Supporting LGBT-founded startups is crucial to Houston business success. Ylanite Koppens/Pexels

When we think about different groups within the business ecosystem in our region, the LGBTQ business community historically has not been at the table. As we close this year's Pride Month, it's time to reflect on the the importance the LGBTQ population has within Houston and local businesses.

While the LGBTQ community has realized historic gains, such as marriage equality, serious gaps in legal protections remain, resulting in discrimination in employment, housing and public accommodations. In fact, there are twenty-nine states where a person can be fired for their sexual orientation or gender identity. That kind of job insecurity coupled with an entrepreneurial spirit has driven many in the LGBTQ community to start their own businesses.

Many LGBTQ-owned businesses in the region are obtaining the LGBTBE® certification, opening the door for these business owners to participate in corporate supplier diversity programs such as those offered by Fortune 500 corporations like Bank of America, Chevron, Shell. and United. These and many other companies greatly value diverse suppliers as part of their supply chain inclusivity goals and they embrace the diversity that LGBTQ businesses bring as part of that inclusion equation. The LGBTBE® certification is part of supplier diversity and inclusion programs that typically include participation of businesses owned by minorities, veterans, and women as examples.

The Greater Houston LGBT Chamber of Commerce is hosting its annual Pride in Business Celebration on Friday, June 28, at 5:30 pm at the Hyatt Regency Houston. Click here for more information.

Why get certified?

Traditionally, LGBTQ business owners have been excluded from these opportunities within the broader business community and many have stayed in the closet because of the fear of losing clients, employees, and revenue. In fact, many LGBTQ business owners can experience a coming out process in their professional life that is entirely different from the one they have experienced in their personal life. The LGBTBE® certification gives LGBTQ owned businesses an opportunity to participate in contracting opportunities and to be valued for the service or product they provide, as well as because of who they are as LGBTQ suppliers and as part of an ecosystem of diverse entrepreneurs.

How does a business qualify for the certification?

A company must be at least 51 percent LGBTQ-owned, operated, managed, and controlled along with other criteria comparable to similar certification programs. The certifying body for the LGBTBE® certification is the National LGBT Chamber of Commerce (NGLCC). In order to get certified, a business owner should complete the application through the NGLCC.

Greater Houston LGBT Chamber members are eligible for a fee waiver, as part of the Houston chamber's affiliate relationship with the NGLCC. This is a "win-win" for businesses with the waiver of the fee and the opportunity to take advantage of the many benefits and support offered to LGBTQ entrepreneurs through the Chamber.

What's the impact?

Making sure that the LGBTQ business community has access to economic opportunity is good for business and good our region. Looking forward to the goal of full and equal rights for the LGBTQ community, economic opportunity is a key milestone for LGBTQ entrepreneurs and the community as a whole. The LGBTQ business community is part of the economic fabric in our region and key to Houston's economic success.

While the LGBTQ business community is poised for tremendous growth in the region as corporations and consumers seek out LGBTQ-supportive businesses, the traditional barriers for LGBTQ-owned businesses must be removed and economic opportunity a priority whether through the LGBTBE® certification or actively engaging LGBTQ entrepreneurs with the broader business community.


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Tammi Wallace is the co-founder and board chair of the Greater Houston LGBT Chamber of Commerce. She is also the founder and principal consultant of EnFocus Group, which connects organizations to the power of LGBTQ diversity and inclusion through training and consulting.

From opening Nap Bar and consulting corporations on diversity and inclusion to serving the city as an LGBT adviser, Khaliah Guillory is focused on productivity. Courtesy of Khaliah Guillory

From nap research to diversity and inclusion, this entrepreneur is making Houston workers more productive

Featured Innovator

Khaliah Guillory is an avid napper — and she's had to be. A multiple hat wearer and big proponent of side hustles, she's always piled responsibilities high on her plate.

Earlier this year left a corporate leadership position to open Nap Bar in Rice Village, but for years before that, she had her diversity and inclusion side hustle, KOG & Company. She works with companies — big and small — to integrate the best diversity and inclusion initiatives into the workplace.

"The intersection between KOG and Nap Bar and the common denominator is productivity and performance," Guillory says. "From a corporate standpoint — even when you think about diversity and inclusion — it all boils down to we want people who don't look like us or don't come from where we come from to be productive and perform well."

Guillory, who is this week's Pride Month Featured Innovator on InnovationMap, also serves on Mayor Sylvester Turner's LGBT Advisory Board.

InnovationMap: When did you know you wanted to be an entrepreneur?

Khaliah Guillory: I was 8 or 9 years old, and my family drank a lot of soda. Where I grew up in Port Arthur, Texas, you could go and trade in cans for change. I would go outside, line up all the cans, and step on them to crush them. I saw an infomercial about a can crusher. It made my business more efficient. That's when my entrepreneurial journey started.

IM: How did The Nap Bar come about? 

KG: I have always been an avid napper. When I was in Kindergarten, and the teacher would say go grab your red or blue mat, I did it and I was out. I enjoyed naptime. In high school, I played basketball and I napped at the end of school. When I got into college, I played basketball at the University of Central Florida. My days would start at 5 am and wouldn't end until midnight. The only way I was able to graduate on time and maintain my grades for my scholarships was napping. It just continued throughout my professional career, and I started napping in my car.

One day, my wife and I commuted into the city — we live in the Sugar Land/Richmond area. We had about an hour and a half to spare. It was nap time, but it would be awkward with her in the car. She suggested Googling naps in Houston. She says, "We live in Houston, there's got to be a place where you could take a quick nap." There was no such place. She told me I should create it. That was April of last year.

IM: Then what did you do to get the ball rolling?

KG: The next day I surveyed all my friends and asked them if I was the only one out here napping. I quickly realized that I wasn't. Specifically, 52 percent of Americans, according to Amerisleep, admitted to napping at work. I committed to doing more research. I've committed 10,000 plus hours to researching the benefits to napping and the indicators of sleep exhaustion. Fast forward to November of last year, I transitioned away from my C-level position at a Fortune 500 company to really pursue Nap Bar.

IM: How’s business been?

KG: We just celebrated our 30th day of business a couple of weeks ago. We are already generating revenue. We are excited for what's to come. June is shaping up to be a real opportunity for us to be in the black, and July is shaping up to have a lot of events. We found that our biggest challenge is educating the masses on the benefits of taking a chill session in the middle of the day, and also educating on the indicators of what it's like to be sleep deprived.

IM: With KOG & Company, your other company, you’ve worked for years with large companies to help incorporate diversity and inclusion. How does that tie into your nap research?

KG: The intersection between KOG and Nap Bar and the common denominator is productivity and performance. From a corporate standpoint — even when you think about diversity and inclusion — it all boils down to we want people who don't look like us or don't come from where we come from to be productive and perform well. The best place for any corporation that has a philosophy or a vision of values and embraces corporate social responsibility is to acknowledge that people are going to be the heartbeat of their company.

IM: What do organizations — from startups to Fortune 500 companies — need to know about diversity and inclusion?

KG: The biggest thing is that from a culture standpoint, just simply hiring people to check a box isn't going to provide the desired ROI. It really, truly has to be embraced by the culture. If I am a business owner or corporation, and my goal is to have a diversity of talent, then I need to go where those people are. If I create and curate an environment with diversity and inclusivity, then going to recruit and then ask them what type of organization they want to work for and what it would look like — then go out and build that. And if they don't know where to start, they can hire me and I can hold their hand and give some real life experience. I've lived it as a banker, as a supervisor, and as a C-level executive.

IM: What’s surprised you about being on Mayor Sylvester Turner’s LGBT Advisory Board?

KG: I think what surprised me most about is that the city of Houston is really progressing and striving. It just makes sense. We're the most diverse city in the country, and I applaud Mayor Sylvester Turner for assembling the LGBT Advisory Board and for appointing me.

The city of Houston — and all the entities that fall under it from a government landscape — is desiring a journey to get more training and education. How do we educate on how to report a hate crime. How do we make sure that city employees are showing up to work and are 100 percent comfortable in their own skin. The biggest surprise I'd have to say is that the city has done an incredible job with the training. I walked away from the meeting learning things that I didn't even know about the LGBTQ community.

IM: What does Pride Month mean to you?

KG: Pride means to me being comfortable in my skin as I am, who I am. The month is a pleasant reminder to be "me" every day, all day. Pride month means my uniqueness is celebrated, not tolerated which should be the norm everyday; not just a month. Pride means being secure in the community — workplace, networking event, the gym, basically everywhere — and confidently say "my wife."

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Portions of this interview have been edited.

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Rice Alliance and the Ion leader Brad Burke to retire this summer

lasting legacy

Brad Burke—a Rice University associate vice president who leads the Ion District’s Rice Alliance for Technology and Entrepreneurship and is a prominent figure in Houston’s startup community—is retiring this summer after a 25-year career at the university.

Burke will remain at the Rice Alliance as an adviser until his retirement on June 30.

“Brad’s impact on Rice extends far beyond any single program or initiative. He grew the Rice Alliance from a promising campus initiative into one of the most respected university-based entrepreneurship platforms,” Rice President Reginald DesRoches said in a news release.

During Burke’s tenure, the Rice Business School went from unranked in entrepreneurship to The Princeton Review’s No. 1 graduate entrepreneurship program for the past seven years and a top 20 entrepreneurship program in U.S. News & World Report’s rankings for the past 14 years.

“Brad didn’t just build programs — he built an ecosystem, a culture, and a reputation for Rice that now resonates around the world,” said Peter Rodriguez, dean of the business school. “Through his vision and steady leadership, Rice became a place where founders are taken seriously, ideas are rigorously supported, and entrepreneurship is embedded in the fabric of the university.”

One of Burke’s notable achievements at Rice is the creation of the Rice Business Plan Competition. During his tenure, the competition has grown from nine student teams competing for $10,000 into the world’s largest intercollegiate competition for student-led startups. Today, the annual competition welcomes 42 student-led startups that vie for more than $1 million in prizes.

Away from Rice, Burke has played a key role in cultivating entrepreneurship in the energy sector: He helped establish the Energy Tech Venture Forum along with Houston Energy and Climate Startup Week.

Furthermore, Burke co-founded the Texas University Network for Innovation and Entrepreneurship in 2008 to bolster the entrepreneurship programs at every university in Texas. In 2016, the Rice Alliance assumed leadership of the Global Consortium of Entrepreneurship Centers.

In 2023, Burke received the Trailblazer Award at the 2023 Houston Innovation Awards and was recognized by the Deshpande Foundation for his contributions to innovation and entrepreneurship in higher education.

“Working with an amazing team to build the entrepreneurial ecosystem at Rice, in Houston, and beyond has been the privilege of my career,” Burke said in the release. “It has been extremely gratifying to hear entrepreneurs say our efforts changed their lives, while bringing new innovations to market. The organization is well-positioned to help drive exponential growth across startups, investors, and the entrepreneurial ecosystem.”

Starting April 15, John “JR” Reale Jr. will serve as interim associate vice president at Rice and executive director of the Rice Alliance. He is managing director of the alliance and co-founder of Station Houston, beginning April 15. Reale is co-founder of the Station Houston startup hub and a startup investor and was also recently named director for startups and investor engagement for the Ion.

“The Rice Alliance has always been about helping founders gain advantages to realize their visions,” Reale said. “Under Brad’s leadership, the Rice Alliance has become a globally recognized platform that is grounded in trust and drives transformational founder outcomes. My commitment is to honor what Brad has built and led while continuing to serve our team and community, deepen relationships and deliver impact.”

Burke joined the Houston Innovators Podcast back in 2022. Listen to the full interview here.

Houston team uses CPRIT funding to develop nanodrug for cancer immunotherapy

cancer research

With a relative five-year survival rate of 50 percent, pancreatic cancer is a diagnosis nobody wants. At 60 percent, the prognosis for lung cancer isn’t much rosier. That’s because both cancers contain regulatory B cells (Bregs), which block the body’s natural immunity, making it harder to fight the enemies within.

Newly popular immunotherapies in a category known as STING agonists may stimulate natural cancer defenses. However, they can also increase Bregs while simultaneously causing significant side effects. But Wei Gao, assistant professor of pharmacology at the University of Houston College of Pharmacy, may have a solution to that conundrum.

Gao and her team have developed Nano-273, a dual-function drug, packaged in an albumin-based particle, that boosts the immune system to help it better fight pancreatic and lung cancers. Gao’s lab recently received a $900,000 grant from the Cancer Prevention and Research Institute of Texas (CPRIT) to aid in fueling her research into the nanodrug.

“Nano-273 both activates STING and blocks PI3Kγ—a pathway that drives Breg expansion, while albumin nanoparticles help deliver the drug directly to immune cells, reducing unwanted side effects,” Gao said in a press release. “This approach reduces harmful Bregs while boosting immune cells that attack cancer, leading to stronger and more targeted anti-tumor responses.”

In studies using models of both pancreatic and lung cancers, Nano-273 has shown great promise with low toxicity. Its best results thus far have involved using the drug in combination with immunotherapy or chemotherapy.

With the CPRIT funds, Gao and her team will be able to charge closer to clinical use with a series of important steps. Those include continuing to test Nano-273 alongside other drugs, including immune checkpoint inhibitors. Safety studies will follow, but with future patients in mind, Gao will also work toward improving her drug’s production, making sure that it’s safe and high-quality every time, so that it is eventually ready for trials.

Gao added: “If successful, this project could lead to a new type of immunotherapy that offers lasting tumor control and improved survival for patients with pancreatic and lung cancers, two diseases that urgently need better treatments."

Houston booms as No. 2 U.S. metro for new home construction

Construction Boom

Driven by population growth, more residential rooftops are popping up across Houston and the rest of Texas than anywhere else in America.

Using data from the U.S. Census Bureau and Zillow, Construction Coverage found 65,747 new residential units were authorized in greater Houston in 2024. That figure landed Houston in second place among major metro areas for the total number of housing permits, including those for single-family homes, apartments, and condos.

Just ahead of Houston was the Dallas-Fort Worth Metroplex, which took first place with 71,788 residential permits approved in 2024. In third place was the country’s largest metro, New York City (57,929 permits).Elsewhere in Texas, the Austin metro ranked sixth (32,294 permits), and the San Antonio metro ranked 20th (14,857 permits).

Construction Coverage also sorted major metro areas based on the number of new housing units authorized per 1,000 existing homes in 2024. Raleigh, North Carolina, held the No. 1 spot (28.8 permits per 1,000 existing homes), followed by Austin at No. 2 (28.6), DFW at No. 3 (22.2), Houston at No. 4 (21.6), and San Antonio at No. 13 (13.6).

A Newsweek analysis of Census Bureau data shows building permits for 225,756 new residential units were approved in 2024 in Texas — a trend fueled largely by activity in DFW, Houston, Austin, and San Antonio. That put Texas atop the list of states building the most residential units for the year.

Through the first eight months of last year, 145,901 permits for new residential units were approved in Texas, according to Census Bureau data. That’s nearly 80,000 permits shy of the 2024 total.

Among the states, Construction Coverage ranks Texas sixth for the number of residential building permits approved in 2024 per 1,000 existing homes (17.9).

Extra housing is being built in Texas to meet demand spurred by population growth. From April 2020 to July 2024, the state’s population increased 7.3 percent, the Census Bureau says.

While builders are busy constructing new housing in Texas, they’re not necessarily profiting a lot from homebuilding activity.

“Market conditions remain challenging, with two-thirds of builders reporting they are offering incentives to move buyers off the fence,” North Carolina homebuilder Buddy Hughes, chairman of the National Association of Home Builders, said in a December news release. “Meanwhile, builders are contending with rising material and labor prices, as tariffs are having serious repercussions on construction costs.”