After winning CodeLaunch last year, Matt Bonasera, enterprise architect at E360, looks forward to the future of the energy tech company. Photo by Natalie Harms/InnovationMap

Houston-based energy efficiency company Energy 360 is working to balance what is often viewed as a tradeoff between high quality clean air and energy efficiency within corporate buildings.

E360 is a subsidiary of InTech Energy, a software company that provides a variety of energy efficiency solutions for commercial spaces. The enterprise architect of E360, Matt Bonasera, says the platform functions as an energy management system as it monitors air quality, greenhouse gas emissions, and can adjust electricity usage among a host of other outputs.

“We are trying to holistically look at each building instead of just looking at it purely from the energy efficiency perspective or purely from looking at it from a health perspective,” Bonasera says.

Bonasera says E360 is the “last mile” in the energy transition, ensuring companies stick to their cost and energy-saving tactics after implementing them via consistent monitoring. E360 also helps users acquire energy efficiency grants from the U.S. government, using the platform to keep corporations accountable to their energy-saving goals.

“The market is really desperate for energy efficiency and there’s a lot of low hanging fruit out there. Only 10 percent of buildings have any energy efficiency mechanisms whatsoever,” Bonasera shares.

Bonasera says E360 predominantly works with corporations that own their own commercial space, particularly charter schools, churches, and Native American reservations. Though the platform is designed to save building-owners money and can assist commercial subletters, Bonasera says E360’s users tend to have a personal interest in their own air quality and emissions, prompting them to use the system.

Bonasera says E360 has the potential to dramatically improve the learning environment in schools since contracting with Stafford ISD and several charter schools. After implementing E360’s air quality monitoring and purifying system, Bonasera said schools experienced a significant drop in absenteeism.

“If you just improve the air quality in the building, students will do better, they will have better grades and we will have better outcomes,” Bonasera says.

After initially rolling their product out in California, Bonasera says E360 is gaining serious traction in the South, particularly in Texas. Following the devastating Winter Storm Uri, Bonasera says there has been increased interest in systems like E360 as Texans are hyper-aware of the delicate state of the energy grid.

“In Texas people are looking for ways to be more energy efficient and self-sufficient and this is a way that we help them,” Bonasera shares.

E360 won the top prize at CodeLaunch, a traveling seed-stage accelerator, in March 2023 and Bonasera says he is excited about what the future holds as they continuously release new updates to the platform.

“I think we’re at an inflection point in the company and I think this is going to be a really pivotal year for us in growth,” Bonasera says.

------

This article originally ran on EnergyCapital.

Ad Placement 300x100
Ad Placement 300x600

CultureMap Emails are Awesome

Houston brain health co. secures $6.5M for rare disease study

neuro funding

Houston-based Goldenrod Therapeutics, part of Fannin Partners' portfolio, has announced the initial close of a $6.5 million series seed preferred stock round.

The round was led by Ataxia Ventures and an affiliate of Fannin, according to a news release.

Goldenrod Therapeutics plans to use the funding to support manufacturing, formulation optimization, IND-enabling studies and a Phase I study of its drug to treat brain inflammation, known as 11h.

The study will consider how 11h, which blocks the enzyme PDE4, could treat Friedreich’s ataxia (FA), a rare genetic disease that affects movement, speech and balance. To date, other PDE4 inhibitors have proven to regulate neuroinflammation and neuronal signaling, but have had adverse gastrointestinal side effects or have not reached enough of the central nervous system, according to Goldenrod.

The company says its 11h is expected to have "broad applicability" with limited emetric side effects.

“Our 11h program is a next-generation, orally bioavailable, brain-penetrant PDE4 inhibitor, where researchers overcame longstanding limitations associated with earlier PDE4 inhibitors," Dr. Dev Chatterjee, CEO of Goldenrod, said in the news release. "We believe this creates the potential for a best-in-class therapy for Friedreich’s Ataxia and a potential foundation for development across multiple neurodegenerative and neuroinflammatory disorders.”

11h was first developed at the University of Nebraska Medical Center (UNeMed). Houston-based Fannin Partners in-licensed the product 2020 and landed SBIR Phase I funding to support its initial development for opioid use disorder soon after.

Goldenrod has also received funding to study 11h's effectiveness for multiple sclerosis, methamphetamine addiction and cocaine addiction.

Goldenrod says it is developing 11h to target a variety of neurological and inflammatory conditions, including Alzheimer's disease, multiple sclerosis, ALS, substance use disorders, Batten disease, pain and traumatic brain injury.

27 Houston companies make Fortune 500 for 2026, led by energy giants

Houston HQs

Editor's note: This article has been updated to correct the number of companies based in the Dallas-Fort Worth area.

Houston is a giant among U.S. hubs for corporate headquarters.

The 2026 Fortune 500 lists 27 companies based in the Houston area, with many energy companies claiming top spots. Houston ties with Chicago for the second-most Fortune 500 headquarters, preceded only by New York City (53). Dallas-Fort Worth is home to 24 Fortune 500 headquarters.

Texas leads the nation for Fortune 500 headquarters (57), with California in the No. 2 spot and New York at No. 3.

“Texas is the undisputed headquarters of headquarters,” Gov. Greg Abbott said in a news release. “The world’s leading businesses invest with confidence in Texas because of our welcoming business climate, predictable regulatory environment, and skilled and growing workforce. People and businesses are choosing Texas because Texas works.”

The 2026 Fortune 500 ranks the largest U.S. corporations based on revenue in fiscal year 2025.

Here’s a rundown of the 27 Fortune 500 companies based in the Houston area.

  • No. 9 ExxonMobil
  • No. 21 Chevron
  • No. 29 Phillips 66
  • No.55 Sysco
  • No. 75 ConocoPhillips
  • No. 89 Enterprise Products Partners
  • No. 103 Plains GP Holdings
  • No. 133 Hewlett Packard Enterprise
  • No. 149 NRG Energy
  • No. 157 Quanta Services
  • No. 164 Baker Hughes
  • No. 173 Occidental Petroleum
  • No. 179 Waste Management
  • No. 201 EOG Resources
  • No. 204 Group 1 Automotive
  • No. 207 Halliburton
  • No. 223 Cheniere Energy
  • No. 236 Corebridge Financial
  • No. 262 Targa Resources
  • No. 266 Kinder Morgan
  • No. 388 Westlake
  • No. 435 CenterPoint Energy
  • No. 438 APA
  • No. 440 Comfort Systems USA
  • No. 455 NOV
  • No. 488 KBR
  • No. 496 Coterra Energy. Oklahoma City, Oklahoma-based Devon Energy and Houston-based Coterra Energy merged in early May, with the combined company retaining the Devon Energy name and the Houston headquarters.

The Greater Houston Partnership notes the Houston area soon will welcome its 28th Fortune 500 company. Expand Energy (formerly Chesapeake Energy), appearing at No. 362 on the 2026 list, says it’s moving its headquarters from Oklahoma City to Spring this year.

As the natural gas producer prepares to relocate to Texas, it’s hunting for a new leader. Nick Dell’Osso stepped down as president and CEO earlier this year. Board Chairman Michael Wichterich is interim president and CEO.

Dell’Osso became president and CEO of Oklahoma City-based Gulfport Energy effective May 28.

---

This article first appeared on EnergyCapitalHTX.com.