the United States over the last five years, it still claims around 200,000 people in the country annually.

Early detection of complex lymphatic anomalies (CLAs) and lymphedema is essential in increasing successful treatment rates. That’s where Rice University’s SynthX Center, directed by Han Xiao and Lei Li, an assistant professor of electrical and computer engineering, comes in.

Aided by researchers from Texas Children’s Hospital, Baylor College of Medicine, the University of Texas at Dallas and the University of Texas Southwestern Medical Center, the center is pioneering two technologies: the Visual Imaging System for Tracing and Analyzing Lymphatics with Photoacoustics (VISTA-LYMPH) and Digital Plasmonic Nanobubble Detection for Protein (DIAMOND-P).

Simply put, VISTA-LYMPH uses photoacoustic tomography (PAT), a combination of light and sound, to more accurately map the tiny vessels of the lymphatic system. The process is more effective than diagnostic tools that use only light or sound, independent of one another. The research award is through the Advanced Research Projects Agency for Health (ARPA-H) Lymphatic Imaging, Genomics and pHenotyping Technologies (LIGHT) program, part of the U.S. HHS, which saw the potential of VISTA-LYMPH in animal tests that produced finely detailed diagnostic maps.

“Thanks to ARPA-H’s award, we will build the most advanced PAT system to image the body’s lymphatic network with unprecedented resolution and speed, enabling earlier and more accurate diagnosis,” Li said in a news release.

Meanwhile, DIAMOND-P could replace the older, less exact immunoassay. It uses laser-heated vapors of plasmonic nanoparticles to detect viruses without having to separate or amplify, and at room temperature, greatly simplifying the process. This is an important part of greater diagnosis because even with VISTA-LYMPH’s greater imaging accuracy, many lymphatic diseases still do not appear. Detecting biological markers is still necessary.

According to Rice, the efforts will help address lymphatic disorders, including Gorham-Stout disease, kaposiform lymphangiomatosis and generalized lymphatic anomaly. They also could help manage conditions associated with lymphatic dysfunction, including cancer metastasis, cardiovascular disease and neurodegeneration.

“By validating VISTA-LYMPH and DIAMOND-P in both preclinical and clinical settings, the team aims to establish a comprehensive diagnostic pipeline for lymphatic diseases and potentially beyond,” Xiao added in the release.

The ARPA-H award funds the project for up to five years.

Houston doctor wins NIH grant to test virtual reality for ICU delirium

Virtual healing

Think of it like a reverse version of The Matrix. A person wakes up in a hospital bed and gets plugged into a virtual reality game world in order to heal.

While it may sound far-fetched, Dr. Hina Faisal, a Houston Methodist critical care specialist in the Department of Surgery, was recently awarded a $242,000 grant from the National Institute of Health to test the effects of VR games on patients coming out of major surgery in the intensive care unit (ICU).

The five-year study will focus on older patients using mental stimulation techniques to reduce incidences of delirium. The award comes courtesy of the National Institute on Aging K76 Paul B. Beeson Emerging Leaders Career Development Award in Aging.

“As the population of older adults continues to grow, the need for effective, scalable interventions to prevent postoperative complications like delirium is more important than ever,” Faisal said in a news release.

ICU delirium is a serious condition that can lead to major complications and even death. Roughly 87 percent of patients who undergo major surgery involving intubation will experience some form of delirium coming out of anesthesia. Causes can range from infection to drug reactions. While many cases are mild, prolonged ICU delirium may prevent a patient from following medical advice or even cause them to hurt themselves.

Using VR games to treat delirium is a rapidly emerging and exciting branch of medicine. Studies show that VR games can help promote mental activity, memory and cognitive function. However, the full benefits are currently unknown as studies have been hampered by small patient populations.

Faisal believes that half of all ICU delirium cases are preventable through VR treatment. Currently, a general lack of knowledge and resources has been holding back the advancement of the treatment.

Hopefully, the work of Faisal in one of the busiest medical cities in the world can alleviate that problem as she spends the next half-decade plugging patients into games to aid in their healing.