Lodgeur provides its guests with hotel luxury with room to breathe. Courtesy of Lodgeur

In 2018, Houston set a new tourism record with 22.3 million visitors to the city. That same year, Sébastien Long was finishing his Cambridge thesis on home-sharing companies like Airbnb and falling in love with a classmate. When the couple moved to Houston after graduation, Long brought his ideas with him, and that's how Lodgeur was born.

Lodgeur works as an upscale home-sharing startup that offers luxury apartments in midtown and downtown Houston for nightly rent. It doesn't replace Airbnb; customers can browse through and book the properties through the familiar website. Guests can also book short or extended stays directly with Lodgeur's website.

In short, Long's research found that most Airbnb's have high guest experience ratings, but those user reviews don't work to inspire the 90 percent of Americans who haven't used a homestay service. Those people have worries — mostly about what to expect, about safety, and about having to interact with homeowners. Long believes he can calm those fears by building a trusted brand that customers recognize on Airbnb, and Houston turned out to be the perfect place to do that: his main inspiration, Conrad Hilton, did the same with hotels over the last century.

"Houston has been a city that's been overlooked. Most companies didn't come here first," Long says. "Actually, people are coming to Houston every week of the year, prices don't fluctuate too much, and you're probably going to be running at a high occupancy every week of the year."

So Long drove around the city, looking for apartment buildings he liked and hoped his guests would, too. Having grown up working at the campground-turned-resort started by his parents in the French Mediterranean, he had an eye for what tourists found attractive — buildings with character, high-end aesthetics and clean designs like a hotel, but with modern kitchen appliances and more space.

"We're roughly split between leisure guests and business travelers," Long says. "They want to feel like they're staying in a home away from home."

Getting that experience is about the same price as a hotel. The properties range from $90 per night to a $200 apartment with 50 feet of floor-to-ceiling windows overlooking downtown. The apartments have not just attracted outside visitors; people have come from around Houston to stay during home renovations or when their houses have flooded, Long says.

The first guests arrived in mid-April. Long wanted to open by managing just a few properties, to make sure the company could ensure great guest experiences.

Last week, he hired his first full-time employee — an ex-marine who graduated from the University of Houston's Conrad Hilton College of Hospitality — and has contracted a marketing agency to turn up Lodgeur's social media presence. For now, Lodgeur relies on a freelance interior designer to fashion the apartments and a local housekeeping company to keep them clean.

Long — who is a Station Houston and WeWork Labs member — says he is looking to expand, but he wants to do so organically: Many of the owners of properties he's already renting own other apartment complexes, and he plans to work with them to move Lodgeur out of inner Houston, and then to other cities. Lodgeur isn't raising funds yet, but Long says he'll be looking for investors this summer.

Recently, Long stayed at Hilton in Austin — his first time at a hotel since launching Lodgeur. He booked a room with a king-sized bed, but it felt small. Business requires him to carry a tape measure, so he measured the mattress: it was six inches smaller than the mattresses Lodgeur uses. He laughed, thinking of how much more comfortable guests would be in an apartment with bigger beds and more space.

"I don't know how people would go back (to hotels)," he says.

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Houston brain health co. secures $6.5M for rare disease study

neuro funding

Houston-based Goldenrod Therapeutics, part of Fannin Partners' portfolio, has announced the initial close of a $6.5 million series seed preferred stock round.

The round was led by Ataxia Ventures and an affiliate of Fannin, according to a news release.

Goldenrod Therapeutics plans to use the funding to support manufacturing, formulation optimization, IND-enabling studies and a Phase I study of its drug to treat brain inflammation, known as 11h.

The study will consider how 11h, which blocks the enzyme PDE4, could treat Friedreich’s ataxia (FA), a rare genetic disease that affects movement, speech and balance. To date, other PDE4 inhibitors have proven to regulate neuroinflammation and neuronal signaling, but have had adverse gastrointestinal side effects or have not reached enough of the central nervous system, according to Goldenrod.

The company says its 11h is expected to have "broad applicability" with limited emetric side effects.

“Our 11h program is a next-generation, orally bioavailable, brain-penetrant PDE4 inhibitor, where researchers overcame longstanding limitations associated with earlier PDE4 inhibitors," Dr. Dev Chatterjee, CEO of Goldenrod, said in the news release. "We believe this creates the potential for a best-in-class therapy for Friedreich’s Ataxia and a potential foundation for development across multiple neurodegenerative and neuroinflammatory disorders.”

11h was first developed at the University of Nebraska Medical Center (UNeMed). Houston-based Fannin Partners in-licensed the product 2020 and landed SBIR Phase I funding to support its initial development for opioid use disorder soon after.

Goldenrod has also received funding to study 11h's effectiveness for multiple sclerosis, methamphetamine addiction and cocaine addiction.

Goldenrod says it is developing 11h to target a variety of neurological and inflammatory conditions, including Alzheimer's disease, multiple sclerosis, ALS, substance use disorders, Batten disease, pain and traumatic brain injury.

27 Houston companies make Fortune 500 for 2026, led by energy giants

Houston HQs

Editor's note: This article has been updated to correct the number of companies based in the Dallas-Fort Worth area.

Houston is a giant among U.S. hubs for corporate headquarters.

The 2026 Fortune 500 lists 27 companies based in the Houston area, with many energy companies claiming top spots. Houston ties with Chicago for the second-most Fortune 500 headquarters, preceded only by New York City (53). Dallas-Fort Worth is home to 24 Fortune 500 headquarters.

Texas leads the nation for Fortune 500 headquarters (57), with California in the No. 2 spot and New York at No. 3.

“Texas is the undisputed headquarters of headquarters,” Gov. Greg Abbott said in a news release. “The world’s leading businesses invest with confidence in Texas because of our welcoming business climate, predictable regulatory environment, and skilled and growing workforce. People and businesses are choosing Texas because Texas works.”

The 2026 Fortune 500 ranks the largest U.S. corporations based on revenue in fiscal year 2025.

Here’s a rundown of the 27 Fortune 500 companies based in the Houston area.

  • No. 9 ExxonMobil
  • No. 21 Chevron
  • No. 29 Phillips 66
  • No.55 Sysco
  • No. 75 ConocoPhillips
  • No. 89 Enterprise Products Partners
  • No. 103 Plains GP Holdings
  • No. 133 Hewlett Packard Enterprise
  • No. 149 NRG Energy
  • No. 157 Quanta Services
  • No. 164 Baker Hughes
  • No. 173 Occidental Petroleum
  • No. 179 Waste Management
  • No. 201 EOG Resources
  • No. 204 Group 1 Automotive
  • No. 207 Halliburton
  • No. 223 Cheniere Energy
  • No. 236 Corebridge Financial
  • No. 262 Targa Resources
  • No. 266 Kinder Morgan
  • No. 388 Westlake
  • No. 435 CenterPoint Energy
  • No. 438 APA
  • No. 440 Comfort Systems USA
  • No. 455 NOV
  • No. 488 KBR
  • No. 496 Coterra Energy. Oklahoma City, Oklahoma-based Devon Energy and Houston-based Coterra Energy merged in early May, with the combined company retaining the Devon Energy name and the Houston headquarters.

The Greater Houston Partnership notes the Houston area soon will welcome its 28th Fortune 500 company. Expand Energy (formerly Chesapeake Energy), appearing at No. 362 on the 2026 list, says it’s moving its headquarters from Oklahoma City to Spring this year.

As the natural gas producer prepares to relocate to Texas, it’s hunting for a new leader. Nick Dell’Osso stepped down as president and CEO earlier this year. Board Chairman Michael Wichterich is interim president and CEO.

Dell’Osso became president and CEO of Oklahoma City-based Gulfport Energy effective May 28.

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This article first appeared on EnergyCapitalHTX.com.