3 Houston innovators to know this week

who's who

This week's roundup of Houston innovators includes Lori-Lee Elliott of Dauntless XR, Sandip Bordoloi of TrueLeap, and Stephanie Nolan of Square Robot. Photos courtesy

Editor's note: Every Monday, I'm introducing you to three Houston innovators to know — three individuals behind recent innovation and startup news stories in Houston as reported by InnovationMap. Learn more about them and their recent news below by clicking on each article.

Lori-Lee Elliott, CEO and co-founder of Dauntless XR

Lori-Lee Elliott of Dauntless XR joins the Houston Innovators Podcast to share about her tech company's evolution. Photo via LinkedIn

As Lori-Lee Elliott was building out her company — an augmented reality software company to enhance industrial workflow — she was approached by a representative in the Air Force interested in her technology. That conversation would end up leading to a major rebrand and pivot, as well as multiple federal contracts and grants for the Houston startup.

Dauntless XR — originally founded as Future Sight AR in 2018 — has two software platforms that bring customers flexible mixed reality solutions. The Air Force uses the Aura platform to create 3D replays of missions, while NASA plans to utilize the technology for analyzing space weather data.

"Something that we realized when we built out this platform is that it doesn't have to be for just one thing," Elliott says on the Houston Innovators Podcast. "We can make it ingest all kind of data sources. It does require us as the developers and the architects to go in and learn about each application. And that's great because I get bored easily and it's an endless source of fascination." Continue reading.

Sandip Bordoloi, CEO and co-founder of TrueLeap

TrueLeap Inc., global digital education startup addressing the digital divide in education, has raised $610,000. Photo via LinkedIn

An edtech startup has just secured funding to further its mission of increasing accessibility to education.

TrueLeap Inc., global digital education startup addressing the digital divide in education, has raised $610,000, which is over its target of $500,000. The round was led by United Kingdom-based Maya Investments Limited.

"This oversubscribed funding round, led by Maya Investments Limited, is a testament to the urgent need for innovative educational technologies in emerging markets. Our commitment to providing affordable and integrated solutions is stronger than ever," says Sandip Bordoloi, CEO and Co-Founder of TrueLeap, in a news release. Continue reading.

Stephanie Nolan, director of sales at Square Robot

It's a different world for startups on the other side of the pandemic — especially for business development. One Houston innovator shares her lessons learned. Photo courtesy of Square Robot

The post-pandemic world of business development has evolved, as Stephanie Nolan, director of sales at Square Robot, has observed. In a guest column for InnovationMap, she shares her experience and lessons learned.

"When I joined the Houston team at Square Robot, a startup that was trying to disrupt an industry, I had to learn how to navigate a post-pandemic sales world — where hybrid work, reliance on emails, and video based web calls are now the norm — coupled with the challenges of working for a relatively new company," she writes.

She shares how she prioritizes in-person meetings and taps into important networking organizations. Continue reading.

Lori-Lee Elliott of Dauntless XR joins the Houston Innovators Podcast to share about her tech company's evolution. Photo via LinkedIn

Houston innovator tackles rebrand, federal grant programs to take XR startup into its new era

HOUSTON INNOVATORS PODCAST EPISODE 221

After entering into these new industries — as well as a 2022 strategic acquisition — Elliott says her team started thinking hard about a rebrand, specifically to set the business up for success as it expands into new fields and opportunities.

"We wanted something that was a name that was a little bit more future proof," Elliott says on the show. "We wanted something that was more representative of this new thing that we had evolved into, and then also something that was going to stand the test of time going forward. We actually really enjoyed the rebrand process."

While Elliott had to learn how to navigate a rebrand, she also juggled the grant and contract process with federal entities — something else that was new to her. Dauntless XR has secured both SBIR and STTR grants and contracts with two different federal agencies, so Elliott has learned a lot.

"The lesson learned I would say is if you're interested in pursuing (grants), go and get all of your government registrations and certifications before you start," Elliott says. "They have fairly quick close deadlines, so when an opportunity opens to when it closes is usually a month. And that is not enough time to register your company at all of the different places it needs to be registered."

She shares more about what she's learned through the past few years or so, as well as what's next for Dauntless XR on the podcast.

A Houston company's technology will help space operators predict coronal mass ejections. Photo via nasa.gov

Houston extended reality company pivots, secures NASA contract

space tech

Following a rebrand, a Houston tech startup has secured a NASA contract for space weather technology.

Dauntless XR received a contract from NASA to advance its spatial computing platform, Aura. The technology uses satellite sensor data and mixed reality to help space operators with weather forecasting, including solar activity.

The company, which was founded by Lori-Lee Elliott as Future Sight AR in 2018 to focus on industrial construction, made a pivot to the space and defense industries and rebranded last year.

"We are in an incredibly interesting stage of space exploration, between record-breaking numbers of satellite launches, missions to the moon and Mars, and even returning asteroid samples to Earth," says Elliott, who serves as CEO, in the release. "With space weather, we are presented with an opportunity to make incredibly complex data easily accessible and provide a platform for innovation — and collaboration — for the space economy and space exploration."

The company is tasked with an extended reality space weather application. Per the release, the app will first be available on the Apple Vision Pro and the Meta Quest devices.

"Our first release will include a special edition of our Aura application with a 3D immersive experience visualizing coronal mass ejections, or CMEs, coming off the sun," the company explains in a blog post. "When a CME hits Earth, it produces auroras, but can also cause power outages, knock out radio signals & GPS, and interfere with rocket launches. As the space economy grows and more people use space data, we hope that our apps make that data easy to access and understand."

The company has also received $1.5 million in United States Air Force contracts. This included two SBIR II contracts that "focused on mixed reality assisted workflows, training and mission planning," according to Dauntless XR. Elliott is based in Houston and the company has offices in Texas, Georgia, Florida, and Hawaii.

Lori-Lee Elliott founded Dauntless XR. Photo via LinkedIn

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Houston researchers develop dissolvable implant for targeted cancer drug delivery

cancer research

Researchers at Houston Methodist have developed a biodegradable implant that can be used to safely and consistently deliver drug treatments to tumors and then dissolve without the need for further surgery.

The implant is only the size of a grain of rice, but its potential is staggering. The biodegradable nanofibrous drug-eluting seed (b-NDES) works as a reservoir parked inside a soft tumor, where it can slowly release immune-stimulating drugs over time. This overcomes a consistent problem with drugs such as immune checkpoint inhibitors. Normal systemic administration sees comparatively little of the drug making its way to the tumor, with most of it circulating throughout the body. The b-NDES is like deploying a small guerrilla fighting force embedded in enemy territory, doing maximum damage to the entrenched tumor.

"To improve cancer treatment, we're trying to start a fire inside the tumor itself," Corrine Chua, associate professor in the Center for BioNanoengineering at Houston Methodist Research Institute, said in a news release. "By activating immune cells directly within the tumor microenvironment, those cells can then travel throughout the body and seek out cancer wherever it exists. The b-NDES platform was developed to help keep therapeutic drugs concentrated inside tumors while minimizing exposure to healthy tissues.”

Chua co-led the study with Alessandro Grattoni, chair and director of the Center for BioNanoengineering at Houston Methodist Research Institute.

The study included support from the Nancy Owens Breast Cancer Foundation and the National Institutes of Health/National Cancer Institute.

Chau and Grattoni used preclinical models of triple-negative breast cancer, an aggressive form of cancer that is estrogen receptor-negative, progesterone receptor-negative and HER2-negative. Because of the receptor negativity, some popular treatments like tamoxifen and trastuzumab are ineffective. Chemotherapy has been shown to be the best course of action.

The b-NDES implant is deployed alongside radiation drugs. It keeps the drugs focused on the tumor, reducing the amount of harmful side effects typically seen when drugs are circulated more widely in the body. In 60 percent of the models, tumors were eliminated and did not cause side effects beyond the tumor site. Once the drugs have been deployed, the implant breaks down naturally.

While promising, more research will have to be done to expand use to other tumor types.

"Although the study focused on triple-negative breast cancer models, the approach could have broader applications for solid tumors," Grattoni added in the release. "It could potentially be used in cancers where there is a tumor lesion accessible for placement, including pancreatic or lung cancers."

New Houston platform Same Day Reels launches for on-demand content creation

In The Moment

If an event doesn't happen on Instagram, did it even really happen? In today's social media-driven age of branding and audience engagement, the answer increasingly is no.

Houston entrepreneur Karen De Amat is looking to fill the online content creation needs of companies with her new venture, Same Day Reels, which launched in early August. It will serve as a platform to connect companies and brands with talent that can help turn an event into a viral moment as it is happening.

"Events move quickly, and social media moves even faster,” said De Amat. “Same Day Reels was built to help brands capture the moment while it still matters. We are creating a more efficient way for businesses and creators to work together. Brands need content faster, and creators need more opportunities to turn their talent into real work. Same Day Reels brings those needs together.”

The company is focused on adding livestreams and concurrent short video content to "activations, launches, fundraisers, grand openings, conferences, hospitality experiences, and private celebrations." Such content can significantly increase the visibility of a product or brand according to digital marketing brands like Wyzowl, whose data found 63 percent of people in 2026 prefer to learn about new products via short video.

Packages offered by Same Day Reels will include filming, editing, and publishing content within hours of the targeted event.

De Amat says that her content creation platform will be a way to preserve the excitement of events and launches by enshrining them with immediate social media-driven memories.

“Event content is no longer just something you post after the fact,” De Amat said. “It is part of how people experience, remember and share the moment.”

Previously, De Amat is also the founder and CEO of Social Behavior, an influencer marketing company she launched from her home in 2014. It quickly garnered an array of clients and thrust De Amat into the spotlight, including numerous appearances on Fox 26's The Isiah Factor. Influencer Marketing Hub named her one of the top CEOs of influencer marketing companies in Houston in 2025.

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This article originally appeared on CultureMap.com.

Bristol Myers Squibb to build $2.3B Houston pharma manufacturing campus

coming soon

New Jersey-based pharmaceutical giant Bristol Myers Squibb Co. has officially named Houston as the home of its new state-of-the-art manufacturing site.

The 60,000-square-foot facility represents a $2.3 billion investment, according to a news release. It is expected to create 500 skilled jobs and will be located in Houston's Generation Park.

BMS first announced that it was considering Houston among 16 other cities for the facility in May. The new hub will manufacture small molecule, biologic and antibody-drug conjugates and is part of a $40 billion commitment to invest in the United States over five years. Construction is slated to begin next year, with the facility coming online in 2030.

"We're building the domestic manufacturing capabilities needed to deliver the next generation of medicines and support future scientific breakthroughs. Houston and the state of Texas offer the talent, infrastructure, and partnership needed to help bring that vision to life," Christopher Boerner, CEO and board chair of BMS, said in the release.

The new facility will feature a modular, multi-modal design, which will allow the company to reconfigure and add to its manufacturing capabilities over time. BMS says it expects the facility to "(grow) in scale and capability well beyond its opening configuration."

"Our decision to build this state-of-the-art manufacturing campus in Houston, Texas, reflects our confidence in the region’s ability to support a world-class, digitally advanced supply operation,” Karin Shanahan, EVP and chief supply chain and operations officer of BMS, added in the release. “This facility is designed to deliver the speed, quality, and reliability that patients depend on, combining flexible, modular manufacturing with advanced digital capabilities to ensure consistent supply across multiple modalities. It strengthens our ability to operate with resilience and positions us to reliably deliver medicines to patients today while adapting future demands.”

Texas Gov. Greg Abbott shared that the state has granted BMS a $4.89 million Texas Enterprise Fund (TEF) grant for the project. TEF grants, administered by the Texas Economic Development & Tourism Office, support business relocation or expansion projects that create "new, good-paying jobs in the community and attract significant new capital investment to the state." The development is also a qualified project under the Texas Jobs, Energy, Technology, and Innovation (JETI) program.

“Texas is a global hub for life sciences, where today’s innovations shape the future of healthcare,” Abbott said in a news release. “This $2.3 billion investment by Bristol Myers Squibb in the dynamic biotech ecosystem in Houston is a testament to the depth of our skilled workforce and the pipeline of talent coming through our nation-leading technical colleges and research universities. With lower operating costs and easy access to markets across the U.S. and the world, Texas drives affordability for consumers.”

"Bristol Myers Squibb’s announcement is a tremendous win for Texas and the Houston region, further reinforcing our position as a premier destination for life sciences and advanced manufacturing,” added Greater Houston Partnership President and CEO Steve Kean.

Last fall, Eli Lilly and Co. selected Generation Park, a 4,300-acre, master-planned commercial district near Lake Houston, for its $6.5 billion manufacturing plant. More than 300 locations in the U.S. competed for the factory. Read more here.

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