Looking back on the past few days of low temperatures, ice, snow, power and water outages, and more, it's time to focus on innovation for resilience. Photo courtesy of ABC13

Greater Houston and all of Texas have faced enough persistent challenges over the past seven years that communities and businesses are at a breaking point. Not just financially and economically, but at societal and emotional levels expected from repeated natural and man-made disasters.

Increasingly, the focus on "resilience" as a call to action has become a buzzword rather than measure of performance by public and private sector decision-makers. Simply, our version of resilience is defined as pre-disaster risk mitigation and investment, not recovery and rebuilding after the fact, which is precisely what is being debated across traditional and social media.

As families, small businesses, larger corporations, neighborhoods, and communities require stability, predictability, and frankly reliability, there is now disappointment and disillusion across party lines for our public agencies, programs, officials. When the last major freeze and snowfall hit Texas, the state's power grid ERCOT and the legislature were warned that unless immediate steps were taken to invest in our electrical grid, an expected collapse of the entire system would leave entire cities and potentially the state in darkness with life-threatening consequences. Review any of the published recommendations from previous disasters and each conclusion identifies necessary and urgent investment, re-engineering, and technological innovation. And yet many of those findings are but another can kicked down the road.

While finger-pointing, investigations, hearings, reports, studies can be the actions of our elected and appointed officials, we turn to entrepreneurs, inventors, innovators, and investors as the path forward. Want to add to your blood pressure? Read all the After-Action Reports and Lessons-Learned Analyses — from as far back as Hurricane Andrew to the most recent disasters, including snowstorms, derechos, wildfires, and now COVID-19. Very little changes in these documents regarding the failures of government and/or the significant gaps between alerts, warnings, preparation, response, recovery, rebuilding. More recently, analysis and assessments provided by Wharton at the University of Pennsylvania and the Insurance Information Institute suggest a 1:4+ return on investment for pre-disaster resilience.

Communities often are asked to rely upon hydrological engineering and science as the holy grails in response to our floods, storms, hurricanes. And yet, there is a new "class" of data scientists, analytic tools, curated information, and significant user interfaces that have changed how government, industry, civic, academia and philanthropy can allocate their resources in more efficient and effective ways to unleash innovative resilience. Emerging enterprises and organizations to watch that are driving the "new resilience data science" for entrepreneurs and innovators alike to develop the next generation of insight include Jupiter Intelligence, HazardHub, ResilientGrid, and EcoMetrics.

What is rarely captured in the post-incident studies and gatherings is the powerful impact of the "GSD" networks — "The Get Shit Done" relationships, partnerships, tools and resources mobilized by unleashing innovation! And the good news is that Greater Houston as well as across the nation, a number of companies, products, integrated data-equipment, digital platforms, and best practices have emerged from several innovation ecosystems that should be brought to the forefront of any next steps for community and civic leaders seeking to address a 21st century resilience agenda.

There are the data and platform folks — Umanity, FoodBot, GotSpot, Crowd Source Rescue (all based in Houston) along with Harbor, R3Water, and a host of other national firms — for example that have addressed the speed by which needs, resources, information and actionable intelligence can align to assist volunteers, neighborhoods, philanthropy, and small businesses. As previous senior leadership of FEMA have admitted, the public sector can no longer be the go-to resource during every disaster, incident, and threat.If we are to democratize resilience because no one entity can afford continued losses — such as the insurance and reinsurance sector — nor is there enough taxpayer dollars to fix our critical infrastructure, then we must spark private-philanthropic-public partnerships through innovation.

If COVID -19 taught us anything, it's that we continue to face inventory management supply-chain, and resilient inventory problems that have been identified during and after previous disasters. With blockchain, advanced sensors and monitors, robotics and remote screening, reopening Greater Houston and the US can be done with innovative health technologies such as San Antonio-based Xenex.

In regards to the challenge before us, we must recall that the demand and intersection for an energy, water and data "nexus" began to take off in response to the Texas and California droughts, rose again to the forefront during multiple hurricanes in the US, and are a now the latest critical infrastructure focus in the post snowstorms of 2021.

Why is having Elon Musk's GigaFactory in Texas so vital to resilience innovation? Because the research and product development of batteries to retain solar and wind produced power can directly impact the load-demands in advance of an oncoming weather or worse a cybersecurity threat to the grid. Sunnova — another Houston brand — has been proving the benefit of storage capacity from its work in Puerto Rico and now exhibits the unique performance for future off-grid resilience of homes, medical offices, and vital services.

Until and unless the public sector opens the doors for these and other innovators through immediate and permanent changes in procurement and contracting, strategic partnerships, incentives and credits — while frankly sharing the leadership function with entrepreneurs, inventors, and investors — we will all pay the price for the failure to act.

There is still work to be done from a legislative and governmental perspective, but more and more innovators — especially in Houston — are proving to be essential in creating a better future for the next historic disaster we will face. The Insurance Information Institute's National Resilience Accelerator Initiative and Resilience Innovation Hub Collaboratory (with its flagship in Houston) is working to unleash the best of Texas', the Nation's and the World's best ideas, resources, information and investments.

------

Richard Seline is the co-founder of the Houston-based Resilience Innovation Hub.

Ad Placement 300x100
Ad Placement 300x600

CultureMap Emails are Awesome

Pharma giant considers Houston for $1B manufacturing campus

in the works

Another pharmaceutical giant is considering Houston’s Generation Park for a manufacturing hub.

According to a recent filing with the Texas Jobs, Energy, Technology and Innovation (JETI) program, Bristol Myers Squibb Co. is considering the northeast Houston management district for a new $1 billion multi-modal pharmaceutical manufacturing campus.

If approved, the campus, known as Project Argonaut, could create 489 jobs in Texas by 2031. Jobs would include operations technicians, engineering roles, administrative and management roles, production specialists, maintenance support, and quality control/assurance. The company predicts annual average wages for these positions to be around $96,000, according to the filing.

The project currently includes the 600,000-square-foot facility, but according to the filing, Bristol Myers Squibb “envisions this site growing in scale and capability well beyond its opening configuration."

The Texas JETI program offers companies temporary school property tax limitations in exchange for major capital investment and job creation. E.R. Squibb & Sons LLC applied for a 10-year tax abatement agreement in the Sheldon Independent School District.

The agreement promises a $ 1 billion investment. Construction would begin in 2027 and wrap in 2029.

“The proposed project reflects [Bristol Myers Squibb Co.’s] enduring commitment to bringing innovative medicines to patients and ensuring the long-term supply reliability they depend on,” the filing says. “The proposed project is purpose-built to support and manufacture medicines spanning multiple therapeutic areas and modalities, positioning the site as a long-term launch and commercial campus for decades to come. These medicines will provide therapies to the [Bristol Myers Squibb Co.’s] patients located in markets both nationally and internationally.”

The Fortune 100 company is considering 16 other cities for the new manufacturing facility in the Central and Eastern markets in the U.S. According to the Houston Chronicle, Bristol Myers Squibb Co is still in the “evaluation process” for its potential manufacturing site.

Last fall, Eli Lilly and Co. selected Generation Park for its $6.5 billion manufacturing plant. More than 300 locations in the U.S. competed for the factory. Read more here.

Houston health tech co. lands NIH grant for AI cancer prediction tool

fresh funding

Houston-based CellChorus and Stanford Medicine were recently awarded a Phase I Small Business Innovation Research grant for the company's AI platform to test how certain cancer patients will respond to therapies.

The funding comes from the National Cancer Institute of the National Institutes of Health. According to a filing, the grant totaled just under $400,000.

CellChorus, which spun out from the University of Houston’s Technology Bridge, has developed TIMING (Time-lapse Imaging Microscopy In Nanowell Grids), which analyzes the behavior of thousands of individual immune cells over time and can identify early indicators of treatment success or failure.

The company will work with Stanford's Dr. David Miklos and Dr. Saurabh Dahiya, who have built the Bone Marrow Transplantation and Cell Therapy Biobank. The biobank manages and stores biological samples from patients treated at their clinic and in clinical trials.

"Predicting which patients will achieve durable responses after CAR-T therapy remains one of the most important challenges in the field,” Miklos said in a news release. “We aim to uncover functional cellular signatures that can guide treatment decisions and improve patient outcomes.”

The project will specifically profile cells from patients with relapsed/refractory large B-cell lymphoma (r/rLBCL). According to CellChorus, only about half of r/rLBCL patients who receive CAR-T therapy "achieve a durable, long-term remission." Others do not respond to therapy or experience relapse.

“The sooner we know whether a cancer therapy is working, the better. To maximize patient benefit, we need technology that can provide a robust and early prediction of response to therapy. The technology needs to be scalable, cost-efficient, and capable of rapid turnaround times,” Rebecca Berdeaux, chief scientific officer of CellChorus, added in the release. “We are excited to work with Drs. David Miklos and Saurabh Dahiya and their colleagues on this very important project.”

CellChorus has previously received SBIR grants from federal agencies, including a $2.5 million award in 2024 from its National Center for Advancing Translational Sciences (NCATS) and a $2.3 million SBIR Fast-Track award from the National Institute of General Medical Sciences in 2023.

Houston museum showcases America's founding documents in rare exhibit

Experience History

As the United States prepares to celebrate its 250th birthday, Houstonians have a chance to see rare documents from the founding of the nation. Freedom Plane National Tour: Documents That Forged a Nation, presented by the National Archives Foundation, will be on display at the Houston Museum of Natural Science through Monday, May 25.

The collection includes a rare engraving of the original Declaration of Independence; official Oaths of Allegiance signed by George Washington, Aaron Burr, and Alexander Hamilton; a draft of the Bill of Rights; the Treaty of Paris, the documented that recognized America's independence from Great Britain; and the tally of votes approving the Constitution.

The National Archives specifically chose Houston as one of only eight cities in the country to host the exhibit as a means to help the documents reach a wider audience outside of the main hub of semiquincentennial events in New England and the Washington, D.C. area.

"One of the things we decided when we put the tour together because we wanted to be off the East Coast," said Patrick Madden, CEO of the National Archives Foundation, who was onsite for the exhibit's opening in Houston. "There's a lot of 250th celebration stuff happening in the original 13 colonies. How do we get it to major markets where larger numbers of people can see it? So in the case of Houston, obviously, [is a] major market in this part of the country, but also we've partnered with the museum twice before with National Archives exhibits, so we knew that they would be up to the task of handling the exhibit and the crowds."

The star of the collection is a rare engraving of the original Declaration of Independence. Secretary of State and future president John Quincy Adams commissioned 200 exact replicas of the document from engraver William J. Stone in 1823. Less than 50 now remain. Madden joyfully pointed out that there are errors in this document, a potent reminder that the men who forged a nation made mistakes.

"There's a couple of typos in it where they had to make corrections," said Madden. "So even the founders, you know, they're all human. That resonates because here these people are making this move against the most powerful nation in the world and putting their lives on the line for a country based on ideas."

Other impressive parts of the collection include official Oaths of Allegiance signed by George Washington, Aaron Burr, and Alexander Hamilton, as well as one of the drafts of the Bill of Rights. Many states would not ratify the Constitution until certain rights were included in the document, leading to Washington going on a national tour assuring state leaders enshrining protections was first on the list. The draft copy on display specifically shows the First Amendment in progress.

Houston is the fourth stop on the exhibition's tour, which will take the documents to Denver, Miami, Dearborn, and Seattle through the summer. Freedom Plane is just one part of a larger patriotic celebration at the HMNS, which includes a film series celebrating American science and culture and general Americana decoration throughout the main hall.

Admission to Freedom Plane is free to the public, but separate from general admission to the museum. Space is limited, and passes are available on a first-come, first-serve basis. Non-members should expect long waits or the possibility that the day's passes are sold out. Only museum members can reserve passes for specific times. Flash photography is prohibited due to the fragile nature of the documents.

---

This article originally appeared on CultureMap.com.