In a recent survey, more than 20 percent of Houston-area residents said their financial status was worse than it was 12 months earlier. Photo via Getty Images

The region’s economy tops the list of concerns of Houston-area residents surveyed by Rice University’s Kinder Institute for Urban Research.

Respondents in the Kinder Houston Area Survey, which questioned nearly 9,000 residents of Harris, Fort Bend and Montgomery counties, cite the regional economy as the area’s “biggest problem.”

Shrinking confidence in job opportunities and growing household financial pressures fueled the grim economic outlook:

  • The share of residents rating job prospects as “good” or “excellent” fell by more than 25 percentage points, the sharpest single-year decline since the 1980s.
  • Seventy-nine percent of those earning less than $25,000 said they’d be unable to cover an unplanned $400 expense. That was up from 72 percent last year. In the $50,000-to-$99,999 category, the figure was 39 percent, up from 30 percent last year.
  • More than 20 percent of residents said their financial status was worse than it was 12 months earlier.

“These challenges were particularly notable among lower- and middle-earning households,” according to a report about the survey.

Dan Potter, co-director of the institute’s Houston Population Research Center, says the annual survey “provides community leaders and the public with a map of where we’ve been on key issues, where we are now, and what’s of looming importance. It allows everyone to work together toward a better future for our city and our region.”
The annual survey revealed that the percentage of Houston-area residents who had a positive view of the local job market dropped slightly. Photo via Getty Images

Major new Rice study reveals what Houstonians care about most in 2021

Hou cares

Few studies gauge the barometric pressure of the Bayou City like the Kinder Houston Area Survey.

Designed to take the temperature of the general population, the study — now in its 40th year — reveals a Houston citizenry optimistic about its personal futures, per the report.

A little about the study before delving in: The report was conducted by the esteemed Stephen Klineberg, founding director of Rice University's Kinder Institute for Urban Research and emeritus professor of sociology; and Robert Bozick, senior research fellow at the Kinder Institute.

This new survey was unveiled at the Kinder Institute's "Lunch-Out" recent virtual event. Interviews of some 1,051 Harris County adults were conducted between January 18 and March 29 by the National Opinion Research Center at the University of Chicago.

The full report is available online.

The No. 1 concern

Public health concerns, while rarely registering in previous surveys, were cited as the biggest problem facing Houstonians this year, according to a press release. Some 25 percent of respondents cited the pandemic or health-related issues.

Others — 20 percent — pointed to the economy as the biggest problem, that's up from 13 percent last year. Only 14 percent cited crime, and traffic dropped to 13 percent, down from 30 percent last year.

Highlighting a national socioeconomic disparity, 58 percent of Blacks and 66 percent of Hispanics said they had to risk exposure to the coronavirus to keep their jobs during the past year, per the report. That's compared to 41 percent of Asians and only 36 percent of whites.

Additionally, the report notes that Blacks and Hispanics were more likely (at 73 percent and 67 percent, respectively) to know someone who was hospitalized with or died as a result of having COVID-19, compared with whites (57 percent) and Asians (40 percent).

Mental health issues have arisen as a serious problem in equal numbers across ethnic communities. More than 50 percent of respondents — in all four groups — reported feeling more stress and experiencing more emotional problems during the past year, compared with 2020.

Jobs and the economy

Though Houston is an opportunity city, the Kinder Survey revealed that the percentage of Houston-area residents who had a positive view of the local job market dropped slightly, to 61 percent this year from 68 percent in 2020.

A mere 21 percent reported their economic situations were getting better, down from 34 percent in 2020. Notably — for the first time in the 40 years — of the survey, more respondents (25 percent) said their financial situations were getting worse than getting better.

Blacks and Hispanics were also more likely than Asians and whites to have experienced a loss of income and to have received help from government programs in the past year.

Race relations, immigration, and inequity

Positive ratings of relations among ethnic groups in the Houston area declined across the board, especially among Blacks. Whites and Hispanics were significantly more likely than in previous years to agree that Blacks are still a long way from having the same opportunities in life as whites.

The number of people who said the criminal justice system is biased against Blacks increased to 54 percent from 32 percent in 2015, when the question was last asked, per a release.

Weather, religion, and politics

Area residents were less likely than in previous surveys to say it's virtually certain the region will experience more severe storms in coming years (59 percent in 2021, compared with 81 percent in 2018 and 2020).

The number of religious Houstonians continues to decline, with more people than ever indicating they are not part of any faith tradition (22 percent today, compared with 8 percent in 2008) and do not consider religion to be an important part of their lives (26 percent, compared with 10 percent in 2008), per the study.

Meanwhile, 45 percent of those surveyed said they felt closer to the Democratic Party this year, while only 25 percent voiced support for the Republican Party.

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This article originally ran on CultureMap.

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Houston brain health co. secures $6.5M for rare disease study

neuro funding

Houston-based Goldenrod Therapeutics, part of Fannin Partners' portfolio, has announced the initial close of a $6.5 million series seed preferred stock round.

The round was led by Ataxia Ventures and an affiliate of Fannin, according to a news release.

Goldenrod Therapeutics plans to use the funding to support manufacturing, formulation optimization, IND-enabling studies and a Phase I study of its drug to treat brain inflammation, known as 11h.

The study will consider how 11h, which blocks the enzyme PDE4, could treat Friedreich’s ataxia (FA), a rare genetic disease that affects movement, speech and balance. To date, other PDE4 inhibitors have proven to regulate neuroinflammation and neuronal signaling, but have had adverse gastrointestinal side effects or have not reached enough of the central nervous system, according to Goldenrod.

The company says its 11h is expected to have "broad applicability" with limited emetric side effects.

“Our 11h program is a next-generation, orally bioavailable, brain-penetrant PDE4 inhibitor, where researchers overcame longstanding limitations associated with earlier PDE4 inhibitors," Dr. Dev Chatterjee, CEO of Goldenrod, said in the news release. "We believe this creates the potential for a best-in-class therapy for Friedreich’s Ataxia and a potential foundation for development across multiple neurodegenerative and neuroinflammatory disorders.”

11h was first developed at the University of Nebraska Medical Center (UNeMed). Houston-based Fannin Partners in-licensed the product 2020 and landed SBIR Phase I funding to support its initial development for opioid use disorder soon after.

Goldenrod has also received funding to study 11h's effectiveness for multiple sclerosis, methamphetamine addiction and cocaine addiction.

Goldenrod says it is developing 11h to target a variety of neurological and inflammatory conditions, including Alzheimer's disease, multiple sclerosis, ALS, substance use disorders, Batten disease, pain and traumatic brain injury.

27 Houston companies make Fortune 500 for 2026, led by energy giants

Houston HQs

Editor's note: This article has been updated to correct the number of companies based in the Dallas-Fort Worth area.

Houston is a giant among U.S. hubs for corporate headquarters.

The 2026 Fortune 500 lists 27 companies based in the Houston area, with many energy companies claiming top spots. Houston ties with Chicago for the second-most Fortune 500 headquarters, preceded only by New York City (53). Dallas-Fort Worth is home to 24 Fortune 500 headquarters.

Texas leads the nation for Fortune 500 headquarters (57), with California in the No. 2 spot and New York at No. 3.

“Texas is the undisputed headquarters of headquarters,” Gov. Greg Abbott said in a news release. “The world’s leading businesses invest with confidence in Texas because of our welcoming business climate, predictable regulatory environment, and skilled and growing workforce. People and businesses are choosing Texas because Texas works.”

The 2026 Fortune 500 ranks the largest U.S. corporations based on revenue in fiscal year 2025.

Here’s a rundown of the 27 Fortune 500 companies based in the Houston area.

  • No. 9 ExxonMobil
  • No. 21 Chevron
  • No. 29 Phillips 66
  • No.55 Sysco
  • No. 75 ConocoPhillips
  • No. 89 Enterprise Products Partners
  • No. 103 Plains GP Holdings
  • No. 133 Hewlett Packard Enterprise
  • No. 149 NRG Energy
  • No. 157 Quanta Services
  • No. 164 Baker Hughes
  • No. 173 Occidental Petroleum
  • No. 179 Waste Management
  • No. 201 EOG Resources
  • No. 204 Group 1 Automotive
  • No. 207 Halliburton
  • No. 223 Cheniere Energy
  • No. 236 Corebridge Financial
  • No. 262 Targa Resources
  • No. 266 Kinder Morgan
  • No. 388 Westlake
  • No. 435 CenterPoint Energy
  • No. 438 APA
  • No. 440 Comfort Systems USA
  • No. 455 NOV
  • No. 488 KBR
  • No. 496 Coterra Energy. Oklahoma City, Oklahoma-based Devon Energy and Houston-based Coterra Energy merged in early May, with the combined company retaining the Devon Energy name and the Houston headquarters.

The Greater Houston Partnership notes the Houston area soon will welcome its 28th Fortune 500 company. Expand Energy (formerly Chesapeake Energy), appearing at No. 362 on the 2026 list, says it’s moving its headquarters from Oklahoma City to Spring this year.

As the natural gas producer prepares to relocate to Texas, it’s hunting for a new leader. Nick Dell’Osso stepped down as president and CEO earlier this year. Board Chairman Michael Wichterich is interim president and CEO.

Dell’Osso became president and CEO of Oklahoma City-based Gulfport Energy effective May 28.

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This article first appeared on EnergyCapitalHTX.com.