3 Houston innovators to know this week

who's who

This week's roundup of Houston innovators includes John Higgins of illumiPure, Natara Branch of HX, and Daniel Murray of Covenant Underwriters. Photos courtesy

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — from insurtech to entrepreneurship — recently making headlines in Houston innovation.

John Higgins, CEO of illumiPure

CleanWhite can quickly and continuously sanitize high-touch areas through its light-based technology. Photo via LinkedIn

Houston-based illumiPure recently announced that it has received a worldwide patent for its LED white light disinfectant earlier this year, known as CleanWhite. The product can quickly and continuously sanitize high-touch areas while a room remains occupied and has shown an elimination of 99 percent of surface bacteria, spores, mold, biofilms, and viruses including SARS-CoV-2 through light-based technology. It's intended to be used in areas like kitchens, restrooms, and locker rooms and is safe for humans and pets.

CleanWhite uses spikes of light wavelengths at 405 and 470 nanometers to kill surface pathogens. Unlike other products on the market, CleanWhite can emit these levels without also emitting a visible purple-violet light while also suppressing blue light wavelengths.

"CleanWhite features technology that makes it the first of its kind, achieving a sought-after solution to produce 405+470 nm blue light as white light," John Higgins, CEO of illumiPure, says in a statement. "As a result of this revolutionary finding, we anticipate the patent’s success across a myriad of industries, including education, healthcare, hospitality, and retail.” Click here to read more.

Natara Branch, CEO of Houston Exponential

Meet Natara Branch — the new CEO of HX. Photo courtesy of Natara Branch

Ever since she accepted the new position as CEO of Houston Exponential, Natara Branch has been on a listening tour of Houston's innovation ecosystem. Branch explains on the Houston Innovators Podcast that she has a passion for the city of Houston, and she's got open ears to anyone in the ecosystem who wants to contribute to the advancement of the city's tech ecosystem.

As she explains, she is getting her fair share of feedback — but she has an ask for anyone who she's met.

"I am challenging people. You're not just going to give me feedback and sit back and watch. You're going to participate," Branch says. "I have not met one person who doesn't want Houston to win — they wouldn't be here if they didn't." Click here to read more and listen to the podcast.

Daniel Murray, co-founder and chief underwriter of Covenant Underwriters

The emerging insurtech industry has a plethora of opportunities for job seekers and more. Photo courtesy

More than 100,000 Houstonians work in insurance, according to Daniel Murray, co-founder and chief underwriter of Covenant Underwriters, a Houston-based insurtech start-up, building e-commerce insurance products for underserved niches. But the 400-year-old industry is hungry for tech talent.

In a guest column for InnovationMap, Murray explains the need for tech and innovation within insurance — and the opportunity the industry has.

"The adage goes that everyone in the insurance industry was either born into it or tricked into it," he writes. "This may have applied to the last generation, but today’s insurance industry offers vast opportunities (including remote) for every discipline, especially for tech job seekers." Click here to read more.

CleanWhite can quickly and continuously sanitize high-touch areas through its light-based technology. Photo via Getty Images

Houston tech company earns worldwide patent for LED disinfectant product

zip, zap

Houston-based illumiPure announced that it received a worldwide patent for its LED white light disinfectant earlier this year.

Known as CleanWhite, the product can quickly and continuously sanitize high-touch areas while a room remains occupied and has shown an elimination of 99 percent of surface bacteria, spores, mold, biofilms, and viruses including SARS-CoV-2 through light-based technology. It's intended to be used in areas like kitchens, restrooms, and locker rooms and is safe for humans and pets.

The product's ability to safely and continuously emit these levels of white light allows it to kill dangerous bacteria and pathogens in just a few hours.

"CleanWhite features technology that makes it the first of its kind, achieving a sought-after solution to produce 405+470 nm blue light as white light," John Higgins, CEO of illumiPure, said in a statement. "As a result of this revolutionary finding, we anticipate the patent’s success across a myriad of industries, including education, healthcare, hospitality, and retail.”

CleanWhite uses spikes of light wavelengths at 405 and 470 nanometers to kill surface pathogens. Photo via illumipure.com

The fixtures appear much like any other LED light and have been customized for the commercial, retail, healthcare, transportation, hospitality industries. illumiPure has already partnered with six Houston school districts, including Tomball ISD, Humble ISD, Galena Park ISD and Barbers Hill ISD.

“Nurses love illumiPure technologies because they feel protected,” Ricky Shelton, Energy Manager at Barbers Hill ISD, said in a statement.

According to the company, it is also in testing with a major sports franchise and is working with the Reem Mall in Abu Dhabi, which is slated to be the largest mall in the world once complete.

Founded in 2017, illumiPure focuses on air purification, surface disinfection and indoor/outdoor air quality monitoring.

In addition to CleanWhite, the company also has developed an air purifier product known as the Air Guardian, which has been shown to process air for longer dose times and uses intense ultraviolet light and plasma-like oxidizing energies to kill particles.

It also released The Portable by Air Guardian, a mobile version of the air purification system, and the Vertices AQS indoor/outdoor air quality sensor this year. A residential version of the Vertices sensor is slated to roll out later this year, as is one more new product, according to the company.

Earlier this year the company brought some of its production in-house, by the use of 25 3D printers for its Vertices units as well as other auxiliary components. The growing company plans to expand its headquarters in northwest Houston sometime next year.

John Higgins is the CEO of illumiPure. Photo via LinkedIn

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Houston researcher secures $1.7M to develop drug for aggressive form of breast cancer

cancer research

A University of Houston researcher has joined a $3.2 million effort to develop a new drug designed to attack a cancer-driving protein commonly found in triple-negative breast cancer.

Triple-negative breast cancer (TNBC) is one of the most difficult-to-treat forms of cancer and accounts for 10 percent to 15 percent of all breast cancer cases. The disease gets its name because tumors associated with it test negative for estrogen receptors, progesterone receptors and excess HER2 protein, making it difficult to target. Due to this, TNBC is often treated with general chemotherapy, which can come with negative side effects and drug resistance, according to UH.

UH College of Pharmacy research associate professor Wei Wang is developing a drug that can target the disease more specifically. The drug will target MDM2, a protein often overproduced in TNBC that also contributes to faster tumor growth.

Wang is working on a team led by Wei Li, director of the University of Tennessee Health Science Center College of Pharmacy’s Drug Discovery Center. She has received $1.7 million to support the research.

Wang and UH professor of pharmacology and toxicology Ruiwen Zhang have discovered a compound that can break down MDM2. In early laboratory models, the compound has shown the ability to shrink tumors.

Wang and Zhang will focus on understanding how the treatment works and monitoring its effectiveness in models that closely mirror human disease.

“We will study how the drug targets MDM2 and evaluate the most promising drug candidates to determine effective dosing, understand how the drug behaves in the body, compare it with existing treatments and assess early safety,” Wang said in a news release.

Li’s team at the University of Tennessee will be working on the chemistry and drug design end of the project.

“This work could lead to an entirely new class of therapies for triple-negative breast cancer,” Li added in the release. “We’re hopeful that by directly removing the MDM2 protein from cancer cells, we can help more patients respond to treatment regardless of their tumor type.”

10+ Houston innovation leaders in the spotlight at SXSW 2026

where to be

Houston's innovation scene will be well represented at South by Southwest (SXSW) this month.

The week-long, Austin-based conference and festival will spotlight some of the Bayou City's leaders in health care, energy, space and more. The event kicks off today, March 12, and runs through March 18. The SXSW Innovation Conference will feature keynotes, workshops, mentoring sessions and more throughout various venues in the city.

Here's who to see and when and where to find them:

March 12

Aileen Allen, venture partner at Mercury Fund

Mentor Session from 4-5:15 p.m. at Hilton Austin Downtown

Allen will host a mentoring session focused on funding, marketing, advertising, PR and the future of work.

March 13

Heath Butler, partner at Mercury Fund

SXSW Pitch-Smart Cities, Transportation, Manufacturing & Logistics from 2:30-3:30 p.m. at the J.W. Marriott

Butler will judge five innovative startups as they pitch their solutions to advance smart cities, enhance transportation systems, modernize manufacturing, transform logistics, and strengthen government infrastructure and civic operations.

Jonathan Cirtain, CEO and president of Axiom Space

The Clock is Ticking for Space - Replacing the ISS from 4-5 p.m. at the J.W. Marriott

Cirtain will discuss Axiom's pursuit of building the world’s first commercial space station.

March 14

Jesse Martinez, founder and CEO of LSA Global

SXSW Pitch-Intelligent Systems, Robotics, & Multisensory Technology from 10-11 a.m. at the J.W. Marriott

Martinez will judge five innovative startups as they pitch their technologies that aim to enhance the way people connect, communicate and share unique life experiences with those around them in a digital ecosystem.

Jennifer Schmitt, head of operations at Rhythm Energy

Powering Texas with Reliable Integrated High-Demand Energy from 10-11 a.m. at Marlow

Schmitt will join a panel to discuss how EirGrid, the state-owned electric power transmission operator in Ireland, is pioneering solutions as the country works toward 80 percent renewable integration by 2030.

Saki Sasagawa, director of business development for JETRO Houston

Now is Japan's Time: Leading the Future with Deep Tech from 10-11 a.m. at the J.W. Marriott

Sasagawa joins a panel that will share real-time insights from diverse perspectives on the forefront of Japan’s deep tech and IP businesses.

March 15

Bosco Lai, CEO and co-founder of Little Place Labs

SXSW Pitch Alumni: Where Are They Now? from 10-11 a.m. at the J.W. Marriott

Lai joins a panel of four former SXSW Pitch winners to share how they leveraged the platform to take their startups to the next level.

Tara Karimi, cofounder and chief science and sustainability officer at Cemvita

South by South America: The Rise of Southern Brazil Tech from 2:30-3:30. p.m. at The Line

Karimi will participate in a panel to discuss how Rio Grande do Sul, Brazil's southernmost state, is attracting elite talent and AI infrastructure and share insights on navigating the next wave of South American tech growth.

March 16

Dr. Pavitra P. Krishnamani, emergency medicine physician at The University of Texas MD Anderson Cancer Center

Viva La Revolution: How the Digital Age is Transforming Wellness from 11:30 a.m.-12:30 p.m. at Hilton Austin Downtown

Krishnamani will discuss the latest advancements and policies that can accelerate the digital age of health care, such as wearables, telehealth and artificial intelligence.

March 18

Charlie Childs, co-founder and CEO of Intero Biosystems

Spinning Out: What It Takes to Build a University Startup from 2:30-3:30 p.m. at The Line

Childs will join founders who spun their companies out of the University of Michigan to share the real story of navigating IP, early capital, team building, market validation and the “valley of death.”

Dr. James Allison, regental chair of immunology and director of The Allison Institute at The University of Texas MD Anderson Cancer Center

Dr. Padmanee Sharma, professor in the Department of Genitourinary Medical Oncology, Division of Cancer Medicine at The University of Texas MD Anderson Cancer Center

Beyond Checkpoints: Immunotherapy’s Next Act from 2:30-3:30 p.m. at the J.W. Marriott

Allison and Sharma will sit down with 21-year-old, Stage 4 cancer survivor Sharon Belvin and Time Magazine journalist Alice Park will discuss the future of immunotherapy and what challenges remain.

Last year, Houston startups Little Places Labs and Helix Earth won top prizes in their respective categories at the prestigious SXSW Pitch event, held this year from March 13-14. No Houston startups were named finalists to compete in this year's event.

NASA revamps Artemis moon landing program by modeling it after Apollo

To the moon

NASA is revamping its Artemis moon exploration program to make it more like the fast-paced Apollo program half a century ago, adding an extra practice flight before attempting a high-risk lunar landing with a crew in two years.

The overhaul in the flight lineup came just days after NASA’s new moon rocket returned to its hangar for more repairs, and a safety panel warned the space agency to scale back its overly ambitious goals for humanity’s first lunar landing since 1972.

Artemis II, a lunar fly-around by four astronauts, is off until at least April because of rocket problems.

The follow-up mission, Artemis III, had been targeting a landing near the moon’s south pole by another pair of astronauts in about three years. But with long gaps between flights and concern growing over the readiness of a lunar lander and moonwalking suits, NASA’s new administrator Jared Isaacman announced that mission would instead focus on launching a lunar lander into orbit around Earth in 2027 for docking practice by astronauts flying in an Orion capsule.

The new plan calls for a moon landing — potentially even two moon landings — by astronauts in 2028.

“Everybody agrees. This is the only way forward,” Isaacman said.

The hydrogen fuel leaks and helium flow problems that struck the Space Launch System rocket on the pad at NASA's Kennedy Space Center in February also plagued the first Artemis test flight without a crew in 2022.

Another three-year gap was looming between Artemis II and the moon landing by astronauts as originally envisioned, Isaacman said.

Isaacman stressed that “it should be incredibly obvious” that three years between flights is unacceptable. He'd like to get it down to one year or even less.

Isaacman, a tech billionaire who bought his own trips to orbit and performed the world’s first private spacewalk, took the helm at NASA in December.

During NASA’s storied Apollo program, he said, astronauts’ first flight to the moon was followed by two more missions before Neil Armstrong and Buzz Aldrin landed on the moon. What's more, he added, the Apollo moonshots followed one another in quick succession, just as the earlier Projects Mercury and Gemini had rapid flight rates, sometimes coming just a few months apart.

Twenty-four Apollo astronauts flew to the moon from 1968 through 1972, with 12 of them landing.

“No one at NASA forgot their history books. They knew how to do this," Isaacman said. “Now we're putting it in action.”

To pick up the pace and reduce risk, NASA will standardize its Space Launch System rockets moving forward, Isaacman said. These are the massive rockets that will launch astronauts to the moon aboard Orion capsules. At the same time, Elon Musk's SpaceX and Jeff Bezos' Blue Origin are speeding up their work on the landers needed to get the astronauts from lunar orbit down to the surface.

Isaacman said next year will see an Orion crew rendezvousing in orbit around Earth with SpaceX's Starship, Blue Origin's Blue Moon or both landers. It's similar to the methodical approach that worked so well during Apollo in the late 1960s, he noted. Apollo 8, astronauts' first flight to the moon, was followed by two more missions before Armstrong and Aldrin aimed for the lunar surface.

“We should be getting back to basics and doing what we know works,” he said.

The Aerospace Safety Advisory Panel recommended that NASA revise its objectives for Artemis III “given the demanding mission goals.” It’s urgent the space agency do that, the panel said, if the United States hopes to safely return astronauts to the moon. Isaacman said the revised Artemis flight plan addresses the panel's concerns and is supported by industry and the Trump administration.

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