A Houston expert weighs in on the importance of breaking down barriers for innovation. Photo via Getty Images

Innovation has always been the driving force behind progress and development in every industry. It is the engine that propels growth, fosters competition, and improves people’s lives. The importance of innovation in every sector has grown exponentially in recent years with new ideas and technologies emerging faster than ever before. This explosion has led to innovation silos, where each industry is developing its own innovations and making progress in isolation from the others.

Houston has embraced the rise of innovation with gusto and is a prime city to break down industry specific silos. We proudly host the largest medical center and the energy capital of the world as well as the headquarters for the space race. The mayor’s office has shown a strong commitment to support rapid innovation growth, providing incentives and infrastructure for technology companies and talent to reside in Houston. Our city’s emerging innovation district has already shown huge promise with the Ion building and Greentown Labs providing a strong foundation to expand. Organizations uniting innovators across all industries like Pumps & Pipes could only exist in a city as diverse and accessible as Houston. Nonetheless, our community needs to band together to ensure innovation growth is inclusive of all industries to create an equitable approach to technology that will continue to benefit generations to come.

While innovation silos may have some benefits, such as competition and differentiation, they also have some significant drawbacks, including inefficiencies, redundancies, and missed opportunities. Industries can become so focused on their own innovations that they fail to see the potential for cross-industry collaboration. Many examples exist today where certain technologies or practices were once reserved for specific use cases and now have become mainstream. For instance, the use of the common GPS network for location and navigation services was originally pioneered by NASA, and hospital safety and quality checklists were derived from the airline industry. By soliciting more opportunities for innovation sharing, we can achieve faster growth, implement stronger and safer processes, and reduce repetitive and costly pilot testing in every industry from energy, health care, finance, social impact, and more.

I am putting out a call to action to the Houston community to open your doors to cross-industry partnerships.

Engage in more open dialogue and information sharing outside your industry.

Attend events that bring together professionals from all industries for knowledge sharing and idea exchange. Many conferences, workshops, and meet-ups already exist to unite and recognize cross-industry communities within specific interest groups. In addition, startup accelerators, incubator programs, and collaborative workspaces provide unique environments that encourage spontaneous conversations and positive idea exchange.

Incentivize businesses, start-ups, and individuals who are willing to collaborate and share their ideas with others.

Knowledge sharing should be rewarded through recognition programs, awards, special partnership opportunities, and more. Professional organizations and leadership networks are a great place to turn to for connecting with like-minded individuals and identifying recognition opportunities that can promote the great work of experience sharing.

Commit investments in cross-industry research and development.

We need to create more incentives for researchers to work across different industries and apply their expertise to various fields. Examples like the Ion Prototyping Lab, a one-of-a-kind makerspace for all, and events at the upcoming Ion Activation Festival, including “Back to the Future of Innovation”, unite researchers with industry to encourage collaborative collisions.

In the end, breaking down innovation barriers is essential if we want to continue on this upward, fast-growth trend to improve our community and to make an impact in people’s lives across the world. We need to take action now to promote a more seamless cross-industry approach to knowledge sharing, collaboration, and research and development to create a better future for all.

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Arielle Rogg is the principal and founder of Rogg Enterprises LLC, a Houston-based company providing digital marketing for health care innovators.

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Texas tops ranking of best state for investors in new report

by the numbers

Texas ranks third on a new list of the best states for investors and startups.

Investment platform BrokerChooser weighed five factors to come up with its ranking:

  • 2024 Google search volume for terms related to investing
  • Number of investors
  • Number of businesses receiving investments in 2024
  • Total amount of capital invested in businesses in 2024
  • Percentage change in amount of investment from 2019 to 2024

Based on those figures, provided mostly by Crunchbase, Texas sits at No. 3 on the list, behind No. 1 California and No. 2 New York.

Especially noteworthy for Texas is its investment total for 2024: more than $164.5 billion. From 2019 to 2024, the state saw a 440 percent jump in business investments, according to BrokerChooser. The same percentages are 204 percent for California and 396 percent for New York.

“There is definitely development and diversification in the American investment landscape, with impressive growth in areas that used to fly under the radar,” says Adam Nasli, head analyst at BrokerChooser.

According to Crunchbase, funding for Texas startups is off to a strong start in 2025. In the first three months of this year, venture capital investors poured nearly $2.9 billion into Lone Star State companies, Crunchbase data shows. Crunchbase attributes that healthy dollar amount to “enthusiasm around cybersecurity, defense tech, robotics, and de-extincting mammoths.”

During the first quarter of this year, roughly two-thirds of VC funding in Texas went to just five companies, says Crunchbase. Those companies are Austin-based Apptronik, Austin-based Colossal Biosciences, Dallas-based Island, Austin-based NinjaOne, and Austin-based Saronic.

Autonomous truck company rolls out driverless Houston-Dallas route

up and running

Houston is helping drive the evolution of self-driving freight trucks.

In October, Aurora opened a more than 90,000-square-foot terminal at a Fallbrook Drive logistics hub in northwest Houston to support the launch of its first “lane” for driverless trucks—a Houston-to-Dallas route on the Interstate 45 corridor. Aurora opened its Dallas-area terminal in April and the company began regular driverless customer deliveries between the two Texas cities on April 27.

Close to half of all truck freight in Texas moves along I-45 between Houston and Dallas.

“Now, we are the first company to successfully and safely operate a commercial driverless trucking service on public roads. Riding in the back seat for our inaugural trip was an honor of a lifetime – the Aurora Driver performed perfectly and it’s a moment I’ll never forget,” Chris Urmson, CEO and co-founder of Pittsburgh-based Aurora, said in a news release.

Aurora produces software that controls autonomous vehicles and is known for its flagship product, the Aurora Driver. The software is installed in Volvo and Paccar trucks, the latter of which includes brands like Kenworth and Peterbilt.

Aurora previously hauled more than 75 loads per week under the supervision of vehicle operators from Houston to Dallas and Fort Worth to El Paso for customers in its pilot project, including FedEx, Uber Freight and Werner. To date, it has completed over 1,200 miles without a driver.

The company launched its new Houston to Dallas route with customers Uber Freight and Hirschbach Motor Lines, which ran supervised commercial pilots with Aurora.

“Transforming an old school industry like trucking is never easy, but we can’t ignore the safety and efficiency benefits this technology can deliver. Autonomous trucks aren’t just going to help grow our business – they’re also going to give our drivers better lives by handling the lengthier and less desirable routes,” Richard Stocking, CEO of Hirschbach Motor Lines, added in the statement.

The company plans to expand its service to El Paso and Phoenix by the end of 2025.

“These new, autonomous semis on the I-45 corridor will efficiently move products, create jobs, and help make our roadways safer,” Gov. Greg Abbott added in the release. “Texas offers businesses the freedom to succeed, and the Aurora Driver will further spur economic growth and job creation in Texas. Together through innovation, we will build a stronger, more prosperous Texas for generations.”

In July, Aurora said it raised $820 million in capital to fuel its growth—growth that’s being accompanied by scrutiny.

In light of recent controversies surrounding self-driving vehicles, the International Brotherhood of Teamsters, whose union members include over-the-road truckers, recently sent a letter to Lt. Gov. Dan Patrick calling for a ban on autonomous vehicles in Texas.

“The Teamsters believe that a human operator is needed in every vehicle—and that goes beyond partisan politics,” the letter states. “State legislators have a solemn duty in this matter to keep dangerous autonomous vehicles off our streets and keep Texans safe. Autonomous vehicles are not ready for prime time, and we urge you to act before someone in our community gets killed.”

Houston cell therapy company launches second-phase clinical trial

fighting cancer

A Houston cell therapy company has dosed its first patient in a Phase 2 clinical trial. March Biosciences is testing the efficacy of MB-105, a CD5-targeted CAR-T cell therapy for patients with relapsed or refractory CD5-positive T-cell lymphoma.

Last year, InnovationMap reported that March Biosciences had closed its series A with a $28.4 million raise. Now, the company, co-founded by Sarah Hein, Max Mamonkin and Malcolm Brenner, is ready to enroll a total of 46 patients in its study of people with difficult-to-treat cancer.

The trial will be conducted at cancer centers around the United States, but the first dose took place locally, at The University of Texas MD Anderson Cancer Center. Dr. Swaminathan P. Iyer, a professor in the department of lymphoma/myeloma at MD Anderson, is leading the trial.

“This represents a significant milestone in advancing MB-105 as a potential treatment option for patients with T-cell lymphoma who currently face extremely limited therapeutic choices,” Hein, who serves as CEO, says. “CAR-T therapies have revolutionized the treatment of B-cell lymphomas and leukemias but have not successfully addressed the rarer T-cell lymphomas and leukemias. We are optimistic that this larger trial will further validate MB-105's potential to address the critical unmet needs of these patients and look forward to reporting our first clinical readouts.”

The Phase 1 trial showed promise for MB-105 in terms of both safety and efficacy. That means that potentially concerning side effects, including neurological events and cytokine release above grade 3, were not observed. Those results were published last year, noting lasting remissions.

In January 2025, MB-105 won an orphan drug designation from the FDA. That results in seven years of market exclusivity if the drug is approved, as well as development incentives along the way.

The trial is enrolling its single-arm, two-stage study on ClinicalTrials.gov. For patients with stubborn blood cancers, the drug is providing new hope.