3 Houston innovators to know this week

who's who

This week's roundup of Houston innovators includes Jason Pesterfield of Optellum, Jane Stricker of HETI, and Michael Lee of Octopus Energy. Photos courtesy

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — from health tech to clean energy — recently making headlines in Houston innovation.

Jason Pesterfield, CEO of Optellum

Jason Pesterfield joins the Houston Innovators Podcast to share how he plans on getting the company to commercialization right here from Houston. Photo courtesy of Optellum

Last year, Optellum, based in the United Kingdom, opened its United States headquarters in Houston, and shortly after Jason Pesterfield joined to lead the team. On a recent Houston Innovators Podcast episode, Pesterfield explained it's just the start of the company's presence in Houston.

"We're really at the beginning of it," he says. "This is the epicenter of medicine within the United States. There's no bigger or better place for health care than Houston. It's great to be a part of that and to have access to those facilities and those world class physicians and care teams." Read more.

Jane Stricker, executive director of the Houston Energy Transition Initiative at the GHP

These organizations are teaming up to advance development of a regional clean industrial hub. Photo courtesy of GHP

The Houston Energy Transition Initiative and the Center for Houston’s Future have teamed up with the Mission Possible Partnership to lead the city of Houston through the accelerated development of a regional clean industrial hub geared at decarbonization of the industrial sector, including petrochemicals, cement plants, heavy transportation, and more.

The two-year project is focused on development and deployment of clean energy projects — such as "low-carbon hydrogen, carbon capture, use and storage, electrification of industrial processes, and the production and use of low carbon fuels," according to a press release.

“There is no geography in the world better positioned to support the transition to and integration of abundant, low-carbon energy solutions than Houston," says Jane Stricker, executive director and senior vice president of HETI, in the release. "As the Energy Transition Capital of the World, Houston is leveraging its energy leadership to accelerate global solutions for a low-carbon future. This partnership with MPP is a critical component in the region’s efforts to develop and deploy technologies, policies and strategies for broad decarbonization." Read more.

Michael Lee, CEO of Octopus Energy US

Now is the time for your tech company to become a climate company, says this Houston expert. Photo via LinkedIn

In a guest column for InnovationMap, Michael Lee, CEO of Octopus Energy, called for tech innovators to change lanes to focus on the climatetech industry.

"We used to say, 'every company will become a tech company.' We’re now moving towards a world where 'every company is a climate company,'" Lee writes. "And that is creating opportunities throughout the economy for people to contribute their skills and support their families while building something that actually matters." Read more.

Jason Pesterfield, CEO of Optellum, joins the Houston Innovators Podcast to share how he plans on getting the company to commercialization right here from Houston. Photo courtesy of Optellum

Houston innovator gears up for commercialization for AI-driven lung cancer diagnostic tool

HOUSTON INNOVATORS PODCAST EPISODE 164

When a United Kingdom-based, artificial intelligence-driven lung cancer detection tool opened its United States headquarters in Houston, the company tasked Jason Pesterfield with the role of CEO to oversee international expansion and commercialization strategy. Pesterfield, who's based out of the Texas Medical Center's Innovation Institute, is familiar with the job he's been hired to do — that's because he's done it before.

After spending almost two decades at medical technology company, Stryker, Pesterfield joined St. Louis-based Veran Medical Technologies, a company also focused on lung cancer detection, and grew the business over 8 years years to a $30 million-plus annual revenue company before it was acquired by Olympus Corp. in 2020.

After assisting with the transition, he was approached by U.K.-based Optellum's Founder Timor Kadir about taking the reins of Optellum last year to again help scale the early stage digital health company.

"I'm not a computer scientist or an algorithm guy, but I do have experience in commercialization, leading teams, building culture, acquire great talent, working with my team to build a great strategy, and working with investors to make sure we're in a good financial position," Pesterfield says on the Houston Innovators Podcast.

Optellum was founded in 2016, and first entered the Houston market by way of the TMC's accelerator program and its BioBridge with the U.K. The company's technology is an AI platform that helps practitioners diagnose and treat early-stage lung cancer. The software uses natural language processing to scan medical reports of nodules in the lungs to give health care providers more information on cancer diagnostics — an analysis that takes just seconds.

"It's like having a hundred thousand sets of eyes looking over a physician's shoulder," Pesterfield says.

In September, the company raised a $14 million series A round of funding, and Pesterfield explains how that funding is being deployed to focus on growing teams within sales, B2B support, and its research and development pipeline.

He explains on the show that Optellum is just getting started with its relationship within the Houston innovation ecosystem. Pesterfield says Optellum is even on the path to securing its first Houston-based customer.

"We're really at the beginning of it," he says. "This is the epicenter of medicine within the United States. There's no bigger or better place for health care than Houston. It's great to be a part of that and to have access to those facilities and those world class physicians and care teams."

Pesterfield share more on Optellum's future on the podcast. Listen to the interview below — or wherever you stream your podcasts — and subscribe for weekly episodes.

Optellum, Liongard, and Cart.com have hired new members to their executive teams. Photos courtesy

Updated: 3 Houston startups make strategic C-suite hires

short stories

A handful of Houston tech startups have recently announced new appointments to their C-suites. A med tech company with its national headquarters in Houston has a new leader, a Houston software has a new exec focused on strategy, and a e-commerce company has a new chief revenue officer.

Optellum names new CEO

Jason Pesterfield will lead United States operations for Optellum. Photo courtesy of Optellum

Optellum, a medical software startup based in the United Kingdom and has its United States HQ in Houston, has appointed Jason Pesterfield as CEO to lead growth in the U.S. clinical market. Optellum AI-based software enhances early lung cancer diagnosis and therapy with its medical device software platform, Virtual Nodule Clinic.

Pesterfield was previously the president and CEO of Veran Medical Technologies, a leader in image-guided lung cancer diagnosis. He brings 25 years of leadership experience in the medtech sector. Optellum was founded by Václav Potěšil, Lyndsey Pickup, Timor Kadir, Professor Sir Mike Brady, and Jérôme Declerck.

"It took us almost a year to find the right successor who shares our vision and has the right expertise to take Optellum on to the next stage of growth," says Potěšil in a news release. "I am really excited to work with Jason, to make Optellum's platform available to every clinician in the USA and around the world, and to help them diagnose their lung cancer patients as early as possible. With Jason on board, I can focus on advancing Optellum's vision to transform early lung cancer therapy through partnerships that harness the power of AI software combined with molecular diagnostics, robotics and interventional devices, and drugs."

Liongard announces chief strategy officer

Patrick Schneidau is the chief strategy officer for Liongard. Photo courtesy

​Houston software-as-a-service company, Liongard, has named Patrick Schneidau as chief strategy officer. The company, founded in 2015, was a 2021 InnovationMap Awards finalist and reported that the team was looking to expand by around 70 new hires over the next year.

"Liongard is an incredible Houston growth story," Schneidau tells InnovationMap. "Our founders, Joe Alapat and Vincent Tran, have built a first-class team that allow technology service providers to operate at 10x by providing unprecedented insight and data into the systems deployed in the modern IT stack. In a rapidly growing market, they are quickly becoming 'must have' technology. I'm excited to join to team to accelerate their growth into new markets and with new products."

Schneidau spent over a decade at Houston-based PROS before serving in C-level positions at two other Houston startups — Commtrex and Truss. He's also previously served as talent committee chair for Houston Exponential.

Cart.com hires a new chief revenue officer

Randy Ray is Cart.com's first chief revenue officer. Photo courtesy of Cart.com

Fresh off its $98 million series B, Cart.com has named its first chief revenue officer. Randy Ray is tasked with driving sales growth across the company. He has over 15 years of sales and operations experience and was previously senior vice president at supply-chain solution provider High Jump.

"I've worked with the world's biggest retail and SaaS brands, and I've seen the need for a unified Ecommerce-as-a-Service hub to create operational efficiencies and unlock scalable success," Ray says in a press release. "I'm a firm believer in the Cart.com mission to drive success for online brands, and I'm looking forward to tripling our sales organization and building out a world-class revenue infrastructure as we take the company global over the next 6 to 9 months."

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Houston startup funding surpasses $1B in 2025 despite national slowdown

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Houston-area startups raised more than $1 billion in venture capital during the first half of 2025 — almost double the haul for the first half of last year.

According to the new PitchBook-NCVA Venture Monitor, Houston-area startups raised $417.2 million in the second quarter of this year, compared with $281 million during the same period last year. In the first quarter of 2025, local startups collected $607.5 million in venture capital, compared with $281 million during the same period a year earlier.

Based on those figures, Houston-area startups picked up slightly over $1 billion in VC during the first half of this year, compared with $535 million in the first half of 2024.

Nationally, startups gained almost $70 billion in VC in the second quarter, down 25 percent from the same period a year ago, the PitchBook-NCVA Venture Monitor says.

Nizar Tarhuni, executive vice president of research and market intelligence at PitchBook, explained that “the VC landscape continues to navigate a fragile recovery” and is constrained by economic uncertainty.

However, startups in certain sectors are poised to attract a great deal of attention and venture capital over the next several years, according to the report.

“Companies operating in AI, national security, defense tech, fintech, and crypto — sectors aligned with the administration’s priorities — are attracting disproportionately more investor interest, and this trend will likely continue throughout President Donald Trump’s term,” the report says.

The AI sector accounted for 64 percent of VC deal value in the first half of 2025, according to the report.

2 Houston universities among world's best and more innovation news to know

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Editor's note: We're looking back at the biggest Houston business and innovation news from the first half of July. From the world's best universities to innovative cybersecurity staffing, catch up on the top InnovationMap stories from July 1-15 below:

2 Houston universities declared among world’s best in 2026 rankings

Rice is the No. 2 best school in Texas, and No. 119 in the world. Photo via Rice University

Two Houston universities are in a class of their own, earning top spots on a new global ranking of the world's best universities.

Rice University and University of Houston are among the top 1,200 schools included in the QS World University Rankings 2026. Ten more schools across Texas make the list. Continue reading.

Texas cybersecurity co. expands unique train-to-hire model to Houston

San Antonio-based Nukudo is bridging the global cybersecurity talent gap through immersive training and job placement in Houston. Photo via Getty Images

It’s increasingly more difficult to ensure the confidentiality, integrity, and availability of proprietary data and information in the ever-changing, ever-evolving digital world. Cyberattacks, including malware, phishing, and ransomware, are becoming increasingly common and sophisticated, posing a consistent threat to a company’s sustainability and bottom line.

To combat that trend, Nukudo, a San Antonio-based cybersecurity workforce development company, is expanding its initiative to bridge the global cybersecurity talent gap through immersive training and job placement to Houston. Continue reading.

Houston hospital performs first fully robotic heart transplant in the U.S.

Dr. Kenneth Liao and a team at Baylor St. Luke’s Medical Center used a surgical robot to implant a new heart in a 45-year-old male patient. Photo courtesy Baylor College of Medicine.

A team at Baylor St. Luke’s Medical Center, led by Dr. Kenneth Liao, successfully performed the first fully robotic heart transplant in the United States earlier this year, the Houston hospital recently shared.

Liao, a professor and chief of cardiothoracic transplantation and circulatory support at Baylor College of Medicine and chief of cardiothoracic transplantation and mechanical circulatory support at Baylor St. Luke’s Medical Center, used a surgical robot to implant a new heart in a 45-year-old male patient through preperitoneal space in the abdomen by making small incisions. Continue reading.

New Houston biotech co. developing capsules for hard-to-treat tumors

Sentinel BioTherapeutics is developing cytokine interleukin-2 (IL-2) capsules to fight many solid tumors. Photo via Getty Images.

Houston company Sentinel BioTherapeutics has made promising headway in cancer immunotherapy for patients who don’t respond positively to more traditional treatments.

The team sees an opportunity to use cytokine interleukin-2 (IL-2) capsules to fight many solid tumors for which immunotherapy hasn't been effective in the past. “We plan to develop a pipeline of drugs that way,” Sentinel CEO Rima Chakrabarti says. Continue reading.

Greentown Labs names Lawson Gow as its new Houston leader

Lawson Gow, founder of The Cannon, will lead Greentown Houston. Photo courtesy Greentown Labs.

Greentown Labs has named Lawson Gow as its Head of Houston.

Gow is the founder of The Cannon, a coworking space with seven locations in the Houston area, with additional partner spaces. According to Greentown, Gow will "enhance the founder experience, cultivate strategic partnerships, and accelerate climatetech solutions" in his new role. Continue reading.

Houston space companies land $150M NASA contract for vehicles and robots

space simulations

Houston-based MacLean Engineering and Applied Technology Services LLC, known as METECS, has received a five-year contract from NASA to develop simulations and software services for space-based vehicles and robots, with a maximum value of $150 million.

Two other Houston-area companies, Tietronix Software Inc. and Vedo Systems LLC, were assigned as subcontractors for the award.

"This award is a strong testament to NASA’s continued trust in the quality of our work and their confidence in our ongoing support of the human spaceflight program," John MacLean, president of METECS said in a release.

According to NASA, the awardees are tasked with providing:

  • Simulation and software services for space-based vehicle models and robotic manipulator systems
  • Human biomechanical representations for analysis and development of countermeasure devices
  • Guidance, navigation, and control of space-based vehicles for all flight phases
  • Space-based vehicle on-board computer systems simulations of flight software systems
  • Astronomical object surface interaction simulation of space-based vehicles
  • Graphics support for simulation visualization and engineering analysis
  • Ground-based and onboarding systems to support human-in-the-loop training

The contract is called Simulations and Advanced Software Services II (SASS II), and begins in October. This is the second time METECS has received the SASS award. The first also ran for five years and launched in 2020, according to USASpending.gov.

METECS specializes in simulation, software, robotics and systems analysis. It has previously supported NASA programs, including Orion, EHP, HLS, Lunar Gateway and Artemis. It also serves the energy, agriculture, education and construction sectors.

Tietronix Software has won numerous awards from NASA. Most recently, it won the NASA JSC Exceptional Software Award (2017). Some of its other customers include Houston Independent School District, Baylor College of Medicine, DARPA and Houston Methodist.

Video Systems offers software for implementing human-rated, AI and autonomous systems, as well as engineering services to address the needs of spaceflight and defense. The company has previously worked with NASA and METECS, as well as Axiom Space and defense contractor Lockheed Martin.

The three companies are headquartered near NASA’s Johnson Space Center in Houston.

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