This Houston company is among the fastest-growing businesses in the state. Sean Pavone/Getty Images

A Houston-based company is among the 100 fastest growing businesses in the nation.

Homestead Brands, an e-commerce business comprised of the Lori Wall Beds and Organic Swings brands, grew 3,916 percent from 2017 to 2020, according to the newly released Inc. 5000 list. That makes the Humble-based business the eighth-fastest-growing private company in Texas and the 98th nationally.

"We are a team of A players determined to build the kind of company we all wish we could have worked at from the start of our careers: a place where everybody is valued, challenged, and comes to work with a sense of purpose," Homestead Brands says on its website.

A total of 90 Houston-area companies made the list. Other tech companies making the cut includes Onit, GoCo.io, Velentium, Softeq, Poetic, Techwave, and more.

Companies on the 2021 Inc. 5000 are ranked according to percentage growth in revenue from 2017 to 2020. To qualify, companies must have been founded and generating revenue by March 31, 2017. They also must be U.S.-based, privately held, for-profit, and independent. The minimum revenue threshold for 2017 is $100,000; the minimum for 2020 is $2 million. Among the 5,000 companies on the list, the average median three-year growth rate stood at 543 percent, and median revenue reached $11.1 million.

"The 2021 Inc. 5000 list feels like one of the most important rosters of companies ever compiled," Scott Omelianuk, editor-in-chief of Inc., says in an August 17 news release. "Building one of the fastest-growing companies in America in any year is a remarkable achievement. Building one in the crisis we've lived through is just plain amazing. This kind of accomplishment comes with hard work, smart pivots, great leadership, and the help of a whole lot of people."

San Antonio-based Texas Solar Integrated took the top spot statewide and ranked 11th nationally with a growth rate of 22,381 percent. The company installs commercial and residential solar energy systems.

"At Texas Solar, we treat our customers like family. We believe that successful relationships with partners and homeowners alike develop through transparency and the trust for doing things right the first time," the company says on its website.

The top-ranked company from the Austin area is Empowering a Billion Women, landing at No. 28. The company, which does business as EBW Worldwide, focuses on social, health, and economic empowerment of women. The company saw three-year revenue growth of 10,676 percent.

"Access to opportunity, education, and a support system for success is key to breaking the historical biases that have previously held women back from reaching their fullest social, health, and economic potential," says Linda Pringle Evans, dean of The EBW Business School for Women.

In Dallas-Fort Worth, Pomerenke Holdings is the top-ranked company on the Inc. 5000. Holding down the No. 73 spot, the automotive remarketer grew 5,164 percent from 2017 to 2020.

"Being ranked 73rd in a tough economic year for so many demonstrates the outstanding work and dedication of our team and partners," says Joey Pomerenke, founder and CEO of Pomerenke Holdings.

Following are other Texas companies that made the top 200 in the Inc. 5000, along with their three-year growth rates:

49. Residential real estate platform OJO Labs, Austin, 6,767 percent
77. Book club operator Literati, Austin, 4,898 percent
79. Tea-by-the-box purveyor Sips by, Austin, 4,754 percent
87. YouTube ad platform AdOutreach, Austin, 4,515 percent
120. Staffing agency Rayne Staffing, Houston, 3,390 percent
141. Dental services provider Endo1 Partners, Houston, 2,936 percent
165. Healthcare consulting firm ReMedi Health Solutions, Houston, 2,547 percent
169. Mortgage lender NXT Mortgage, Coppell, 2,496 percent
196. Software provider Noblesoft Technologies, Irving, 2,200 percent

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This article originally ran on CultureMap.

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European spacecraft developer expands to Houston with U.S. business, new lab

houston hq

European aerospace manufacturer The Exploration Company has established its first U.S. entity and named Space City as its headquarters.

The company announced earlier this month that it has launched TEC Federal to support U.S. government customers and agencies, and to scale The Exploration Company's engineering operations in the country.

Mark Kirasich serves as president of TEC Federal. Kirasich most recently served as the senior director of human spaceflight at Blue Origin after a nearly 40-year career at NASA.

The Exploration Company is developing the reusable Nyx space vehicle. Nyx is designed to take off from any heavy launcher in the world. It will then dock at space stations, retrieve up to 3,000 kilograms of cargo, splash down and return the cargo to Earth. The company aims to make Nyx fully reusable for up to 10 missions, making it a more affordable and sustainable option for aerospace missions.

The Exploration Company completed a successful drop test of the spacecraft in May in the Mojave Desert. The company says Nyx is slated to perform its first flight demonstration in 2028.

In addition to launching the Houston business, The Exploration Company also opened its new Rapid Innovation Lab near Houston's NASA Johnson Space Center on Space Park Drive.

The Exploration Company opened its Rapid Innovation Lab earlier this month. Photo via LinkedIn

The Rapid Innovation Lab features a full-scale mockup of the future Nyx crew capsule as well as ongoing development and testing of the Nyx cargo capsule, according to the company.

The Exploration Company says the new lab will allow its engineers, designers, and operators to prototype and test crew interfaces. It will also support partnerships with NASA personnel and astronauts.

“Houston gives us direct access to the people and expertise that have built and operated human spaceflight systems for decades. We’re excited to invest and expand around that— engineers, operators, and astronauts working together and moving quickly towards building a crew capsule.” Hélène Huby, founder and CEO of The Exploration Company, said in a blog post.

According to The Houston Chronicle, The Exploration Company has about 30 employees in the Houston area.

The company was founded in 2021 by Huby, a French rocket scientist, and has raised more than $350 million in venture capital. It operates out of Germany, France, Luxembourg, Spain and Italy, with offices in the U.S. and the United Arab Emirates. It is also developing a reusable, high-thrust rocket engine known as Storm.

UH lands $4M NIH grant to study early signs of autoimmune disease

NIH funding

The University of Houston recently received a $4 million National Institutes of Health grant to support a 10-year longitudinal study to identify the earliest biological markers of autoimmune disease.

Led by Chandra Mohan, the Hugh Roy and Lillie Cranz Cullen Endowed Professor of Biomedical Engineering, the study aims to examine what causes Systemic Autoimmune Rheumatic Diseases (SARDs) and to identify targets for future treatments. The study will be carried out in collaboration with Dr. Karen Costenbader at Harvard Medical School, Boston.

SARDs include conditions like rheumatoid arthritis, systemic lupus erythematosus, Sjögren’s syndrome and systemic sclerosis—all are considered chronic diseases currently without a cure. Autoimmune diseases affect over 30 million people globally, according to UH.

SARDs occur when the body’s immune system attacks healthy, non-threatening tissues and organs. According to UH, in these diseases, the body often attacks nuclear antigens, creating anti-nuclear autoantibodies, which can be early detection signs for SARDs in more than 50 percent of patients, Mohan says.

Researchers will study blood samples and environmental exposure over the 10 years to better understand anti-nuclear autoantibodies.

“Collectively, these studies will help identify the genetic, environmental and cellular factors that are operative at the two steps of SARD development, namely the emergence of anti-nuclear autoantibodies and disease onset,” Mohan said in a news release. “ More importantly, these studies will highlight functional molecular pathways and mechanisms that may be operative at each step."

Mohan predicts that looking at SARDs’ shared characteristics, rather than each disease individually, could help identify more treatment methods.

“Individual SARDs have been examined in silos without an attempt to discern shared underlying features at the molecular level,” he added in the release. “Current understanding of the initial (and likely shared) origins of SARDs is only rudimentary but urgently needed to develop means for prevention and treatment.”

Earlier this year, UH also received an $11 million NIH grant to conduct a first-of-its-kind study of early language development in children ages 18 to 24 months. Read more here.