Comicpalooza expects another record year, says Houston First Corp. executive

Featured Innovator

Michael Heckman shares about some exciting new aspects of Houston's 11th annual Comicpalooza. Courtesy of Houston First

Eleven years ago, Comicpalooza was a small event held out in Katy. Over the past few years, with the help of Houston First Corp., the three-day conference has grown to be so big, the 2019 programming will spill out of George R. Brown Convention Center and into Discovery Green, and attract over 50,000 attendees.

"These comic conventions used to just be for the hardcore pop culture fans. What we've attempted to do is make it so there's something for everyone," says Michael Heckman, Comicpalooza president and senior vice president at Houston First. "As a casual pop culture fan, there's a lot to see and do."

The festivities take place Friday, May 10, to Sunday, May 12, and include some big name events. Two Game of Thrones stars — Emilia Clarke (Daenerys Targaryen) and Nathalie Emmanuel (Missandei) — will be on a panel, and ESPN will host its first collegiate esports competition.

Heckman tells InnovationMap more about these big events and how Comicpalooza has transformed over the years.

InnovationMap: How the event has grown over the past decade? 

Michael Heckman: We've really worked hard to increase the impact of the event. There's a lot of out of town visitors that do come in — it has north of a $20 million economic impact every year. When you look at an event that is held during a traditionally slow period of time, it's a really big deal for the hotels and restaurants. The other part about it is when you're able to bring big stars to Houston, they're tweeting about it and posting Instagram stories about it. It does a lot to shine a spotlight on Houston's reputation and image.

IM: What are you most excited about for this year?

MH: It's a big sprawling event that takes place across all 1.2 million square feet of GRBCC. I'm excited about a few things. First, we've got the two folks from Game of Thrones. To be able to get Emilia Clarke in the middle of the final season of Game of Thrones, with only two episodes to go — the hype has been unbelievable. To be able to have a pop culture phenomenon like that come here to Houston — and it will be her first fan event. She's done the San Diego Comic Con, but that was more of a media event.

We've also got the ESPN Collegiate Esports Championship held here. We've done esports and gaming over the past few years, but it's a growth area for the event. To be able to hold that event with dozens of championships from around the country for this inaugural event is very exciting.

What a lot of people don't know is there are so many interesting aspects to Comicpalooza — from literature tracks to a film festival to a makerspace. There are hundreds of exhibitors on the expo showfloor, but there's an area carved out for makers. We have NASA, a cultural arts avenue, there's something for everyone. We're really looking forward to a blockbuster year.

IM: What did it mean for Houston to get ESPN’s collegiate esports program? 

MH: Esports is rapidly growing. That marketplace is developing very quickly. A lot of people and a lot of cities are figuring out what that means. We've understood the value of it for Comicpalooza for a number of years. ESPN is making a big investment — it's their first ever event of this nature, but it won't be their last.

IM: How did it come about?

MH: We've been talking to a number of folks across the landscape about how to best utilize the space that we have at GRBCC and find an opportunity that was a good fit for us. A couple people we were talking to out on the West Coast who connected us to the ESPN people, who happen to be the same division of ESPN that partners with the Houston Texans on a couple things. There's some synergies there, and they're familiar with Houston.

IM: How would you describe Comicpalooza's economic impact on Houston?

MH: Around 20 to 30 percent for the audience of Comicpalooza comes from outside of Houston. Last year, we had attendees from 47 states and 17 countries. It gives great exposure to the city, and the money they leave behind is valuable from an economic impact perspective. We think our numbers will be somewhat similar to last year.

If you look at the long term vision of what this could be, we have a beautiful campus for this event. We've moved some of our programming outside GRBCC onto the Avenida Plaza that connects to Discovery Green. If we have a full campus-wide event, that's something that's highly attractive. You grow that attendance, get up to 70 or 80 thousand people — that's a mega event. It's a snowball — once you get it started and then it just takes off. We're not there yet, but we've had really smart growth.

IM: How is the city as a whole preparing for the event?

MH: Houston's really good about handling events. It takes everything from the fire department to the police department and traffic control and 700 event volunteers — over 2,000 shifts. It's such a big footprint — it's kind of all hands on deck. It also looks like we'll have Astros at home and the Rockets playing game six of the playoffs at home. This major super block in downtown will be absolutely electric this weekend.

IM: What other events are you looking to bring to Houston?

MH: We'll always be chasing our conventions we have here. Our convention sales team looks to break another record this year. We have a lot of major events upcoming — from the college football playoff to the men's basketball Final Four, and we'll eventually pursue another Super Bowl. As we look to develop our portfolio of events that we manage here, there's a lot of opportunities here for events centered around innovation. There's a lot of talk around how Houston needs to have a better reputation for innovation. We've got aerospace, medical, oil and gas — what's an event we can create or partner on that could highlight Houston's innovation.

------

Portions of this interview have been edited.

Ad Placement 300x100
Ad Placement 300x600

CultureMap Emails are Awesome

Property Showcase

Rice launches 'brain economy' initiative at World Economic Forum

brain health

Rice University has launched an initiative that will position “brain capital” as a key asset in the 21st century.

Rice rolled out the Global Brain Economy Initiative on Jan. 21 at the World Economic Forum in Davos, Switzerland.

“This initiative positions brain capital, or brain health and brain skills, at the forefront of global economic development, particularly in the age of artificial intelligence,” the university said in a news release.

The Rice-based initiative, whose partners are the University of Texas Medical Branch in Galveston and the Davos Alzheimer’s Collaborative, aligns with a recent World Economic Forum and McKinsey Health Institute report titled “The Human Advantage: Stronger Brains in the Age of AI,” co-authored by Rice researcher Harris Eyre. Eyre is leading the initiative.

“With an aging population and the rapid transformation of work and society driven by AI, the urgency has never been greater to focus on brain health and build adaptable human skills—both to support people and communities and to ensure long-term economic stability,” says Amy Dittmar, a Rice provost and executive vice president for academic affairs.

This initiative works closely with the recently launched Rice Brain Institute.

In its first year, the initiative will establish a global brain research agenda, piloting brain economy strategies in certain regions, and introducing a framework to guide financial backers and leaders. It will also advocate for public policies tied to the brain economy.

The report from the McKinsey Health Institute and World Economic Forum estimates that advancements in brain health could generate $6.2 trillion in economic gains by 2050.

“Stronger brains build stronger societies,” Eyre says. “When we invest in brain health and brain skills, we contribute to long-term growth, resilience, and shared prosperity.”

Rice Alliance and the Ion leader Brad Burke to retire this summer

lasting legacy

Brad Burke—a Rice University associate vice president who leads the Ion District’s Rice Alliance for Technology and Entrepreneurship and is a prominent figure in Houston’s startup community—is retiring this summer after a 25-year career at the university.

Burke will remain at the Rice Alliance as an adviser until his retirement on June 30.

“Brad’s impact on Rice extends far beyond any single program or initiative. He grew the Rice Alliance from a promising campus initiative into one of the most respected university-based entrepreneurship platforms,” Rice President Reginald DesRoches said in a news release.

During Burke’s tenure, the Rice Business School went from unranked in entrepreneurship to The Princeton Review’s No. 1 graduate entrepreneurship program for the past seven years and a top 20 entrepreneurship program in U.S. News & World Report’s rankings for the past 14 years.

“Brad didn’t just build programs — he built an ecosystem, a culture, and a reputation for Rice that now resonates around the world,” said Peter Rodriguez, dean of the business school. “Through his vision and steady leadership, Rice became a place where founders are taken seriously, ideas are rigorously supported, and entrepreneurship is embedded in the fabric of the university.”

One of Burke’s notable achievements at Rice is the creation of the Rice Business Plan Competition. During his tenure, the competition has grown from nine student teams competing for $10,000 into the world’s largest intercollegiate competition for student-led startups. Today, the annual competition welcomes 42 student-led startups that vie for more than $1 million in prizes.

Away from Rice, Burke has played a key role in cultivating entrepreneurship in the energy sector: He helped establish the Energy Tech Venture Forum along with Houston Energy and Climate Startup Week.

Furthermore, Burke co-founded the Texas University Network for Innovation and Entrepreneurship in 2008 to bolster the entrepreneurship programs at every university in Texas. In 2016, the Rice Alliance assumed leadership of the Global Consortium of Entrepreneurship Centers.

In 2023, Burke received the Trailblazer Award at the 2023 Houston Innovation Awards and was recognized by the Deshpande Foundation for his contributions to innovation and entrepreneurship in higher education.

“Working with an amazing team to build the entrepreneurial ecosystem at Rice, in Houston, and beyond has been the privilege of my career,” Burke said in the release. “It has been extremely gratifying to hear entrepreneurs say our efforts changed their lives, while bringing new innovations to market. The organization is well-positioned to help drive exponential growth across startups, investors, and the entrepreneurial ecosystem.”

Starting April 15, John “JR” Reale Jr. will serve as interim associate vice president at Rice and executive director of the Rice Alliance. He is managing director of the alliance and co-founder of Station Houston, beginning April 15. Reale is co-founder of the Station Houston startup hub and a startup investor and was also recently named director for startups and investor engagement for the Ion.

“The Rice Alliance has always been about helping founders gain advantages to realize their visions,” Reale said. “Under Brad’s leadership, the Rice Alliance has become a globally recognized platform that is grounded in trust and drives transformational founder outcomes. My commitment is to honor what Brad has built and led while continuing to serve our team and community, deepen relationships and deliver impact.”

Burke joined the Houston Innovators Podcast back in 2022. Listen to the full interview here.

Houston team uses CPRIT funding to develop nanodrug for cancer immunotherapy

cancer research

With a relative five-year survival rate of 50 percent, pancreatic cancer is a diagnosis nobody wants. At 60 percent, the prognosis for lung cancer isn’t much rosier. That’s because both cancers contain regulatory B cells (Bregs), which block the body’s natural immunity, making it harder to fight the enemies within.

Newly popular immunotherapies in a category known as STING agonists may stimulate natural cancer defenses. However, they can also increase Bregs while simultaneously causing significant side effects. But Wei Gao, assistant professor of pharmacology at the University of Houston College of Pharmacy, may have a solution to that conundrum.

Gao and her team have developed Nano-273, a dual-function drug, packaged in an albumin-based particle, that boosts the immune system to help it better fight pancreatic and lung cancers. Gao’s lab recently received a $900,000 grant from the Cancer Prevention and Research Institute of Texas (CPRIT) to aid in fueling her research into the nanodrug.

“Nano-273 both activates STING and blocks PI3Kγ—a pathway that drives Breg expansion, while albumin nanoparticles help deliver the drug directly to immune cells, reducing unwanted side effects,” Gao said in a press release. “This approach reduces harmful Bregs while boosting immune cells that attack cancer, leading to stronger and more targeted anti-tumor responses.”

In studies using models of both pancreatic and lung cancers, Nano-273 has shown great promise with low toxicity. Its best results thus far have involved using the drug in combination with immunotherapy or chemotherapy.

With the CPRIT funds, Gao and her team will be able to charge closer to clinical use with a series of important steps. Those include continuing to test Nano-273 alongside other drugs, including immune checkpoint inhibitors. Safety studies will follow, but with future patients in mind, Gao will also work toward improving her drug’s production, making sure that it’s safe and high-quality every time, so that it is eventually ready for trials.

Gao added: “If successful, this project could lead to a new type of immunotherapy that offers lasting tumor control and improved survival for patients with pancreatic and lung cancers, two diseases that urgently need better treatments."

View All Listings