Here's how Texas towns stacked up on a new population report. Photo via Getty Images

One Houston suburb experienced one of the most rapid growth spurts in the country last year: Fulshear, whose population grew by 25.6 percent, more than 51 times that of the nation’s growth rate of 0.5 percent. The city's population was 42,616 as of July 1, 2023.

According to U.S. Census Bureau's Vintage 2023 Population Estimates, released Thursday, May 16, Fulshear — which lies west of Katy in northwest Fort Bend County - ranked No. 2 on the list of fastest-growing cities with a population of 20,000 or more. It's no wonder iconic Houston restaurants like Molina's Cantina see opportunities there.

The South still dominates the nation's growth, even as America’s Northeast and Midwest cities are rebounding slightly from years of population drops. The census estimates showed 13 of the 15 fastest-growing cities in the U.S. were in the South — eight in Texas alone.

The Texas cities joining Fulshear on the fastest-growing-cities list are:

  • Celina (No. 1) with 26.6 percent growth (42,616 total population)
  • Princeton (No. 3) with 22.3 percent growth (28,027 total population)
  • Anna (No. 4) with 16.9 percent growth (27,501 total population)
  • Georgetown (No. 8) with 10.6 percent growth (96,312 total population)
  • Prosper (No. 9) with 10.5 percent growth (41,660 total population)
  • Forney (No. 10) with 10.4 percent growth (35,470 total population)
  • Kyle (No. 11) with 9 percent growth (62,548 total population)

Texas trends
San Antonio saw the biggest growth spurt in the United States last year, numbers-wise. The Alamo City added about 22,000 residents. San Antonio now has nearly 1.5 million people, making it the the seventh largest city in the U.S. and second largest in Texas.

Its population boom was followed by those of other Southern cities, including Fort Worth; Charlotte, North Carolina; Jacksonville, Florida; and Port St. Lucie, Florida.

Fast-growing Fort Worth (978,000) surpassed San Jose, California (970,000) to become the 12th most populous city in the country.

Meanwhile, population slowed in the Austin area. Jacksonville, Florida (986,000), outpaced Austin (980,000), pushing the Texas capital to 11th largest city in the U.S. (barely ahead of Fort Worth).

Population growth in Georgetown, outside Austin, slowed by more than one-fourth its population growth in 2022, the report says, from 14.4 percent to 10.6 percent. It's the same story in the Central Texas city of Kyle, whose population growth decreased by nearly 2 percent to 9 percent in 2023.

Most populated cities
New York City with nearly 8.3 million people remained the nation's largest city in population as of July 1, 2023. Los Angeles was second at close to 4 million residents, while Chicago was third at 2.7 million and Houston was fourth at 2.3 million residents.

The 15 populous U.S. cities in 2023 were:

  1. New York, New York (8.3 million)
  2. Los Angeles, California (4 million)
  3. Chicago, Illinois (2.7 million)
  4. Houston, Texas (2.3 million)
  5. Phoenix, Arizona (1.7 million)
  6. Philadelphia, Pennsylvania (1.6 million)
  7. San Antonio (1.5 million)
  8. San Diego, California (1.4 million)
  9. Dallas (1.3 million)
  10. Jacksonville, Florida (986,000)
  11. Austin (980,000)
  12. Fort Worth (978,000)
  13. San Jose (970,000)
  14. Columbus, Ohio (913,000)
  15. Charlotte, North Carolina (911,000)

Modest reversals of population declines were seen last year in large cities in the nation's Northeast and Midwest. Detroit, for example, which grew for the first time in decades, had seen an exodus of people since the 1950s. Yet the estimates released Thursday show the population of Michigan’s largest city rose by just 1,852 people from 631,366 in 2022 to 633,218 last year.

It's a milestone for Detroit, which had 1.8 million residents in the 1950s only to see its population dwindle and then plummet through suburban white flight, a 1967 race riot, the migration to the suburbs by many of the Black middle class and the national economic downturn that foreshadowed the city's 2013 bankruptcy filing.

Three of the largest cities in the U.S. that had been bleeding residents this decade staunched those departures somewhat. New York City, which has lost almost 550,000 residents this decade so far, saw a drop of only 77,000 residents last year, about three-fifths the numbers from the previous year.

Los Angeles lost only 1,800 people last year, following a decline in the 2020s of almost 78,000 residents. Chicago, which has lost almost 82,000 people this decade, only had a population drop of 8,200 residents last year.

And San Francisco, which has lost a greater share of residents this decade than any other big city — almost 7.5 percent — actually grew by more than 1,200 residents last year.

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This article originally ran on CultureMap.

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7+ can't-miss Houston business and innovation events in June 2026

where to be

Editor's note: The FIFA World Cup comes to Houston this month, joined by major energy conferences and a lineup of fan-favorite, recurring events. Here’s what not to miss and how to register. Please note: this article may be updated to add more events.


June 1-4 — CLEANPOWER 2026 Conference and Exhibition

CLEANPOWER unites policymakers, experts, and corporate leaders to solve the challenges that none can solve alone. This must-attend, four-day conference is packed with cutting-edge discussions about wind, solar, storage, and transmission; dealmaking; networking; and fun.

This event begins June 1 at the George R. Brown Convention Center. Register here.

June 2 — Humans of Healthcare

Houston Methodist Center for Innovation will present its quarterly speaker series, Humans of Healthcare. The series will feature a panel of experts who will share about their career paths and discuss the nuances of the health care industry. This month's session will focus on today’s nursing landscape, the industry’s expectations of nurses and what career paths are possible in the field.

The event is Tuesday, June 2, from 5-6:30 p.m. at the Ion. Register here.

June 9 — Greentown Go Make Kickoff

Head to the Ion to celebrate the Greentown Go Make 2026 cohort. The open-innovation program with Shell Catalysts & Technologies and Technip Energies focuses on catalytic solutions for industrial decarbonization and the energy transition. Hear pitches from the founders and network with a select group of startups while enjoying food and drink.

This event is Tuesday, June 9, from 5:30-8 p.m. Register here.

June 9-10 — Texas Brain Economy Summit

The Center for Houston’s Future and UTMB are bringing the Texas Brain Economy Summit back to Houston this summer to continue to position the region as a global leader in brain health. Expect to hear from leaders of global institutions, including the World Economic Forum, U.S. Chamber of Commerce, McKinsey Health Institute, Global Brain Economy Initiative, Davos Alzheimer’s Collaborative, Business Collaborative for Brain Health (UsAgainstAlzheimer’s), Rice University, Memorial Hermann, MD Anderson and many others. Read InnovationMap's full preview of the event here.

This event begins Tuesday, June 9. Purchase tickets here.

June 10 — MIT Future of Healthcare Technology Forum

The MIT Club of South Texas will host an in-person forum to explore how innovation, government and policy are changing the healthcare industry. The event will feature MIT alumni and Houston healthcare leaders, including Dr. Tim Boone, dean of the Texas A&M School of Engineering Medicine; Cynthia Reinhart-King, chair of bioengineering at Rice University; Dr. Tony Lin, CEO and chairman emeritus of Kelsey-Seybold Clinic; and others.

This event is Wednesday, June 10, from 5:15-8:30 p.m. at the TAMU EnMed Building. Register here.

June 11 — Goals & Gigawatts: Houston Energy & Climate Week The Power of & Kickoff Party

Come watch the Mexico City FIFA opening match while celebrating energy and innovation at the Goals & Gigawatts Kickoff Party. The event will feature food, drinks, and a showcase on Houston Energy & Climate Week. Learn what to expect and how to get involved in HECW before closing the night with a DJ and karaoke.

This event is Thursday, June 11, from 1:30-6:30 p.m. Find more information here.

June 16-17 — Energy Projects Conference & Expo

The Energy Projects Conference & Expo (EPC Show) is the largest event in North America for professionals working at the heart of major energy projects. The essential event for engineering, construction, commissioning, operations and maintenance across multiple energy sectors brings together five leading conferences under one roof. Conference subjects span LNG exporting, hydrogen and ammonia, midstream, petrochem and refining, and sustainable aviation fuels.

This event begins June 16 at George R. Brown Convention Center. Register here.

June 25 – NASA Tech Talk

Every fourth Thursday of the month, NASA experts, including longtime engineer Montgomery Goforth, present on technology development challenges NASA’s Johnson Space Center and the larger aerospace community are facing, and how they can be leveraged by Houston’s innovation community. Stick around after for drinks and networking at Second Draught.

This event is Thursday, June 25, from 6-7 p.m. at the Ion. Register here.

Houston researchers report promising first in-human trial for implantable cancer therapy

cancer breakthrough

When it comes to cancer remedies, the treatment can be as challenging for the body as its cause. But what if immunotherapy could be localized? That’s precisely what a Houston team may soon make a reality.

Rice University researchers, in partnership with MD Anderson Cancer Center, recently published their findings from the first in-human trial of an implantable cancer-fighting treatment in the journal Clinical Cancer Research. The paper details testing of AVB-001, encapsulated cells engineered to release interleukin-2 (IL-2)—a naturally occurring signaling protein that boosts immunity—in the peritoneal cavities of 14 patients. The goal is to avoid the toxicity usually experienced with less targeted treatments, as well as find a solution to IL-2s’ abbreviated half-lives.

“Traditional IL-2 therapy has shown potent antitumor activity, but its clinical use has been limited by severe side effects and delivery challenges,” Omid Veiseh, director of the Rice Biotech Launch Pad, professor of bioengineering at Rice and a senior author on the study, said in a press release. “This platform allows us to localize and sustain cytokine exposure directly where tumors reside while minimizing systemic toxicity.”

Serous ovarian carcinoma is especially well-suited to the use of AVB-001 because it tends to spread throughout the abdomen. After a minimally invasive laparoscopic procedure, patients implanted with the cells were noted to tolerate the treatment well. Half of the enrolled patients’ cancer was stabilized, with several among them reporting extended signs of benefit. No maximum tolerated dose was reached and there were no life-threatening events tied to the study.

If that sounds like less-than-earth-shaking results, this is only the beginning. The capsules were implanted for about one week because IL-2 activity drops off after that. The researchers now know that further testing should include either higher levels, repeated doses, or a combination thereof, in order to create stronger advances.

The team has already made early headway on this next step. Preclinical studies in nonhuman primates were not only tolerated well, but without added toxicity, the apes had consistent pharmacological effects.

“This is a foundational step,” Veiseh explained. “We now have evidence that the platform is safe, biologically active and potentially scalable. The next phase is optimizing dosing and exploring combination therapies to unlock its full clinical potential.”

The combination would also include a checkpoint inhibitor, which might improve AVB-001’s tumor-fighting power. “What is exciting is that we are not just delivering a drug, we are programming a microenvironment,” added Dr. Amir Jazaeri, professor of gynecologic oncology at MD Anderson, member of the Rice Biotech Launch Pad’s clinical advisory board and a senior author on the study. “This opens the door to combination strategies that could amplify immune responses in ways that have not been feasible before.”