Looking back on the past few days of low temperatures, ice, snow, power and water outages, and more, it's time to focus on innovation for resilience. Photo courtesy of ABC13

Greater Houston and all of Texas have faced enough persistent challenges over the past seven years that communities and businesses are at a breaking point. Not just financially and economically, but at societal and emotional levels expected from repeated natural and man-made disasters.

Increasingly, the focus on "resilience" as a call to action has become a buzzword rather than measure of performance by public and private sector decision-makers. Simply, our version of resilience is defined as pre-disaster risk mitigation and investment, not recovery and rebuilding after the fact, which is precisely what is being debated across traditional and social media.

As families, small businesses, larger corporations, neighborhoods, and communities require stability, predictability, and frankly reliability, there is now disappointment and disillusion across party lines for our public agencies, programs, officials. When the last major freeze and snowfall hit Texas, the state's power grid ERCOT and the legislature were warned that unless immediate steps were taken to invest in our electrical grid, an expected collapse of the entire system would leave entire cities and potentially the state in darkness with life-threatening consequences. Review any of the published recommendations from previous disasters and each conclusion identifies necessary and urgent investment, re-engineering, and technological innovation. And yet many of those findings are but another can kicked down the road.

While finger-pointing, investigations, hearings, reports, studies can be the actions of our elected and appointed officials, we turn to entrepreneurs, inventors, innovators, and investors as the path forward. Want to add to your blood pressure? Read all the After-Action Reports and Lessons-Learned Analyses — from as far back as Hurricane Andrew to the most recent disasters, including snowstorms, derechos, wildfires, and now COVID-19. Very little changes in these documents regarding the failures of government and/or the significant gaps between alerts, warnings, preparation, response, recovery, rebuilding. More recently, analysis and assessments provided by Wharton at the University of Pennsylvania and the Insurance Information Institute suggest a 1:4+ return on investment for pre-disaster resilience.

Communities often are asked to rely upon hydrological engineering and science as the holy grails in response to our floods, storms, hurricanes. And yet, there is a new "class" of data scientists, analytic tools, curated information, and significant user interfaces that have changed how government, industry, civic, academia and philanthropy can allocate their resources in more efficient and effective ways to unleash innovative resilience. Emerging enterprises and organizations to watch that are driving the "new resilience data science" for entrepreneurs and innovators alike to develop the next generation of insight include Jupiter Intelligence, HazardHub, ResilientGrid, and EcoMetrics.

What is rarely captured in the post-incident studies and gatherings is the powerful impact of the "GSD" networks — "The Get Shit Done" relationships, partnerships, tools and resources mobilized by unleashing innovation! And the good news is that Greater Houston as well as across the nation, a number of companies, products, integrated data-equipment, digital platforms, and best practices have emerged from several innovation ecosystems that should be brought to the forefront of any next steps for community and civic leaders seeking to address a 21st century resilience agenda.

There are the data and platform folks — Umanity, FoodBot, GotSpot, Crowd Source Rescue (all based in Houston) along with Harbor, R3Water, and a host of other national firms — for example that have addressed the speed by which needs, resources, information and actionable intelligence can align to assist volunteers, neighborhoods, philanthropy, and small businesses. As previous senior leadership of FEMA have admitted, the public sector can no longer be the go-to resource during every disaster, incident, and threat.If we are to democratize resilience because no one entity can afford continued losses — such as the insurance and reinsurance sector — nor is there enough taxpayer dollars to fix our critical infrastructure, then we must spark private-philanthropic-public partnerships through innovation.

If COVID -19 taught us anything, it's that we continue to face inventory management supply-chain, and resilient inventory problems that have been identified during and after previous disasters. With blockchain, advanced sensors and monitors, robotics and remote screening, reopening Greater Houston and the US can be done with innovative health technologies such as San Antonio-based Xenex.

In regards to the challenge before us, we must recall that the demand and intersection for an energy, water and data "nexus" began to take off in response to the Texas and California droughts, rose again to the forefront during multiple hurricanes in the US, and are a now the latest critical infrastructure focus in the post snowstorms of 2021.

Why is having Elon Musk's GigaFactory in Texas so vital to resilience innovation? Because the research and product development of batteries to retain solar and wind produced power can directly impact the load-demands in advance of an oncoming weather or worse a cybersecurity threat to the grid. Sunnova — another Houston brand — has been proving the benefit of storage capacity from its work in Puerto Rico and now exhibits the unique performance for future off-grid resilience of homes, medical offices, and vital services.

Until and unless the public sector opens the doors for these and other innovators through immediate and permanent changes in procurement and contracting, strategic partnerships, incentives and credits — while frankly sharing the leadership function with entrepreneurs, inventors, and investors — we will all pay the price for the failure to act.

There is still work to be done from a legislative and governmental perspective, but more and more innovators — especially in Houston — are proving to be essential in creating a better future for the next historic disaster we will face. The Insurance Information Institute's National Resilience Accelerator Initiative and Resilience Innovation Hub Collaboratory (with its flagship in Houston) is working to unleash the best of Texas', the Nation's and the World's best ideas, resources, information and investments.

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Richard Seline is the co-founder of the Houston-based Resilience Innovation Hub.

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3 Houston incubators and accelerators fueling the growth of local startups

Meet the finalists

It takes a village to launch a business. That's where Houston's network of incubators and accelerators can step in, providing the resources, mentorship and community needed to push a fledgling company forward.

As part of our 2026 Houston Innovation Awards, the Incubator/Accelerator of the Year category honors a local organization that is championing and fueling the growth of Houston startups.

Three incubators and accelerators have been named finalists for the 2026 award. They support startups ranging from hard-tech companies to food and youth concepts.

Read more about these organizations below. The 2026 winners will be announced on InnovationMap.com in mid-November.

Activate

Hard tech incubator Activate supports scientists in "the outset of their entrepreneurial journey." The Houston hub was introduced in 2024, and joins others in Boston, New York, and Berkley, California—where Activate is headquartered. It named its third Houston cohort this summer.

The two-year program graduated its first class of Houston fellows in 2026 and saw its first alumni IPO from Houston-based Fervo Energy, which previously participated in a Berkley cohort. Nationally, it has supported 346 fellows and 276 companies since 2015. Those companies have raised more than $6 billion in follow-on funding, according to Activate. In Houston, it has supported Houston startups like Solidec, FlowCellutions and Orbital Arc. Activate Houston is led by managing director Jeremy Pitts, who co-founded Greentown Labs in Boston. It is based out of the Ion.

Impact Hub Houston

Impact Hub Houston supports early-stage ventures at various stages of development through innovative programs that address pressing societal issues. The nonprofit organization supports social impact startups through mentorship, connections and training opportunities.

There are more than 110 Impact Hubs globally with members spanning 72 countries. Launched in 2018, Impact Hub Houston says its membership tripled by the beginning of 2026. This year brought major milestones for the community, including the launch of its Ideas to Impact Accelerator, which supported 11 founders across the health, education, food systems, civic technology and workforce development sectors. It also received funding from more than 20 international Impact Hubs to develop SYNC, a collaboration platform that 25 Impact Hubs across five continents have committed to pilot. The organization has worked with local startups including Myoviva Health, The Change Lab and INNERVERSE Inc.

MarMo Innovation

Galveston-based business incubator MarMo Innovation is focused on removing barriers to entrepreneurship. It aims to provide affordable space, education, mentorship, market access, connections and real-world opportunities that help entrepreneurs move from idea to launch to sustainable growth. The "industry-agnostic" incubator was founded in 2022 and is led by Executive Director Erica Delgadillo.

This year, the organization moved from primarily serving as a coworking and community space into a more comprehensive entrepreneurial incubator by expanding its MarMo Market, MarMo Market Jr. and Lunch LineUp programs. A major focus for MarMo is food entrepreneurship. It is developing an Incubator Kitchen, which MarMo says will support programs like its Cottage to Commercial Bootcamp and Food Biz 101. The organization also expanded its board this year and says it is diversifying its revenue through memberships, events, markets, equipment and space rentals, sponsorships, grants and new entrepreneurial programming.

Baylor College of Medicine launches VC fund to invest in biotech startups

fresh funding

Houston’s Baylor College of Medicine just unveiled a new venture capital fund that backs early-stage biotech startups—and it’s already made its first investment.

BCM Legacy Fund I, funded by philanthropies, invested an undisclosed amount in Houston biotech startup Nemea Therapeutics. Nemea, a spinout of the Baylor College of Medicine and Germany’s Lead Discovery Center, is developing an oral drug to treat metastatic triple-negative breast cancer that no longer responds to currently available therapies.

This type of aggressive cancer spreads from the breast to other areas of the body, such as the bones, liver, lungs or brain. Roughly 38,000 to 57,000 Americans are diagnosed each year with metastatic triple-negative breast cancer. One study showed about half of patients survive past the one-year mark following diagnosis and about one-third survive two years.

“Baylor College of Medicine’s laboratories produce discoveries with the potential to change patients’ lives, and too many of them stall where academic funding ends and private investment has not yet begun,” Dr. Jakub Tolar, president, CEO and executive dean of the Baylor College of Medicine, said in a press release. “The BCM Legacy Fund fills that gap, giving our scientists a path to advance their discoveries to patients.”

The National Institutes of Health awards more than $36 billion per year for biomedical research in the U.S., Baylor said. But some biomedical discoveries “never leave the starting line because they don’t yet fit the economics of venture capital,” the college said.

“The forefront of a new model”

The BCM Legacy Fund aggregates philanthropic capital from private foundations and donor-advised funds. It then invests in startups so they can move beyond that starting line and into later-stage investment rounds. The Greater Houston Community Foundation is the fund’s philanthropic partner.

“It’s exciting to be on the forefront of a new model for philanthropic capital,” said Houston entrepreneur and investor Burton Hanson, managing partner of the fund.

“Not only do we hope to solve a real problem by advancing these therapies to the patients who need them most, but we also hope this model will inspire others in the city and beyond toward philanthropic creativity and a posture of ‘I sacrifice; we win.’”

The fund expects to invest in about 15 early-stage startups over a five-year span. Baylor declined to divulge the amount of money in the fund and the size of the investment in Nemea.

Nemea’s “world-class chemistry”

Hanson oversees the Baylor fund alongside Chicago investor Steve Lehmann, who led the University of Chicago’s Innovation Fund.

Lehmann said Nemea, the fund’s first portfolio company, “has world-class chemistry, Baylor biology, and patients with no good options. Our job is to fund the experiments that carry it to the next handoff, so that industry and later-stage investors can take it from there.”

Based at Houston’s massive Texas Medical Center, Nemea plans to start clinical trials next year in collaboration with Baylor’s Lester and Sue Smith Breast Center.

Nemea previously received $9 million from the Lead Discovery Center and a $1.6 million grant from Baylor. Last year, the startup said it was seeking $25 million to $30 million in seed and Series A funding.

Debra McCoy of Houston, a former managing director at BlackRock and former partner at Bain & Co., and Paul Thomas, co-founder and CEO of Spring-based benefits manager Luscinia Health, sit on the Baylor fund’s governing board. Dr. Paul Klotman, former president, CEO and executive dean of Baylor, is a senior strategic adviser.

How does the fund find investment targets?

The Baylor Legacy Fund relies on two tools to help unearth early-stage biotech startups:

  • High-resolution “innovation maps” of research institutions. These maps surface hidden clusters of innovation, identify rising-star researchers and tie pockets of “innovation supply” at Baylor to areas of “innovation demand” in biotech.
  • AI-enhanced due diligence. AI agents assist with due diligence of early-stage biotech startups. The fund says the platform “distills the frameworks we’ve developed over a decade of teaching and investing into a flexible … diligence environment.”

MD Anderson unveils $3.4B expansion with two new Houston cancer care facilities

major expansion

The cutting edge of cancer-fighting technology and science is getting even sharper after MD Anderson announced last week that it will open two new facilities in the Texas Medical Center within the next five years. Inspiration Tower and Prism will expand MD Anderson’s annual patient load in the TMC to 250,000 annually and will incorporate a variety of new techniques.

The $3.4 billion project will add 2 million square feet to MD Anderson's TMC footprint, bringing its total campus size to 22 million square feet by 2032. Located at the corner of Fannin Street and Holcombe Boulevard, the cancer center says the two new facilities will serve as its new "front door" to the TMC.

“Every detail of these buildings, from the technology to the treatment rooms, was designed around our patients who will receive their care in them and our employees who will work in them. The facilities will serve as a physical representation of hope for the patients and their families who will walk through the doors,” Dr. Jeffrey E. Lee, president ad interim of UT MD Anderson, said in a news release. “Inspiration Tower and Prism are the future of cancer care, and we are grateful for the longstanding support and guidance we’ve received from the UT System Board of Regents to bring these projects to life. These facilities are part of the most impactful capital expansion in UT MD Anderson’s history.”

Prism is especially exciting as it will represent fully half of the linear accelerator treatment in the TMC. Linear accelerator is a radiation treatment that uses magnetically charged fields to deliver targeted external radiation therapy, like shooting cancer with a rail gun. The treatment is safer and has fewer side effects than older radiation treatments.

In addition, Prism will contain 12 MRI machines, four CT scanners, two PET-CT units, 18 radiation vaults and seven radiation simulators. Patient comfort has also been put at a premium with multiple gardens and roof overlooks.

“Every patient we treat deserves an environment that reflects the excellence of the care they receive at UT MD Anderson,” Chris McKee, executive vice president and chief strategy officer at UT MD Anderson, added in the release. “Our new facilities will be innovative, agile, adaptable and beautiful, and they will allow us to care for more patients, more effectively – in an environment that enhances healing and well-being. We are building for our future and for every patient who will be counting on us.”

Prism is slated to open in 2030.

Inspiration Tower will have 25 floors of surgical, diagnostic, and treatment services. At 1.4 million square feet, it’s currently expected to be the largest cancer-specific treatment facility in the United States. The tower will be divided into units for specific types of cancer, making it easy to integrate the advancing research being done all over Houston.

Like Prism, Inspiration Tower is specifically designed to offer comfort and reassurance, with more garden space, terraces, and beautiful scenery to ease patient distress. It is expected to open in 2032.