The Ion named three corporate partners ahead of its annual innovation-focused festival. Photo courtesy of the Ion

Houston’s Ion innovation hub has recruited three heavyweight corporate partners, the hub announced earlier this week.

The new partners are:

  • Houston-based energy company Occidental (known as Oxy).
  • United Airlines Ventures, the sustainability-focused VC arm of Chicago-based United Airlines. United operates a major hub in Houston.
  • Australia-based Woodside Energy, which maintains an office in Houston.

Oxy, United Airlines Ventures, and Woodside will share their expertise in support of Ion’s mission to transform Houston into a global innovation ecosystem, according to an Ion news release. In addition, they will participate in Ion programming and network with Ion affiliates. Executives from all three of the new partners will serve on the Ion Leadership Advisory Roundtable.

“Welcoming our newest partners into Ion’s ecosystem is a further testament to our momentum in the aerospace and energy transition,” says Jan Odegard, who became executive director of the Ion in 2021 after a year of holding the interim position. “Each organization brings their own culture of innovation that aligns with what we are doing at the Ion.”

Michael Leskinen, president of United Airlines Ventures, says the VC firm believes “the Ion will be the epicenter for Houston’s rapidly growing innovation community — a one-stop shop to share ideas, foster startups, and to develop relationships with Houston’s brightest companies and academia.”

Oxy, United Airlines Ventures, and Woodside join Ion corporate partners such as:

  • Aramco Americas
  • Baker Botts
  • BP
  • Chevron
  • ExxonMobil
  • Global Custom Commerce
  • Intel
  • Microsoft
  • Transocean

The Ion announced the new corporate partners in advance of the second annual Ion Activation Festival, set for May 17-19. The Ion and Rice Management Co. host the festival, which shines a spotlight on entrepreneurship and innovation in Houston.

Activities will take place primarily at the Ion’s 16-acre campus. To register for the festival, visit the Ion’s website.

The inaugural festival, held in 2022, drew more than 2,500 attendees.

Check out these conferences, pitch competitions, networking, and more in the month of May. Photo via Getty Images

10+ can't-miss Houston business and innovation events for May

where to be

It's time to look at what's on the agenda for May for Houston innovators — from pitch competitions to networking events.

Here's a roundup of events not to miss this month. Mark your calendars and register accordingly.

Note: This post might be updated to add more events.

May 1-4 — Offshore Technology Conference

Since 1969, OTC has served as a central hub convening the best and brightest minds in the world to share ideas, and innovations and discuss, debate, and build consensus around the most pressing topics facing the offshore energy sector.

The event is Monday, May 1, to Thursday, May 4, at NRG Park. Click here to register.

May 2 — EDGE Technology Showcase 2023: Delivering the Future

Oceanit’s 2023 EDGE Technology Showcase will run alongside Houston's Offshore Technology Conference, the Oceanit EDGE Technology Showcase event will feature technologies that are delivering the future, from deep sea to deep space — from disruptive innovations to scalable turnkey solutions.

The event is Tuesday, May 2, from 5:30 to 8:30 pm, at 1940 Air Terminal Museum. Click here to register.

May 3 — Women, Wine & Web Design - Houston

Create a web page, enjoy some wine, and network with like-minded Houston area women.

The event is Wednesday, May 3, from 5:30 to 8:30 pm, at Improving (10111 Richmond Ave.). Click here to register.

May 10 — Energy 2.0 UN-Conference - NetZero: A Race We Can All Win

Energy 2.0 is the UNconference where we celebrate diverse perspectives, technologies, and people driving the energy transition forward.

The event is Wednesday, May 10, from 8 am to 5 pm, at Woodside Energy (1500 Post Oak Blvd.). Click here to register.

May 11 — Investor Studio Series Dream Big Ventures x Ion

Hear from experts Staci Latoison, founder of Dream Big Ventures; Ramona Ortega, founder and CEO of WealthBuild.ai; and Nan Almodovar, CEO & broker.

The event is Thursday, May 11, from 5 to 7 pm, at the Ion. Click here to register.

May 11-13 — Rice Business Plan Competition

With access to mentors, real-world experience and investment opportunities, the Rice Business Plan Competition helps student founders stay on target and realize their potential. Click here to see the 2023 teams.

The event is Thursday, May 11, to Saturday, May 13, at Rice University. Click here to register.

May 12 — Linkedin Profile Refresh Workshop

This event is not just about learning new tips and tricks; it's about putting them into practice right then and there.

During the workshop, you'll have the opportunity to work on your LinkedIn profile in real-time, making changes and optimizing it for more visibility and opportunities.

The event is Friday, May 12, from 8:30 to 10:30 am, at the Ion. Click here to register.

May 17 — Engage VC: Scale Venture Partners

Alex Niehenke, Partner at Scale Venture Partners is coming to Houston and will be featured in our fireside chat moderated by Emily Hak, Managing Director, Private Capital Markets at Insperity.

The event is Wednesday, May 17, from 8:30 to 10:30 am, at the Ion. Click here to register.

May 17-19: Ion Activation Festival

Ion District is celebrating its second annual festival of innovation in Houston, known as Activation Festival which will feature:

  • A multi-day showcase of Ion District + Ion and its innovation ecosystem partners
  • An array of futuristic activations and programs alongside a lineup of engaging keynote speakers and experiences
  • A community-wide block party Friday to celebrate the heart of Houston's new innovation district

The event is Wednesday, May 17, to Friday, May 19, at The Ion. Click here to register.

May 18 — Softeq Venture Studio Houston Investor Demo Day: H1 2023 Cohort

At the Houston Investor Demo Day, founders will give their 3-minute pitch, followed by a networking session where you may get a demo of their product and ask any questions. We need you there to evaluate them for investment and give them feedback! Afterward, happy hour and dinner.

The event is Thursday, May 18, from 3 to 7 pm, at Fleming's Steakhouse (CityCentre). Click here to register.

May 23 — Houston Veterans In Residence Showcase

Bunker Labs’ Veterans in Residence Showcase is a nationwide event, celebrating our program participants as they have completed Bunker Labs' six month Veterans in Residence Program.

The event is Tuesday, May 23, from 6 to 8 pm, at Impact Hub Houston. Click here to register.

May 25 — Greentown Houston + BCG X Pitch Day

Join Greentown Houston and BCG X for a pitch competition featuring Greentown startups that are raising their pre-seed and seed rounds to grow their networks and scale their cutting-edge climatetech solutions. The winners will walk away with a total of $10,000 in cash prizes and services support from BCG X. We will also have a Fan Favorite prize, sponsored by O'Melveny who will provide in-kind service in the form of 5 hours of virtual 1:1 office consult on general corporate matters.

The event is Thursday, May 25, from 3:30 to 7:30 pm, at Greentown Houston. Click here to register.

May 30-31 — Women in Tech Texas

Discover the technologies in today's quickly changing world and learn new forward-thinking concepts in business and the workforce that will radically change our future. Join over 1,000 leading women in technology and diversity champions driving the innovation revolution to pioneer the future of technology and business.

The event is Tuesday, May 30, to Wednesday, May 31, at the Hyatt Regency. Click here to register.

May 31 — Demystifying Startup Impact Investing: SWAN Impact Network

SWAN Impact Network is joining the startup ecosystem in Houston. Join the organization for a panel with local thought leaders on "Demystifying Startup Impact Investing” and a time for networking over light bites and drinks. SWAN is an angel network whose members put their money to work to make a difference by enabling creative entrepreneurs with solid plans for financial success to address the world’s most pressing problems.

The event is Wednesday, May 31, from 6 to 7:30 pm, at Ion Houston. Click here to register.

Ad Placement 300x100
Ad Placement 300x600

CultureMap Emails are Awesome

Houston researchers report promising first in-human trial for implantable cancer therapy

cancer breakthrough

When it comes to cancer remedies, the treatment can be as challenging for the body as its cause. But what if immunotherapy could be localized? That’s precisely what a Houston team may soon make a reality.

Rice University researchers, in partnership with MD Anderson Cancer Center, recently published their findings from the first in-human trial of an implantable cancer-fighting treatment in the journal Clinical Cancer Research. The paper details testing of AVB-001, encapsulated cells engineered to release interleukin-2 (IL-2)—a naturally occurring signaling protein that boosts immunity—in the peritoneal cavities of 14 patients. The goal is to avoid the toxicity usually experienced with less targeted treatments, as well as find a solution to IL-2s’ abbreviated half-lives.

“Traditional IL-2 therapy has shown potent antitumor activity, but its clinical use has been limited by severe side effects and delivery challenges,” Omid Veiseh, director of the Rice Biotech Launch Pad, professor of bioengineering at Rice and a senior author on the study, said in a press release. “This platform allows us to localize and sustain cytokine exposure directly where tumors reside while minimizing systemic toxicity.”

Serous ovarian carcinoma is especially well-suited to the use of AVB-001 because it tends to spread throughout the abdomen. After a minimally invasive laparoscopic procedure, patients implanted with the cells were noted to tolerate the treatment well. Half of the enrolled patients’ cancer was stabilized, with several among them reporting extended signs of benefit. No maximum tolerated dose was reached and there were no life-threatening events tied to the study.

If that sounds like less-than-earth-shaking results, this is only the beginning. The capsules were implanted for about one week because IL-2 activity drops off after that. The researchers now know that further testing should include either higher levels, repeated doses, or a combination thereof, in order to create stronger advances.

The team has already made early headway on this next step. Preclinical studies in nonhuman primates were not only tolerated well, but without added toxicity, the apes had consistent pharmacological effects.

“This is a foundational step,” Veiseh explained. “We now have evidence that the platform is safe, biologically active and potentially scalable. The next phase is optimizing dosing and exploring combination therapies to unlock its full clinical potential.”

The combination would also include a checkpoint inhibitor, which might improve AVB-001’s tumor-fighting power. “What is exciting is that we are not just delivering a drug, we are programming a microenvironment,” added Dr. Amir Jazaeri, professor of gynecologic oncology at MD Anderson, member of the Rice Biotech Launch Pad’s clinical advisory board and a senior author on the study. “This opens the door to combination strategies that could amplify immune responses in ways that have not been feasible before.”

Houston startup raises $6M to scale home-based healthcare platform

fresh funding

As healthcare systems race to expand care beyond hospitals and into the home, investors are placing bigger bets on the infrastructure needed to make that shift possible.

This month, Rosarium Health announced it has raised $6 million in seed funding led by Kalos Ventures, with participation from ResilienceVC, Rock Health Capital, Symphonic Capital, Black Tech Nations Ventures and others.

The investment will help the Houston-based startup continue to build its platform, which features a national network of 800-plus clinicians and 3,000-plus contractors to coordinate home accessibility upgrades and modifications for seniors and people living with disabilities.

For founder and CEO Cameron Carter, the company’s mission grew out of firsthand caregiving experiences.

“From my own personal caregiving experiences, I realized that the benefits exist on paper, but not in reality,” Carter said in a news release. “Families are being left to figure out the paperwork and installations all on their own, which shouldn’t be how this works.”

While Medicare Advantage and Medicaid plans have expanded coverage for home-based services and accessibility modifications, the logistics behind delivering those services often remain fragmented.

Rosarium’s platform coordinates the entire process, from clinical assessments and referrals to contractor management, documentation, reimbursement and installation.

“A clinician can document that a home isn’t safe and a plan can approve a benefit, but there’s no one that’s responsible for making sure the work actually gets done,” Carter says. “We built the missing piece.”

The company was founded in 2021 as Rose Health and was a 2023 participant in the Texas Medical Center’s Accelerator for HealthTech program. It has scaled quickly, building a network of more than 800 clinicians and 3,000 contractors across 34 states.

Rosarium is currently in-network for 1.2 million Medicare and Medicaid lives, with projected coverage expected to reach nearly 4 million by the end of the year, according to the release.

“We’re excited to back Cameron because he and the team at Rosarium are building the infrastructure healthcare needs right now to make the home a safe and comfortable place of care,” Kate Ballinger, investor at Kalos Ventures, added in the release.

As part of the recent investment, Ballinger will join Rosarium’s board of directors.

With eyes on the future, Rosarium plans to grow its partnerships with Medicaid and Medicare Advantage plans, including CalViva and Community Health Plan of Imperial Valley, strengthening its presence in California while expanding access to underserved communities.

Additionally, Carter predicts that home-based healthcare will be part of a broader transformation happening across the industry.

“There’s a growing recognition that health outcomes are shaped by what happens in the home,” he said in the release. “The future of healthcare isn’t just treating people after something goes wrong. It’s creating environments that help prevent those problems in the first place.”