There are three key things every faculty who wants to start a company should think about. Graphic by Miguel Tovar/University of Houston

Trying to start a business as a faculty member in academia? Don't fret. As daunting as starting a company can seem, this blog will aim to give any prospective entrepreneur useful insights to getting started.

Jason Eriksen, Ph.D., an associate professor of Pharmacology at the University of Houston, has founded three different Biotech companies since he's been at UH: Alzeca Biosciences, Teomics, and Swift Front.

Alzeca was the first company he co-founded with Dr. Ananth Annapragada, from Texas Children's Hospital back in 2009.

"The mission of Alzeca is to develop an inexpensive non-invasive diagnostic test for the detection of Alzheimer's disease and other neurodegenerative disorders," Eriksen said.

The second company was Teomics that he founded to "develop better diagnostic tools for scientific and medical research."

Finally, the third, and most recent, startup Eriksen founded was Swift Front.

"The mission of Swift Front is to develop a fully automated high-speed microscope platform that can be used to generate three dimensional images of whole organs or other huge objects at speeds 1000 to 10,000 times faster than what's commercially available today," he said.

According to Eriksen, there are three key things every faculty who wants to start a company should think about:

1. Mind the culture gap

Scientists evaluate research by considering whether it makes an original contribution to our understanding of the world. Businesses have a different rationale, which, by and large, is to make money. This engenders a huge culture gap. Your greatest, latest discovery in the lab may have no immediate practical application, and will never be of interest to businesses, unless it has the opportunity to become commercialized. As opposed to a company with an established business model, startup companies like yours will have neither an established technology, nor an established base of customers. As a founder of a startup, your primary mission is to identify who is going to buy your technology, and why they are going to buy it. Get out of the building to discover your customers.

2. Remember there is no single path to commercialization

It's a very long road from an idea in the lab to a commercial success. There are many ways to go from the laboratory bench to the store, and commercialization is just like any business process. It's part art, and part science; part inspiration and part perspiration. There are no shortcuts to becoming successful. So, if anyone tells you at the start that your idea is a guaranteed winner (or not), don't believe them. There is a lot of hard work that has to be done to see if an idea can make it.

3. Stay self-funded as long as possible

Starting a business is one of the hardest things you'll ever do. It takes time, energy, and money… a whole lot of money. More money than you have in your bank account (probably). Does that mean you need to find an investor? No. Avoid taking investments too early in the company. Whether you head to the bank, call a rich family friend, or tap an investor, you give up control as soon as you hold out your hand for money. Retain control of your business's money, and you will keep control of your business.

Money is the Biggest Obstacle

Obstacles are inevitable when starting a new business. "Money makes the world go round, and one of the most challenging obstacles for any new company is to have enough money to keep moving forward," Eriksen said.

Eriksen said his first company, Alzeca, was "self-funded for several years." In order to move the company forward, they needed to seek non-dilutive forms of funding to develop their technology.

Types of Non-Dilutive Funding

  • Grant Awards
  • Bank loans
  • (Forgivable) Loans from Family and Friends
  • Licensing and Royalties from Products
  • Tax Credits
  • Crowdfunding

Eventually, Eriksen and his team at Alzeca were ready for human trials and needed millions of dollars to do so.

"By this point, we were fortunate that we had an excellent team of founding members, consisting of myself, Dr. Annapragada, a founder with deep business experience and a CEO who did a lot of the actual fundraising for us. Together, the team was able to recruit investors with deep pockets, allowing us to move this technology forward," Eriksen said.

Basic Checklist for Starting a Company

Beyond understanding the larger concepts behind starting a company and that money is essential, here are a few things to remember, according to Eriksen:

  1. Ask other entrepreneurs for advice
  2. Identify your target audience/customers
  3. Believe in your idea and don't let anyone tell you otherwise. Work hard and see for yourself if the idea will work
  4. Seek out what resources your university offers for entrepreneurs
  5. Avoid taking investments too early in the company. Retain control of your business's money, and you will keep control of your business.
  6. When it's time to expand, use non-dilutive types of funding
  7. Have a strong team behind you that wants to see the company succeed

What's The Big Idea?

Any aspiring entrepreneur who is considering starting a new company, but has no previous experience, should ask other entrepreneurs for advice. UH offers a number of programs that support faculty entrepreneurs such as the regional iCorps program and a growing Office of Technology Transfer and Innovation at the UH Technology Bridge. Be sure to check out your technology transfer office at your university to see what programs are available to support you as you get started.

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This article originally appeared on the University of Houston's The Big Idea. Cory Thaxton is the communications coordinator for The Division of Research.

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Houston leaders form coalition to boost Texas power grid with new tech

a better grid

A Houston-based coalition that launched this month aims to educate Texas officials about technology designed to shore up the state’s power grid.

The public-private Texas Reliability Coalition says it will promote utility-scale microgrid technology geared toward strengthening the resilience and reliability of the Texas power grid, particularly during extreme weather.

A utility-operated microgrid is a group of interconnected power loads and distributed energy sources that can operate in tandem with or apart from regular power grids, such as the grid run by the Electric Reliability Council of Texas (ERCOT). Legislation passed in 2023 enables the use of utility-scale microgrid technology in Texas’ deregulated energy market, according to the coalition.

John Elder, executive director of the coalition, says that with the legal framework now in place, the Public Utility Commission of Texas and ERCOT need to create rules to establish the Texas marketplace for microgrid technology. The goal, he says, is to “take the Texas grid from good to great” by installing microgrid technology, improving the infrastructure, and strengthening the system — all targeted toward meeting power needs during extreme weather and amid growing demand.

Houston-based CenterPoint Energy will test the utility-scale microgrid technology being promoted by the coalition. In a January 31 filing with the Public Utility Commission, CenterPoint says microgrid technology will be featured in a $36.5 million pilot program that’ll set up an estimated three to five microgrids in the company’s service area. The pilot program is slated to last from 2026 to 2028.

In the public affairs arena, five Houston executives are leading the new reliability commission’s microgrid initiative.

Elder, one of the coalition’s founding members, is president and CEO of Houston-based Acclaim Energy. Other founders include Ember Real Estate Investment & Development, Park Eight Development, and PowerSecure. Ember and Park Eight are based in Houston. Durham, North Carolina-based PowerSecure, which produces microgrid technology, is a subsidiary of energy provider Southern Co.

Aside from Elder, members of the coalition’s board are:

  • Stewart Black, board secretary of the coalition and vice president of Acclaim Energy’s midstream division
  • Todd Burrer, president of municipal utility districts at Inframark
  • Harry Masterson, managing principal of Ember
  • Martin Narendorf, former vice president at CenterPoint Energy

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This article originally appeared on our sister site, EnergyCapital.

This Houston neighbor is the fastest growing wealthy suburb in America

By The Numbers

The Houston-area city of Fulshear is booming like nowhere else: It's now the No. 1 fast-growing affluent suburb in the country.

Fulshear's No. 1 status was unveiled in a new GoBankingRates' study that ranked the "30 Fastest Growing Wealthy Suburbs in America" for 2025. The report examined population changes from 2018 to 2023 among cities and towns in major U.S. metro areas with populations between 25,000 and 100,000 residents. Median household income, average home value, and a "livability score" were also calculated for each locale.

Fulshear, located 34 miles west of downtown Houston, experienced the most dramatic population increase out of all 30 cities in the report. Though the suburb only has an estimated population of 42,616 residents, that number has skyrocketed 237 percent during the five-year period.

A Fulshear resident's median income is $178,398 annually, and the average value of a home in the city comes out to $521,157, the report additionally found.

Fulshear was the second fastest growing city in America in 2023. The city's growth is further reflected by the number of new apartments that were built in the area in 2024.

Texas is tops
Texas cities took the top three fastest growing U.S. suburbs for 2025, with Dallas-area cities of Celina (No. 2) and Prosper (No. 3) experiencing wildly different (yet still sky high) population changes. Celina's population ballooned 190 percent to 43,317 residents, while Prosper's grew 81 percent to an estimated 41,660 people.

Other Texas cities that earned spots in the report include Flower Mound (No. 19), Southlake (No. 27), University Park (No. 28) and Colleyville (No. 29), all in the Dallas-Fort Worth area.

"The old adage that everything is bigger in Texas is true, considering the number of Lone Star State suburbs that are quickly growing in population and overall wealth," the report's author wrote.

The top 10 fastest growing wealthy suburbs in America are:

  • No. 1 – Fulshear, Texas
  • No. 2 – Celina, Texas
  • No. 3 – Prosper, Texas
  • No. 4 – Erie, Colorado
  • No. 5 – Clarksburg, Maryland
  • No. 6 – Zionsville, Indiana
  • No. 7 – Redmond, Washington
  • No. 8 – Dublin, California
  • No. 9 – Parkland, Florida
  • No. 10 – Eastvale, California
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This story originally appeared on our sister site CultureMap.com.

Rice research breakthrough paves the way for advanced disease therapies

study up

Bioengineers at Rice University have developed a “new construction kit” for building custom sense-and-respond circuits in human cells, representing a major breakthrough in the field of synthetic biology, which could "revolutionize" autoimmune disease and cancer therapeutics.

In a study published in the journal Science, the team focused on phosphorylation, a cellular process in the body in which a phosphate group is added to a protein, signaling a response. In multicellular organisms, phosphorylation-based signaling can involve a multistage, or a cascading-like effect. Rice’s team set out to show that each cycle in a cascade can be treated as an elementary unit, meaning that they can be reassembled in new configurations to form entirely novel pathways linking cellular inputs and outputs.

Previous research on using phosphorylation-based signaling for therapeutic purposes has focused on re-engineering pathways.

“This opens up the signaling circuit design space dramatically,” Caleb Bashor, assistant professor of bioengineering and biosciences and corresponding author on the study, said in a news release. “It turns out, phosphorylation cycles are not just interconnected but interconnectable … Our design strategy enabled us to engineer synthetic phosphorylation circuits that are not only highly tunable but that can also function in parallel with cells’ own processes without impacting their viability or growth rate.”

Bashor is the deputy director for the Rice Synthetic Biology Institute, which launched last year.

The Rice lab's sense-and-respond cellular circuit design is also innovative because phosphorylation occurs rapidly. Thus, the new circuits could potentially be programmed to respond to physiological events in minutes, compared to other methods, which take hours to activate.

Rice’s team successfully tested the circuits for sensitivity and their ability to respond to external signals, such as inflammatory issues. The researchers then used the framework to engineer a cellular circuit that can detect certain factors, control autoimmune flare-ups and reduce immunotherapy-associated toxicity.

“This work brings us a whole lot closer to being able to build ‘smart cells’ that can detect signs of disease and immediately release customizable treatments in response,” Xiaoyu Yang, a graduate student in the Systems, Synthetic and Physical Biology Ph.D. program at Rice who is the lead author on the study, said in a news release.

Ajo-Franklin, a professor of biosciences, bioengineering, chemical and biomolecular engineering and a Cancer Prevention and Research Institute of Texas Scholar, added “the Bashor lab’s work vaults us forward to a new frontier — controlling mammalian cells’ immediate response to change.”