Houston is the ninth worst U.S. metro for ozone pollution, but the future isn't foggy. Electric vehicles can improve air quality by 50 percent. Getty Images

Let's clear the air about Houston's air pollution: A recent report from the American Lung Association ranks Houston the ninth worst U.S. metro area for ozone pollution and the 17th worst in the broad category of long-term particle pollution.

Yet the future might not be so cloudy for Houston's atmosphere.

A newly published study in the journal Atmospheric Environment indicates that replacing at least 35 percent of Houston's gas- and diesel-powered cars and trucks with electric vehicles by 2040 could improve air quality by 50 percent. And if electric vehicles replaced 75 percent of traditional cars and trucks by 2040, air quality could improve by 75 percent, according to the study.

This conversion to electric vehicles would enable residents of the Houston area to "breathe easier, live longer, and enjoy a better economy," the researchers say.

"The population in 2040 Houston will see a huge increase, but we can apply new technology to reduce emissions, improve air quality, and think about health," says one of the researchers, Shuai Pan, a postdoctoral associate in civil and environmental engineering at Cornell University.

Pan earned a doctoral degree in atmospheric science from the University of Houston in 2017.

Kevin Douglass, president of the Houston Electric Auto Association, tells InnovationMap that the study does a good job of emphasizing "the alarming situation that Houston is in with reference to its air quality and how electrification of the transportation system is a … way to improve the bad-air-quality situation."

The nonprofit Houston Electric Auto Association comprises EV owners, hobbyists, educators, and enthusiasts who promote the benefits of these vehicles.

Douglass says he's confident about the progression of the EV evolution in Houston.

"It only took a decade to go from horse-drawn carriage to automobile in the U.S.," he says. "One and a half decades from now, in 2035, at least half of the cars on the road will be electric. Thirty years from now, the vast majority of vehicles will be electric and autonomous."

Houston — which the nonprofit Smart Energy Consumer Collaborative praises as one of the 10 friendliest U.S. cities for EVs — already is on the road toward enhancing air quality by putting more electric vehicles (EVs) on the road. In fact, a 2018 report from the Environment Texas Research and Policy Center predicts the number of EVs in Houston will rise to 65,000 by 2030.

An estimated 9,500 EVs were being driven by Houston motorists in 2018, according to a presentation given in May by Michael Conklin, external engagement manager at Houston-based utility CenterPoint Energy. And by 2028, that number could reach 110,000, the presentation says.

"Electric cars aren't the future — they're already here, and they work," Douglass said in 2018. "As more people learn about them, they will enjoy owning and driving them."

Among Houston's highest-profile EV champions is Mayor Sylvester Turner, who's leading the charge to shift the city-owned fleet away from traditional vehicles and toward hybrids and EVs.

"Transportation is responsible for 48 percent of Houston's greenhouse gas emissions — the highest per capita of all U.S. cities — and something we must address to move our city forward," Turner, co-chair of the Climate Mayors organization, said in 2018.
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Rice University lands $18M to revolutionize lymphatic disease detection

fresh funding

An arm of the U.S. Department of Health and Human Services has awarded $18 million to scientists at Rice University for research that has the potential to revolutionize how lymphatic diseases are detected and help increase survivability.

The lymphatic system is the network of vessels all over the body that help eliminate waste, absorb fat and maintain fluid balance. Diseases in this system are often difficult to detect early due to the small size of the vessels and the invasiveness of biopsy testing. Though survival rates of lymph disease have skyrocketed in the United States over the last five years, it still claims around 200,000 people in the country annually.

Early detection of complex lymphatic anomalies (CLAs) and lymphedema is essential in increasing successful treatment rates. That’s where Rice University’s SynthX Center, directed by Han Xiao and Lei Li, an assistant professor of electrical and computer engineering, comes in.

Aided by researchers from Texas Children’s Hospital, Baylor College of Medicine, the University of Texas at Dallas and the University of Texas Southwestern Medical Center, the center is pioneering two technologies: the Visual Imaging System for Tracing and Analyzing Lymphatics with Photoacoustics (VISTA-LYMPH) and Digital Plasmonic Nanobubble Detection for Protein (DIAMOND-P).

Simply put, VISTA-LYMPH uses photoacoustic tomography (PAT), a combination of light and sound, to more accurately map the tiny vessels of the lymphatic system. The process is more effective than diagnostic tools that use only light or sound, independent of one another. The research award is through the Advanced Research Projects Agency for Health (ARPA-H) Lymphatic Imaging, Genomics and pHenotyping Technologies (LIGHT) program, part of the U.S. HHS, which saw the potential of VISTA-LYMPH in animal tests that produced finely detailed diagnostic maps.

“Thanks to ARPA-H’s award, we will build the most advanced PAT system to image the body’s lymphatic network with unprecedented resolution and speed, enabling earlier and more accurate diagnosis,” Li said in a news release.

Meanwhile, DIAMOND-P could replace the older, less exact immunoassay. It uses laser-heated vapors of plasmonic nanoparticles to detect viruses without having to separate or amplify, and at room temperature, greatly simplifying the process. This is an important part of greater diagnosis because even with VISTA-LYMPH’s greater imaging accuracy, many lymphatic diseases still do not appear. Detecting biological markers is still necessary.

According to Rice, the efforts will help address lymphatic disorders, including Gorham-Stout disease, kaposiform lymphangiomatosis and generalized lymphatic anomaly. They also could help manage conditions associated with lymphatic dysfunction, including cancer metastasis, cardiovascular disease and neurodegeneration.

“By validating VISTA-LYMPH and DIAMOND-P in both preclinical and clinical settings, the team aims to establish a comprehensive diagnostic pipeline for lymphatic diseases and potentially beyond,” Xiao added in the release.

The ARPA-H award funds the project for up to five years.

Houston doctor wins NIH grant to test virtual reality for ICU delirium

Virtual healing

Think of it like a reverse version of The Matrix. A person wakes up in a hospital bed and gets plugged into a virtual reality game world in order to heal.

While it may sound far-fetched, Dr. Hina Faisal, a Houston Methodist critical care specialist in the Department of Surgery, was recently awarded a $242,000 grant from the National Institute of Health to test the effects of VR games on patients coming out of major surgery in the intensive care unit (ICU).

The five-year study will focus on older patients using mental stimulation techniques to reduce incidences of delirium. The award comes courtesy of the National Institute on Aging K76 Paul B. Beeson Emerging Leaders Career Development Award in Aging.

“As the population of older adults continues to grow, the need for effective, scalable interventions to prevent postoperative complications like delirium is more important than ever,” Faisal said in a news release.

ICU delirium is a serious condition that can lead to major complications and even death. Roughly 87 percent of patients who undergo major surgery involving intubation will experience some form of delirium coming out of anesthesia. Causes can range from infection to drug reactions. While many cases are mild, prolonged ICU delirium may prevent a patient from following medical advice or even cause them to hurt themselves.

Using VR games to treat delirium is a rapidly emerging and exciting branch of medicine. Studies show that VR games can help promote mental activity, memory and cognitive function. However, the full benefits are currently unknown as studies have been hampered by small patient populations.

Faisal believes that half of all ICU delirium cases are preventable through VR treatment. Currently, a general lack of knowledge and resources has been holding back the advancement of the treatment.

Hopefully, the work of Faisal in one of the busiest medical cities in the world can alleviate that problem as she spends the next half-decade plugging patients into games to aid in their healing.