In the latest round up of Houston innovation news you may have missed, student startups selected for a summer program, Texas might be among the best states for nurses, and more. Photo by Scott Halleran/Getty Images

It's been a busy season for the Houston innovation ecosystem, and for this reason, local startup and tech news may have fallen through some of the cracks.

In this roundup of short stories within Houston innovation, a software startup is focusing on diversity and inclusion, an angel network has a new partner organization, a Houston innovator is playing a major role in ESG, and more.

GoCo hosts its first-ever DEI Hackathon

GoCo is hosting its first hackathon. Photo via Getty Images

GoCo.io, a Houston-based human resources software-as-a-service company, is hosting its first hackathon for diversity, equity, and inclusion begining today, May 6, and continuing through tomorrow, May 7.

GoCo's entire staff is going to work for over 36 hours to build solutions aimed at promoting diversity, equity, and inclusion for small businesses.

"Building technology to help HR make a difference in the workplace is what we're all about at GoCo," says Allie Collins, head of GoCo's DEI Task Force, in a news release. "HR professionals are being called upon to make profound and meaningful changes to combat racism and inequities. We're hosting this event because our whole team is passionate about creating apps and resources to facilitate that change."

The competitors will be on teams and will present their projects on Monday, May 10, for a panel of judges.

Rice Alliance backs diversity-focused angel investment network

Maria Maso, CEO of baMa, has announced Rice Alliance as a partner organization. Photo courtesy of Nijalon Dunn

The Rice Alliance for Technology and Entrepreneurship has become a baMa champion of diversity for angel network baMa, or the Business Angel Minority Association.

"Rice Alliance aims to foster an innovative and entrepreneurial culture that not only values differences, but also elevates them as sources of strength and innovation," says Rice Alliance's managing director, Brad Burke, in a news release.

According to the release, baMa will help to introduce Rice to more diverse businesses. The angel network has already tapped into Rice's ecosystem with the $50,000 investment prize baMa awarded during the Rice Business Plan Competition in March.

"Diversity and education go hand by hand so counting with the support of Rice Alliance is a huge step in order to accomplish baMa's goal: close the investment gap in minority-led startups," says baMa CEO, Maria Maso.

Topl named to ESG council

Kim Raath will serve on CNBC's ESG Council. Photo courtesy of Topl

Kim Raath, CEO of Houston-based blockchain company, Topl, has announced that she has been invited to join the CNBC's ESG Council. She was selected among execs from large corporations like companies such as The HEINEKEN Company, Nestlé, IHG Hotels & Resorts, Nissan Motor Corporation, Bain & Company, Credit Suisse, and more.

"As a young startup, this is one of our most exciting milestones. Sitting at the table with industry leaders is great momentum for both Topl's success and our larger ESG mission," Raath writes in Topl's newsletter. "Traceable transparency in supply chains is a game changer for global commerce, and now Topl can learn from and collaborate with multinational corporations. This opportunity will help position our purpose-built blockchain as a solution to solve some of the biggest and most critical problems our world faces, and as we strive to build a more sustainable future for all."

The council is a roundtable of 30 business leaders across industries focused on the challenges posed by sustainability — and the strategies needed to overcome them, according to Raath.

Is Texas a good state for nurses?

A new report ranks states based on their opportunities and friendly environment for nurses. Photo via Getty Images

The Lone Star State's nursing industry was put to the test for a new report from WalletHub, a personal financial website. The study compared all 50 states based on opportunity and competition and work environment. Texas ranked No. 12 overall.

Ranked solely on opportunity and competition — which included evaluating salary, schools, nurses per 1,000 residents, and more — Texas came in at No. 11.

The top states on the list were Arizona, Washington, and Nevada, respectively.

Rice University announces OwlSpark's ninth cohort

Meet the 10 student startups that are joining the OwlSpark family this summer. Photo courtesy of OwlSpark

Rice University's student startup accelerator has named 10 startup teams to its ninth cohort, which kicks off later this month. OwlSpark's 2021 cohort includes teams from across industries — hospitality, sports, oil and gas, consumer, staffing, automotive and more. According to a release from Rice, these are the companies selected:

  • Capybara - a networked platform that facilitates the company-to-company transfer of IT employees with similar skill sets (for example, software developers)
  • ChckMate – a data-driven platform designed to improve customer dining experiences, drive loyalty and increase revenue
  • GatherX Analytics – an AI software platform that predicts location and quantity of hydrocarbon liquid dropout for use by the upstream oil and gas industry
  • HARK – an easy-to-use app designed to significantly enhance the way in which neurodivergent or cognitively impaired individuals communicate real-time with caregivers and loved ones
  • Home Maintainer - a comprehensive solution for homeowners to manage and simplify home maintenance and efficiency
  • OneLab - a robust cloud-based repository designed for effective organization and easy access to a body of data on a specific area of research
  • Oversox– waterproof, durable, sock-like coverings designed to easily slip over the outside of a shoe for use by the serious hiker
  • rutd – an enterprise software and mobile application that provides immediate, actionable, suicide prevention resources to military veterans and family members
  • Tailer – a training platform and sales tool for electric vehicle dealerships and sales personnel
  • Yellow Saffron Labs – a risk analysis platform that gathers datasets from peer-reviewed scientific publications for use by organizations to observe industry trends or upcoming scientific disruptions or discoveries

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Houston brain health co. secures $6.5M for rare disease study

neuro funding

Houston-based Goldenrod Therapeutics, part of Fannin Partners' portfolio, has announced the initial close of a $6.5 million series seed preferred stock round.

The round was led by Ataxia Ventures and an affiliate of Fannin, according to a news release.

Goldenrod Therapeutics plans to use the funding to support manufacturing, formulation optimization, IND-enabling studies and a Phase I study of its drug to treat brain inflammation, known as 11h.

The study will consider how 11h, which blocks the enzyme PDE4, could treat Friedreich’s ataxia (FA), a rare genetic disease that affects movement, speech and balance. To date, other PDE4 inhibitors have proven to regulate neuroinflammation and neuronal signaling, but have had adverse gastrointestinal side effects or have not reached enough of the central nervous system, according to Goldenrod.

The company says its 11h is expected to have "broad applicability" with limited emetric side effects.

“Our 11h program is a next-generation, orally bioavailable, brain-penetrant PDE4 inhibitor, where researchers overcame longstanding limitations associated with earlier PDE4 inhibitors," Dr. Dev Chatterjee, CEO of Goldenrod, said in the news release. "We believe this creates the potential for a best-in-class therapy for Friedreich’s Ataxia and a potential foundation for development across multiple neurodegenerative and neuroinflammatory disorders.”

11h was first developed at the University of Nebraska Medical Center (UNeMed). Houston-based Fannin Partners in-licensed the product 2020 and landed SBIR Phase I funding to support its initial development for opioid use disorder soon after.

Goldenrod has also received funding to study 11h's effectiveness for multiple sclerosis, methamphetamine addiction and cocaine addiction.

Goldenrod says it is developing 11h to target a variety of neurological and inflammatory conditions, including Alzheimer's disease, multiple sclerosis, ALS, substance use disorders, Batten disease, pain and traumatic brain injury.

27 Houston companies make Fortune 500 for 2026, led by energy giants

Houston HQs

Editor's note: This article has been updated to correct the number of companies based in the Dallas-Fort Worth area.

Houston is a giant among U.S. hubs for corporate headquarters.

The 2026 Fortune 500 lists 27 companies based in the Houston area, with many energy companies claiming top spots. Houston ties with Chicago for the second-most Fortune 500 headquarters, preceded only by New York City (53). Dallas-Fort Worth is home to 24 Fortune 500 headquarters.

Texas leads the nation for Fortune 500 headquarters (57), with California in the No. 2 spot and New York at No. 3.

“Texas is the undisputed headquarters of headquarters,” Gov. Greg Abbott said in a news release. “The world’s leading businesses invest with confidence in Texas because of our welcoming business climate, predictable regulatory environment, and skilled and growing workforce. People and businesses are choosing Texas because Texas works.”

The 2026 Fortune 500 ranks the largest U.S. corporations based on revenue in fiscal year 2025.

Here’s a rundown of the 27 Fortune 500 companies based in the Houston area.

  • No. 9 ExxonMobil
  • No. 21 Chevron
  • No. 29 Phillips 66
  • No.55 Sysco
  • No. 75 ConocoPhillips
  • No. 89 Enterprise Products Partners
  • No. 103 Plains GP Holdings
  • No. 133 Hewlett Packard Enterprise
  • No. 149 NRG Energy
  • No. 157 Quanta Services
  • No. 164 Baker Hughes
  • No. 173 Occidental Petroleum
  • No. 179 Waste Management
  • No. 201 EOG Resources
  • No. 204 Group 1 Automotive
  • No. 207 Halliburton
  • No. 223 Cheniere Energy
  • No. 236 Corebridge Financial
  • No. 262 Targa Resources
  • No. 266 Kinder Morgan
  • No. 388 Westlake
  • No. 435 CenterPoint Energy
  • No. 438 APA
  • No. 440 Comfort Systems USA
  • No. 455 NOV
  • No. 488 KBR
  • No. 496 Coterra Energy. Oklahoma City, Oklahoma-based Devon Energy and Houston-based Coterra Energy merged in early May, with the combined company retaining the Devon Energy name and the Houston headquarters.

The Greater Houston Partnership notes the Houston area soon will welcome its 28th Fortune 500 company. Expand Energy (formerly Chesapeake Energy), appearing at No. 362 on the 2026 list, says it’s moving its headquarters from Oklahoma City to Spring this year.

As the natural gas producer prepares to relocate to Texas, it’s hunting for a new leader. Nick Dell’Osso stepped down as president and CEO earlier this year. Board Chairman Michael Wichterich is interim president and CEO.

Dell’Osso became president and CEO of Oklahoma City-based Gulfport Energy effective May 28.

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This article first appeared on EnergyCapitalHTX.com.