This week's roundup of Houston innovators includes Melanie Johnson of Collaborative for Children, Aditya Mohite of Rice University, Lani Doyle of Cart.com. Photos courtesy

Editor's note: Every week, I introduce you to a handful of Houston innovators to know recently making headlines with news of innovative technology, investment activity, and more. This week's batch includes a nonprofit leader introducing new technologies, a solar tech-focused Rice University professor, and a new hire for a Houston fast-growing startup.

Melanie Johnson, president and CEO of Collaborative for Children

Collaborative for Children is focused on utilizing social-emotional learning robots and coding tech toys. Photo courtesy

Generally, when children are under the age of five, educators believe that they are best suited for and interested in learning, because those are the years in which there is the strongest opportunity to build a broad and solid foundation for lifelong literacy and well-being.

That sentiment is deeply held by Collaborative for Children, the Houston-based nonprofit organization with the mission to meaningfully improve the quality of early childhood education and provide access to cutting-edge technology through its Centers of Excellence to all children, especially those in low-income and marginalized communities.

“The reason the organization was started about 40 years ago is that a group of philanthropists in the greater Houston area suggested that this was so important because 90 percent of the brain develops or grows in the time frame between ages zero to five years of age,” Melanie Johnson, president and CEO of Collaborative for Children, tells InnovationMap. Read more.

Aditya Mohite, director of Rice Engineering Initiative for Energy Transition and Sustainability

The new process developed by Rice University researchers makes solar cells that are about 10 times more durable than traditional methods. Photo courtesy

Presented on the cover of a June issue of Science, a study from Rice University engineer Aditya Mohite's lab uncovered a method to synthesize a high-efficiency perovskite solar cell, known as formamidinium lead iodide (FAPbI3), converting them into ultrastable high-quality photovoltaic films, according to a statement from Rice. Photovoltaic films convert sunlight into electricity.

The new process makes solar cells that are about 10 times more durable than traditional methods.

“Right now, we think that this is state of the art in terms of stability,” Mohite said in a statement. “Perovskite solar cells have the potential to revolutionize energy production, but achieving long-duration stability has been a significant challenge.” Read more.

Lani Doyle, chief people officer at Cart.com

Fast-growing Cart.com has named its new chief people officer. Photo courtesy of Cart.com

Houston-based e-commerce software and services company Cart.com has hired a former Shopify executive as its chief people officer.

Before joining Cart.com, Lani Doyle was chief HR officer at Strategic Solutions Group, a provider of health care software. Previously, she was vice president of HR and people operations at 6 River Systems, a provider of software and robotics for warehouses. Prior to that, Doyle was head of talent development and operations at Shopify, an e-commerce platform for businesses that posted revenue of $7.1 billion in 2023.

“Cart.com is one of the fastest-growing companies in commerce today, and I’m excited to partner with our teams to help drive growth and scalability,” Doyle says in a news release. “I am eager to contribute to shaping our culture and developing programming that supports and elevates high-performing teams, ensuring we achieve our ambitious goals.” Read more.

Fast-growing Cart.com has named its new chief people officer. Photo courtesy of Cart.com

Former Shopify exec joins Houston scale-up e-commerce software company

joining the team

Houston-based e-commerce software and services company Cart.com has hired a former Shopify executive as its chief people officer.

Before joining Cart.com, Lani Doyle was chief HR officer at Strategic Solutions Group, a provider of health care software. Previously, she was vice president of HR and people operations at 6 River Systems, a provider of software and robotics for warehouses. Prior to that, Doyle was head of talent development and operations at Shopify, an e-commerce platform for businesses that posted revenue of $7.1 billion in 2023.

Cart.com is one of the fastest-growing companies in commerce today, and I’m excited to partner with our teams to help drive growth and scalability,” Doyle says in a news release. “I am eager to contribute to shaping our culture and developing programming that supports and elevates high-performing teams, ensuring we achieve our ambitious goals.”

Omair Tariq, founder and CEO of Cart.com, describes Doyle as a “strategic leader” who will help develop the startup’s continually growing team. The company, founded in 2020 in Houston, employs more than 1,600 people.

“Her deep expertise in HR strategy and talent development will be instrumental as we accelerate our growth trajectory and foster a dynamic workplace culture,” says Frank Parker, chief operating officer of Cart.com.

In February, Cart.com made another high-level executive move by promoting Joe Barth from senior vice president of fulfillment to chief logistics officer.

Cart.com has more than 6,000 customers. The company handles more than 75 million orders per year from 14 fulfillment centers in the U.S.

Earlier this year, Tariq joined the Houston Innovators Podcast to share a bit about his company's growth and its relocation from Austin back to Houston.

"I think Austin served its purpose. It certainly allowed us to be in the limelight in all the right ways, and I'm grateful for it," Tariq says on the show. "But once we got to a point, once we closed our series C round and became a unicorn ... I think we're now at a scale where the infrastructure that Houston provides is probably something that will be more attractive and useful for us in the long term."

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Austin company to bring AI-powered school to The Woodlands

AI education

Austin-based Alpha School, which operates AI-powered private schools, is opening its first Houston-area location in The Woodlands.

The 8,000-square-foot school, scheduled to be ready for the 2026-27 academic year, initially will serve students in kindergarten through eighth grade. Alpha says the school will offer “open workshop spaces and innovative classrooms that support personalized instruction, core academics, leadership development, and real-world life skills.”

Alpha sets aside two hours each school day for the AI-driven, self-paced study of core subjects like math, reading and science. The rest of each school day consists of life-skills workshops focusing on topics such as leadership and financial literacy.

Alpha’s school in The Woodlands has begun accepting applications for the 2026-27 school year. Annual tuition costs $40,000.

“The Woodlands is one of the most dynamic, forward-thinking communities in Texas, and Alpha is proud to bring

an innovative educational model that complements its strong academic foundation,” says Rachel Goodlad, head

of expansion for Alpha.

Founded in 2014, Alpha School combines adaptive technology-driven instruction with immersive life-skills workshops. Its model emphasizes mastery-based learning in core subjects alongside development of communication, critical thinking, financial literacy and leadership skills. It operates more than 15 schools across the country.

Elsewhere in Texas, Alpha operates schools in Austin, Brownsville, Fort Worth and Plano. Alpha also operates 12 Texas Sports Academy campuses in Texas, including locations in Houston, Pearland and Richmond, along with a NextGen Academy esports school in Austin, a school for gifted students in Georgetown, and lower-cost Nova Academy campuses in Austin and Bastrop.

Alpha has fans and critics. While supporters tout students’ high achievement rates, detractors complain about the high tuition and the AI-influenced depersonalization of education.

“Students and our country need to be in relationship with other human beings,” Randi Weingarten, president of the American Federation of Teachers, a teachers union, tells The New York Times. “When you have a school that is strictly AI, it is violating that core precept of the human endeavor and of education.”

Alpha co-founder MacKenzie Price, a podcaster and social media influencer, doesn’t share Weingarten’s views.

“Parents and teachers: We need to embrace this change,” Price wrote after President Trump signed an executive order promoting AI in schools.

The Times notes that Alpha doesn’t employ AI as a tutor or a supplement. Rather, the newspaper says, AI is “the school’s primary educational driver to move students through academic content.”

Houston researcher secures $1.7M to develop drug for aggressive form of breast cancer

cancer research

A University of Houston researcher has joined a $3.2 million effort to develop a new drug designed to attack a cancer-driving protein commonly found in triple-negative breast cancer.

Triple-negative breast cancer (TNBC) is one of the most difficult-to-treat forms of cancer and accounts for 10 percent to 15 percent of all breast cancer cases. The disease gets its name because tumors associated with it test negative for estrogen receptors, progesterone receptors and excess HER2 protein, making it difficult to target. Due to this, TNBC is often treated with general chemotherapy, which can come with negative side effects and drug resistance, according to UH.

UH College of Pharmacy research associate professor Wei Wang is developing a drug that can target the disease more specifically. The drug will target MDM2, a protein often overproduced in TNBC that also contributes to faster tumor growth.

Wang is working on a team led by Wei Li, director of the University of Tennessee Health Science Center College of Pharmacy’s Drug Discovery Center. She has received $1.7 million to support the research.

Wang and UH professor of pharmacology and toxicology Ruiwen Zhang have discovered a compound that can break down MDM2. In early laboratory models, the compound has shown the ability to shrink tumors.

Wang and Zhang will focus on understanding how the treatment works and monitoring its effectiveness in models that closely mirror human disease.

“We will study how the drug targets MDM2 and evaluate the most promising drug candidates to determine effective dosing, understand how the drug behaves in the body, compare it with existing treatments and assess early safety,” Wang said in a news release.

Li’s team at the University of Tennessee will be working on the chemistry and drug design end of the project.

“This work could lead to an entirely new class of therapies for triple-negative breast cancer,” Li added in the release. “We’re hopeful that by directly removing the MDM2 protein from cancer cells, we can help more patients respond to treatment regardless of their tumor type.”