When seven Houston Public Libraries were damaged during Hurricane Harvey, the library system rolled out its resources to the communities that needed it most. Photo courtesy of Houston Public Library Foundation

To those that think the Houston Public Library has a dearth of innovation, think again.

"If people don't think libraries are relevant, they just need to visit one," says Sally Swanson, executive director of the Houston Public Library Foundation. "The 21st century library really is a technology hub.

"The libraries here in Houston have been around over a hundred years, but regardless of what decade it was in, it has always kept up with the needs of the community, therefore it always has to be innovative."

In the aftermath of Hurricane Harvey, seven libraries across Houston were forced to close due to extreme flood damage. To mitigate the loss, the HPL decided to modernize its Mobile Express Unit, a custom-built technology lab and library on wheels designed to bring access to technology and programs to high-need neighborhoods.

"Even though the hurricane was two years ago, the damage in Houston was so extensive, that only one of those seven locations has reopened," says Swanson. "The other ones are still in need, so having the Mobile Express now will bridge that gap until the city is able to reconstruct or reopen those closed locations.

"Thanks to the renovated Mobile Express, we'll be able to go to community centers, to schools and to other events. Basically, we're bringing the library to the people."

With the help of The Brown Foundation Inc., John P. McGovern Foundation, The Powell Foundation, corporate partner Crown Castle and thousands of donations from generous Houstonians, the HPL will use the $325,000 vehicle outfitted with advanced programmatic features to expand services to a growing waiting list of neighborhoods in need.

"We couldn't have done this without the generosity of the Houston community," says Swanson. "The vehicle itself was $325,000 and there was another $30,000 added in for technology. I would really like to thank our significant donors that made this vehicle possible. Thanks to that outpouring of support, this is now our reality."

The Mobile Express Unit, which will begin venturing out and serving the community in early February, has three touchscreen monitors, one desktop tower, 12 student Apple MacBook laptops and 10 iPads in a training room, eight tech lab workstations and a 3D printer.

"Even though we've had the public debut, it hasn't started accepting appointments yet," says Swanson. "The Mobile Express is operated through the Houston Public Library's Community Engagement division. They will have the online schedule and they have a driver and a program team that will go out and bring activities to people. The beauty of this is that it's free to the public."

As a fun way to get the word out, the HPL is sponsoring a contest for kids to name the Mobile Express Unit's robot mascot. Kids that enter the vehicle will be able to use the mascot to learn robotics and whoever wins the naming contest will receive that same robot, with five runners up receiving five slightly smaller versions of the robot.

"The beauty of the Mobile Express is its versatility," says Swanson. "There is a need for getting kids engaged in STEM activities and while some kids are very computer proficient, there are others that don't have access to the equipment. There will be learning at every stage and kids will be able to go on the vehicle, experiment with the different platforms and be part of the technology.

"There will be computer classes, coding classes and 3D printing workshops, so anyone, no matter their level of skills will be able to go on and actually have a real positive hands-on experience."

The Mobile Express, which can serve up to 24 participants or expand its interior walls to accommodate more, has an outdoor flat screen for dance sessions or for showing the instruction that is being held on the inside.

With its improved classroom flow and comfortable and engaging environment, the Mobile Express is able to offer English as a Second Language classes, workforce development classes, sewing workshops and pop-up library activities.

The mobile library and technology lab on wheels has no restrictions on its service area, so it can go into every neighborhood and corner of Houston and serve the public where it is needed the most.

"Every stop the Mobile Express makes is a continued investment into the Houston community," says Swanson. "A lot of people take for granted that everyone has equal access to online resources, but there's a lot of families that are having trouble making ends meet and they don't have internet in their home.

"The Houston Public Library has always been really good about finding creative and innovative ways of bringing services to the community."

For those that can't wait to make an appointment with the Mobile Express, there's always the neighborhood brick-and-mortar library.

"I welcome everyone in Houston to just go visit their local library," says Swanson. "They will be very surprised when they walk in and they see how many people are there reading or on computer terminals. They'll also be surprised by the library's focus on technology."

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Rice Alliance and the Ion leader Brad Burke to retire this summer

lasting legacy

Brad Burke—a Rice University associate vice president who leads the Ion District’s Rice Alliance for Technology and Entrepreneurship and is a prominent figure in Houston’s startup community—is retiring this summer after a 25-year career at the university.

Burke will remain at the Rice Alliance as an adviser until his retirement on June 30.

“Brad’s impact on Rice extends far beyond any single program or initiative. He grew the Rice Alliance from a promising campus initiative into one of the most respected university-based entrepreneurship platforms,” Rice President Reginald DesRoches said in a news release.

During Burke’s tenure, the Rice Business School went from unranked in entrepreneurship to The Princeton Review’s No. 1 graduate entrepreneurship program for the past seven years and a top 20 entrepreneurship program in U.S. News & World Report’s rankings for the past 14 years.

“Brad didn’t just build programs — he built an ecosystem, a culture, and a reputation for Rice that now resonates around the world,” said Peter Rodriguez, dean of the business school. “Through his vision and steady leadership, Rice became a place where founders are taken seriously, ideas are rigorously supported, and entrepreneurship is embedded in the fabric of the university.”

One of Burke’s notable achievements at Rice is the creation of the Rice Business Plan Competition. During his tenure, the competition has grown from nine student teams competing for $10,000 into the world’s largest intercollegiate competition for student-led startups. Today, the annual competition welcomes 42 student-led startups that vie for more than $1 million in prizes.

Away from Rice, Burke has played a key role in cultivating entrepreneurship in the energy sector: He helped establish the Energy Tech Venture Forum along with Houston Energy and Climate Startup Week.

Furthermore, Burke co-founded the Texas University Network for Innovation and Entrepreneurship in 2008 to bolster the entrepreneurship programs at every university in Texas. In 2016, the Rice Alliance assumed leadership of the Global Consortium of Entrepreneurship Centers.

In 2023, Burke received the Trailblazer Award at the 2023 Houston Innovation Awards and was recognized by the Deshpande Foundation for his contributions to innovation and entrepreneurship in higher education.

“Working with an amazing team to build the entrepreneurial ecosystem at Rice, in Houston, and beyond has been the privilege of my career,” Burke said in the release. “It has been extremely gratifying to hear entrepreneurs say our efforts changed their lives, while bringing new innovations to market. The organization is well-positioned to help drive exponential growth across startups, investors, and the entrepreneurial ecosystem.”

Starting April 15, John “JR” Reale Jr. will serve as interim associate vice president at Rice and executive director of the Rice Alliance. He is managing director of the alliance and co-founder of Station Houston, beginning April 15. Reale is co-founder of the Station Houston startup hub and a startup investor and was also recently named director for startups and investor engagement for the Ion.

“The Rice Alliance has always been about helping founders gain advantages to realize their visions,” Reale said. “Under Brad’s leadership, the Rice Alliance has become a globally recognized platform that is grounded in trust and drives transformational founder outcomes. My commitment is to honor what Brad has built and led while continuing to serve our team and community, deepen relationships and deliver impact.”

Burke joined the Houston Innovators Podcast back in 2022. Listen to the full interview here.

Houston team uses CPRIT funding to develop nanodrug for cancer immunotherapy

cancer research

With a relative five-year survival rate of 50 percent, pancreatic cancer is a diagnosis nobody wants. At 60 percent, the prognosis for lung cancer isn’t much rosier. That’s because both cancers contain regulatory B cells (Bregs), which block the body’s natural immunity, making it harder to fight the enemies within.

Newly popular immunotherapies in a category known as STING agonists may stimulate natural cancer defenses. However, they can also increase Bregs while simultaneously causing significant side effects. But Wei Gao, assistant professor of pharmacology at the University of Houston College of Pharmacy, may have a solution to that conundrum.

Gao and her team have developed Nano-273, a dual-function drug, packaged in an albumin-based particle, that boosts the immune system to help it better fight pancreatic and lung cancers. Gao’s lab recently received a $900,000 grant from the Cancer Prevention and Research Institute of Texas (CPRIT) to aid in fueling her research into the nanodrug.

“Nano-273 both activates STING and blocks PI3Kγ—a pathway that drives Breg expansion, while albumin nanoparticles help deliver the drug directly to immune cells, reducing unwanted side effects,” Gao said in a press release. “This approach reduces harmful Bregs while boosting immune cells that attack cancer, leading to stronger and more targeted anti-tumor responses.”

In studies using models of both pancreatic and lung cancers, Nano-273 has shown great promise with low toxicity. Its best results thus far have involved using the drug in combination with immunotherapy or chemotherapy.

With the CPRIT funds, Gao and her team will be able to charge closer to clinical use with a series of important steps. Those include continuing to test Nano-273 alongside other drugs, including immune checkpoint inhibitors. Safety studies will follow, but with future patients in mind, Gao will also work toward improving her drug’s production, making sure that it’s safe and high-quality every time, so that it is eventually ready for trials.

Gao added: “If successful, this project could lead to a new type of immunotherapy that offers lasting tumor control and improved survival for patients with pancreatic and lung cancers, two diseases that urgently need better treatments."

Houston booms as No. 2 U.S. metro for new home construction

Construction Boom

Driven by population growth, more residential rooftops are popping up across Houston and the rest of Texas than anywhere else in America.

Using data from the U.S. Census Bureau and Zillow, Construction Coverage found 65,747 new residential units were authorized in greater Houston in 2024. That figure landed Houston in second place among major metro areas for the total number of housing permits, including those for single-family homes, apartments, and condos.

Just ahead of Houston was the Dallas-Fort Worth Metroplex, which took first place with 71,788 residential permits approved in 2024. In third place was the country’s largest metro, New York City (57,929 permits).Elsewhere in Texas, the Austin metro ranked sixth (32,294 permits), and the San Antonio metro ranked 20th (14,857 permits).

Construction Coverage also sorted major metro areas based on the number of new housing units authorized per 1,000 existing homes in 2024. Raleigh, North Carolina, held the No. 1 spot (28.8 permits per 1,000 existing homes), followed by Austin at No. 2 (28.6), DFW at No. 3 (22.2), Houston at No. 4 (21.6), and San Antonio at No. 13 (13.6).

A Newsweek analysis of Census Bureau data shows building permits for 225,756 new residential units were approved in 2024 in Texas — a trend fueled largely by activity in DFW, Houston, Austin, and San Antonio. That put Texas atop the list of states building the most residential units for the year.

Through the first eight months of last year, 145,901 permits for new residential units were approved in Texas, according to Census Bureau data. That’s nearly 80,000 permits shy of the 2024 total.

Among the states, Construction Coverage ranks Texas sixth for the number of residential building permits approved in 2024 per 1,000 existing homes (17.9).

Extra housing is being built in Texas to meet demand spurred by population growth. From April 2020 to July 2024, the state’s population increased 7.3 percent, the Census Bureau says.

While builders are busy constructing new housing in Texas, they’re not necessarily profiting a lot from homebuilding activity.

“Market conditions remain challenging, with two-thirds of builders reporting they are offering incentives to move buyers off the fence,” North Carolina homebuilder Buddy Hughes, chairman of the National Association of Home Builders, said in a December news release. “Meanwhile, builders are contending with rising material and labor prices, as tariffs are having serious repercussions on construction costs.”