Entrepreneurs' Organization had seven of its members give TED-style talks on April 25. Ammar Selo

Moving the needle on something — whether it's changing the world or growing your business — hearing how others accomplished their own goals can be a beacon of hope and guidance for others.

The local Entrepreneurs' Organization chapter, EO Houston, hosted a series of seven TED Talk-style talks by members of the organization. These seven entrepreneurs discussed everything from being an introvert in a world of extroverts to the biggest security threat to American citizens: obesity. EO Talks took place at a breakfast event on April 25 at Houston Baptist University. If you missed the event, check out these overheard quotes from the day of discussions.

“When you get people involved in your organization, your job (as CEO) is alignment. Keep your team aligned with the strategic objectives of your company.”

— Paul Sarvadi, chairman, CEO and co-founder of Insperity, in his talk, "Take Care of Your People: An Entrepreneur's Journey." Connectivity is key, says Sarvadi.

“Taking care of your people is not rocket science. In fact, rocket science would be easier. It involves math and science — it works the same every day. But as soon as you put people in the mix, what worked yesterday might not work today.”

— Sarvadi continued in his talk about the importance of human resources in the the work place.

“What if everyone in the world knew what they stood for — imagine what that world would look like. We would know how we fit. We would be the best versions of ourselves. And, the world would be the best version of itself.”

— Winnie Hart, founder of TwinEngine in her talk, "What Do You Stand For?" Hart discussed finding one's identity and motivators — both in business and in life.

“Everywhere we look introverts are living in an extroverted world. It’s natural if you’re an introvert, like me, to feel a little insecure or that you feel the need to compete with your extraverted friends.”

— Darlene Gagnon, CEO and co-founder of Kinnect Global Management Services in her talk, "The Introverted Entrepreneur Competing in an Extroverted World." Gagnon says that introverts on track to be the most successful entrepreneurs with their execution skills, detail oriented nature, and ability to tune out the noise.

“It is the men in our lives that need to take action. Gentlemen, stand with us. Help us create a better presence so that we can sustain a future.”

— Shoshi Kaganovsky, CEO and founder of SensoLeak Global, in her talk, "Women Entrepreneurs—To Be..Or..To Be The Best." Kaganovsky compared how people say, "behind every great man is a woman," to how female leaders also need the support from the other gender.

“Entrepreneurship is an endless circle of reinventing yourself, being able to change, and keeping a positive attitude while doing so.”

— Kaganovsky continued in her talk as advice to the room of entrepreneurs.

“We can escape this crushing threat we call obesity. How are you going to make your escape?”

— Dr. Joe Galati, liver disease expert, radio host and author in his talk, "America's #1 National Security Threat." Galati argued that it's not Russia or North Korea that pose a major threat to the United States — it's our own health issues caused by obesity.

“We’ve all heard of the term ‘side hustle.' Maybe my dad invented the ‘side hustle.’”

— Chris Hotze, CEO and founder of Crescere Capital, in his talk, "Understanding the Power of Recurring Revenue." Hotze tells the story of how his father created a residential real estate side business out of necessity, and how that entrepreneurialism affected his own business career.

“As entrepreneurs, as long as we see control, we visualize an opportunity far greater than we see the risk.”

— Ali Nasser, CEO of AltruVista in his talk, "The Entrepreneur's Opportunity Cost," Nasser explains how entrepreneurs are hesitant to put money in the stock market, yet dive into ownership and risks for their own businesses.

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New UH survey reveals concerns over AI data center growth in Houston

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A new report out of the University of Houston shows that area residents remain wary of the long-term effects of operating data centers.

The recent survey from the University of Houston’s latest SPACE City Panel, conducted by the Center for Public Policy at the Hobby School of Public Affairs, shows that while 85 percent of Houston-area residents use AI, nearly 63 percent oppose the construction of AI data centers within 1 mile of their homes.

Respondents’ concerns centered around data centers’ high energy demand and the area’s power grid reliability. According to the survey, 32 percent of residents who oppose local data center projects would be more likely to support the centers if they relied on renewable energy over fossil fuels.

“Respondents understand that AI can bring economic and educational benefits, but they are also concerned about the physical infrastructure needed to fuel AI, especially data centers,” Soran Mohtadi, post-doctoral fellow at the Hobby School and a researcher on the report, said in a news release. “This physical infrastructure demands more electricity and water, leading to environmental impacts.”

Experts estimate that 6.5 gigawatts of data center capacity will be added to the Texas grid by 2030. And Houston’s data center capacity is predicted to more than double by 2028.

The Electric Reliability Council of Texas also projects electricity demand could reach 218 gigawatts by 2031, which would be more than double the record peak set in August 2023. Data centers are expected to account for 86 gigawatts of that new demand.

Survey respondents also said they are concerned about the state's future water supply, given the large amounts of water that data centers need to stay cool.

In terms of who’s responsible for that issue, 57.6 percent of respondents said they put the onus on Texas lawmakers, while 31.5 percent say tech companies should be responsible.

Additionally, more than 75 percent of respondents believed that data center developers and technology companies—not residents—should bear the cost of infrastructure upgrades to support data centers.

“Every decision legislators make has implications on residents’ everyday lives and local infrastructure now and in the future,” Maria P. Perez Arguelles, lead researcher on the report and research assistant professor at the Hobby School, added in the news release. “This issue is going to become more important in years to come, so this is just the beginning.”

Read the full report here.

Houston-born Cemvita makes breakthrough in sustainable fuel production

clean fuels

Houston-based biotech company Cemvita announced that it recently reached a critical milestone in the development of its FermOil product, which can be used to create Sustainable Aviation Fuel (SAF) and other renewable fuels at industrial scale.

The company shared in a news release that it completed a 75,000-liter industrial fermentation run at Belgium's Bio Base Europe Pilot Plant.

The campaign achieved target technical metrics for the production of FermOil, Cemvita’s renewable natural oil (RNO). FermOil is produced from industrial crude glycerin, an industrial byproduct, as opposed to traditional sugar-based feedstocks used in many bio-oil fermentation processes. It's designed to be a drop-in feedstock for creating SAFs.

Cemvita had previously advanced its FermOil production process through multiple scale-up stages before successfully reaching the 75,000-liter demonstration campaign, according to the company.

“This is not just a fermentation milestone,” Moji Karimi, CEO at Cemvita, said in the release. “It is a blueprint for how existing industrial infrastructure can evolve into circular bioeconomy infrastructure. Every biodiesel plant generating crude glycerin is a potential platform for renewable natural oil production.”

The milestone also supports the deployment of Cemvita’s industrial biomanufacturing platform, FermWorks, which integrates with existing energy and industrial infrastructure to turn waste carbon streams into SAFs and other materials. According to the release, Cemvita plans to move forward with commercial deployment discussions with partners in Brazil, Europe and in the UK. Cemvita already has a partnership with the Brazilian sustainable research institution REMA.

“We are proud to support innovative companies like Cemvita in scaling breakthrough industrial biotechnology solutions,” Hendrik Waegeman, head of business operations at Bio Base Europe Pilot Plant, added in the release. “Successfully operating at the 75,000-liter scale using a feedstock such as crude glycerin highlights both the maturity of the technology and the quality of the scale-up execution achieved by the Cemvita team.”

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This article originally appeared on our sister site, EnergyCapitalHTX.com.

Eli Lilly scoops up Houston biotech startup in $300 million deal

big pharma deal

Pharmaceutical giant Eli Lilly has acquired Houston biotech startup CrossBridge Bio, which develops antibody-drug conjugates for cancer, in a deal worth up to $300 million. The deal was celebrated by TMC Venture Fund and the University of Texas Health Science Center at Houston last week.

CrossBridge, founded in 2023, is developing ADCs based on research by Kyoji Tsuchikama and Zhiqiang An, both of UT Health Houston. Tsuchikama is an associate professor of medicinal chemistry and a globally recognized ADC pioneer, and An is a professor of molecular science and vice president of drug discovery.

Antibody-drug conjugates (ADCs) are a potent combination of targeted therapy and chemotherapy that kills cancer cells while saving healthy tissue.

Clinical trials for CrossBridge’s primary ADC candidate, CBB-120, are expected to start this year, pending approval from the U.S. Food and Drug Administration (FDA).

“I’m proud of how well our team has executed and advanced our platform in such a short time since the company’s founding,” Michael Torres, co-founder and CEO of CrossBridge, said in a news release. “By becoming a part of Lilly, a leader in patient-focused therapeutic development, we are well-positioned to further accelerate the clinical potential of this approach.”

Under the Lilly deal, CrossBridge shareholders were expected to receive an upfront payment along with a follow-up payment based on the achievement of certain milestones.

In 2024, CrossBridge closed a $10 million seed round. Among the investors in CrossBridge are the Texas Medical Center Venture Fund, CE-Ventures, Alexandria Venture Investments, Portal Innovations, Linden Lake Labs, and the Cancer Prevention and Research Institute of Texas (CPRIT). It was formed in TMC Innovation’s Accelerator for Cancer Therapeutics program."Built within the TMC ecosystem, CrossBridge Bio grew with the support, funding, and resources that helped shape its trajectory. TMC led the company's early financing and watched it evolve from its earliest days to its acquisition by Eli Lilly," William McKeon, president and CEO of the Texas Medical Center, shared in a LinkedIn post. "[This is a] strong reminder that breakthrough science and the right early backing can change what’s possible."