Georgina Campbell Flatter worked closely with Greentown Labs when it was founded in 2011 and now will lead the incubator as CEO. Photo courtesy Greentown Labs

Houston and Boston climate tech incubator Greentown Labs has named Georgina Campbell Flatter as the organization’s incoming CEO.

Flatter will transition to Greentown from her role as co-founder and executive director of TomorrowNow.org, a global nonprofit that studies and connects next-generation weather and climate technologies with communities most affected by climate change.

“We are at a transformational moment in the energy transition, with an unprecedented opportunity to drive solutions in energy production, sustainability, and climate resilience,” Flatter said in a news release. “Greentown Labs is, and has always been, a home for entrepreneurs and a powerhouse of collaboration and innovation.”

Previously, Flatter worked to launch TomorrowNow out of tomorrow.io, a Boston-based AI-powered weather intelligence and satellite technology company. The organization secured millions in climate philanthropy from partners, including the Gates Foundation, which helped deliver cutting-edge climate solutions to millions of African farmers weekly.

Flatter also spent 10 years at the Massachusetts Institute of Technology (MIT), where she was a senior lecturer and led global initiatives at the intersection of technology and social impact. Her research work includes time at Langer Lab and Sun Catalytix, an MIT – ARPA-E-funded spin-out that focused on energy storage solutions inspired by natural photosynthesis. Flatter is also an Acumen Rockefeller Global Food Systems Fellow and was closely involved with Greentown Labs when it was founded in Boston in 2011, according to the release.

“It’s rare to find an individual who has impressive climate and energy expertise along with nonprofit and entrepreneurial leadership—we’re fortunate Georgie brings all of this and more to Greentown Labs,” Bobby Tudor, Greentown Labs Board Chair and Chairman of the Houston Energy Transition Initiative, said in a news release.

Flatter will collaborate with Kevin Dutt, Greentown’s Interim CEO, and also continue to serve on Greentown’s Board of Directors, which was recently announced in December and contributed to a successful $4 million funding round. She’s also slated to speak at CERAWeek next month.

“In this next chapter, I’m excited to build on our entrepreneurial roots and the strength of our ever-growing communities in Boston and Houston,” Flatter added in a news release. “Together, we will unite entrepreneurs, partners, and resources to tackle frontier challenges and scale breakthrough technologies.”

Greentown also named Naheed Malik its new chief financial officer last month. The announcements come after Greentown’s former CEO and president, Kevin Knobloch, announced that he would step down in July 2024 after less than a year in the role.

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This article originally appeared on our sister site, EnergyCapital.

Greentown Houston is asking its current and potential members what they want in a wet lab. Photo via GreentownLabs.com

Greentown Houston announces plans for wet lab, calls for feedback from members

seeing green

Greentown Houston has announced it's building a new wet lab facility — but first, they need some help from the community.

Greentown Labs, which is dual located at their headquarters in Somerville, Massachusetts, and in the Ion District in Houston, has announced that they are building out a wet lab in their Midtown space.

"We have heard from several startups as well as corporate partners in the ecosystem that are looking for wet lab space," says Lara Cottingham, vice president of strategy, policy, and climate impact at Greentown Labs. "Greentown has experience running wet labs from our location in Somerville. We're excited to be able to offer wet lab space to climatetech startups as an additional amenity to the Ion District.

Although Greentown's Boston-area location has wet lab space, Cottingham says the organization is not interested in copying and pasting that same facility. Greentown wants to provide the tools that the Houston ecosystem needs, and that requires getting feedback from its current and potential members.

"We want to announce to the community that this is something we're going to build — but we still need a lot of feedback and input from startups so we can learn what exactly they need or want to see from the wet lab," Cottingham tells InnovationMap. "No two wet labs are the same."

Right now, there aren't any details available about timeline or specifics of the new facility. Greentown is prioritizing getting feedback from its members and having conversations with potential sponsors and corporate partners.

"Corporate partners are a big part of the ecosystem and the community at Greentown. They can be so many things to our startups — mentors, customers, investors," Cottingham says. "And in this space, they can help us sponsor and financially support the wet lab. We're still fundraising — we have some partners that have committed to funding, but we're still looking for more funding."

In addition to monetary contribution, Cottingham says they are looking for other options as well, from partnerships with equipment providers, hazardous materials management, and more.

Startups that need wet lab space are encouraged to fill out the online form, which will be open through the summer, and potential corporate partners can express their interest online as well.

Greentown Houston opened its doors in 2021 and has since grown to house more than 75 energy and climatetech startups, as well as several accelerators, thanks to support from dozens of corporate partners.

Anu Puvvada, KPMG Studio leader, shares how her team is advancing software solutions while navigating hype cycles and solving billion-dollar-problems. Photo courtesy of KPMG

How this Houston-based studio is tackling billion-dollar problems with internal innovation

Q&A

In 2021, KPMG, a New York-based global audit, accounting, and advisory service provider, formed a new entity to play in the innovation space. The Houston-based team finds innovative software that benefit KPMG's clients across industries.

"We're really focused on transformative businesses that we can offer our clients in the next three to five years to solve fairly large problems," Anu Puvvada, KPMG Studio leader, tells InnovationMap.

Now, almost two years later, KPMG Studio has spun out its first company, AI-based security startup Cranium, which has raised $7 million in a seed round led by SYN Ventures with support from KPMG.

Established to advance internal innovation, KPMG Studio's technologies don't always get spun out into startups like Cranium, but with support of the team, the early-stage ideas receive guidance from the company's resources with the potential to be rolled into KPMG's suite of services for its clients.

In an interview with InnovationMap, Puvvada shares more about the program, the Cranium spin out, and why she's passionate about leading this initiative from Houston.

InnovationMap: Tell me about KPMG Studio's structure and your overall goal with the program.

Anu Puvvada: I like to think about it more around framing. We frame the studio around three pillars: incubate, accelerate and amplify. We take in a lot of ideas that come from the business and from our clients and we incubate and see which of them are really high growth solving like a very large problem across verticals and horizontals. When I say a big problem — it's got to be a $1 billion-plus problem. With Cranium, we saw some very early indicators, like a rise in AI adoption amongst our clients. We saw that AI was in this spot where it was going to hit an exponential growth marker. We also saw a rise in cyber attacks. All of that plus conversations with clients made us realize that there's there's something big brewing here.

We're looking at a ton of ideas, and then parsing out maybe 10 that we create into the next Cranium. And then in accelerate, we're finding early adopters and we're growing the idea, building it, raising venture capital for the idea if we decide to spin it out.

IM: Seems like a mutually beneficial relationship between KPMG and these innovators, right?

AP: I would say it's good for KPMG because it allows us to innovate differently and innovate with agility. My group actually operates as a startup within a large organization. And then we create this ecosystem around startups inside KPMG, so when it exits, it's got the basis to run on its own. That's important for us because it gives us agility, it lets us really capitalize on our brand. It's not just what it brings us, but also what it brings our clients.

There's a big competitive advantage to innovating inside KPMG. These innovators get to work inside our walls protected by the infrastructure of KPMG. They, they get a technology team to help them build the idea. And they get to use their brand of KPMG, use our marketing engine, our comms engine, like everything that's behind us. A startup outside, it doesn't get any of that. So, it almost like accelerates them into market when the spin out happens. We use the differentiators and the competitive advantage of KPMG in order to amplify the story of that startup and their value proposition in the market.

IM: So there are two paths for these technologies, right?

AP: We either have what we call spin ins, which means it's created and spins into the business or we have spin outs, which is what Cranium is. We classify spin outs into its own startup or a sale of an asset. And then for the spin in, we would license to our clients under the mothership of KPMG.

IM: Is the studio operating completely in Houston?

AP: We source our ideas from all over nationally. I'm in Houston and a lot of my support team is actually in Houston as well. And I work with a lot of the Houston ecosystem around innovation. I really see Houston as a big future market. We are at the center of climate and ESG, the space economy, and medicine. Those are three big like curves that are going to be hitting in the next five years. So, it is integral for studio to be integrated into that ecosystem to position KPMG for the future.

IM: What's your vision for the studio?

AP: I definitely see us taking in more ideas into studio to build internally for our pioneers, which is what we call our innovators — Jonathan Dambrot, who is the founder of Cranium, he's the pioneer. We'll definitely be doing more Craniums that spin out of the firm. And we have a number that are spinning into the firm already.

I also see us evolving to bring in external startups into the studio so we can also give them the entire ecosystem a way to be lifted up and to shepherd each other into the future.

It's really important that anything that we invest in and we work on is staying measured through these hype cycles that are happening. We need to make sure that these ideas are grounded in the problem that's being solved in an adaptable way and that there's a strong market need for it. That's something that the studio really spends a lot of time doing in the beginning, which kind of helps mitigate some of these hype cycles for us and our clients.

When you think about innovation as a whole, it's mired with risk and uncertainty. You never know if something's going to work or not. And part of what we have to do with any idea that we're building in the studio or anything that our clients are doing around innovation, we have to do as much as we can to mitigate that risk and uncertainty. And that's kind of what KPMG's wheelhouse is.

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This conversation has been edited for brevity and clarity.

Emily Reichert, CEO of Greentown Labs, shares why the incubator's expansion was a year in the making — and only just the beginning. Photo courtesy of Greentown Labs

New-to-Houston startup incubator CEO on why there's 'no better place' to expand

Q&A

Greentown Labs announced its intent on expanding to Houston last week with 11 corporate partners signed on already, and is currently scouting out its physical location in town

Already, says Emily Reichert, CEO of Greentown Labs, the Bayou City has left a positive impression on her and her team.

"It's exciting to see how many people we can engage in being part of the future of energy," Reicher shares in an interview with InnovationMap. "I think there's really no better place for that to be led out of Houston."

Two Houstonians have been identified to lead local efforts. Jason Ethier, a Houston-based energy tech founder, is the operations lead for Greentown Houston, and Juliana Garaizar, local investor and former director of the TMC Venture Fund, is the Greentown Houston launch director.

Reichert, in the Q&A with InnovationMap, shares more on what her organization's Houston plans are, what she's looking for in participating startups, and when the city will know more about the brick-and-mortar space.

InnovationMap: When did Greentown Labs start considering a second location?

Emily Reichert: Greentown I think seriously began entertaining the idea of Houston as a possibility during the CERAWeek conference in March 2019. I was there to speak in a couple of their pods, and there were actually 10 Greentown teams there as well.

Jason Ethier of Dynamo Micropower, who was on our board and based in Houston, had been encouraging us to consider Houston for a long time because of the need for someone to be bringing together the community of entrepreneurs around cleantech in Houston. And he felt, talking to other entrepreneurs, that there was a bit of a gap there and that it would be beneficial to have a Greentown labs in Houston to convene that community. Up until that point, I had kind of said, "Jason, I can't think about that." We were expanding in Boston just a year earlier, and we had more than doubled in size. But for the first time in March 2019, it seems like something that we should at least entertain.

During that course of that visit, the Greater Houston Partnership, Jason, and I believe some folks from Houston Exponential as well, were involved in setting up a series of meetings for me to really test the idea of Greentown Labs coming to Houston.

So, I talked with a diversity of partners, city officials, and — probably most importantly from my perspective — a bunch of entrepreneurs that showed up with less than a week's notice at a bar in EaDo. They really expressed to me that they felt that need for a community for cleantech entrepreneurs. And that there really wasn't anything equivalent and that there was a gap there.

To me, that was really the trigger for turning this all on as a serious opportunity for Greentown. We're really all about entrepreneurs. Our mission is to support them and help them get their clean technology into the world where it can have an impact and make a difference. Knowing that there was an entrepreneur community that needed fostering and growing and building was really a reason for Greentown Labs to come to Houston.

IM: What about Houston was alluring for the organization?

ER: When people ask me, "Why Houston?" the first thing that I always say is it's the energy capital of the world, and we are an organization that is promoting the entrepreneurship of companies that are developing the world's next energy solutions. It makes total sense to be working in the place where the companies and customers are that are really putting these technologies into the marketplace. So, it being the energy capital of world is kind of a key driver — and one that we think needs to be the energy transition capital of the world, which is where we're all headed in needing to address climate change.

IM: I see several corporate partners have been announced — are you looking for more and what role do the corporates play in the incubator?

ER: The corporate partners are incredibly important to the entrepreneurs that Greentown Labs support. The reason for that is that most of the startups that we work with are going to be selling their solutions to a larger partner. They're not consumer oriented startups — they're going to be a B2B-type play. So, in order to get these solutions that the startups are building to scale, they need to partner with usually another large entity to help that happen.

From the get-go, corporate partners have been part of Greentown's overall community of solutions for startups to get their technology to scale. We work with about 50 corporate partners total.

I'd say there's a variety of ways that they participate — one is simply mentorship and expertise that they can provide the startup real market knowledge and know how. They can also provide investment or a place to do pilot studies, they can do licensing agreements, and they can be customers — that's another important role.

We are absolutely looking for more corporate partners because the energy transition is a big problem, and we're going to need lots of partners in the solution. We would invite others to reach out to us.

IM: How will Greentown Houston be different from the original in Massachusetts?

ER: We're starting at a more modest size than we are currently in Massachusetts. We're a 100,000-square-foot, three-building campus in Somerville just outside of Boston, and we can accommodate about 100 startups in that location.

In Houston, we're starting at the scale that we actually started at in 2013, and that is about a capacity for about 50 startups in about 30,000 square feet with about 120 desks and about 20,000 square feet of prototyping lab space. The space that we're building in Houston will be smaller, but also very flexible.

We don't quite know yet what the Houston market wants and needs, and so we have to just kind of plan to create a flexible structure based on what we know that Houston entrepreneurs need and then kind of evolve from there.

IM: You don't have office space pinned down yet — what are you looking for in an office and what's your timeline for announcing more details?


ER: I think we'll be able to announce that in September. But, I will say that we've been pleasantly surprised by the different opportunities that are available and how so many people just trying to help and provide us with space, but I'd say we are pretty much there on selecting the space.

We will be retrofitting an existing building, which is exactly what we did whenever we moved into Somerville in 2013. We like to preserve flexibility and, until we really understand the market, we don't want to custom build anything because what if we created it and then no one needed it?

Instead, we're going to take over an existing industrial-type building that can be utilized for our purpose. And for our purpose, we need a lot of electricity, we need cement floors that can take a lot of weight, and we need to kind of have some isolation in terms of the machine tools and whatnot that can make a lot of noise — so can our events.

IM: With two pairs of boots on the ground already, will you be growing your Houston team?

ER: It somewhat depends on the track of our fundraising, but currently the plan right now is to do some additional hiring in late 2020 or 2021 — at which time we'll probably be looking for a community manager, a lab manager, and a program manager. Those all won't happen at the very beginning, but the community manager is probably the next position we'd be hiring for. That role is just incredibly critical to doing what we do at Greentown Labs, which is bringing together that community of entrepreneurs, helping them connect with one another, and really just helping them to support one another as peers.

IM: What are you looking for in participating startups and how can Houston startups get involved and learn more?

ER: Absolutely. We would love it if Houston entrepreneurs want to reach out to us. We have a landing page specifically for Houston on our website, and that will allow you to actually fill out a form that allows us to follow up with you.

We will be starting to have early access membership that Houston entrepreneurs can take advantage of uniquely, and that will allow entrepreneurs to start getting engaged in what right now will probably be mainly virtual events, but going forward, it's a great way to start learning about the community and really for the community to be built before we have a physical location that can bring people in. More information out that will be coming out in the next couple of weeks.

In terms of what we're looking for, we are looking for startups that are actively working on climate or environmental solutions — especially those that are working on reducing greenhouse gas emissions through electricity, transportation, agricultural tech and water, building, manufacturing, or industry industrial applications. There's a lot of broad categories, but reducing greenhouse gas emissions is a big challenge and it needs to be attacked in all sectors of the economy.

Even beyond energy or renewable energy, there are a lot of different solutions that we consider as part of clean tech and climate tech. We're just really excited to learn about more entrepreneurs and engage with them as a part of building Greentown Labs Houston.

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This conversation has been edited for brevity and clarity.

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Rice launches 'brain economy' initiative at World Economic Forum

brain health

Rice University has launched an initiative that will position “brain capital” as a key asset in the 21st century.

Rice rolled out the Global Brain Economy Initiative on Jan. 21 at the World Economic Forum in Davos, Switzerland.

“This initiative positions brain capital, or brain health and brain skills, at the forefront of global economic development, particularly in the age of artificial intelligence,” the university said in a news release.

The Rice-based initiative, whose partners are the University of Texas Medical Branch in Galveston and the Davos Alzheimer’s Collaborative, aligns with a recent World Economic Forum and McKinsey Health Institute report titled “The Human Advantage: Stronger Brains in the Age of AI,” co-authored by Rice researcher Harris Eyre. Eyre is leading the initiative.

“With an aging population and the rapid transformation of work and society driven by AI, the urgency has never been greater to focus on brain health and build adaptable human skills—both to support people and communities and to ensure long-term economic stability,” says Amy Dittmar, a Rice provost and executive vice president for academic affairs.

This initiative works closely with the recently launched Rice Brain Institute.

In its first year, the initiative will establish a global brain research agenda, piloting brain economy strategies in certain regions, and introducing a framework to guide financial backers and leaders. It will also advocate for public policies tied to the brain economy.

The report from the McKinsey Health Institute and World Economic Forum estimates that advancements in brain health could generate $6.2 trillion in economic gains by 2050.

“Stronger brains build stronger societies,” Eyre says. “When we invest in brain health and brain skills, we contribute to long-term growth, resilience, and shared prosperity.”

Rice Alliance and the Ion leader Brad Burke to retire this summer

lasting legacy

Brad Burke—a Rice University associate vice president who leads the Ion District’s Rice Alliance for Technology and Entrepreneurship and is a prominent figure in Houston’s startup community—is retiring this summer after a 25-year career at the university.

Burke will remain at the Rice Alliance as an adviser until his retirement on June 30.

“Brad’s impact on Rice extends far beyond any single program or initiative. He grew the Rice Alliance from a promising campus initiative into one of the most respected university-based entrepreneurship platforms,” Rice President Reginald DesRoches said in a news release.

During Burke’s tenure, the Rice Business School went from unranked in entrepreneurship to The Princeton Review’s No. 1 graduate entrepreneurship program for the past seven years and a top 20 entrepreneurship program in U.S. News & World Report’s rankings for the past 14 years.

“Brad didn’t just build programs — he built an ecosystem, a culture, and a reputation for Rice that now resonates around the world,” said Peter Rodriguez, dean of the business school. “Through his vision and steady leadership, Rice became a place where founders are taken seriously, ideas are rigorously supported, and entrepreneurship is embedded in the fabric of the university.”

One of Burke’s notable achievements at Rice is the creation of the Rice Business Plan Competition. During his tenure, the competition has grown from nine student teams competing for $10,000 into the world’s largest intercollegiate competition for student-led startups. Today, the annual competition welcomes 42 student-led startups that vie for more than $1 million in prizes.

Away from Rice, Burke has played a key role in cultivating entrepreneurship in the energy sector: He helped establish the Energy Tech Venture Forum along with Houston Energy and Climate Startup Week.

Furthermore, Burke co-founded the Texas University Network for Innovation and Entrepreneurship in 2008 to bolster the entrepreneurship programs at every university in Texas. In 2016, the Rice Alliance assumed leadership of the Global Consortium of Entrepreneurship Centers.

In 2023, Burke received the Trailblazer Award at the 2023 Houston Innovation Awards and was recognized by the Deshpande Foundation for his contributions to innovation and entrepreneurship in higher education.

“Working with an amazing team to build the entrepreneurial ecosystem at Rice, in Houston, and beyond has been the privilege of my career,” Burke said in the release. “It has been extremely gratifying to hear entrepreneurs say our efforts changed their lives, while bringing new innovations to market. The organization is well-positioned to help drive exponential growth across startups, investors, and the entrepreneurial ecosystem.”

Starting April 15, John “JR” Reale Jr. will serve as interim associate vice president at Rice and executive director of the Rice Alliance. He is managing director of the alliance and co-founder of Station Houston, beginning April 15. Reale is co-founder of the Station Houston startup hub and a startup investor and was also recently named director for startups and investor engagement for the Ion.

“The Rice Alliance has always been about helping founders gain advantages to realize their visions,” Reale said. “Under Brad’s leadership, the Rice Alliance has become a globally recognized platform that is grounded in trust and drives transformational founder outcomes. My commitment is to honor what Brad has built and led while continuing to serve our team and community, deepen relationships and deliver impact.”

Burke joined the Houston Innovators Podcast back in 2022. Listen to the full interview here.

Houston team uses CPRIT funding to develop nanodrug for cancer immunotherapy

cancer research

With a relative five-year survival rate of 50 percent, pancreatic cancer is a diagnosis nobody wants. At 60 percent, the prognosis for lung cancer isn’t much rosier. That’s because both cancers contain regulatory B cells (Bregs), which block the body’s natural immunity, making it harder to fight the enemies within.

Newly popular immunotherapies in a category known as STING agonists may stimulate natural cancer defenses. However, they can also increase Bregs while simultaneously causing significant side effects. But Wei Gao, assistant professor of pharmacology at the University of Houston College of Pharmacy, may have a solution to that conundrum.

Gao and her team have developed Nano-273, a dual-function drug, packaged in an albumin-based particle, that boosts the immune system to help it better fight pancreatic and lung cancers. Gao’s lab recently received a $900,000 grant from the Cancer Prevention and Research Institute of Texas (CPRIT) to aid in fueling her research into the nanodrug.

“Nano-273 both activates STING and blocks PI3Kγ—a pathway that drives Breg expansion, while albumin nanoparticles help deliver the drug directly to immune cells, reducing unwanted side effects,” Gao said in a press release. “This approach reduces harmful Bregs while boosting immune cells that attack cancer, leading to stronger and more targeted anti-tumor responses.”

In studies using models of both pancreatic and lung cancers, Nano-273 has shown great promise with low toxicity. Its best results thus far have involved using the drug in combination with immunotherapy or chemotherapy.

With the CPRIT funds, Gao and her team will be able to charge closer to clinical use with a series of important steps. Those include continuing to test Nano-273 alongside other drugs, including immune checkpoint inhibitors. Safety studies will follow, but with future patients in mind, Gao will also work toward improving her drug’s production, making sure that it’s safe and high-quality every time, so that it is eventually ready for trials.

Gao added: “If successful, this project could lead to a new type of immunotherapy that offers lasting tumor control and improved survival for patients with pancreatic and lung cancers, two diseases that urgently need better treatments."