Digital Fight Club is making its triumphant Houston return next week. Have you gotten your virtual tickets? Photo by Emily Jaschke/InnovationMap

In 2019, Houston innovators went head to head for the first Houston Digital Fight Club. While COVID-19 postponed a repeat match-up, the organizers have teamed up to put on a virtual event like none other.

Dallas-based Digital Fight Club, which first premiered in 2016, was founded by Michael Pratt who wanted the event structure to be intentionally different from your run-of-the-mill tech networking events. In Digital Fight Club, two innovation specialists "fight" against one another, with a referee steering the conversation, and the audience is involved and votes in real time for the winner.

The event came to Houston two years ago, presented by Accenture, and the two organizations wanted to be able to replicate the high-energy event online for 2021. (Note: InnovationMap is on the steering committee for the event.)

"We as Accenture are stoked to bring back Digital Fight club to our amazing city where provocative Houston topics will be debated by some of H-Town's most brilliant minds," says Accenture Houston Innovation Hub's Jessica Guerrero, who serves as the associate hub director.

The previous Houston event covered innovative topics, such as artificial intelligence, the future of primary care, and technology's hold on humans. Check out overheard moments and photos from the last event.

"Houston's well deserved reputation as an innovation city is the perfect ingredient for Digital Fight Club," Pratt tells InnovationMap. "What better forum to see the best minds debate the most pressing issues in business and technology."

Through the work of the two teams, Digital Fight Club will return to Houston on Tuesday, October 26, at 7 pm, virtually. Tickets are $20 per person and can be purchased online. This year's topics and fighters includes:

  • Energy Transition: What technology is king to get us there? Fighters: Moji Karimi, CEO of Cemvita Factory, vs Trevor Best, CEO of Syzygy Plasmonics
  • Space Race: Who will lead space commercialization? Fighters: Trent Martin, vice president of aerospace at Intuitive Machines, vs Steve Gonzalez, partner at Seldor Capital (retired NASA)
  • Digital Divide: The greatest barrier to bridging the divide? Fighters: Ashley DeWalt, managing director of DivInc, vs Jesse Martinez, co-founder of LatinX Startup Alliance
  • Sweet Teams are Made of This: The post-pandemic employee experience. Fighters: Brad Deutser, CEO of Deutser, vs Joe Alapat, CEO of Liongard
  • Innovation in a Virtual World: Impossible? Fighters: Lawson Gow, founder of The Cannon, vs Robert Pieroni, director of economic development at Central Houston Inc.

Each fighter will open with 45 seconds each, followed by two 30 seconds rebuttals each. Referees will have a chance to ask a follow up, then each fighter will respond for 15 seconds. Referees include:

  • Mary Beth Gracy, managing director of Accenture's Houston office
  • Scott Gale, executive director of Halliburton Labs
  • Sam Gunderson, director of partnership development at NASA
  • Elizabeth Haines McGee, director of innovation and engagement at Intel
  • Steve Rader, deputy director of collaborative innovation at NASA

Clearly, you shouldn't expect your average business event call. The platform that's hosting the event allows for attendees to join "rooms" with friends, coworkers, and more. Within the rooms, you can chat about the fighter's argument and even respond with emojis. You can even throw a tomato at a fighter you disagree with.

"As an attendee get ready to move beyond the traditional Zoom call and be immersed in an interactive environment where you can cheer on your favorite fights or even show your disagreement with digital tomatoes, all from your own virtual pink couch," Guerrero says. "So grab your favorite humans, come attend this entertaining experience and witness the throw down."

The virtual edition of Digital Fight Club first took place in Dallas. Now the interactive event is coming to Houston. Photo courtesy of Accenture

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Texas universities develop innovative open-source platform for cell analysis

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What do labs do when faced with large amounts of imaging data? Powerful cloud computing systems have long been the answer to that question, but a new riposte comes from SPACe.

That’s the name of a new open-source image analysis platform designed by researchers at Baylor College of Medicine, Texas A&M University and the University of Houston.

SPACe, or Swift Phenotypic Analysis of Cells, was created to be used on standard computers that even small labs can access, meaning cellular analysis using images produced through cell painting has a lower barrier to entry than ever before.

“The pharmaceutical industry has been accustomed to simplifying complex data into single metrics. This platform allows us to shift away from that approach and instead capture the full diversity of cellular responses, providing richer, more informative data that can reveal new avenues for drug development,” Michael Mancini, professor of molecular and cellular biology and director of the Gulf Coast Consortium Center for Advanced Microscopy and Image Informatics co-located at Baylor College of Medicine and TAMU Institute for Bioscience and Technology.

SPACe is not only accessible because of its less substantial computational needs. Because the platform is open-source, it’s available to anyone who needs it. And it can be used by academic and pharmaceutical researchers alike.

“The platform allows for the identification of non-toxic effects of drugs, such as alterations in cell shape or effects on specific organelles, which are often overlooked by traditional assays that focus largely on cell viability,” says Fabio Stossi, currently a senior scientist with St. Jude Children’s Research Hospital, the lead author who was at Baylor during the development of SPACe.

The platform is a better means than ever of analyzing thousands of individual cells through automated imaging platforms, thereby better capturing the variability of biological processes. Through that, SPACe allows scientists an enhanced understanding of the interactions between drugs and cells, and does it on standard computers, translating to scientists performing large-scale drug screenings with greater ease.

"This tool could be a game-changer in how we understand cellular biology and discover new drugs. By capturing the full complexity of cellular responses, we are opening new doors for drug discovery that go beyond toxicity,” says Stossi.

And the fact that it’s open-source allows scientists to access SPACe for free right now. Researchers interested in using the platform can access it through Github at github.com/dlabate/SPACe. This early version could already make waves in research, but the team also plans to continually improve their product with the help of collaborations with other institutions.

The Ion names new coworking partner for Houston innovation hub

Where to Work

Rice University subsidiary Rice Real Estate Co. has tapped coworking company Industrious as the new operator of the Ion’s 86,000-square-foot coworking space in Midtown. Industrious replaces WeWork-owned Common Desk in that role.

The Ion, owned by Rice Real Estate and located at 4201 Main St., is a 266,000-square-foot office building and innovation hub in the 16-acre Ion District.

Features of the coworking space include private suites and offices, dedicated desks, phone booths and conference rooms. In 2022, Common Desk said it was expanding the space by 28,000 square feet, bringing it to the current size.

“(Industrious’) unparalleled expertise in delivering quality, hospitality-driven workspaces complements our vision of creating a world-class ecosystem where entrepreneurs, corporations, and academia converge to drive innovation forward,” Ken Jett, president of Rice Real Estate, said in a statement.

Natalie Levine, senior manager of real estate at Industrious, says her company will work with Rice Real Estate “to continue to position the Ion as an invaluable contributor to the growth of Houston’s innovation community.”

Dallas-based commercial real estate services company CBRE said Jan. 14 that it had agreed to acquire Industrious in a deal valued at $400 million.

The Ion is Industrious’ second location in Houston. The company’s other local coworking space is at 1301 McKinney St.

Office tenants at the Ion include Occidental Petroleum, Fathom Fund, Activate, Carbon Clean, Microsoft and Chevron Technology Ventures.

Texas ranks among the 5 best states to start a business in 2025

Best for Biz

As one of the largest states in the U.S., it's no surprise Texas is big on business and entrepreneurship. Now the state is earning new praise among WalletHub's 2025 list of "Best & Worst States to Start a Business."

The Lone Star State claimed the No. 4 spot in the report's rankings, proving that Texas is in a much better business shape than it was last year when it earned No. 8 in WalletHub's annual report.

The study compared all 50 states across 25 metrics to determine the best places to start, grow, and find success with a new business. Factors that were considered include the number of startups per capita, job growth rates, financing accessibility measures, labor costs and corporate tax rates.

The three states to outperform Texas in the 2025 report are Florida (No. 1), Georgia (No. 2), and Utah (No. 3). Idaho rounded out the top five.

Across the study's three main categories, Texas performed the best in the "business environment" category, earning No. 1 nationally. This section compares the states based on five-year business survival rates, average business revenues growth and more.

Texas ranked No. 12 in the nationwide comparison of "access to resources" – which covers working age population growth, venture investment amounts per capita and other means – and earned a fair No. 34 in the report's "business costs" ranking.

But Texas can still do better with its business friendliness to reclaim a top-three overall ranking, which the state last earned in 2023.

WalletHub analyst Chip Lupo said in the report that it is imperative for potential new business owners to establish their enterprise in a place that can maximize their ability to succeed.

"Around half of all new businesses don’t survive five years, so the idea of becoming a business owner can be daunting, especially with the current high cost of living," Lupo said. "The best states have low corporate tax rates, strong economies, an abundance of reliable workers, easy access to financing and affordable real estate. On top of that, you’ll need to make sure you start in a place with an engaged customer base, if you’re operating locally."

Houston has also proven to be at the top of the destination list for entrepreneurs who are looking for their next venture.

The top 10 best states to start a new business in 2025 are:

  • No. 1 – Florida
  • No. 2 – Georgia
  • No. 3 – Utah
  • No. 4 – Texas
  • No. 5 – Idaho
  • No. 6 – Oklahoma
  • No. 7 – Nevada
  • No. 8 – Colorado
  • No. 9 – Arizona
  • No. 10 – Kentucky
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This story originally appeared on our sister site, CultureMap.