The five finalists for Mentor of the Year in the Houston Innovation Awards sound off on their best advice. Photos courtesy

Houston is home to many great mentors — all hailing for completely different backgrounds.

At the Houston Innovation Awards Gala on November 9, InnovationMap and Houston Exponential are honoring five finalists selected by judges — and naming one winner — who have dedicated at least a portion of their lives to supporting others within the startup and tech scene in Houston.

Here are some words of wisdom from our awards honorees from the Mentor of the Year category for the 2022 Houston Innovation Awards.

"I always remind people to be open and ask for help. There is a common misconception that if you disclose your idea, someone else will quickly run with it and beat you to market! ... Don’t alienate yourself by overprotecting the idea and keeping it all to yourself. The more you open up about your idea the more feedback you’ll get, good and bad, both of which are vital in the success of the product long term."

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- Alfredo Arvide, Blue People and HOUnited. Arvide, who's been an advisor for over a decade, adds, that "most markets are big enough to allow competition to thrive, so keeping your idea behind close doors until you launch may hurt you as the market may not be ready for it. Having multiple players competing in the market will help you in the long run, as long as you have a great product and a sound marketing strategy."

"Understand the problem you are trying to solve. Build a team that works well together and has the intellect, drive, and willingness to develop and bring to market a solution for that problem. Leadership is not about giving orders and making all the decisions. It is about creating the environment for your team members individually and collectively to do their best work and be most fulfilled."

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- Barbara Burger, adviser and board member for several startups and organizations. With over 20 years of experience supporting startups, Burger says she is mostly focused on startups dedicated to decarbonizing the energy system.

"Don't have 'rocking chair regret.' What I mean is when you are old and in a rocking chair, you aren't going to regret the year (or less) you took away from a guaranteed salary to test if your idea worked. So, take the time and follow your dreams — you never know what could happen!"

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- Craig Ceccanti, T-Minus Solutions. Ceccanti, who also co-founded Pinot's Palette and Rivalry Technologies, has been mentoring for over a decade. "I love helping people and always have so helping others achieve their dreams is a natural progression for me, he says. "I've also had incredible mentors and I like to pay it forward every chance I get. I feel that mentoring is fun, therapeutic, and mutually beneficial as I feel I learn from the smart people I get to talk to daily!

"Bring great people on your journey with you — team members, advisors, investors, mentors, consultants, etc."

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- Emily Reiser, Texas Medical Center and Enventure. Reiser, who's mentored companies for several years, says it's her own mentors that inspired her. "I had excellent mentors who generously gave their time for me, especially Upendra Marathi, and it's just a given that I mentor others. It's a privilege to learn from the people I mentor and see them become successful."

"Be your own cheerleader. Stay true to yourself and don't give up."

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Kara Branch, founder of Black Girls Do Engineer Corp. "I have always been the only black woman in all my roles. As a mother of three daughters, my oldest daughter inspired Black Girls Do Engineer Corp.," Branch says. "When she daughter was 9, she came to me and said she wanted to be a software engineer. ... If anyone can help her achieve her dreams is her mom and I wanted to create a space for girls who look like my daughter to come together and do the things they love and are passionate about."

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Rice research breakthrough paves the way for advanced disease therapies

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Bioengineers at Rice University have developed a “new construction kit” for building custom sense-and-respond circuits in human cells, representing a major breakthrough in the field of synthetic biology, which could "revolutionize" autoimmune disease and cancer therapeutics.

In a study published in the journal Science, the team focused on phosphorylation, a cellular process in the body in which a phosphate group is added to a protein, signaling a response. In multicellular organisms, phosphorylation-based signaling can involve a multistage, or a cascading-like effect. Rice’s team set out to show that each cycle in a cascade can be treated as an elementary unit, meaning that they can be reassembled in new configurations to form entirely novel pathways linking cellular inputs and outputs.

Previous research on using phosphorylation-based signaling for therapeutic purposes has focused on re-engineering pathways.

“This opens up the signaling circuit design space dramatically,” Caleb Bashor, assistant professor of bioengineering and biosciences and corresponding author on the study, said in a news release. “It turns out, phosphorylation cycles are not just interconnected but interconnectable … Our design strategy enabled us to engineer synthetic phosphorylation circuits that are not only highly tunable but that can also function in parallel with cells’ own processes without impacting their viability or growth rate.”

Bashor is the deputy director for the Rice Synthetic Biology Institute, which launched last year.

The Rice lab's sense-and-respond cellular circuit design is also innovative because phosphorylation occurs rapidly. Thus, the new circuits could potentially be programmed to respond to physiological events in minutes, compared to other methods, which take hours to activate.

Rice’s team successfully tested the circuits for sensitivity and their ability to respond to external signals, such as inflammatory issues. The researchers then used the framework to engineer a cellular circuit that can detect certain factors, control autoimmune flare-ups and reduce immunotherapy-associated toxicity.

“This work brings us a whole lot closer to being able to build ‘smart cells’ that can detect signs of disease and immediately release customizable treatments in response,” Xiaoyu Yang, a graduate student in the Systems, Synthetic and Physical Biology Ph.D. program at Rice who is the lead author on the study, said in a news release.

Ajo-Franklin, a professor of biosciences, bioengineering, chemical and biomolecular engineering and a Cancer Prevention and Research Institute of Texas Scholar, added “the Bashor lab’s work vaults us forward to a new frontier — controlling mammalian cells’ immediate response to change.”

Greentown Labs names new CEO to lead pioneering climate tech incubator

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Houston and Boston climate tech incubator Greentown Labs has named Georgina Campbell Flatter as the organization’s incoming CEO.

Flatter will transition to Greentown from her role as co-founder and executive director of TomorrowNow.org, a global nonprofit that studies and connects next-generation weather and climate technologies with communities most affected by climate change.

“We are at a transformational moment in the energy transition, with an unprecedented opportunity to drive solutions in energy production, sustainability, and climate resilience,” Flatter said in a news release. “Greentown Labs is, and has always been, a home for entrepreneurs and a powerhouse of collaboration and innovation.”

Previously, Flatter worked to launch TomorrowNow out of tomorrow.io, a Boston-based AI-powered weather intelligence and satellite technology company. The organization secured millions in climate philanthropy from partners, including the Gates Foundation, which helped deliver cutting-edge climate solutions to millions of African farmers weekly.

Flatter also spent 10 years at the Massachusetts Institute of Technology (MIT), where she was a senior lecturer and led global initiatives at the intersection of technology and social impact. Her research work includes time at Langer Lab and Sun Catalytix, an MIT – ARPA-E-funded spin-out that focused on energy storage solutions inspired by natural photosynthesis. Flatter is also an Acumen Rockefeller Global Food Systems Fellow and was closely involved with Greentown Labs when it was founded in Boston in 2011, according to the release.

“It’s rare to find an individual who has impressive climate and energy expertise along with nonprofit and entrepreneurial leadership—we’re fortunate Georgie brings all of this and more to Greentown Labs,” Bobby Tudor, Greentown Labs Board Chair and Chairman of the Houston Energy Transition Initiative, said in a news release.

Flatter will collaborate with Kevin Dutt, Greentown’s Interim CEO, and also continue to serve on Greentown’s Board of Directors, which was recently announced in December and contributed to a successful $4 million funding round. She’s also slated to speak at CERAWeek next month.

“In this next chapter, I’m excited to build on our entrepreneurial roots and the strength of our ever-growing communities in Boston and Houston,” Flatter added in a news release. “Together, we will unite entrepreneurs, partners, and resources to tackle frontier challenges and scale breakthrough technologies.”

Greentown also named Naheed Malik its new chief financial officer last month. The announcements come after Greentown’s former CEO and president, Kevin Knobloch, announced that he would step down in July 2024 after less than a year in the role.

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This article originally appeared on our sister site, EnergyCapital.

Houston firm invests $150M in leading 'lab on a chip' medical diagnostics co.

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Houston-based health technology investment firm Hamershlag Private Capital Management Limited (HPCM) announced a $150.15 million venture investment in Patho Care LLC.

Patho Care is a “lab on a chip” medical diagnostics company known for its noninvasive point-of-care testing platforms, such as its Raman spectroscopy-based platform.

Its digital point-of-care testing devices are programmable, mobile, and reusable and can detect current or future respiratory bacterial or viral infections. The company says the technology is more cost-effective and provides results faster than traditional diagnostic methods.

“Patho Care LLC is a distinguished leader in healthcare diagnostics through the utilization of a novel approach with spectroscopy and this investment aligns with HPCM’s strategy of partnering with high-potential companies in dynamic industries,” L. Mychal Jefferson, Chairman of Hamershlag, said in a news release.

The transaction was structured as an acquisition and recapitalization using newly issued common stock and cash, which will work through a newly formed entity, PathoCare Holdings Inc. The deal will also facilitate the repayment of Patho Care LLC's existing financial obligations and settle Patho Care’s outstanding notes, helping ensure the company’s financial readiness, according to the release.

The investment will help Patho Care LLC improve operational efficiencies, broaden its service offerings and continue to innovate in the diagnostic testing space. The companies hope the collaboration will help “unlock new growth opportunities while maintaining the company’s legacy of excellence in an emerging technology,” according to a news release.

“Our commitment to delivering transformative value through innovative investments underscores our confidence in Patho Care’s vision and capabilities,” Jefferson added.