The four volunteer crew members spent more than 12 months inside NASA's first simulated Mars environment at Johnson Space Center in Houston. Photo via NASA

The crew of a NASA mission to Mars emerged from their craft after a yearlong voyage that never left Earth.

The four volunteer crew members spent more than 12 months inside NASA's first simulated Mars environment at Johnson Space Center in Houston, coming out of the artificial alien enviroment Saturday around 5 p.m.

Kelly Haston, Anca Selariu, Ross Brockwell and Nathan Jones entered the 3D-printed habitat on June 25, 2023, as the maiden crew of the space agency's Crew Health and Performance Exploration Analog project.

Haston, the mission commander, began with a simple, “Hello.”

“It’s actually just so wonderful to be able to say ‘hello’ to you all,” she said.

Jones, a physician and the mission medical officer, said their 378 days in confinement “went by quickly.”

The quartet lived and worked inside the space of 1,700 square feet (157 square meters) to simulate a mission to the red planet, the fourth from the sun and a frequent focus of discussion among scientists and sci-fi fans alike concerning a possible voyage taking humans beyond our moon.

The first CHAPEA crew focused on establishing possible conditions for future Mars operations through simulated spacewalks, dubbed “Marswalks,” as well as growing and harvesting vegetables to supplement their provisions and maintaining the habitat and their equipment.

They also worked through challenges a real Mars crew would be expected to experience including limited resources, isolation and delays in communication of up to 22 minutes with their home planet on the other side of the habitat's walls, NASA said.

Two additional CHAPEA missions are planned and crews will continue conducting simulated spacewalks and gathering data on factors related to physical and behavioral health and performance, NASA said.

Steve Koerner, deputy director of Johnson Space Center, said most of the first crew's experimentation focused on nutrition and how that affected their performance. The work was “crucial science as we prepare to send people on to the red planet,” he said.

“They've been separated from their families, placed on a carefully prescribed meal plan and undergone a lot of observation,” Koerner said.

“Mars is our goal,” he said, calling the project an important step in America's intent to be a leader in the global space exploration effort.

Emerging after a knock on the habitat's door by Kjell Lindgren, an astronaut and the deputy director of flight operations, the four volunteers spoke of the gratitude they had for each other and those who waited patiently outside, as well as lessons learned about a prospective manned mission to Mars and life on Earth.

Brockwell, the crew's flight engineer, said the mission showed him the importance of living sustainably for the benefit of everyone on Earth.

“I’m very grateful to have had this incredible opportunity to live for a year within the spirit of planetary adventure towards an exciting future, and I’m grateful for the chance to live the idea that we must utilise resources no faster than they can be replenished and produce waste no faster than they can be processed back into resources," Brockwell said.

“We cannot live, dream, create or explore on any significant timeframe if we don’t live these principles, but if we do, we can achieve and sustain amazing and inspiring things like exploring other worlds," he said.

Science officer Anca Selariu said she had been asked many times why there is a fixation on Mars.

“Why go to Mars? Because it’s possible,” she said. "Because space can unite and bring out the best in us. Because it’s one defining step that ‘Earthlings’ will take to light the way into the next centuries.”

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German biotech co. to relocate to Houston thanks to $4.75M CPRIT grant

money moves

Armed with a $4.75 million grant from the Cancer Prevention and Research Institute of Texas, a German biotech company will relocate to Houston to work on developing a cancer medicine that fights solid tumors.

Eisbach Bio is conducting a clinical trial of its EIS-12656 therapy at Houston’s MD Anderson Cancer Center. In September, the company announced its first patient had undergone EIS-12656 treatment. EIS-12656 works by suppressing cancer-related genome reorganization generated by DNA.

The funding from the cancer institute will support the second phase of the EIS-12656 trial, focusing on homologous recombination deficiency (HRD) tumors.

“HRD occurs when a cell loses its ability to repair double-strand DNA breaks, leading to genomic alterations and instability that can contribute to cancerous tumor growth,” says the institute.

HRD is a biomarker found in most advanced stages of ovarian cancer, according to Medical News Today. DNA constantly undergoes damage and repairs. One of the repair routes is the

homologous recombination repair (HRR) system.

Genetic mutations, specifically those in the BCRA1 and BCRA1 genes, cause an estimated 10 percent of cases of ovarian cancer, says Medical News Today.

The Cancer Prevention and Research Institute of Texas (CPRIT) says the Eisbach Bio funding will bolster the company’s “transformative approach to HRD tumor therapy, positioning Texas as a hub for innovative cancer treatments while expanding clinical options for HRD patients.”

The cancer institute also handed out grants to recruit several researchers to Houston:

  • $2 million to recruit Norihiro Goto from the Massachusetts Institute of Technology to MD Anderson.
  • $2 million to recruit Xufeng Chen from New York University to MD Anderson.
  • $2 million to recruit Xiangdong Lv from MD Anderson to the University of Texas Health Science Center at Houston.

In addition, the institute awarded:

  • $9,513,569 to Houston-based Marker Therapeutics for a first-phase study to develop T cell-based immunotherapy for treatment of metastatic pancreatic cancer.
  • $2,499,990 to Lewis Foxhall of MD Anderson for a colorectal cancer screening program.
  • $1,499,997 to Abigail Zamorano of the University of Texas Health Science Center at Houston for a cervical cancer screening program.
  • $1,497,342 to Jennifer Minnix of MD Anderson for a lung cancer screening program in Northeast Texas.
  • $449,929 to Roger Zoorob of the Baylor College of Medicine for early prevention of lung cancer.

On November 20, the Cancer Prevention and Research Institute granted funding of $89 million to an array of people and organizations involved in cancer prevention and research.

West Coast innovation organization unveils new location in Houston suburb to boost Texas tech ecosystem

plugging in

Leading innovation platform Plug and Play announced the opening of its new flagship Houston-area location in Sugar Land, which is its fourth location in Texas.

Plug and Play has accelerated over 2,700 startups globally last year with corporate partners that include Dell Technologies, Daikin, Microsoft, LG Chem, Shell, and Mercedes. The company’s portfolio includes PayPal, Dropbox, LendingClub, and Course Hero, with 8 percent of the portfolio valued at over $100 million.

The deal, which facilitated by the Sugar Land Office of Economic Development and Tourism, will bring a new office for the organization to Sugar Land Town Square with leasing and hiring between December and January. The official launch is slated for the first quarter of 2025, and will feature 15 startups announced on Selection Day.

"By expanding to Sugar Land, we’re creating a space where startups can access resources, build partnerships, and scale rapidly,” VP Growth Strategy at Plug and Play Sherif Saadawi says in a news release. “This location will help fuel Texas' innovation ecosystem, providing entrepreneurs with the tools and networks they need to drive real-world impact and contribute to the state’s technological and economic growth."

Plug and Play plans to hire four full-time equivalent employees and accelerate two startup batches per year. The focus will be on “smart cities,” which include energy, health, transportation, and mobility sectors. One Sugar Land City representative will serve as a board member.

“We are excited to welcome Plug and Play to Sugar Land,” Mayor of Sugar Land Joe Zimmerma adds. “This investment will help us connect with corporate contacts and experts in startups and businesses that would take us many years to reach on our own. It allows us to create a presence, attract investments and jobs to the city, and hopefully become a base of operations for some of these high-growth companies.”

The organization originally entered the Houston market in 2019 and now has locations in Bryan/College Station, Frisco, and Cedar Park in Texas.