Houston expert: How ChatGPT affects business skills in 2023

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Here's what you should think about before rolling this hot new technology into your business. Photo via Getty Images

The world has been captivated by ChatGPT, an artificial intelligence program that can understand and respond to questions and statements using natural language, just like humans. It has been trained on a large amount of text data and uses this knowledge to generate helpful and informative responses to users.

As great and resourceful as this can be, there are some major aspects about it that can be harmful in a business setting, such as the inability to make personal connections. A sales manager using AI to write sales scripts cannot incorporate the emotional intelligence needed to form a connection. With the switch to AI and loss of this personal touch, the company’s close rate drops significantly, and the sales manager’s effort to find solution may just be to run more numbers in terms of contacts and sales attempts, which usually exacerbates the problem.

Another example of how ChatGPT can hurt your business is by relying on it to generate website and social media content. A business owner that believes ChatGPT will do the “heavy lifting” and grow his or her business is overlooking the importance of creating real and experiential marketing experiences for customers. Business owners can inadvertently spend entire budgets on AI driven social media ands and not have the sales numbers to cover these costs due to their low returns on investments for many industries and keep the business in operation.

The overarching theme, or danger behind ChatGPT, is that people are relying heavily on it to produce their work. After all, relying on technology is part of our human nature. When great technology is introduced, such as email, teleconferencing, AI assisted searching, etc., we rarely ask ‘how can this technology assist me?’ versus ‘how can this technology do things for me?’ The greater the technology, the greater likelihood humans will take the easiest path.

ChatGPT not only affects businesses, but it also applies to education. Teachers are already seeing a drop in math skills as kids carry around calculators. Just wait until next semester when educators are reading thousands of essays written by ChatGPT.

Just as we would hate to see our children deprive themselves of actual skills, the same can be said for our business people. Some of the main issues that arise from the use of ChatGPT are:

Diminishing Rates of Return

When we embrace technology to the point that we no longer put forth effort from a practiced skill set, we can expect to see declining engagement rates, click-through rates and customer loyalty. As of 2023, the online engagement rate has fallen from 5% to 0.06%. Click-through rates are not faring much better with a measly 6.3%. As these numbers continue to fall (which they have every year for the past couple decades now), we continue to just brush it off as this is how business is done.

Aversion in the Marketplace

People are becoming so displeased with technology driven processes (as opposed to technology assisted processes) that they have a strong aversion to companies using it. How many social media ads have prompted you to make a purchase? How many times do you provide a bogus email to a website form? When doing a search, how many times do you scroll to the bottom without looking and hit page two because you know you are not getting any real results on the first page anymore?

Yes, ChatGPT is cool and yes, there are some amazing uses you can implement into your business; however, do not look at it as the answer to any and all business problems. Embrace your craft as a leader and avoid subbing the work out to tech - doing so could cost you everything.

As a business owner myself, I am not opposed to technology. I am all in favor of what technology can do. However, there is no denying that the more we look to technology to do the work for us instead of with us, the more we see a drastic decline in the overall skill set of business people without an increase in business success rates.

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Josh Tolley is the founder of Kingsbridge LLC and is based in Houston.

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Houston researchers develop dissolvable implant for targeted cancer drug delivery

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Researchers at Houston Methodist have developed a biodegradable implant that can be used to safely and consistently deliver drug treatments to tumors and then dissolve without the need for further surgery.

The implant is only the size of a grain of rice, but its potential is staggering. The biodegradable nanofibrous drug-eluting seed (b-NDES) works as a reservoir parked inside a soft tumor, where it can slowly release immune-stimulating drugs over time. This overcomes a consistent problem with drugs such as immune checkpoint inhibitors. Normal systemic administration sees comparatively little of the drug making its way to the tumor, with most of it circulating throughout the body. The b-NDES is like deploying a small guerrilla fighting force embedded in enemy territory, doing maximum damage to the entrenched tumor.

"To improve cancer treatment, we're trying to start a fire inside the tumor itself," Corrine Chua, associate professor in the Center for BioNanoengineering at Houston Methodist Research Institute, said in a news release. "By activating immune cells directly within the tumor microenvironment, those cells can then travel throughout the body and seek out cancer wherever it exists. The b-NDES platform was developed to help keep therapeutic drugs concentrated inside tumors while minimizing exposure to healthy tissues.”

Chua co-led the study with Alessandro Grattoni, chair and director of the Center for BioNanoengineering at Houston Methodist Research Institute.

The study included support from the Nancy Owens Breast Cancer Foundation and the National Institutes of Health/National Cancer Institute.

Chau and Grattoni used preclinical models of triple-negative breast cancer, an aggressive form of cancer that is estrogen receptor-negative, progesterone receptor-negative and HER2-negative. Because of the receptor negativity, some popular treatments like tamoxifen and trastuzumab are ineffective. Chemotherapy has been shown to be the best course of action.

The b-NDES implant is deployed alongside radiation drugs. It keeps the drugs focused on the tumor, reducing the amount of harmful side effects typically seen when drugs are circulated more widely in the body. In 60 percent of the models, tumors were eliminated and did not cause side effects beyond the tumor site. Once the drugs have been deployed, the implant breaks down naturally.

While promising, more research will have to be done to expand use to other tumor types.

"Although the study focused on triple-negative breast cancer models, the approach could have broader applications for solid tumors," Grattoni added in the release. "It could potentially be used in cancers where there is a tumor lesion accessible for placement, including pancreatic or lung cancers."

New Houston platform Same Day Reels launches for on-demand content creation

In The Moment

If an event doesn't happen on Instagram, did it even really happen? In today's social media-driven age of branding and audience engagement, the answer increasingly is no.

Houston entrepreneur Karen De Amat is looking to fill the online content creation needs of companies with her new venture, Same Day Reels, which launched in early August. It will serve as a platform to connect companies and brands with talent that can help turn an event into a viral moment as it is happening.

"Events move quickly, and social media moves even faster,” said De Amat. “Same Day Reels was built to help brands capture the moment while it still matters. We are creating a more efficient way for businesses and creators to work together. Brands need content faster, and creators need more opportunities to turn their talent into real work. Same Day Reels brings those needs together.”

The company is focused on adding livestreams and concurrent short video content to "activations, launches, fundraisers, grand openings, conferences, hospitality experiences, and private celebrations." Such content can significantly increase the visibility of a product or brand according to digital marketing brands like Wyzowl, whose data found 63 percent of people in 2026 prefer to learn about new products via short video.

Packages offered by Same Day Reels will include filming, editing, and publishing content within hours of the targeted event.

De Amat says that her content creation platform will be a way to preserve the excitement of events and launches by enshrining them with immediate social media-driven memories.

“Event content is no longer just something you post after the fact,” De Amat said. “It is part of how people experience, remember and share the moment.”

Previously, De Amat is also the founder and CEO of Social Behavior, an influencer marketing company she launched from her home in 2014. It quickly garnered an array of clients and thrust De Amat into the spotlight, including numerous appearances on Fox 26's The Isiah Factor. Influencer Marketing Hub named her one of the top CEOs of influencer marketing companies in Houston in 2025.

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This article originally appeared on CultureMap.com.

Bristol Myers Squibb to build $2.3B Houston pharma manufacturing campus

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New Jersey-based pharmaceutical giant Bristol Myers Squibb Co. has officially named Houston as the home of its new state-of-the-art manufacturing site.

The 60,000-square-foot facility represents a $2.3 billion investment, according to a news release. It is expected to create 500 skilled jobs and will be located in Houston's Generation Park.

BMS first announced that it was considering Houston among 16 other cities for the facility in May. The new hub will manufacture small molecule, biologic and antibody-drug conjugates and is part of a $40 billion commitment to invest in the United States over five years. Construction is slated to begin next year, with the facility coming online in 2030.

"We're building the domestic manufacturing capabilities needed to deliver the next generation of medicines and support future scientific breakthroughs. Houston and the state of Texas offer the talent, infrastructure, and partnership needed to help bring that vision to life," Christopher Boerner, CEO and board chair of BMS, said in the release.

The new facility will feature a modular, multi-modal design, which will allow the company to reconfigure and add to its manufacturing capabilities over time. BMS says it expects the facility to "(grow) in scale and capability well beyond its opening configuration."

"Our decision to build this state-of-the-art manufacturing campus in Houston, Texas, reflects our confidence in the region’s ability to support a world-class, digitally advanced supply operation,” Karin Shanahan, EVP and chief supply chain and operations officer of BMS, added in the release. “This facility is designed to deliver the speed, quality, and reliability that patients depend on, combining flexible, modular manufacturing with advanced digital capabilities to ensure consistent supply across multiple modalities. It strengthens our ability to operate with resilience and positions us to reliably deliver medicines to patients today while adapting future demands.”

Texas Gov. Greg Abbott shared that the state has granted BMS a $4.89 million Texas Enterprise Fund (TEF) grant for the project. TEF grants, administered by the Texas Economic Development & Tourism Office, support business relocation or expansion projects that create "new, good-paying jobs in the community and attract significant new capital investment to the state." The development is also a qualified project under the Texas Jobs, Energy, Technology, and Innovation (JETI) program.

“Texas is a global hub for life sciences, where today’s innovations shape the future of healthcare,” Abbott said in a news release. “This $2.3 billion investment by Bristol Myers Squibb in the dynamic biotech ecosystem in Houston is a testament to the depth of our skilled workforce and the pipeline of talent coming through our nation-leading technical colleges and research universities. With lower operating costs and easy access to markets across the U.S. and the world, Texas drives affordability for consumers.”

"Bristol Myers Squibb’s announcement is a tremendous win for Texas and the Houston region, further reinforcing our position as a premier destination for life sciences and advanced manufacturing,” added Greater Houston Partnership President and CEO Steve Kean.

Last fall, Eli Lilly and Co. selected Generation Park, a 4,300-acre, master-planned commercial district near Lake Houston, for its $6.5 billion manufacturing plant. More than 300 locations in the U.S. competed for the factory. Read more here.

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