Houston named No. 1 most stressful city for workers in U.S. in new report

by the numbers

Work life in H-Town is hard. Photo by Elisa Ventur on Unsplash

Feeling totally stressed about work? Fellow Houstonians feel the pain.

In a new report from LLC.org, Houston was designated the most stressful city to work in. In fact, not one — but five — Texas cities made the top 10 most stressful cities for workers. Ouch.

LLC.org’s analysis looked at eight different categories such as average commute time, average weekly hours worked, income growth rate, and more. Each of the 170-plus cities researched in the report have a population of at least 150,000 people – which adds up to a lot of stressed out folks nationwide.

Houston earned its most stressful city ranking due to its nearly 53-minute average round trip daily commute, not to mention that one in three people in the city are on the road before 7 am every morning. To top it off, Houston’s percentage of workers without health insurance is 30.4 percent, which is significantly higher than the national average of 10.5 percent. (That’s a lot to be stressed about.)

Just after Houston is Arlington (No. 2) and Dallas (No. 3). While Arlington earns its second most stressful city rank for its 39.9 hour average daily work week, Dallas ranked ninth for the longest work week out of all cities in the analysis. The average Dallas laborer works 40.2 hours a week, which is greater than the 38.7 hour national average. At least Dallas’ average commute is a little lower than Houston and Arlington – at 51.4 minutes round trip.

Rounding out the top five are Memphis, Tennessee (No. 4) and Las Vegas, Nevada (No. 5) with Corpus Christi taking the No. 6 spot. Other Texas cities that made the list include Fort Worth (No. 8), San Antonio (No. 12), Garland (No. 13), Brownsville (No. 15), El Paso (No. 22) and Irving (No. 26).

The top 10 most stressful cities for workers are:

  • No. 1: Houston
  • No. 2: Arlington, Texas
  • No. 3: Dallas
  • No 4: Memphis, Tennessee
  • No. 5: Las Vegas
  • No. 6: Corpus Christi, Texas
  • No. 7: Fayetteville, North Carolina
  • No. 8: Fort Worth, Texas
  • No. 9: Moreno Valley, California
  • No. 10: Modesto, California
In an examination of the least stressful cities for workers, not a single Texas city made the top 10. Madison, Wisconsin earned the ranking of least stressful city to work in. It must be nice to have a 36.6-hour average workweek and short average round trip commute of 37.4 minutes. If only.The full report can be found at llc.org.

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This article originally ran on CultureMap.

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Axiom Space-tested cancer drug advances to clinical trials

mission critical

A cancer-fighting drug tested aboard several Axiom Space missions is moving forward to clinical trials.

Rebecsinib, which targets a cancer cloning and immune evasion gene, ADAR1, has received FDA approval to enter clinical trials under active Investigational New Drug (IND) status, according to a news release. The drug was tested aboard Axiom Mission 2 (Ax-2) and Axiom Mission 3 (Ax-3). It was developed by Aspera Biomedicine, led by Dr. Catriona Jamieson, director of the UC San Diego Sanford Stem Cell Institute (SSCI).

The San Diego-based Aspera team and Houston-based Axiom partnered to allow Rebecsinib to be tested in microgravity. Tumors have been shown to grow more rapidly in microgravity and even mimic how aggressive cancers can develop in patients.

“In terms of tumor growth, we see a doubling in growth of these little mini-tumors in just 10 days,” Jamieson explained in the release.

Rebecsinib took part in the patient-derived tumor organoid testing aboard the International Space Station. Similar testing is planned to continue on Axiom Station, the company's commercial space station that's currently under development.

Additionally, the drug will be tested aboard Ax-4 under its active IND status, which was targeted to launch June 25.

“We anticipate that this monumental mission will inform the expanded development of the first ADAR1 inhibitory cancer stem cell targeting drug for a broad array of cancers," Jamieson added.

According to Axiom, the milestone represents the potential for commercial space collaborations.

“We’re proud to work with Aspera Biomedicines and the UC San Diego Sanford Stem Cell Institute, as together we have achieved a historic milestone, and we’re even more excited for what’s to come,” Tejpaul Bhatia, the new CEO of Axiom Space, said in the release. “This is how we crack the code of the space economy – uniting public and private partners to turn microgravity into a launchpad for breakthroughs.”

Houston ranks No. 4 for HQ relocations and more innovation news to know

Trending News

Editor's note: The top recent Houston business and innovation news includes a high ranking for Houston HQs, an innovative exoskeleton designed for children with cerebral palsy, and incoming drones for Walmart delivery. Catch up on the 5 most-read InnovationMap stories from the latter half of June 2025 below:

1. Houston ranks among top 5 cities for corporate HQ relocations in new report

Houston attracted 31 new corporate headquarters from 2018 to 2024, according to a new report from CBRE. Photo via Getty Images

The Houston area already holds the title as the country’s third biggest metro hub for Fortune 500 headquarters, behind the New York City and Chicago areas. Now, Houston can tout another HQ accolade: It’s in a fourth-place tie with the Phoenix area for the most corporate headquarters relocations from 2018 to 2024.

During that period, the Houston and Phoenix areas each attracted 31 corporate headquarters, according to new research from commercial real estate services company CBRE. Continue reading.

2. Texas plugs in among states at highest risk for summer power outages in 2025

A new study puts Texas at No. 2 among the states most at risk for power outages this summer. Photo via Getty Images

Warning: Houston could be in for an especially uncomfortable summer.

A new study from solar energy company Wolf River Electric puts Texas at No. 2 among the states most at risk for power outages this summer. Michigan tops the list. Continue reading.

3. Houston team develops innovative soft skeleton for kids with cerebral palsy

UH BRAIN and TIRR Memorial Hermann have developed the MyoStep soft exoskeleton to address motor impairments caused by cerebral palsy. Photo courtesy UH.

A Houston team has introduced the MyoStep soft exoskeleton for children with cerebral palsy.

The soft skeleton aims to address motor impairments caused by cerebral palsy that impact children’s ability to participate in physical activities, self-care and academics. Continue reading.

4. CPRIT grants $22M to bring top cancer researchers to Houston

CPRIT recently granted $93 million to 61 organizations and scientists, including many in Houston, to advance cancer research. Carter Smith/Courtesy of MD Anderson

Several prominent cancer researchers are coming to the Houston area thanks to $22 million in grants recently awarded by the Cancer Prevention and Research Institute of Texas (CPRIT).

The biggest CPRIT recruitment grant — $6 million — went to genetics researcher Jean Gautier. Gautier, a professor of genetics and development at Columbia University’s Institute for Cancer Genetics, is joining the University of Texas MD Anderson Cancer Center to continue his research. Continue reading.

5. California company to launch Walmart drone delivery in Houston

California company to launch Walmart drone delivery in Houston

Walmart Supercenters in Houston will offer Wing drone delivery services by this time next year. Photo courtesy Wing.

California-based Wing will soon touch down in Houston.

The drone delivery company has partnered with Walmart Supercenters in Houston, Atlanta, Charlotte, Orlando and Tampa. According to a news release, Wing’s drone delivery services will be available at 100 Walmart stores across the selected markets by this time next year. Continue reading.

Chevron enters the lithium market with major Texas land acquisition

to market

Chevron U.S.A., a subsidiary of Houston-based energy company Chevron, has taken its first big step toward establishing a commercial-scale lithium business.

Chevron acquired leaseholds totaling about 125,000 acres in Northeast Texas and southwest Arkansas from TerraVolta Resources and East Texas Natural Resources. The acreage contains a high amount of lithium, which Chevron plans to extract from brines produced from the subsurface.

Lithium-ion batteries are used in an array of technologies, such as smartwatches, e-bikes, pacemakers, and batteries for electric vehicles, according to Chevron. The International Energy Agency estimates lithium demand could grow more than 400 percent by 2040.

“This acquisition represents a strategic investment to support energy manufacturing and expand U.S.-based critical mineral supplies,” Jeff Gustavson, president of Chevron New Energies, said in a news release. “Establishing domestic and resilient lithium supply chains is essential not only to maintaining U.S. energy leadership but also to meeting the growing demand from customers.”

Rania Yacoub, corporate business development manager at Chevron New Energies, said that amid heightening demand, lithium is “one of the world’s most sought-after natural resources.”

“Chevron is looking to help meet that demand and drive U.S. energy competitiveness by sourcing lithium domestically,” Yacoub said.

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This article originally appeared on EnergyCapital.

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