You can search Houston's top BBQ spots by a wide range of criteria. Courtesy of Houston BBQ Guide

Anew website wants to help Houstonians eat better barbecue. Created by the founders of the Houston BBQ Festival, the Houston BBQ Guide offers readers the ability to search for restaurants based on a wide range of criteria, including location, parking, and whether a restaurant is likely to sell out of food.

The editors of the guide, led by Houston Chronicle barbecue columnist J.C. Reid, have selected the 28 initial entries with an eye on small, family-run businesses that aim "to provide a quality product and experience on a consistent basis." Entries include both historic barbecue joints like Lenox Bar-B-Q and Pizzitola's Bar-B-Que as well as spots that have earned recognition on Texas Monthly's list of the state's 50 best such as CorkScrew BBQ and The Pit Room.

Each entry includes details about a restaurant's ownership and pitmaster, noteworthy dishes, and a brief video tour. The website also includes essays about the history of Houston's barbecue restaurants and other relevant topics.

As an "about the guide" section notes, people who want to eat barbecue may not know where to find it. By breaking things does geographically, the guide offers diners the opportunity to discover new places or be prompted to visit old favorites that aren't necessarily included in media-generated lists of the "best" barbecue restaurants.

"I like to think of it as a guide for everyday barbecue fans," Reid said in a statement.

The guide also offers an alternative to crowd-sourced review websites as well as the responses one gets on social media when a request for a restaurant near Sugar Land might be met with a suggestion to drive to Tomball — well-intentioned, surely, but not very helpful.

The guide will add new entries in time. For example, Feges BBQ's original Greenway Plaza location is listed but its newly opened Spring Branch outpost isn't (yet). A separate guide to barbecue pop-ups is already in the works, and the editors also tout the possibility of expanding to other Texas cities.

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This article originally ran on CultureMap.

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Axiom Space-tested cancer drug advances to clinical trials

mission critical

A cancer-fighting drug tested aboard several Axiom Space missions is moving forward to clinical trials.

Rebecsinib, which targets a cancer cloning and immune evasion gene, ADAR1, has received FDA approval to enter clinical trials under active Investigational New Drug (IND) status, according to a news release. The drug was tested aboard Axiom Mission 2 (Ax-2) and Axiom Mission 3 (Ax-3). It was developed by Aspera Biomedicine, led by Dr. Catriona Jamieson, director of the UC San Diego Sanford Stem Cell Institute (SSCI).

The San Diego-based Aspera team and Houston-based Axiom partnered to allow Rebecsinib to be tested in microgravity. Tumors have been shown to grow more rapidly in microgravity and even mimic how aggressive cancers can develop in patients.

“In terms of tumor growth, we see a doubling in growth of these little mini-tumors in just 10 days,” Jamieson explained in the release.

Rebecsinib took part in the patient-derived tumor organoid testing aboard the International Space Station. Similar testing is planned to continue on Axiom Station, the company's commercial space station that's currently under development.

Additionally, the drug will be tested aboard Ax-4 under its active IND status, which was targeted to launch June 25.

“We anticipate that this monumental mission will inform the expanded development of the first ADAR1 inhibitory cancer stem cell targeting drug for a broad array of cancers," Jamieson added.

According to Axiom, the milestone represents the potential for commercial space collaborations.

“We’re proud to work with Aspera Biomedicines and the UC San Diego Sanford Stem Cell Institute, as together we have achieved a historic milestone, and we’re even more excited for what’s to come,” Tejpaul Bhatia, the new CEO of Axiom Space, said in the release. “This is how we crack the code of the space economy – uniting public and private partners to turn microgravity into a launchpad for breakthroughs.”