Houston joins newly launched 4-city, space-focused network

space cities

The Space Cities Network launched last month with the Space City as a founding member. Photo via Houston First

Four cities from around the world have teamed up on a mission to grow aeronautics, space, and astronomy.

The Space Cities Network launched last month at the International Congress and Convention Association Congress in Abu Dhabi. The first four missions to join the initiative represent four continents and include Houston; Lausanne, Switzerland; Christchurch, New Zealand; and Seoul, South Korea.

“Space is the mirror of humanity and of our community – a quest for tomorrow. A world of exploration and innovation impacting a future that needs support and guidance. Our community, working collectively with Space experts can be one of the keystones of it, and the Space Cities Network is there to help facilitate that,” Space Cities Network Co-Chair Gerald Howard, who represents Switzerland, says in a news release.

Houston First Corp. will oversee the Space City's participation in the international alliance, which was established to increase collaboration between universities, government agencies, industry and corporations.

“Houston is proud to join this international network, leveraging our rich history in space exploration to drive innovation and collaboration across the global space sector,” Michael Heckman, president and CEO of Houston First, says in the release. “As a hub for cutting-edge research and industry, we are committed to fostering partnerships that will propel the future of aeronautics and space.”

According to the new alliance, the space economy is expected to reach $1.8 trillion by 2035, and collaboration across innovation and technology is needed to reach the industry's goals.

“Cities will play an integral, legacy role as hubs for events supporting the space community, hosting conferences, summits, and meetings that bring together industry leaders, researchers, and policymakers,” Co-Chair Claire Hector-Taylor from New Zealand, says.

Houston First Corp. will oversee the Space City's participation in the international alliance. Photo courtesy of Houston First

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Houston ranks at No. 11 in the best cities in America — and No. 1 in Texas. Getty Images

Houston scores lofty ranking in new study of America’s best cities

h-town proud

Buoyed by diversity, fine food, and Fortune 500 companies, Houston ranks as the 11th best city in the country and the top city in Texas, according to a consulting firm's annual study.

"Smart, skilled, and soulful, Houston is the American city of the future," says the study, published by Vancouver, Canada-based Resonance Consultancy Ltd., which specializes in marketing, strategy, and research for the real estate, tourism, and economic development sectors.

In last year's study, Houston also held the No. 11 ranking.

The 2020 study praises Houston for its:

  • Ethnic diversity, with more than 145 languages spoken in Houston-area homes.
  • Highly regarded restaurants, rated fourth behind Los Angeles, New York City, and Chicago.
  • Healthy concentration of Fortune 500 companies, representing the country's biggest businesses. Twenty-two companies based in the Houston area are listed on this year's Fortune 500.
  • Airport connectivity (No. 7 ranking).

The study further lauds the city for development of the Houston Spaceport, a hub for the region's space industry. However, the study notes that Houston ranks 47th for prosperity, 74th for employment, and 99th (next to last) for income equality.

"From medicine to space to energy, we are at the forefront of innovation. We are resilient problem-solvers who work together to find common solutions, no matter if we're facing Hurricane Harvey or a global pandemic," real estate developer David Mincberg, chairman of Houston First Corp., says in an August 6 release. "Houston continues to grow and get better, so we invite those who live here to rediscover our city and visitors to come as soon as it is safe and enjoy all that Houston has to offer."

Houston First promotes the city as a destination for leisure and business travelers.

Resonance Consultancy ranks large U.S. cities by relying on a mix of 26 performance and quality measures. This year, New York City tops the list, followed by Los Angeles; San Francisco; Chicago; Washington, D.C.; San Diego; Las Vegas; San Jose, California; Miami; and Boston.

Three spots behind Houston is Dallas, at No. 14. Austin comes in at No. 17 and San Antonio at No. 28. Fort Worth isn't included in the ranking.

Highlights for Dallas include:

  • No. 1 ranking for airport connectivity, thanks largely to the presence of Dallas/Fort Worth International Airport.
  • Country's highest concentration of corporate headquarters (more than 10,000).
  • Country's third largest grouping of Fortune 500 companies (24 in Dallas-Fort Worth).
  • Sixth largest LGBTQ community in the U.S.
  • Dallas Arts District, the country's largest contiguous urban arts district.

"Dallas inspires big ideas. This big and bold approach has resulted in world-class arts, culture, architecture, dining, business, and more, which are changing the face of the city," VisitDallas, the city's convention and tourism arm, says on its website.

Sitting at No. 17, Austin boasts No. 8 rankings for educational attainment and nightlife, the study says, along with a vibrant cultural scene anchored by events such as SXSW and a flourishing tech landscape dotted by the likes of Apple, Dell, Facebook, Google, and Oracle.

Austin's showing in the Resonance Consultancy study comes on the heels of the city being hailed by U.S. News & World Report as the No. 1 place to live in the country, with particularly high marks for desirability, jobs, and quality of life.

"With a strong, continually growing tech-talent labor force and an overall lower cost of living and doing business, I think Austin could end up being a beneficiary market in the recovery of the pandemic as many tech users look to move out of more densely populated areas like New York City or San Francisco," Erin Morales, senior vice president of commercial real estate services company CBRE, said in a July news release.

At No. 28, San Antonio earns kudos from Resonance Consultancy for its plethora of attractions, including the River Walk, five colonial missions, San Antonio Zoo, San Antonio Museum of Art, and Texas Golf Hall of Fame. Alamo City shows up at No. 7 in the study's attractions category.

In addition, the study highlights San Antonio's popular mixed-use Pearl district, whose assets include a campus of the Culinary Institute of America. "Around the esteemed school, a host of grads and chefs have clustered, creating a smorgasbord of choices from Italian to 'cue to bakery to vegetarian cuisine," according to the study.

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This article originally ran on CultureMap.

Houston First Corp. will sponsor the Aira technology at several venues across the city so that the blind and vision impaired can enjoy each area. Photo by Micahl Wycoff

Low-vision technology allow for the seeing impaired to have access to Houston venues

Eyes to see

A partnership between the Houston First Corporation and Aira, an app that helps blind and low-vision people gain independence by navigating tasks and public spaces, is now live at venues around the city.

Houston First will cover the costs of use for the app in its venues, including the George R. Brown Convention Center, Avenida Houston, Wortham Theater Center, and Jesse H. Jones Hall for the Performing Arts. The organization has plans to expand to the Miller Outdoor Theatre, said John Gonzalez, senior vice president of operations and general manager for Houston First.

"Technology is changing the experiences users have at our events," Gonzalez said. "We want to make our venues as accessible as possible."

California-based Aira's role in offering a vessel for facilities to be more accessible to low-vision and blind Houstonians is groundbreaking, said Vince Morvillo, an account executive with Aira who is blind.

"This technology is as important to a blind person as it is to a sighted person," Morvillo said. "You, as a person with sight, have the opportunity to look, to see things, to interact with people. When you're blind, you're not out and about; you don't have too many people to interact with. The ability to be able to go and do something when you choose to do so is really important."

The app essentially creates sight on demand. Users can use the Aira app on their smartphones and be connected to a trained operator, who will help them navigate the scene around them using video being fed to the app through their phone. The operators will then guide the user to their destination or even help them with everyday necessities like grocery shopping.

"The blind world needs this," Morvillo said. "This technology gets blind people out in the world. Businesses know how successful they are by how many people support them. I just don't understand why blind people are an untapped resource. Nobody's out there trying to get the blind shopper."

In addition to the blind population, Morvillo says that this will also help the aging population, who may often struggle with their vision later in life, and will increase accessibility options around the city.

Aira and Houston First's efforts to increase accessibility for patrons are now being recognized nationally. The National Federation of the Blind recently announced it would be bringing its annual convention to Houston in 2020.

"We are thrilled to host the group and are committed to providing a safe and enjoyable experience for all visitors," Houston First said in an email to InnovationMap. "It is our goal that Houston First venues provide an entertaining and immersive experience for all guests, and our partnership with Aira puts us one step closer to achieving that goal."

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Rice launches 'brain economy' initiative at World Economic Forum

brain health

Rice University has launched an initiative that will position “brain capital” as a key asset in the 21st century.

Rice rolled out the Global Brain Economy Initiative on Jan. 21 at the World Economic Forum in Davos, Switzerland.

“This initiative positions brain capital, or brain health and brain skills, at the forefront of global economic development, particularly in the age of artificial intelligence,” the university said in a news release.

The Rice-based initiative, whose partners are the University of Texas Medical Branch in Galveston and the Davos Alzheimer’s Collaborative, aligns with a recent World Economic Forum and McKinsey Health Institute report titled “The Human Advantage: Stronger Brains in the Age of AI,” co-authored by Rice researcher Harris Eyre. Eyre is leading the initiative.

“With an aging population and the rapid transformation of work and society driven by AI, the urgency has never been greater to focus on brain health and build adaptable human skills—both to support people and communities and to ensure long-term economic stability,” says Amy Dittmar, a Rice provost and executive vice president for academic affairs.

This initiative works closely with the recently launched Rice Brain Institute.

In its first year, the initiative will establish a global brain research agenda, piloting brain economy strategies in certain regions, and introducing a framework to guide financial backers and leaders. It will also advocate for public policies tied to the brain economy.

The report from the McKinsey Health Institute and World Economic Forum estimates that advancements in brain health could generate $6.2 trillion in economic gains by 2050.

“Stronger brains build stronger societies,” Eyre says. “When we invest in brain health and brain skills, we contribute to long-term growth, resilience, and shared prosperity.”

Rice Alliance and the Ion leader Brad Burke to retire this summer

lasting legacy

Brad Burke—a Rice University associate vice president who leads the Ion District’s Rice Alliance for Technology and Entrepreneurship and is a prominent figure in Houston’s startup community—is retiring this summer after a 25-year career at the university.

Burke will remain at the Rice Alliance as an adviser until his retirement on June 30.

“Brad’s impact on Rice extends far beyond any single program or initiative. He grew the Rice Alliance from a promising campus initiative into one of the most respected university-based entrepreneurship platforms,” Rice President Reginald DesRoches said in a news release.

During Burke’s tenure, the Rice Business School went from unranked in entrepreneurship to The Princeton Review’s No. 1 graduate entrepreneurship program for the past seven years and a top 20 entrepreneurship program in U.S. News & World Report’s rankings for the past 14 years.

“Brad didn’t just build programs — he built an ecosystem, a culture, and a reputation for Rice that now resonates around the world,” said Peter Rodriguez, dean of the business school. “Through his vision and steady leadership, Rice became a place where founders are taken seriously, ideas are rigorously supported, and entrepreneurship is embedded in the fabric of the university.”

One of Burke’s notable achievements at Rice is the creation of the Rice Business Plan Competition. During his tenure, the competition has grown from nine student teams competing for $10,000 into the world’s largest intercollegiate competition for student-led startups. Today, the annual competition welcomes 42 student-led startups that vie for more than $1 million in prizes.

Away from Rice, Burke has played a key role in cultivating entrepreneurship in the energy sector: He helped establish the Energy Tech Venture Forum along with Houston Energy and Climate Startup Week.

Furthermore, Burke co-founded the Texas University Network for Innovation and Entrepreneurship in 2008 to bolster the entrepreneurship programs at every university in Texas. In 2016, the Rice Alliance assumed leadership of the Global Consortium of Entrepreneurship Centers.

In 2023, Burke received the Trailblazer Award at the 2023 Houston Innovation Awards and was recognized by the Deshpande Foundation for his contributions to innovation and entrepreneurship in higher education.

“Working with an amazing team to build the entrepreneurial ecosystem at Rice, in Houston, and beyond has been the privilege of my career,” Burke said in the release. “It has been extremely gratifying to hear entrepreneurs say our efforts changed their lives, while bringing new innovations to market. The organization is well-positioned to help drive exponential growth across startups, investors, and the entrepreneurial ecosystem.”

Starting April 15, John “JR” Reale Jr. will serve as interim associate vice president at Rice and executive director of the Rice Alliance. He is managing director of the alliance and co-founder of Station Houston, beginning April 15. Reale is co-founder of the Station Houston startup hub and a startup investor and was also recently named director for startups and investor engagement for the Ion.

“The Rice Alliance has always been about helping founders gain advantages to realize their visions,” Reale said. “Under Brad’s leadership, the Rice Alliance has become a globally recognized platform that is grounded in trust and drives transformational founder outcomes. My commitment is to honor what Brad has built and led while continuing to serve our team and community, deepen relationships and deliver impact.”

Burke joined the Houston Innovators Podcast back in 2022. Listen to the full interview here.

Houston team uses CPRIT funding to develop nanodrug for cancer immunotherapy

cancer research

With a relative five-year survival rate of 50 percent, pancreatic cancer is a diagnosis nobody wants. At 60 percent, the prognosis for lung cancer isn’t much rosier. That’s because both cancers contain regulatory B cells (Bregs), which block the body’s natural immunity, making it harder to fight the enemies within.

Newly popular immunotherapies in a category known as STING agonists may stimulate natural cancer defenses. However, they can also increase Bregs while simultaneously causing significant side effects. But Wei Gao, assistant professor of pharmacology at the University of Houston College of Pharmacy, may have a solution to that conundrum.

Gao and her team have developed Nano-273, a dual-function drug, packaged in an albumin-based particle, that boosts the immune system to help it better fight pancreatic and lung cancers. Gao’s lab recently received a $900,000 grant from the Cancer Prevention and Research Institute of Texas (CPRIT) to aid in fueling her research into the nanodrug.

“Nano-273 both activates STING and blocks PI3Kγ—a pathway that drives Breg expansion, while albumin nanoparticles help deliver the drug directly to immune cells, reducing unwanted side effects,” Gao said in a press release. “This approach reduces harmful Bregs while boosting immune cells that attack cancer, leading to stronger and more targeted anti-tumor responses.”

In studies using models of both pancreatic and lung cancers, Nano-273 has shown great promise with low toxicity. Its best results thus far have involved using the drug in combination with immunotherapy or chemotherapy.

With the CPRIT funds, Gao and her team will be able to charge closer to clinical use with a series of important steps. Those include continuing to test Nano-273 alongside other drugs, including immune checkpoint inhibitors. Safety studies will follow, but with future patients in mind, Gao will also work toward improving her drug’s production, making sure that it’s safe and high-quality every time, so that it is eventually ready for trials.

Gao added: “If successful, this project could lead to a new type of immunotherapy that offers lasting tumor control and improved survival for patients with pancreatic and lung cancers, two diseases that urgently need better treatments."

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