Harris County welcomed more new out-of-state arrivals than any other county in Texas. Getty Images

In the late 1800s through the mid-1950s, New York City's Ellis Island — sitting in the Statue of Liberty's shadow — served as the entry point for millions of new arrivals to the U.S.

Houston doesn't have its own version of Ellis Island, but perhaps it deserves a symbolic one to commemorate the flood of new arrivals from other states.

In 2017, Harris County welcomed more new out-of-state arrivals (81,781) than any other county in Texas, according to a data analysis released December 9 by StorageCafé, a self-storage marketplace.

That influx stands to reason, since Harris County is the state's largest county as measured by population (more than 4 million and counting). Still, it's astounding that Harris County attracted almost as many new arrivals as the entire population of Conroe (87,654 in 2018).

StorageCafé based its analysis on data published last year by the U.S. Census Bureau. The analysis excludes new arrivals from other Texas counties and new arrivals from outside the U.S.

No other county in the Houston metro area appeared in StorageCafé's ranking of the top 10 Texas counties for new arrivals from out of state. That hardly discounts the fact that the entire metro area is witnessing substantial population growth, though.

The Houston area added nearly 1.08 million residents between 2010 and 2018, growing at a rate of 18.2 percent, according to Census Bureau figures cited by the Greater Houston Partnership. From 2017 to 2018 alone, the region's population jumped by 91,689 — the third largest increase in the country — to just shy of 7 million.

To be clear, more than 1 million people didn't pack up and move to the Houston area from 2010 to 2018. Rather, the region's population growth rate comprises arrivals and births stacked up against departures and deaths.

Although the StorageCafé analysis indicates a Texas-leading population spike, Bill Fulton, director of Rice University's Kinder Institute for Urban Research, notes that Harris County has experienced an overall decline in population growth since 2015.

"This is not surprising given the drop in oil prices, which led to economic stagnation in Houston," Fulton tells CultureMap.

Fulton points out that Harris County's population gains don't match the combined growth of the Dallas-Fort Worth area's two biggest counties — Dallas and Tarrant. Dallas County has about 2.6 million residents, while Tarrant County (Fort Worth) has a little over 2 million. That's a total of about 4.6 million, compared with Harris County's nearly 4.7 million residents.

"Don't be deceived into thinking that because Harris County has a much greater population increase than any other county, that, therefore, metro Houston is growing a lot faster than DFW," Fulton says. "If you add the Dallas and Tarrant numbers together, it clearly shows that DFW is still attracting more [newcomers] than Houston."

"The bottom line is: For the past several years, DFW has been growing faster than Houston, and that growth has been driven by [more newcomers] from other states," Fulton adds.

Indeed, grabbing second place in the StorageCafé ranking was Dallas County, with 47,336 new out-of-state arrivals in 2017. And in the No. 3 spot, next-door Tarrant County picked up 44,181 new arrivals. That means Dallas and Tarrant counties drew more than 91,500 new out-of-state residents in 2017, beating the total for Harris County.

Two other DFW counties, Collin and Denton, ranked sixth and seventh, respectively, in StorageCafé's list of the top 10 Texas counties. Collin County saw 24,918 new out-of-state arrivals in 2017, with Denton County at 22,190.

All told, the four DFW counties in Texas' top 10 absorbed 138,625 new out-of-state residents in 2017. By comparison, 138,541 people lived in Denton in 2018, the Census Bureau says.

From 2010 to 2018, Dallas-Fort Worth added more residents — over 1.11 million, or a growth rate of 17.3 percent — than any other major metro area in the country, according to the Census Bureau. In terms of the sheer number of new residents, DFW eclipsed Houston during that period, but Houston held a slight edge for percentage growth.

Bexar County, which anchors the San Antonio metro area, claimed the No. 4 spot in the StorageCafé ranking, attracting 41,062 out-of-state newcomers in 2017.

Just behind it, at No. 5, was Travis County, which anchors the Austin metro area. The StorageCafé data shows 33,939 people relocated to Travis County from out of state in 2017. Rounding out the top 10 was Williamson County (suburban Austin), with 15,712 out-of-state newcomers.

Combined, Travis and Williamson counties gained close to 50,000 out-of-staters in 2017. By comparison, Pflugerville was home to 59,245 residents in 2018, according to the Census Bureau.

Others in the top 10 were El Paso County at No. 8 and Bell County (home of Killeen and Temple) at No. 9.

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This article originally ran on CultureMap.

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Rice launches 'brain economy' initiative at World Economic Forum

brain health

Rice University has launched an initiative that will position “brain capital” as a key asset in the 21st century.

Rice rolled out the Global Brain Economy Initiative on Jan. 21 at the World Economic Forum in Davos, Switzerland.

“This initiative positions brain capital, or brain health and brain skills, at the forefront of global economic development, particularly in the age of artificial intelligence,” the university said in a news release.

The Rice-based initiative, whose partners are the University of Texas Medical Branch in Galveston and the Davos Alzheimer’s Collaborative, aligns with a recent World Economic Forum and McKinsey Health Institute report titled “The Human Advantage: Stronger Brains in the Age of AI,” co-authored by Rice researcher Harris Eyre. Eyre is leading the initiative.

“With an aging population and the rapid transformation of work and society driven by AI, the urgency has never been greater to focus on brain health and build adaptable human skills—both to support people and communities and to ensure long-term economic stability,” says Amy Dittmar, a Rice provost and executive vice president for academic affairs.

This initiative works closely with the recently launched Rice Brain Institute.

In its first year, the initiative will establish a global brain research agenda, piloting brain economy strategies in certain regions, and introducing a framework to guide financial backers and leaders. It will also advocate for public policies tied to the brain economy.

The report from the McKinsey Health Institute and World Economic Forum estimates that advancements in brain health could generate $6.2 trillion in economic gains by 2050.

“Stronger brains build stronger societies,” Eyre says. “When we invest in brain health and brain skills, we contribute to long-term growth, resilience, and shared prosperity.”

Rice Alliance and the Ion leader Brad Burke to retire this summer

lasting legacy

Brad Burke—a Rice University associate vice president who leads the Ion District’s Rice Alliance for Technology and Entrepreneurship and is a prominent figure in Houston’s startup community—is retiring this summer after a 25-year career at the university.

Burke will remain at the Rice Alliance as an adviser until his retirement on June 30.

“Brad’s impact on Rice extends far beyond any single program or initiative. He grew the Rice Alliance from a promising campus initiative into one of the most respected university-based entrepreneurship platforms,” Rice President Reginald DesRoches said in a news release.

During Burke’s tenure, the Rice Business School went from unranked in entrepreneurship to The Princeton Review’s No. 1 graduate entrepreneurship program for the past seven years and a top 20 entrepreneurship program in U.S. News & World Report’s rankings for the past 14 years.

“Brad didn’t just build programs — he built an ecosystem, a culture, and a reputation for Rice that now resonates around the world,” said Peter Rodriguez, dean of the business school. “Through his vision and steady leadership, Rice became a place where founders are taken seriously, ideas are rigorously supported, and entrepreneurship is embedded in the fabric of the university.”

One of Burke’s notable achievements at Rice is the creation of the Rice Business Plan Competition. During his tenure, the competition has grown from nine student teams competing for $10,000 into the world’s largest intercollegiate competition for student-led startups. Today, the annual competition welcomes 42 student-led startups that vie for more than $1 million in prizes.

Away from Rice, Burke has played a key role in cultivating entrepreneurship in the energy sector: He helped establish the Energy Tech Venture Forum along with Houston Energy and Climate Startup Week.

Furthermore, Burke co-founded the Texas University Network for Innovation and Entrepreneurship in 2008 to bolster the entrepreneurship programs at every university in Texas. In 2016, the Rice Alliance assumed leadership of the Global Consortium of Entrepreneurship Centers.

In 2023, Burke received the Trailblazer Award at the 2023 Houston Innovation Awards and was recognized by the Deshpande Foundation for his contributions to innovation and entrepreneurship in higher education.

“Working with an amazing team to build the entrepreneurial ecosystem at Rice, in Houston, and beyond has been the privilege of my career,” Burke said in the release. “It has been extremely gratifying to hear entrepreneurs say our efforts changed their lives, while bringing new innovations to market. The organization is well-positioned to help drive exponential growth across startups, investors, and the entrepreneurial ecosystem.”

Starting April 15, John “JR” Reale Jr. will serve as interim associate vice president at Rice and executive director of the Rice Alliance. He is managing director of the alliance. Reale is co-founder of the Station Houston startup hub and a startup investor. He was also recently named director for startups and investor engagement at the Ion.

“The Rice Alliance has always been about helping founders gain advantages to realize their visions,” Reale said. “Under Brad’s leadership, the Rice Alliance has become a globally recognized platform that is grounded in trust and drives transformational founder outcomes. My commitment is to honor what Brad has built and led while continuing to serve our team and community, deepen relationships and deliver impact.”

Burke joined the Houston Innovators Podcast back in 2022. Listen to the full interview here.

Houston team uses CPRIT funding to develop nanodrug for cancer immunotherapy

cancer research

With a relative five-year survival rate of 50 percent, pancreatic cancer is a diagnosis nobody wants. At 60 percent, the prognosis for lung cancer isn’t much rosier. That’s because both cancers contain regulatory B cells (Bregs), which block the body’s natural immunity, making it harder to fight the enemies within.

Newly popular immunotherapies in a category known as STING agonists may stimulate natural cancer defenses. However, they can also increase Bregs while simultaneously causing significant side effects. But Wei Gao, assistant professor of pharmacology at the University of Houston College of Pharmacy, may have a solution to that conundrum.

Gao and her team have developed Nano-273, a dual-function drug, packaged in an albumin-based particle, that boosts the immune system to help it better fight pancreatic and lung cancers. Gao’s lab recently received a $900,000 grant from the Cancer Prevention and Research Institute of Texas (CPRIT) to aid in fueling her research into the nanodrug.

“Nano-273 both activates STING and blocks PI3Kγ—a pathway that drives Breg expansion, while albumin nanoparticles help deliver the drug directly to immune cells, reducing unwanted side effects,” Gao said in a press release. “This approach reduces harmful Bregs while boosting immune cells that attack cancer, leading to stronger and more targeted anti-tumor responses.”

In studies using models of both pancreatic and lung cancers, Nano-273 has shown great promise with low toxicity. Its best results thus far have involved using the drug in combination with immunotherapy or chemotherapy.

With the CPRIT funds, Gao and her team will be able to charge closer to clinical use with a series of important steps. Those include continuing to test Nano-273 alongside other drugs, including immune checkpoint inhibitors. Safety studies will follow, but with future patients in mind, Gao will also work toward improving her drug’s production, making sure that it’s safe and high-quality every time, so that it is eventually ready for trials.

Gao added: “If successful, this project could lead to a new type of immunotherapy that offers lasting tumor control and improved survival for patients with pancreatic and lung cancers, two diseases that urgently need better treatments."