The YMCA of Greater Houston has launched a virtual platform called HTX+. Image via HTXplus.org

It started with a Zoom class. Shelby Saylor remembers shutting the doors to the YMCA of Greater Houston on March 17, 2020, as the threat of the coronavirus pandemic surged across the city. Like the rest of the world, the executive director of healthy living had no idea when the YMCA would reopen to its community.

"How do we reach our friends and our community in a time where they are isolated and maybe a little lost?" asked Saylor.

Using a webcam, the staff at YMCA of Greater Houston began recording videos and supportive content for members within the early days of the pandemic.

"We were more concerned with getting a product out there because it was needed, and then we iterated for quality," she says.

Over time, the concept of digital programming evolved into HTX+, the YMCA of Greater Houston's new on-demand virtual platform with fitness and wellness courses and resources for all ages.

The platform has emerged at a time when digital resources have become a necessity for people to work and live. The YMCA has been a long-held bastion of community outreach, making its resources accessible to all and working to eradicate inequalities. The virtual service emerged as a solution for addressing food insecurity, racial inequities, health disparities, social isolation, and learning gaps from afar.

"It was a two-pronged process," explains Shelby. "We had to serve the immediate needs...so we looked at the gaps in our communities as well as the gaps from closing out brick-and-mortar for a period of time," she says.

From there, the YMCA answered another question: "What gaps can we fill once we are at 100 percent capacity?"

"People are going to come back at different levels," says Saylor. She describes her own uneasiness going into a crowded grocery store and feeling her heart race. "It's going to take some time [for people] to unlearn some of that social isolation," she anticipates.

HTX+ includes fitness, mindfulness, virtual personal training, and educational resources members can access from anywhere. Saylor feels the platform, available on the Houston YMCA app and online, will help enhance the Y experience even after the pandemic. She notes the interactive platform can supplement members' in-person workouts and also provide the connection to those who are not yet comfortable returning to the facility.

"It has tremendously grown with webinars where you can ask questions and be a part of more than just the content that we're all used to consuming right now," she says.

One offering that has helped members at the YMCA handle the onslaught of pandemic stress is meditations. Saylor, who says she typically prefers to be behind the camera, was proud to step out of her comfort zone to teach a midday meditation.

Programs targeted to different age groups, from children to seniors, have helped provide resources and tools to two generations with unique needs.

"I'm really proud of our ability to find stuff for younger members because there is just not that much out there," she says. The HTX Kids program has evolved to include STEM activities, sports, crafts, and learning. "Seeing all come to fruition from one Zoom video to where it is now—I couldn't be more proud," she continued.

YMCA Virtual Personal Trainingwww.youtube.com

ForeverWell, a program for members ages 55 and up, has also expanded digital opportunities to members.

"We focus on things that maybe younger communities don't have to tackle beyond your social isolation but as well as activities of daily living, balance and things they can do that will improve how they can move around, stay healthy, and stay connected," says Saylor.

The YMCA's mission to provide health equity also helps communities that are disproportionately impacted by disasters like the pandemic and recent winter storm. The organization has set up food drives and even put warming centers in place during Winter Storm Uri.

"That's what makes us not a gym. We're going to open our facility for you to come and get a hot shower, unlike a big box gym. We're going to do that because it's not about fitness; it's about making sure basic needs are met," says Saylor.

Saylor knows that communities of color as well as the senior population, who may be on a restricted income, can benefit from the tool.

"It really helps them become stronger, healthier, and attach to something. That connectedness is worth its weight in gold," she says.

The YMCA of Greater Houston adds content to HTX+ on a weekly basis, and Saylor says programming will continue to grow long after the pandemic.

"Now that people have been exposed and have integrated digital into their life, regardless of when the pandemic ends, I believe that will always be a part of our new way of life," she says.

"Digital is never final. It's going to take our whole team and our whole community to work together to continue to meet those digital needs because it's not going anywhere," she continues.

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Houston brain health co. secures $6.5M for rare disease study

neuro funding

Houston-based Goldenrod Therapeutics, part of Fannin Partners' portfolio, has announced the initial close of a $6.5 million series seed preferred stock round.

The round was led by Ataxia Ventures and an affiliate of Fannin, according to a news release.

Goldenrod Therapeutics plans to use the funding to support manufacturing, formulation optimization, IND-enabling studies and a Phase I study of its drug to treat brain inflammation, known as 11h.

The study will consider how 11h, which blocks the enzyme PDE4, could treat Friedreich’s ataxia (FA), a rare genetic disease that affects movement, speech and balance. To date, other PDE4 inhibitors have proven to regulate neuroinflammation and neuronal signaling, but have had adverse gastrointestinal side effects or have not reached enough of the central nervous system, according to Goldenrod.

The company says its 11h is expected to have "broad applicability" with limited emetric side effects.

“Our 11h program is a next-generation, orally bioavailable, brain-penetrant PDE4 inhibitor, where researchers overcame longstanding limitations associated with earlier PDE4 inhibitors," Dr. Dev Chatterjee, CEO of Goldenrod, said in the news release. "We believe this creates the potential for a best-in-class therapy for Friedreich’s Ataxia and a potential foundation for development across multiple neurodegenerative and neuroinflammatory disorders.”

11h was first developed at the University of Nebraska Medical Center (UNeMed). Houston-based Fannin Partners in-licensed the product 2020 and landed SBIR Phase I funding to support its initial development for opioid use disorder soon after.

Goldenrod has also received funding to study 11h's effectiveness for multiple sclerosis, methamphetamine addiction and cocaine addiction.

Goldenrod says it is developing 11h to target a variety of neurological and inflammatory conditions, including Alzheimer's disease, multiple sclerosis, ALS, substance use disorders, Batten disease, pain and traumatic brain injury.

27 Houston companies make Fortune 500 for 2026, led by energy giants

Houston HQs

Editor's note: This article has been updated to correct the number of companies based in the Dallas-Fort Worth area.

Houston is a giant among U.S. hubs for corporate headquarters.

The 2026 Fortune 500 lists 27 companies based in the Houston area, with many energy companies claiming top spots. Houston ties with Chicago for the second-most Fortune 500 headquarters, preceded only by New York City (53). Dallas-Fort Worth is home to 24 Fortune 500 headquarters.

Texas leads the nation for Fortune 500 headquarters (57), with California in the No. 2 spot and New York at No. 3.

“Texas is the undisputed headquarters of headquarters,” Gov. Greg Abbott said in a news release. “The world’s leading businesses invest with confidence in Texas because of our welcoming business climate, predictable regulatory environment, and skilled and growing workforce. People and businesses are choosing Texas because Texas works.”

The 2026 Fortune 500 ranks the largest U.S. corporations based on revenue in fiscal year 2025.

Here’s a rundown of the 27 Fortune 500 companies based in the Houston area.

  • No. 9 ExxonMobil
  • No. 21 Chevron
  • No. 29 Phillips 66
  • No.55 Sysco
  • No. 75 ConocoPhillips
  • No. 89 Enterprise Products Partners
  • No. 103 Plains GP Holdings
  • No. 133 Hewlett Packard Enterprise
  • No. 149 NRG Energy
  • No. 157 Quanta Services
  • No. 164 Baker Hughes
  • No. 173 Occidental Petroleum
  • No. 179 Waste Management
  • No. 201 EOG Resources
  • No. 204 Group 1 Automotive
  • No. 207 Halliburton
  • No. 223 Cheniere Energy
  • No. 236 Corebridge Financial
  • No. 262 Targa Resources
  • No. 266 Kinder Morgan
  • No. 388 Westlake
  • No. 435 CenterPoint Energy
  • No. 438 APA
  • No. 440 Comfort Systems USA
  • No. 455 NOV
  • No. 488 KBR
  • No. 496 Coterra Energy. Oklahoma City, Oklahoma-based Devon Energy and Houston-based Coterra Energy merged in early May, with the combined company retaining the Devon Energy name and the Houston headquarters.

The Greater Houston Partnership notes the Houston area soon will welcome its 28th Fortune 500 company. Expand Energy (formerly Chesapeake Energy), appearing at No. 362 on the 2026 list, says it’s moving its headquarters from Oklahoma City to Spring this year.

As the natural gas producer prepares to relocate to Texas, it’s hunting for a new leader. Nick Dell’Osso stepped down as president and CEO earlier this year. Board Chairman Michael Wichterich is interim president and CEO.

Dell’Osso became president and CEO of Oklahoma City-based Gulfport Energy effective May 28.

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This article first appeared on EnergyCapitalHTX.com.

Elon Musk's SpaceX is about to make its debut on Wall Street

Money Moves

Elon Musk's rocket company SpaceX will make its debut on Wall Street Friday, June 12, and both institutional and retail investors are expected to gobble up the 555.6 million shares going up for sale at $135 apiece. Musk, already the world's richest man, could become its first trillionaire.

SpaceX is likely to become the biggest IPO ever, with proceeds of around $75 billion. SpaceX hopes to become the first company to send people to Mars. In fact, part of Musk’s future compensation depends on SpaceX eventually establishing a colony of at least 1 million people on the red planet.

Why SpaceX is going public now

In a video conference on Musk's social media platform X, he told JPMorgan CEO Jamie Dimon that people have suggested for the last 10 years that he take SpaceX public. He's doing it now because the company plans to put 100,000 next-generation Starlink satellites into orbit. Deploying AI data centers in space is a “massive new growth base and you need capital for that,” he said.

Going public provides access to the capital that SpaceX needs. But it also exposes it to more scrutiny from shareholders and more regulatory oversight. That includes filing quarterly financial reports, which critics say incentivizes short-term thinking over longer-term planning and creates unnecessary costs for a company. Securities regulators are currently soliciting public comment on a proposal to require public companies to file the financial reports only twice every year.

How the IPO impacts the company

Musk will hold the majority of a special class of shares, giving him control over decisions related to company strategy, finances and personnel. On the latter, because of his ownership of most of these Class B shares, the only person who can fire Musk as CEO is Musk.

The company credits Musk with being the “driving force” behind its growth, innovation and success. But what happens if Musk is no longer in the picture? SpaceX warns that the loss of Musk could disrupt its ability to execute its strategy as well as hurt its “reputation and relationships with customers, partners and other stakeholders.”

The company also warns that finding a replacement with the same skills and experience as Musk would be time-consuming, if not nearly impossible. As Wedbush Securities analyst Dan Ives wrote Wednesday, “At the end of the day Musk is SpaceX and SpaceX is Musk.”

What could make or break SpaceX

Currently in the test phase, the gigantic reusable Starship rocket is key to SpaceX realizing Musk's ambitions. Much of the commercial space business hinges on SpaceX developing Starship’s capability to be fully reusable and hearty enough for a quick turnaround between flights. If that doesn't happen, SpaceX warns that putting data centers and satellites in space will take longer and cost more money, meaning it risks customers bailing on the company.

Analysts say that by pioneering reusable rockets, SpaceX has established a clear lead on competitors such as Blue Origin, led by Amazon founder Jeff Bezos. The Starlink satellite business competes with, among others, AST SpaceMobile – which is relying on a SpaceX rocket to send its latest generation of satellites into orbit next week.

The prospectus filed last week says SpaceX’s biggest potential market is the sale of business-oriented artificial intelligence products designed to transform how people get work done. It’s an opportunity SpaceX predicts would be worth $22.7 trillion if it could somehow dominate rivals like Anthropic, OpenAI and Microsoft in a highly competitive industry. But the prospectus shows no clear path to profitability for the xAI business, which merged with SpaceX earlier this year.

Why Wall Street is paying attention

If the SpaceX IPO is as successful, the stock could quickly join the Nasdaq 100, a widely followed index that tracks the 100 largest non-financial companies in the composite. That's important because some popular funds, such as the $460 billion QQQ exchange-traded fund, mimic the index and will automatically buy whatever is listed in the index.

Nasdaq recently changed its rules to allow select companies to enter the Nasdaq 100 after just 15 trading days.

S&P Dow Jones Indices, on the other hand, is sticking to established and more traditional thresholds that will not allow SpaceX or other companies with gargantuan IPOs faster entry into its S&P 500 index. That means even high-profile companies will still need to wait for their stocks to trade a full 12 months before they can enter the index.

Companies want to be in the S&P 500 in particular because it's arguably the most important index on Wall Street, with trillions of dollars either mimicking it exactly or benchmarked against it. Vanguard's VOO fund that tracks the S&P 500 has roughly $950 billion invested in it, for example.