Watch elite gamers face off in League of Legends. Photo by Jamie McInall/Pexels

Heads up, gamers. The most popular esport is coming to the Bayou City. The League Championship Series (LCS), will host its marquee championship event at NRG Stadium (8825 Kirby Dr.) on April 23 and 24, the organization announced.

Not only is this the first time the tournament will be held in Texas, it’s also the first time the prestigious League of Legends competition — the LCS Spring Finals — will be hosted in an NFL stadium. For the uninitiated, League of Legends is a wildly popular, team-based multiplayer strategy game.

Houston fans are invited to attend both the pregame Fan Fest celebration and the LCS Finals, a first since the pandemic. The Fan Fest starts at 10 am Saturday, April 23, and the first match starts at 2:30 pm.

As the league’s first seasonal championship event of the year, the competition will see North America’s top three teams vie for an LCS trophy, a banner in the LCS Studio rafters, and an invite to the international Mid-Season Invitational in Busan, South Korea next month, per a release.

Developed and run by influential and prolific developer and publisher Riot Games, this championship will be held in North America across four cities — Mexico City, New York City, Toronto and San Francisco, a first since 2016, a release notes.

As the most-watched esport in the world with 12 international leagues, the 10-year-old LCS is actually the third-most popular major professional sports league among 18- to 34-year-olds in the U.S., per industry insiders.

For some perspective, more than 465 million people watched esports in 2021. Esports generated more than $1 billion in revenue, according to a Newzoo report.

For more information on the Fan Fest and tournament, visit the official site.

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This article originally ran on CultureMap.

Houston-based Mainline has announced new partnerships with a few universities. Jamie McInall/Pexels

Houston esports company taps nearby universities for partnerships

Game on

A Houston esports platform has announced that four universities — including one in town — have made moves to optimize the company's technology.

Texas A&M University, the University of Texas - Austin, Louisiana State University, and Houston's own University of St. Thomas have made a deal with Mainline. The company, which just closed a $9.8 million series A round, is a software and management platform for esports tournaments.

The four schools will use the software to host and grow their on-campus esports communities, according to a news release.

"These are top universities seeing the value of esports on-campus and making a choice to support their students' desires to play and compete — much like in traditional sports," says Chris Buckner, CEO at Mainline, in the release. "Adoption of Mainline is validation of the opportunity to engage students and the broader community with a compelling esports platform, as well as strengthen a school's brand, provide additional partnership opportunities and market their initiatives"

While UST has is still in the process of utilizing Mainline for its esports platform to grow its program and will use the software for its first tournament in 2020, A&M first used Mainline's software this past spring, but has doubled down on its commitment to esports.

"Texas A&M recognizes the significant esports presence on campus and the importance of supporting this thriving student community. Mainline allows us to maintain the brand continuity of the university, and to drive incremental inventory and value for sponsors," says Mike Wright, director of public relations and strategic communications at Texas A&M Athletics, in the release.

The platform provides its clients with an easy way to manage, monetize, and market their tournaments.

At UT, the school's administration, along with its Longhorn Gaming Club, is currently running two tournaments on Mainline: Rocket League and League of Legends.

"Texas has had a long established esports community on campus, and our partnership with Mainline will enable us to more closely work with Longhorn Gaming to better support this audience to benefit our students and partners," says Mike Buttersworth, director of the Center for Sports Communication and Media at UT, in the release.

Meanwhile at LSU, the university is running an esports Rocket League qualifying tournament on the Houston company's platform to select a three-student team to represent the school at the inaugural "Power Five Esports Invitational" in New York in January, according to the release.

"This kind of tournament is a first for our campus, and Mainline is making it easy for us to be able to host this qualifying tournament for our students to ultimately represent our university at the Power Five Esports invitational," says Robert Munson, senior associate athletics director at LSU.

As for Mainline, these four schools are just the beginning for universities using the platform.

"Mainline is continuing this collegiate momentum with another 10 powerhouse universities expected to come aboard our platform by the end of 2019, and 50 more by the spring 2020," says Buckner.

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UH lands $4M NIH grant to study early signs of autoimmune disease

NIH funding

The University of Houston recently received a $4 million National Institutes of Health grant to support a 10-year longitudinal study to identify the earliest biological markers of autoimmune disease.

Led by Chandra Mohan, the Hugh Roy and Lillie Cranz Cullen Endowed Professor of Biomedical Engineering, the study aims to examine what causes Systemic Autoimmune Rheumatic Diseases (SARDs) and to identify targets for future treatments. The study will be carried out in collaboration with Dr. Karen Costenbader at Harvard Medical School, Boston.

SARDs include conditions like rheumatoid arthritis, systemic lupus erythematosus, Sjögren’s syndrome and systemic sclerosis—all are considered chronic diseases currently without a cure. Autoimmune diseases affect over 30 million people globally, according to UH.

SARDs occur when the body’s immune system attacks healthy, non-threatening tissues and organs. According to UH, in these diseases, the body often attacks nuclear antigens, creating anti-nuclear autoantibodies, which can be early detection signs for SARDs in more than 50 percent of patients, Mohan says.

Researchers will study blood samples and environmental exposure over the 10 years to better understand anti-nuclear autoantibodies.

“Collectively, these studies will help identify the genetic, environmental and cellular factors that are operative at the two steps of SARD development, namely the emergence of anti-nuclear autoantibodies and disease onset,” Mohan said in a news release. “ More importantly, these studies will highlight functional molecular pathways and mechanisms that may be operative at each step."

Mohan predicts that looking at SARDs’ shared characteristics, rather than each disease individually, could help identify more treatment methods.

“Individual SARDs have been examined in silos without an attempt to discern shared underlying features at the molecular level,” he added in the release. “Current understanding of the initial (and likely shared) origins of SARDs is only rudimentary but urgently needed to develop means for prevention and treatment.”

Earlier this year, UH also received an $11 million NIH grant to conduct a first-of-its-kind study of early language development in children ages 18 to 24 months. Read more here.

New Texas Stock Exchange officially begins trading in Dallas

Welcome to Y'all Street

Two-step aside, New York Stock Exchange and Nasdaq. The Dallas-based Texas Stock Exchange, nicknamed Y’all Street, just kicked off live trading with five stocks — and lots of Lone Star ambition.

“The Texas Stock Exchange aims to revitalize competition for [stock] issuers, establish the premier venue for listings, and create a world-class trading platform for all market participants,” the exchange says in a fact sheet.

The exchange — whose Texas-influenced nickname is a nod to New York City’s Wall Street — has collected at least $275 million in investments. The roughly 90 financial backers of TXSE include Bank of America, BlackRock, Charles Schwab, Citadel Securities, Dell Family Office, Fortress, Goldman Sachs, and JPMorgan Chase.

Representatives of TXSE couldn’t be reached for comment. On its website, the exchange calls itself “the most well-capitalized equities exchange to ever be approved” by the U.S. Securities and Exchange Commission (SEC).

Not to be outdone, NYSE has launched Dallas-based NYSE Texas and Nasdaq has expanded its presence in Dallas.

Y’all Street adds to Dallas-Fort Worth’s rising status as a major hub for financial services, with The Wall Street Journal naming North Texas the country’s second biggest financial hub after New York City.

“A homegrown national exchange means more jobs, more investment, and more growth opportunities for businesses and communities across the Lone Star State,” Gabriela von zur Muehlen, senior vice president and chief policy officer at the Texas Association of Business, told The Texas Tribune.

Bulent Temel, an associate professor of practice in economics at the University of Texas at San Antonio, told Texas Standard that TXSE “is going to boost the credibility of the Texas economy.”

Texas’ estimated gross domestic product (GDP), a yardstick for the size of an economy, climbed to a record-setting $2.9 trillion in 2025, making it the state with the second highest GDP after California. DFW’s estimated GDP in 2023 stood at $744.6 billion, eclipsing the GDP of many countries.

“The center of gravity for American capitalism is now headquartered in the Boom Belt,” Abbott proclaimed in April, referring to an 11-state region (including Texas) in the South and Southeast that’s seeing tremendous economic and population growth. “The Texas Stock Exchange is the natural extension of that capitalism. It ensures that capital markets will reflect the quadrant that is driving American growth.”

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This article originally appeared on CultureMap.com.

Orion vehicle manager reflects on Artemis II, looks to 2028 moon mission

Q&A

Humanity is finally headed back to the moon after more than half a century. This year's launch of the Artemis II mission in the Orion spacecraft put four crew members in lunar orbit and tested the new ship developed by Lockheed Martin.

Everything went smoothly, safely returning astronauts home, but there is always room to improve. InnovationMap chatted via email with Orion vehicle manager Branelle Rodriguez, shortly after a talk at The Ion, for insight on how Orion might perform in the future as the next lunar landing approaches in early 2028.

InnovationMap: How satisfied are you with the way Orion operated on this past mission?

Branelle Rodriguez: Orion performed exceptionally well during Artemis II, successfully demonstrating critical spacecraft capabilities, including life support systems, displays and controls, and executing manual piloting operations. Artemis II brought humans back to the moon, achieving key exploration and scientific imagery, while validating systems essential for future Artemis missions.

IM: What is the most important thing you learned about improving Orion for the next mission?

BR: The Artemis II mission provided invaluable insights into crew operations and spacecraft performance in a deep-space environment. With every mission, NASA applies lessons learned to continuously improve Orion’s operations, validate design and ensure mission readiness. Artemis II offered our first opportunity to evaluate several new systems and gain a deeper understanding of what it is like for astronauts to live and work inside the spacecraft. The operational, technical and human factors data collected are being integrated across the program to refine future missions, reduce risk and enhance overall mission success.

IM: How has Orion helped the mission to explore space?

BR: Orion is one of NASA’s foundational elements for human deep space exploration—not only supporting the mission but serving as a core component of it. It is currently the only spacecraft capable of carrying crew on deep space missions and returning them safely to Earth from the high speeds required from the vicinity of the moon. No other spacecraft has the technology to endure the extremes that come with human deep-space travel, such as advanced environmental and life support, navigation, communications, radiation shielding, and the world’s largest ablative heat shield to protect the astronauts during reentry into Earth’s atmosphere. Orion has already taken astronauts to explore space farther than ever before—252,756 miles from Earth— and will carry crews to the moon on future missions to explore the lunar South Pole region. The astronauts’ observations, samples, and data collected on these future missions will expand our understanding of our solar system and home planet.

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This conversation has been edited for brevity and clarity.