From opening Nap Bar and consulting corporations on diversity and inclusion to serving the city as an LGBT adviser, Khaliah Guillory is focused on productivity. Courtesy of Khaliah Guillory

Khaliah Guillory is an avid napper — and she's had to be. A multiple hat wearer and big proponent of side hustles, she's always piled responsibilities high on her plate.

Earlier this year left a corporate leadership position to open Nap Bar in Rice Village, but for years before that, she had her diversity and inclusion side hustle, KOG & Company. She works with companies — big and small — to integrate the best diversity and inclusion initiatives into the workplace.

"The intersection between KOG and Nap Bar and the common denominator is productivity and performance," Guillory says. "From a corporate standpoint — even when you think about diversity and inclusion — it all boils down to we want people who don't look like us or don't come from where we come from to be productive and perform well."

Guillory, who is this week's Pride Month Featured Innovator on InnovationMap, also serves on Mayor Sylvester Turner's LGBT Advisory Board.

InnovationMap: When did you know you wanted to be an entrepreneur?

Khaliah Guillory: I was 8 or 9 years old, and my family drank a lot of soda. Where I grew up in Port Arthur, Texas, you could go and trade in cans for change. I would go outside, line up all the cans, and step on them to crush them. I saw an infomercial about a can crusher. It made my business more efficient. That's when my entrepreneurial journey started.

IM: How did The Nap Bar come about? 

KG: I have always been an avid napper. When I was in Kindergarten, and the teacher would say go grab your red or blue mat, I did it and I was out. I enjoyed naptime. In high school, I played basketball and I napped at the end of school. When I got into college, I played basketball at the University of Central Florida. My days would start at 5 am and wouldn't end until midnight. The only way I was able to graduate on time and maintain my grades for my scholarships was napping. It just continued throughout my professional career, and I started napping in my car.

One day, my wife and I commuted into the city — we live in the Sugar Land/Richmond area. We had about an hour and a half to spare. It was nap time, but it would be awkward with her in the car. She suggested Googling naps in Houston. She says, "We live in Houston, there's got to be a place where you could take a quick nap." There was no such place. She told me I should create it. That was April of last year.

IM: Then what did you do to get the ball rolling?

KG: The next day I surveyed all my friends and asked them if I was the only one out here napping. I quickly realized that I wasn't. Specifically, 52 percent of Americans, according to Amerisleep, admitted to napping at work. I committed to doing more research. I've committed 10,000 plus hours to researching the benefits to napping and the indicators of sleep exhaustion. Fast forward to November of last year, I transitioned away from my C-level position at a Fortune 500 company to really pursue Nap Bar.

IM: How’s business been?

KG: We just celebrated our 30th day of business a couple of weeks ago. We are already generating revenue. We are excited for what's to come. June is shaping up to be a real opportunity for us to be in the black, and July is shaping up to have a lot of events. We found that our biggest challenge is educating the masses on the benefits of taking a chill session in the middle of the day, and also educating on the indicators of what it's like to be sleep deprived.

IM: With KOG & Company, your other company, you’ve worked for years with large companies to help incorporate diversity and inclusion. How does that tie into your nap research?

KG: The intersection between KOG and Nap Bar and the common denominator is productivity and performance. From a corporate standpoint — even when you think about diversity and inclusion — it all boils down to we want people who don't look like us or don't come from where we come from to be productive and perform well. The best place for any corporation that has a philosophy or a vision of values and embraces corporate social responsibility is to acknowledge that people are going to be the heartbeat of their company.

IM: What do organizations — from startups to Fortune 500 companies — need to know about diversity and inclusion?

KG: The biggest thing is that from a culture standpoint, just simply hiring people to check a box isn't going to provide the desired ROI. It really, truly has to be embraced by the culture. If I am a business owner or corporation, and my goal is to have a diversity of talent, then I need to go where those people are. If I create and curate an environment with diversity and inclusivity, then going to recruit and then ask them what type of organization they want to work for and what it would look like — then go out and build that. And if they don't know where to start, they can hire me and I can hold their hand and give some real life experience. I've lived it as a banker, as a supervisor, and as a C-level executive.

IM: What’s surprised you about being on Mayor Sylvester Turner’s LGBT Advisory Board?

KG: I think what surprised me most about is that the city of Houston is really progressing and striving. It just makes sense. We're the most diverse city in the country, and I applaud Mayor Sylvester Turner for assembling the LGBT Advisory Board and for appointing me.

The city of Houston — and all the entities that fall under it from a government landscape — is desiring a journey to get more training and education. How do we educate on how to report a hate crime. How do we make sure that city employees are showing up to work and are 100 percent comfortable in their own skin. The biggest surprise I'd have to say is that the city has done an incredible job with the training. I walked away from the meeting learning things that I didn't even know about the LGBTQ community.

IM: What does Pride Month mean to you?

KG: Pride means to me being comfortable in my skin as I am, who I am. The month is a pleasant reminder to be "me" every day, all day. Pride month means my uniqueness is celebrated, not tolerated which should be the norm everyday; not just a month. Pride means being secure in the community — workplace, networking event, the gym, basically everywhere — and confidently say "my wife."

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Portions of this interview have been edited.

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Houston scientists develop breakthrough AI-driven process to design, decode genetic circuits

biotech breakthrough

Researchers at Rice University have developed an innovative process that uses artificial intelligence to better understand complex genetic circuits.

A study, published in the journal Nature, shows how the new technique, known as “Combining Long- and Short-range Sequencing to Investigate Genetic Complexity,” or CLASSIC, can generate and test millions of DNA designs at the same time, which, according to Rice.

The work was led by Rice’s Caleb Bashor, deputy director for the Rice Synthetic Biology Institute and member of the Ken Kennedy Institute. Bashor has been working with Kshitij Rai and Ronan O’Connell, co-first authors on the study, on the CLASSIC for over four years, according to a news release.

“Our work is the first demonstration that you can use AI for designing these circuits,” Bashor said in the release.

Genetic circuits program cells to perform specific functions. Finding the circuit that matches a desired function or performance "can be like looking for a needle in a haystack," Bashor explained. This work looked to find a solution to this long-standing challenge in synthetic biology.

First, the team developed a library of proof-of-concept genetic circuits. It then pooled the circuits and inserted them into human cells. Next, they used long-read and short-read DNA sequencing to create "a master map" that linked each circuit to how it performed.

The data was then used to train AI and machine learning models to analyze circuits and make accurate predictions for how untested circuits might perform.

“We end up with measurements for a lot of the possible designs but not all of them, and that is where building the (machine learning) model comes in,” O’Connell explained in the release. “We use the data to train a model that can understand this landscape and predict things we were not able to generate data on.”

Ultimately, the researchers believe the circuit characterization and AI-driven understanding can speed up synthetic biology, lead to faster development of biotechnology and potentially support more cell-based therapy breakthroughs by shedding new light on how gene circuits behave, according to Rice.

“We think AI/ML-driven design is the future of synthetic biology,” Bashor added in the release. “As we collect more data using CLASSIC, we can train more complex models to make predictions for how to design even more sophisticated and useful cellular biotechnology.”

The team at Rice also worked with Pankaj Mehta’s group in the department of physics at Boston University and Todd Treangen’s group in Rice’s computer science department. Research was supported by the National Institutes of Health, Office of Naval Research, the Robert J. Kleberg Jr. and Helen C. Kleberg Foundation, the American Heart Association, National Library of Medicine, the National Science Foundation, Rice’s Ken Kennedy Institute and the Rice Institute of Synthetic Biology.

James Collins, a biomedical engineer at MIT who helped establish synthetic biology as a field, added that CLASSIC is a new, defining milestone.

“Twenty-five years ago, those early circuits showed that we could program living cells, but they were built one at a time, each requiring months of tuning,” said Collins, who was one of the inventors of the toggle switch. “Bashor and colleagues have now delivered a transformative leap: CLASSIC brings high-throughput engineering to gene circuit design, allowing exploration of combinatorial spaces that were previously out of reach. Their platform doesn’t just accelerate the design-build-test-learn cycle; it redefines its scale, marking a new era of data-driven synthetic biology.”

Axiom Space wins NASA contract for fifth private mission, lands $350M in financing

ready for takeoff

Editor's note: This story has been updated to include information about Axiom's recent funding.

Axiom Space, a Houston-based space infrastructure company that’s developing the first commercial space station, has forged a deal with NASA to carry out the fifth civilian-staffed mission to the International Space Station.

Axiom Mission 5 is scheduled to launch in January 2027, at the earliest, from NASA’s Kennedy Space Center in Florida. The crew of non-government astronauts is expected to spend up to 14 days docked at the International Space Station (ISS). Various science and research activities will take place during the mission.

The crew for the upcoming mission hasn’t been announced. Previous Axiom missions were commanded by retired NASA astronauts Michael López-Alegría, the company’s chief astronaut, and Peggy Whitson, the company’s vice president of human spaceflight.

“All four previous [Axiom] missions have expanded the global community of space explorers, diversifying scientific investigations in microgravity, and providing significant insight that is benefiting the development of our next-generation space station, Axiom Station,” Jonathan Cirtain, president and CEO of Axiom, said in a news release.

As part of Axiom’s new contract with NASA, Voyager Technologies will provide payload services for Axiom’s fifth mission. Voyager, a defense, national security, and space technology company, recently announced a four-year, $24.5 million contract with NASA’s Johnson Space Center in Houston to provide mission management services for the ISS.

Axiom also announced today, Feb. 12, that it has secured $350 million in a financing round led by Type One Ventures and Qatar Investment Authority.

The company shared in a news release that the funding will support the continued development of its commercial space station, known as Axiom Station, and the production of its Axiom Extravehicular Mobility Unit (AxEMU) under its NASA spacesuit contract.

NASA awarded Axiom a contract in January 2020 to create Axiom Station. The project is currently underway.

"Axiom Space isn’t just building hardware, it’s building the backbone of humanity’s next era in orbit," Tarek Waked, Founding General Partner at Type One Ventures, said in a news release. "Their rare combination of execution, government trust, and global partnerships positions them as the clear successor-architect for life after the ISS. This is how the United States continues to lead in space.”

Houston edtech company closes oversubscribed $3M seed round

fresh funding

Houston-based edtech company TrueLeap Inc. closed an oversubscribed seed round last month.

The $3.3 million round was led by Joe Swinbank Family Limited Partnership, a venture capital firm based in Houston. Gamper Ventures, another Houston firm, also participated with additional strategic partners.

TrueLeap reports that the funding will support the large-scale rollout of its "edge AI, integrated learning systems and last-mile broadband across underserved communities."

“The last mile is where most digital transformation efforts break down,” Sandip Bordoloi, CEO and president of TrueLeap, said in a news release. “TrueLeap was built to operate where bandwidth is limited, power is unreliable, and institutions need real systems—not pilots. This round allows us to scale infrastructure that actually works on the ground.”

True Leap works to address the digital divide in education through its AI-powered education, workforce systems and digital services that are designed for underserved and low-connectivity communities.

The company has created infrastructure in Africa, India and rural America. Just this week, it announced an agreement with the City of Kinshasa in the Democratic Republic of Congo to deploy a digital twin platform for its public education system that will allow provincial leaders to manage enrollment, staffing, infrastructure and performance with live data.

“What sets TrueLeap apart is their infrastructure mindset,” Joe Swinbank, General Partner at Joe Swinbank Family Limited Partnership, added in the news release. “They are building the physical and digital rails that allow entire ecosystems to function. The convergence of edge compute, connectivity, and services makes this a compelling global infrastructure opportunity.”

TrueLeap was founded by Bordoloi and Sunny Zhang and developed out of Born Global Ventures, a Houston venture studio focused on advancing immigrant-founded technology. It closed an oversubscribed pre-seed in 2024.