In the latest round up of Houston innovation news you may have missed, student startups selected for a summer program, Texas might be among the best states for nurses, and more. Photo by Scott Halleran/Getty Images

It's been a busy season for the Houston innovation ecosystem, and for this reason, local startup and tech news may have fallen through some of the cracks.

In this roundup of short stories within Houston innovation, a software startup is focusing on diversity and inclusion, an angel network has a new partner organization, a Houston innovator is playing a major role in ESG, and more.

GoCo hosts its first-ever DEI Hackathon

GoCo is hosting its first hackathon. Photo via Getty Images

GoCo.io, a Houston-based human resources software-as-a-service company, is hosting its first hackathon for diversity, equity, and inclusion begining today, May 6, and continuing through tomorrow, May 7.

GoCo's entire staff is going to work for over 36 hours to build solutions aimed at promoting diversity, equity, and inclusion for small businesses.

"Building technology to help HR make a difference in the workplace is what we're all about at GoCo," says Allie Collins, head of GoCo's DEI Task Force, in a news release. "HR professionals are being called upon to make profound and meaningful changes to combat racism and inequities. We're hosting this event because our whole team is passionate about creating apps and resources to facilitate that change."

The competitors will be on teams and will present their projects on Monday, May 10, for a panel of judges.

Rice Alliance backs diversity-focused angel investment network

Maria Maso, CEO of baMa, has announced Rice Alliance as a partner organization. Photo courtesy of Nijalon Dunn

The Rice Alliance for Technology and Entrepreneurship has become a baMa champion of diversity for angel network baMa, or the Business Angel Minority Association.

"Rice Alliance aims to foster an innovative and entrepreneurial culture that not only values differences, but also elevates them as sources of strength and innovation," says Rice Alliance's managing director, Brad Burke, in a news release.

According to the release, baMa will help to introduce Rice to more diverse businesses. The angel network has already tapped into Rice's ecosystem with the $50,000 investment prize baMa awarded during the Rice Business Plan Competition in March.

"Diversity and education go hand by hand so counting with the support of Rice Alliance is a huge step in order to accomplish baMa's goal: close the investment gap in minority-led startups," says baMa CEO, Maria Maso.

Topl named to ESG council

Kim Raath will serve on CNBC's ESG Council. Photo courtesy of Topl

Kim Raath, CEO of Houston-based blockchain company, Topl, has announced that she has been invited to join the CNBC's ESG Council. She was selected among execs from large corporations like companies such as The HEINEKEN Company, Nestlé, IHG Hotels & Resorts, Nissan Motor Corporation, Bain & Company, Credit Suisse, and more.

"As a young startup, this is one of our most exciting milestones. Sitting at the table with industry leaders is great momentum for both Topl's success and our larger ESG mission," Raath writes in Topl's newsletter. "Traceable transparency in supply chains is a game changer for global commerce, and now Topl can learn from and collaborate with multinational corporations. This opportunity will help position our purpose-built blockchain as a solution to solve some of the biggest and most critical problems our world faces, and as we strive to build a more sustainable future for all."

The council is a roundtable of 30 business leaders across industries focused on the challenges posed by sustainability — and the strategies needed to overcome them, according to Raath.

Is Texas a good state for nurses?

A new report ranks states based on their opportunities and friendly environment for nurses. Photo via Getty Images

The Lone Star State's nursing industry was put to the test for a new report from WalletHub, a personal financial website. The study compared all 50 states based on opportunity and competition and work environment. Texas ranked No. 12 overall.

Ranked solely on opportunity and competition — which included evaluating salary, schools, nurses per 1,000 residents, and more — Texas came in at No. 11.

The top states on the list were Arizona, Washington, and Nevada, respectively.

Rice University announces OwlSpark's ninth cohort

Meet the 10 student startups that are joining the OwlSpark family this summer. Photo courtesy of OwlSpark

Rice University's student startup accelerator has named 10 startup teams to its ninth cohort, which kicks off later this month. OwlSpark's 2021 cohort includes teams from across industries — hospitality, sports, oil and gas, consumer, staffing, automotive and more. According to a release from Rice, these are the companies selected:

  • Capybara - a networked platform that facilitates the company-to-company transfer of IT employees with similar skill sets (for example, software developers)
  • ChckMate – a data-driven platform designed to improve customer dining experiences, drive loyalty and increase revenue
  • GatherX Analytics – an AI software platform that predicts location and quantity of hydrocarbon liquid dropout for use by the upstream oil and gas industry
  • HARK – an easy-to-use app designed to significantly enhance the way in which neurodivergent or cognitively impaired individuals communicate real-time with caregivers and loved ones
  • Home Maintainer - a comprehensive solution for homeowners to manage and simplify home maintenance and efficiency
  • OneLab - a robust cloud-based repository designed for effective organization and easy access to a body of data on a specific area of research
  • Oversox– waterproof, durable, sock-like coverings designed to easily slip over the outside of a shoe for use by the serious hiker
  • rutd – an enterprise software and mobile application that provides immediate, actionable, suicide prevention resources to military veterans and family members
  • Tailer – a training platform and sales tool for electric vehicle dealerships and sales personnel
  • Yellow Saffron Labs – a risk analysis platform that gathers datasets from peer-reviewed scientific publications for use by organizations to observe industry trends or upcoming scientific disruptions or discoveries

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Houston scientists develop breakthrough AI-driven process to design, decode genetic circuits

biotech breakthrough

Researchers at Rice University have developed an innovative process that uses artificial intelligence to better understand complex genetic circuits.

A study, published in the journal Nature, shows how the new technique, known as “Combining Long- and Short-range Sequencing to Investigate Genetic Complexity,” or CLASSIC, can generate and test millions of DNA designs at the same time, which, according to Rice.

The work was led by Rice’s Caleb Bashor, deputy director for the Rice Synthetic Biology Institute and member of the Ken Kennedy Institute. Bashor has been working with Kshitij Rai and Ronan O’Connell, co-first authors on the study, on the CLASSIC for over four years, according to a news release.

“Our work is the first demonstration that you can use AI for designing these circuits,” Bashor said in the release.

Genetic circuits program cells to perform specific functions. Finding the circuit that matches a desired function or performance "can be like looking for a needle in a haystack," Bashor explained. This work looked to find a solution to this long-standing challenge in synthetic biology.

First, the team developed a library of proof-of-concept genetic circuits. It then pooled the circuits and inserted them into human cells. Next, they used long-read and short-read DNA sequencing to create "a master map" that linked each circuit to how it performed.

The data was then used to train AI and machine learning models to analyze circuits and make accurate predictions for how untested circuits might perform.

“We end up with measurements for a lot of the possible designs but not all of them, and that is where building the (machine learning) model comes in,” O’Connell explained in the release. “We use the data to train a model that can understand this landscape and predict things we were not able to generate data on.”

Ultimately, the researchers believe the circuit characterization and AI-driven understanding can speed up synthetic biology, lead to faster development of biotechnology and potentially support more cell-based therapy breakthroughs by shedding new light on how gene circuits behave, according to Rice.

“We think AI/ML-driven design is the future of synthetic biology,” Bashor added in the release. “As we collect more data using CLASSIC, we can train more complex models to make predictions for how to design even more sophisticated and useful cellular biotechnology.”

The team at Rice also worked with Pankaj Mehta’s group in the department of physics at Boston University and Todd Treangen’s group in Rice’s computer science department. Research was supported by the National Institutes of Health, Office of Naval Research, the Robert J. Kleberg Jr. and Helen C. Kleberg Foundation, the American Heart Association, National Library of Medicine, the National Science Foundation, Rice’s Ken Kennedy Institute and the Rice Institute of Synthetic Biology.

James Collins, a biomedical engineer at MIT who helped establish synthetic biology as a field, added that CLASSIC is a new, defining milestone.

“Twenty-five years ago, those early circuits showed that we could program living cells, but they were built one at a time, each requiring months of tuning,” said Collins, who was one of the inventors of the toggle switch. “Bashor and colleagues have now delivered a transformative leap: CLASSIC brings high-throughput engineering to gene circuit design, allowing exploration of combinatorial spaces that were previously out of reach. Their platform doesn’t just accelerate the design-build-test-learn cycle; it redefines its scale, marking a new era of data-driven synthetic biology.”

Axiom Space wins NASA contract for fifth private mission, lands $350M in financing

ready for takeoff

Editor's note: This story has been updated to include information about Axiom's recent funding.

Axiom Space, a Houston-based space infrastructure company that’s developing the first commercial space station, has forged a deal with NASA to carry out the fifth civilian-staffed mission to the International Space Station.

Axiom Mission 5 is scheduled to launch in January 2027, at the earliest, from NASA’s Kennedy Space Center in Florida. The crew of non-government astronauts is expected to spend up to 14 days docked at the International Space Station (ISS). Various science and research activities will take place during the mission.

The crew for the upcoming mission hasn’t been announced. Previous Axiom missions were commanded by retired NASA astronauts Michael López-Alegría, the company’s chief astronaut, and Peggy Whitson, the company’s vice president of human spaceflight.

“All four previous [Axiom] missions have expanded the global community of space explorers, diversifying scientific investigations in microgravity, and providing significant insight that is benefiting the development of our next-generation space station, Axiom Station,” Jonathan Cirtain, president and CEO of Axiom, said in a news release.

As part of Axiom’s new contract with NASA, Voyager Technologies will provide payload services for Axiom’s fifth mission. Voyager, a defense, national security, and space technology company, recently announced a four-year, $24.5 million contract with NASA’s Johnson Space Center in Houston to provide mission management services for the ISS.

Axiom also announced today, Feb. 12, that it has secured $350 million in a financing round led by Type One Ventures and Qatar Investment Authority.

The company shared in a news release that the funding will support the continued development of its commercial space station, known as Axiom Station, and the production of its Axiom Extravehicular Mobility Unit (AxEMU) under its NASA spacesuit contract.

NASA awarded Axiom a contract in January 2020 to create Axiom Station. The project is currently underway.

"Axiom Space isn’t just building hardware, it’s building the backbone of humanity’s next era in orbit," Tarek Waked, Founding General Partner at Type One Ventures, said in a news release. "Their rare combination of execution, government trust, and global partnerships positions them as the clear successor-architect for life after the ISS. This is how the United States continues to lead in space.”

Houston edtech company closes oversubscribed $3M seed round

fresh funding

Houston-based edtech company TrueLeap Inc. closed an oversubscribed seed round last month.

The $3.3 million round was led by Joe Swinbank Family Limited Partnership, a venture capital firm based in Houston. Gamper Ventures, another Houston firm, also participated with additional strategic partners.

TrueLeap reports that the funding will support the large-scale rollout of its "edge AI, integrated learning systems and last-mile broadband across underserved communities."

“The last mile is where most digital transformation efforts break down,” Sandip Bordoloi, CEO and president of TrueLeap, said in a news release. “TrueLeap was built to operate where bandwidth is limited, power is unreliable, and institutions need real systems—not pilots. This round allows us to scale infrastructure that actually works on the ground.”

True Leap works to address the digital divide in education through its AI-powered education, workforce systems and digital services that are designed for underserved and low-connectivity communities.

The company has created infrastructure in Africa, India and rural America. Just this week, it announced an agreement with the City of Kinshasa in the Democratic Republic of Congo to deploy a digital twin platform for its public education system that will allow provincial leaders to manage enrollment, staffing, infrastructure and performance with live data.

“What sets TrueLeap apart is their infrastructure mindset,” Joe Swinbank, General Partner at Joe Swinbank Family Limited Partnership, added in the news release. “They are building the physical and digital rails that allow entire ecosystems to function. The convergence of edge compute, connectivity, and services makes this a compelling global infrastructure opportunity.”

TrueLeap was founded by Bordoloi and Sunny Zhang and developed out of Born Global Ventures, a Houston venture studio focused on advancing immigrant-founded technology. It closed an oversubscribed pre-seed in 2024.