Through the project, the UH-led team will use AI can to address issues relating to the "procurement, distribution, access, and utilization of food resources in underserved communities." Photo via uh.edu

The University of Houston announced this month that it will use funds from the National Science Foundation to develop an artificial intelligence program that aims to help food-insecure Texans and eliminate inefficiencies within the food charity system.

The program is backed by a $750,000 grant from the NSF's Convergence Accelerator, which focuses on challenges related to food , nutrition and agriculture. UH's project was among 16 others in the country that received a total of $11 million from the accelerator, which were announced late last year.

The research team from UH includes Norma Olvera, professor of education and a USDA E. Kika de la Garza Fellow; Elizabeth Anderson-Fletcher, associate professor of supply chain management in the C. T. Bauer College of Business and Hobby School of Public Affairs; and Susie Gronseth, professor of education. From the University of Texas is Junfeng Jiao, associate professor and director of the Urban Information Lab in the School of Architecture.

Alison Reese, executive director of digital fundraising nonprofit Souper Bowl of Caring, is also partnering with the team on the project.

Through the project, the UH-led team will use AI can to address issues relating to the "procurement, distribution, access, and utilization of food resources in underserved communities," according to the project's abstract.

In addition to meeting nutritional needs in the community, the team also is focused on finding better ways to address cultural preferences among food-insecure individuals. It will also look to streamline efforts and improve supply chain issues among food charities.

The program will also look to use food delivery services, like DoorDash, and award food donors with NFTs.

"The commitment of our team is to help our fellow neighbors," Ioannis Kakadiaris, principal investigator and Hugh Roy and Lillie Cranz Cullen Distinguished University Professor of Computer Science at UH's College of Natural Sciences and Mathematics, said in a statement. "This is evident in everything we do and permeates all our work."

Currently the team has been funded through Phase 1, which allows them to develop proofs of concept and early-stage prototyping, identify new partners and participate in curriculum from NSF.

Teams that have been awarded funds from the Convergence Accelerator will have an opportunity to submit proposals for up to $5 million in funding for Phase 2.

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Houston brain health co. secures $6.5M for rare disease study

neuro funding

Houston-based Goldenrod Therapeutics, part of Fannin Partners' portfolio, has announced the initial close of a $6.5 million series seed preferred stock round.

The round was led by Ataxia Ventures and an affiliate of Fannin, according to a news release.

Goldenrod Therapeutics plans to use the funding to support manufacturing, formulation optimization, IND-enabling studies and a Phase I study of its drug to treat brain inflammation, known as 11h.

The study will consider how 11h, which blocks the enzyme PDE4, could treat Friedreich’s ataxia (FA), a rare genetic disease that affects movement, speech and balance. To date, other PDE4 inhibitors have proven to regulate neuroinflammation and neuronal signaling, but have had adverse gastrointestinal side effects or have not reached enough of the central nervous system, according to Goldenrod.

The company says its 11h is expected to have "broad applicability" with limited emetric side effects.

“Our 11h program is a next-generation, orally bioavailable, brain-penetrant PDE4 inhibitor, where researchers overcame longstanding limitations associated with earlier PDE4 inhibitors," Dr. Dev Chatterjee, CEO of Goldenrod, said in the news release. "We believe this creates the potential for a best-in-class therapy for Friedreich’s Ataxia and a potential foundation for development across multiple neurodegenerative and neuroinflammatory disorders.”

11h was first developed at the University of Nebraska Medical Center (UNeMed). Houston-based Fannin Partners in-licensed the product 2020 and landed SBIR Phase I funding to support its initial development for opioid use disorder soon after.

Goldenrod has also received funding to study 11h's effectiveness for multiple sclerosis, methamphetamine addiction and cocaine addiction.

Goldenrod says it is developing 11h to target a variety of neurological and inflammatory conditions, including Alzheimer's disease, multiple sclerosis, ALS, substance use disorders, Batten disease, pain and traumatic brain injury.

27 Houston companies make Fortune 500 for 2026, led by energy giants

Houston HQs

Editor's note: This article has been updated to correct the number of companies based in the Dallas-Fort Worth area.

Houston is a giant among U.S. hubs for corporate headquarters.

The 2026 Fortune 500 lists 27 companies based in the Houston area, with many energy companies claiming top spots. Houston ties with Chicago for the second-most Fortune 500 headquarters, preceded only by New York City (53). Dallas-Fort Worth is home to 24 Fortune 500 headquarters.

Texas leads the nation for Fortune 500 headquarters (57), with California in the No. 2 spot and New York at No. 3.

“Texas is the undisputed headquarters of headquarters,” Gov. Greg Abbott said in a news release. “The world’s leading businesses invest with confidence in Texas because of our welcoming business climate, predictable regulatory environment, and skilled and growing workforce. People and businesses are choosing Texas because Texas works.”

The 2026 Fortune 500 ranks the largest U.S. corporations based on revenue in fiscal year 2025.

Here’s a rundown of the 27 Fortune 500 companies based in the Houston area.

  • No. 9 ExxonMobil
  • No. 21 Chevron
  • No. 29 Phillips 66
  • No.55 Sysco
  • No. 75 ConocoPhillips
  • No. 89 Enterprise Products Partners
  • No. 103 Plains GP Holdings
  • No. 133 Hewlett Packard Enterprise
  • No. 149 NRG Energy
  • No. 157 Quanta Services
  • No. 164 Baker Hughes
  • No. 173 Occidental Petroleum
  • No. 179 Waste Management
  • No. 201 EOG Resources
  • No. 204 Group 1 Automotive
  • No. 207 Halliburton
  • No. 223 Cheniere Energy
  • No. 236 Corebridge Financial
  • No. 262 Targa Resources
  • No. 266 Kinder Morgan
  • No. 388 Westlake
  • No. 435 CenterPoint Energy
  • No. 438 APA
  • No. 440 Comfort Systems USA
  • No. 455 NOV
  • No. 488 KBR
  • No. 496 Coterra Energy. Oklahoma City, Oklahoma-based Devon Energy and Houston-based Coterra Energy merged in early May, with the combined company retaining the Devon Energy name and the Houston headquarters.

The Greater Houston Partnership notes the Houston area soon will welcome its 28th Fortune 500 company. Expand Energy (formerly Chesapeake Energy), appearing at No. 362 on the 2026 list, says it’s moving its headquarters from Oklahoma City to Spring this year.

As the natural gas producer prepares to relocate to Texas, it’s hunting for a new leader. Nick Dell’Osso stepped down as president and CEO earlier this year. Board Chairman Michael Wichterich is interim president and CEO.

Dell’Osso became president and CEO of Oklahoma City-based Gulfport Energy effective May 28.

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This article first appeared on EnergyCapitalHTX.com.