These Houston startups and companies clock in as the top employers in the U.S.

best of the rest

MD Anderson Cancer Center is a top place to work in the U.S. and Texas. Photo by F. Carter Smith/courtesy of MD Anderson

Whose boss is doing something right in Houston? Forbes set out to find out.

New rankings from Forbes identified the top employers in Houston and beyond, and that included both bigger companies and the country’s best startup employers. In Houston, the startups ranked as top employers are:

No. 120 — Imbuit
No. 310 — Code Ninjas (Pearland)
No. 353 — Axiom Space
No. 462 — Liongard

When it comes to more traditional businesses, Dr. Pete Pisters, CEO of MD Anderson Cancer Center, continues his reign. He was named a top boss in 2021. Now, the cancer treatment facility/research center he leads has been named one of the best employers in a new report.

MD Anderson Cancer Center ranked No. 10 among the country’s best large employers in the country. Staffing some 22,000 employees, the world-renowned cancer center also landed at No. 25 in Forbes list of America's Best Employers in 2021.

Other Houston-area companies on the list include: Houston Methodist (No. 37), Waste Management (No. 245), Sysco (No. 314), Shell Oil (no. 361), Halliburton (No. 389), Schlumberger (No. 403), ExxonMobil (No. 440), and BP (No. 487).

Other Texas employers ranked among the best large employers in the U.S. are:

  • No. 10 — MD Anderson Cancer Center, Houston
  • No. 37 — Houston Methodist, Houston
  • No. 38 — H-E-B, San Antonio
  • No. 135 — USAA, San Antonio
  • No. 140 — Keller Williams Realty, Austin
  • No. 143 — Dell Technologies, Round Rock
  • No. 214 — Texas Tech University, Lubbock
  • No. 245 — Waste Management, Houston
  • No. 279 — University of Texas at Austin
  • No. 314 — Sysco, Houston
  • No. 318 — Daikin Industries, Waller (North American operations hub for manufacturing, marketing, research, R&D, and customer support)
  • No. 324 — Whole Foods Market, Austin
  • No. 361 — Shell Oil, Houston
  • No. 389 — Halliburton, Houston
  • No. 403 — Schlumberger, Houston
  • No. 440 — ExxonMobil, Houston
  • No. 487 — BP, Houston (North American headquarters)

Elsewhere in Texas, Dallas reigns as the capital of Texas when it comes to the best big and small employers, according to Forbes, which put University of Texas Southwestern Medical Center in Dallas at No. 9 among the country’s best large employers in the country and Dallas-based life insurance platform Bestow at No. 16 among the country’s best startup employers.

UT Southwestern isn’t the only Dallas-Fort Worth employer to pop up on the Forbes list of the best large employers. Richardson-based software company RealPage sits at No. 49; Dallas-based Southwest Airlines, No. 56; Plano-based Toyota North America, No. 253; Plano-based Cinemark, No. 370; Dallas-based Jacobs, No. 375; Dallas-based Topgolf, No. 394; Dallas-based Primoris Services, No. 399; Irving-based Fluor, No. 422; Dallas-based CBRE, No. 423; Irving-based McKesson, No. 429; Fort Worth-based American Airlines, No. 446; and Plano-based Keurig Dr Pepper, No. 483.

Dallas-based software company Slync.io, holding the No. 290 spot for best startups.

What follows are the other Texas employers ranked among the best startup employers in the country.

Austin

No. 104 — Apty
No. 121 — Homeward
No. 169 — SparkCognition
No. 186 — Outdoor Voices
No. 255 — Outdoorsy
No. 323 — ICON
No. 324 — The Zebra
No. 330 — TrustRadius
No. 335 — Innovetive Petcare (Cedar Park)
No. 387 — AlertMedia
No. 400 — Iris Telehealth
No. 410 — Wheel
No. 455 — Billd
No. 460 — Aceable
No. 470 — Shipwell

Forbes teamed up with data and research company Statista to develop the rankings of the best large employers and best startup employers.

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Houston college joins inaugural workforce accelerator supported by Google

hands-on training

Houston City College (HCC) is one of 15 community colleges from around the country to be selected for the first-ever Workforce Futures Accelerator.

The three-year effort is supported by Google.org, the tech company’s philanthropic arm, and led by the Association of Community College Trustees (ACCT), a non-profit educational organization that represents over 500 community, junior, and technical colleges. The accelerator focuses on helping colleges embed virtual, employer-sponsored training opportunities into short-term workforce training programs, giving participants access to opportunities that they might otherwise receive through internships or other "work-based learning" stints.

"The Workforce Futures Accelerator reflects the Houston City College mission of offering a high-quality, affordable education for workforce training and career development," Pretta VanDible Stallworth, HCC trustee and chair-elect of the ACCT board of directors, said in a news release. "Advancing student success and creating pathways to opportunities ensures that our students are well equipped to succeed and build a secure future in today's economy.”

Through the accelerator, HCC is tasked with fusing online project-based learning opportunities with its workforce education programs. The idea is to give students hands-on experiences working on projects sponsored by employers, allowing them to gain real-world knowledge in the process.

HCC will select two workforce programs that meet the accelerator’s criteria and insert into them into coursework. In the second and third year of the accelerator, the selected colleges are expected to scale the programs by adding instructors and programs to develop a network of to support their continued implementation.

“Participation by HCC will strengthen how we provide students with career-connected learning experiences that complement their classroom education and align with the needs of employers,” HCC Chancellor Margaret Ford Fisher added in the news release. “We are focused on ‘future forward’ strategies to meet the present and future needs of our region’s businesses.”

Two other Texas colleges were chosen to participate in the accelerator: Lamar Institute of Technology in Beaumont and Grayson College in Denison.

The remaining cohort includes:

  • Bergen Community College in Paramus, New Jersey
  • Central Louisiana Community College in Alexandria, Louisiana
  • Clark State College in Springfield, Ohio
  • Great Basin College in Elko, Nevada
  • Heartland Community College in Normal, Illinois
  • Hudson County Community College in Jersey City, New Jersey
  • Manchester Community College in Manchester, New Hampshire
  • Mesa Community College in Mesa, Arizona
  • Mohave College in Kingman, Arizona
  • San Joaquin Delta Community College in Stockton, California
  • San Juan College in Farmington, New Mexico
  • West Virginia University Parkersburg in Parkersburg, West Virginia

New report ranks Texas among top 10 states where AI could disrupt jobs

AI Workforce

A new nationwide report examining where AI could "reshape" the most jobs has ranked Texas No. 9 among the most at-risk states for AI job disruption.

The new SmartAsset report compared all 50 states and the District of Columbia to calculate the estimated percent of the workforce employed in the 26 occupations with the highest AI exposure, as determined by June 2026 research by the Virginia Economic Information and Analytics Division.

The findings revealed that 500,000 Texas workers, or 3.55 percent of the total workforce, are employed in occupations with "high exposure to potential AI disruption."

This also places the Lone Star State as the 9th most at-risk state in the U.S. where AI exposure can lead to "declining hiring demand, wage pressure, task automation, and other forms of disruption."

"States with larger concentrations of highly exposed occupations could experience more pronounced labor-market changes, particularly in roles where core tasks are more vulnerable to AI-driven restructuring," the report's author wrote.

Texas' biggest cities, like Houston and Austin, are known for their thriving tech and business industries, and the study noted that many of the occupations within those sectors are the most at risk. The Virginia Economic Information and Analytics Division said the top five most AI-exposed occupations in the U.S. are: mathematicians, proofreaders, correspondence clerks, court reporters, and media and communication workers. Additionally, computer programmers, database administrators, web developers, telephone operators, and communications equipment operators round out the top 10 most at-risk positions.

These are the 16 remaining occupations most exposed to AI disruption, in order:

  • Data Entry Keyers
  • Statistical Assistants
  • Office Support Workers
  • Interpreters and Translators
  • Database Architects
  • Software Quality Assurance Analysts
  • Medical Transcriptionists
  • Software Developers
  • Writers and Authors
  • Payroll Clerks
  • Web Designers
  • Miscellaneous Computer Occupations
  • Insurance Claims Processors
  • Telemarketers
  • Computer Numerically Controlled Tool Programmers
  • Bookkeeping and Accounting Clerks

A separate SmartAsset report from April 2026 found about 20.5 percent of Texas workers use AI to do their jobs in some capacity. That trend will continue to shift further as employers and employees choose to adopt — or reject — AI implementation.

Across the U.S., Washington topped the list as the state with the highest concentration of AI-exposed jobs, with nearly 5.7 percent of the state's workforce employed in the 26 most at-risk positions. SmartAsset said Washington's high prevalence of technology companies is a significant factor that skyrocketed the state to the top of the list.

"Home to major technology companies including Microsoft, Amazon, T-Mobile and Expedia, the state has large numbers of computer programmers and software developers, two occupations with high exposure," the report said.

Meanwhile, Mississippi ranked No. 51 with the lowest concentration of AI-exposed jobs in the nation. About 22,500 workers in Mississippi, or 1.93 percent of its workforce, are at risk for AI disruption.

The top 10 states where AI could reshape the most jobs are:

  • No. 1 – Washington
  • No. 2 – Virginia
  • No. 3 – District of Columbia
  • No. 4 – California
  • No. 5 – Utah
  • No. 6 – Maryland
  • No. 7 – Colorado
  • No. 8 – New Hampshire
  • No. 9 – Texas
  • No. 10 – North Carolina
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This article originally appeared on CultureMap.com.

UH lands $1.2M NIH grant to fight superbugs using AI, quantum sensing

drug defense

The fight against antibiotic-resistant bacteria like MRSA is getting science fiction-like upgrades at the University of Houston thanks to a new four-year, $1.26 million grant from the National Institutes of Health.

The university says the recent funding brings total federal support up to $3.5 million for 11 years for the project, which uses AI and quantum-sensing technology to better understand how bacterial proteins develop resistance to drugs.

Any medical professional will tell you that one of the worst things that can happen is almost killing an infection. Bacteria that survive attacks from conventional antibiotic treatments emerge tougher, more resistant and more aggressive than before–making them much harder to treat. A good example is the superbug methicillin-resistant Staphylococcus aureus (MRSA).

UH chemistry professors Yuhong Wang and Shoujun Xu are working on this issue. They know full well that fighting superbugs requires new technology and new approaches, which is what they aim to pioneer with their new grant.

“Drug-resistant bacterial infections such as MRSA are becoming harder to treat, creating an urgent need for faster ways to understand how antibiotics and other small molecules interact with bacterial proteins,” Wang said in a news release.

Wang and Xu’s work centers around GTP, a cellular fuel that can cause tiny changes to a cell's structure when it mutates. Sometimes, those shape changes make it easier for drugs to breach the wall and attack the cells.

The UH scientists are employing AlphaFold, an AI-powered tool that can scan large molecular libraries in seconds. From these models, they can see promising drug combinations for future testing.

Once identified, the team uses their invention, super-resolution force spectroscopy, to monitor the cells. Tiny magnetic beads are attached to genetic material, then magnified to see how strong that material is when pulled. They can measure this incredible microscopic process through an atomic magnetometer, typically used in quantum physics. Combined, all these tools allow a high-definition look at how each molecule might respond to new chemical approaches.

“We're the only chemists in the world that use an atomic magnetometer for biological research,” Xu said. “It's a technique developed by physicists, and there is usually a gap between techniques developed by physicists and biological applications. Yuhong and I have been bridging that gap together for the past 10 years.”

Eventually, Wang and Xu hope to develop powerful software that can be used by drug manufacturers to model cellular responses. With enough predictive data, the software could even get ahead of superbugs’ own mutation, allowing drugs to be developed before new strains arrive.

"We want an algorithm where you input a protein sequence, score the mutation hotspots, and develop new inhibitors before a drug-resistant species even emerges," Wang added.

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