Houston-based oil field service company, Halliburton, has introduced its new startup incubator. Getty Images

Not intending to be left out of the energy transition, a Houston-based, multinational oil and gas services company has announced its new incubator for startups to advance cleaner, affordable energy.

Halliburton Company has introduced Halliburton Labs this week and named Houston-based Nanotech Inc., which uses nanotechnology for thermal insulation and fireproofing, as its first participant. Nanotech — along with future entrepreneurs and academics — will have access to the Halliburton facilities, the company's experts, and its network.

"Halliburton Labs reflects our commitment to the science and continued evolution of sustainable, reliable energy," says Jeff Miller, chairman, president, and CEO at Halliburton, in a news release. "We firmly believe that oil and gas will remain an affordable and reliable energy resource for decades to come. At the same time, we recognize the importance of developing alternative energy sources. We are excited to help advance solutions that have the potential for a long term, meaningful impact and that align well with our sustainability objectives."

The program will be based out of Halliburton's North Houston headquarters and will be led by executive director, Scott Gale. The primary focus of the incubator is to help advance and scale the participating startups, which includes developing and advancing products, securing financing and customers, and more.

Startups that will be considered for the program must be past the proof-of-concept phase, and a formal application process will roll out in September. According to the release, additional startup participants will be announced in the next few months. Meanwhile, Nanotech has already moved into the new lab at Halliburton.

"We also couldn't be more pleased to have Nanotech, Inc. as the first participant of Halliburton Labs," says Miller in the release. "Nanotech delivers technology that will change the way we think about energy conservation and fire safety across many sectors."

Nanotech's Nano Shield products can protect from fire damage as well as improve energy efficiency. Mike Francis, CEO and co-founder, launched Nanotech in 2019.

"We are incredibly excited to have been selected as an anchor for Halliburton Labs and help drive meaningful change and innovation in the energy sector," says Francis, in the release. "Access to Halliburton Labs' resources and world-class facilities will help accelerate our growth and deliver our transformative line of products. Through this collaboration, we intend to fundamentally shift the fireproofing and thermal insulation markets towards more effective and environmentally friendly solutions."

The Cannon hosted a B2B pitch night, and all three companies have a mission to change the world. Courtesy of The Cannon

3 Houston entrepreneurs changing the world with their B2B startups

On purpose

I think it's safe to say that most B2B startups don't have sustainability or a mission-driven purpose at the core of their business model. In fact, it's probably safe to say that about any for-profit company of any size.

Three Houston entrepreneurs pitched their companies at The Cannon's recent B2B pitch night, and they all have something in common: They're not normal B2B startups. Each company has a mission to change the way we're doing something — from hiring to construction — in a way that's better for the world.

Natalie Goodman, founder and CEO IncentiFind

Courtesy of IncentiFind

Natalie Goodman realized there was a disconnect between builders and green incentives the government provides.

"The government is strapped — they have all this money that they want to give away, but not the (marketing) money to get the word out," Goodman told InnovationMap last month. "That's where IncentiFind stepped in."

IncentiFind is a portal for green incentives and works in three steps. First, you do a search for green incentives in your area — this part is completely free to the commercial developer or home owner. Next, the user might opt to pay IncentiFind to find the exact incentives for the project and submits the applications for the project. The final step is a promise of a 10 times return on investment.

A million green projects are completed in the United States each year, and IncentiFind is getting in front of that by forming partnerships with lenders, commercial developers, architects, etc., Goodman says to the crowd. Read more about IncentiFind here.

Jeff Miller, CEO of Potentia

Courtesy of The Cannon

The facts and figures are pretty startling. One-in-40 school-age children are on the autism spectrum and one-in-five college-educated autistic individuals don't have a job when they graduate, Jeff Miller says during his pitch at The Cannon. Miller, who has a long career in staffing around the world, founded his company Potentia to help correct this growing employment problem.

"We're seeking to help employers build their 21st century workforce at the intersection of technology, leadership, and, most specifically, the autism spectrum," he says.

Potentia is a technology-focused recruitment firm with resources and opportunities for applicants on the Autism spectrum. For Miller, it's personal. His 16-year-old son has autism, and Miller wants a world where his son can have access to employment opportunities around the world.

"I think we're in a position to improve this model here in Houston, and take it to other cities," Miller says. "The reality is this is a challenge that exists in every major city."

Kim Raath, co-founder of Topl

Courtesy of Topl

Sure, blockchain is a major buzzword nowadays, but for Topl co-founder Kim Raath it means having the ability to track the sustainability of a purchase. Topl's technology is able to tell you if your diamond ring came from a war-torn country or if your coffee's farmer was paid fairly.

Raath says she's seen an increased need for sustainable and transparent businesses that can prove their impact, but it's expensive to do that.

"These businesses are spending so much money on trying to prove this impact," Raath says in her pitch at The Cannon. "We have customers spending close to 15 percent in operational expenses just to be able to trace their growth."

The company, founded by three Rice University students, is growing. In May, Raath says they have four new ventures being developed, and by 2020, they want to have 24 live ventures with a monthly revenue of over $30,000.

"At Topl, we are really going to change the world," Raath tells the crowd. "But I can prove it to you." Read more about Topl here.

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Houston digital health platform Koda lands strategic investment

money moves

Houston-based advance care planning platform Koda Health has added another investor to the lineup.

The company secured a strategic investment for an undisclosed amount from UPMC Enterprises, the commercialization arm of the University of Pittsburgh Medical Center. The funding is part of Koda's oversubscribed series A funding round that closed in October, according to a release.

"UPMC Enterprises’ investment is a meaningful signal, not just to Koda, but to the broader market," Dr. Desh Mohan, chief medical officer and co-founder of Koda Health, said in the news release. "It validates that health systems are ready to invest in infrastructure that makes advance care planning work the way it should: proactively, at scale, and with the human support that these conversations require. Having UPMC Enterprises as a strategic investor puts us in a unique position to prove what's possible."

Koda has raised $14 million to date, according to a representative from the company. Its series A round was led by Evidenced, with participation from Mudita Venture Partners, Techstars and the Texas Medical Center last year. At the time, the company said the funding would allow it to scale operations and expand engineering, clinical strategy and customer success. The company described the round as a "pivotal moment," as it had secured investments from influential leaders in the healthcare and venture capital space.

Koda Health, which was born out of the TMC's Biodesign Fellowship in 2020, saw major growth last year, as well, and now supports more than 1 million patients nationwide through partnerships with Cigna Healthcare, Privia Health, Guidehealth, Sentara, UPMC and Memorial Hermann Health System.

The company integrated its end-of-life care planning platform with Dallas-based Guidehealth in April 2025 and with Epic Systems in July 2025. It also won the 2025 Houston Innovation Award in the Health Tech Business category. Read more here.

New 'living pharmacy' biotech company launches out of Rice venture studio

fighting cancer

Rice University’s biotech venture studio RBL LLC has launched a new “living pharmacy” company, Duracyte, designed to make cancer treatment easier on patients.

Backed by an up to $45 million Advanced Research Projects Agency for Health (ARPA-H) award, Duracyte aims to commercialize implantable biohybrid pharmacy devices that are designed to produce therapeutic proteins inside the human body around the clock, replacing the need for regular injections and infusions for some cancer patients.

The company’s main platform is its Hybrid Advanced Molecular Manufacturing Regulator (HAMMR), a rechargeable, implantable device that can sense biological signals, monitor tumor environments and adjust therapeutic output in real time. HAMMR has wireless communication capabilities, which allow patients and clinicians to remotely monitor results through an app every five minutes and make changes to treatment plans without a hosptial visit. Additionally, the device can generate its own oxygen supply, which is key for the therapeutic cells’ survival.

“Biologic medicines such as monoclonal antibodies, cytokines and metabolic regulators already account for a significant share of modern therapeutics, but the way we deliver them today often requires frequent injections or infusions that can be demanding for patients and lead to inconsistent drug levels,” Daniel Anderson, MIT professor and co-founder of Duracyte, said in a news release. “Our vision is to enable a continuous, stable therapy by producing these medicines directly inside the body, which could improve treatment consistency, reduce side effects and ultimately transform how biologic therapies are delivered across many diseases.”

Duracyte’s first clinical trial is slated to begin by the end of 2026 and will focus on recurrent ovarian cancer. The Phase I study will build upon existing work on encapsulated cytokine pharmacy technology, and the company hopes that within a few years this treatment can reach clinical application.

The development of Duracyte is supported by ARPA-H's Targeted Hybrid Oncotherapeutic Regulation (THOR) project, which supports a multidisciplinary research consortium co-led by Omid Veiseh, a professor of bioengineering at Rice. The consortium also includes others at Rice, The University of Texas MD Anderson Cancer Center, Stanford University, Carnegie Mellon University, Northwestern University and the University of Houston, plus industry collaborators like Chicago-based CellTrans.

“What we are building is the culmination of years of progress in cell engineering, biomaterials and implantable device technology,” Veiseh added in the release. “By combining these advances with real-time sensing and adaptive drug delivery, we are working with the support of RBL to create a true ‘living pharmacy’ that can deliver continuous, precisely controlled biologic therapies and fundamentally change how these treatments reach patients.”

RBL launched in 2024 and is based out of Houston’s Texas Medical Center Helix Park. Duracyte is the third company launched by RBL, including Sentinel BioTherapeutics, a clinical-stage immunotherapy company developing localized cytokine therapies for solid tumors, and SteerBio, a regenerative medicine company targeting lymphedema.

“Duracyte exemplifies the kind of breakthrough that Houston’s ecosystem is built to produce,” Paul Wotton, managing partner of RBL LLC and co-founder of Duracyte, added in the release. “With world-class clinical infrastructure, exceptional engineering talent and initiatives like the Texas Biotech Task Force driving alignment across industry, investment and talent, this region is uniquely positioned to move the most ambitious ideas in medicine from concept to patient, faster than anywhere else.”