Lindsey Rose King created a seasonal home goods box that shows consumers how to enjoy each item. Courtesy of Mostess

A few years ago, Lindsey Rose King offered to host her friend's engagement party, and she realized she had no clue where to start. There weren't any real resources out there for her to seek out.

King created Mostess, a seasonally curated home goods subscription box aiming to make it easier to host friends and family into their homes. The company was founded in January of 2017.

"I came up with the idea out of a need," says King, founder and lead curator, "it's hard to casually invite people into your house."

Almost two years later, King has managed to accomplish a lot of her goals, and Mostess has a great retention rate of subscribers with about a 30 percent growth each quarter, King says.

"We have a 5 percent churn rate, so 95 percent of customers have been customers since their first purchase," says King.

Mostess moves to disrupt the retail space by changing how consumers shop for home goods, accessories, and tabletop items. The box presents products in a different setting than consumers are used to seeing in a brick-and-mortar store by combining products from different brands and lines that may not be typically paired.

"Consumers are getting a product because we are referring it and picking it for them," King says. "We're choosing for the consumer, rather than them choosing themselves."

Growing business
In need of more space, the growing company recently moved into a warehouse in the Houston-area in a partnership with Alpha Graphics West Houston to launch its first local fulfillment center.

Currently, Mostess ships to 48 states, and next year, King says she wants to be able to ship to Alaska and Hawaii by July. Since the box has already got some buzz around it in Canada, King says she hope to be able to start her first international shipping there by 2020.

Mostess is in the wrapping up its busiest season; the company just released its winter box, which, along with the autumn box, King says subscribers usually purchase additional boxes for friends and family.

Looking forward to 2019, she's got exciting advancements for her subscribers.

In 2019, Mostess will begin offering slight customizations to each seasonal box and a special evergreen box. Customers will be able to purchase add-on items beginning with the spring box, such as extra candles or accessories in addition to what is offered. The Mostess evergreen boxes will have neutral and classic home accessories and hosting pieces. King says she wants these boxes to be a go-to gift idea or party-hosting asset for everything from a housewarming to an engagement party.

Starting from scratch
King first had the idea for Mostess toward the end of her 10-year stint living in Washington, D.C. Anticipating a move to Houston, King began to research local bloggers and small businesses to build a support system and platform for Mostess prior to the launch.

"In the small business world in Houston, there is the blogging community and there are actual small businesses," says King. "Both are very active and both very open to chatting about how to make business work between both of you."

King tells InnovationMap that Houston is an ideal city for an entrepreneur, offering a collaborative community of friendly, laid back, and hard-working small business owners.

King shares that she launched Mostess without any outside investment, using only her personal funds to get the product off the ground and relied on her friends and family as a test market. From there, she sought feedback from every single customer and potential customer, collected data, and tweaked details leading up to the launch.

"There was not a home goods subscription box on the market," says King, "I didn't have something to model after."

Elegant items shipped to your door

Paige Baker/Mostess

Mostess memberships begin at $120 per seasonal box.

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Rice University lands $18M to revolutionize lymphatic disease detection

fresh funding

An arm of the U.S. Department of Health and Human Services has awarded $18 million to scientists at Rice University for research that has the potential to revolutionize how lymphatic diseases are detected and help increase survivability.

The lymphatic system is the network of vessels all over the body that help eliminate waste, absorb fat and maintain fluid balance. Diseases in this system are often difficult to detect early due to the small size of the vessels and the invasiveness of biopsy testing. Though survival rates of lymph disease have skyrocketed in the United States over the last five years, it still claims around 200,000 people in the country annually.

Early detection of complex lymphatic anomalies (CLAs) and lymphedema is essential in increasing successful treatment rates. That’s where Rice University’s SynthX Center, directed by Han Xiao and Lei Li, an assistant professor of electrical and computer engineering, comes in.

Aided by researchers from Texas Children’s Hospital, Baylor College of Medicine, the University of Texas at Dallas and the University of Texas Southwestern Medical Center, the center is pioneering two technologies: the Visual Imaging System for Tracing and Analyzing Lymphatics with Photoacoustics (VISTA-LYMPH) and Digital Plasmonic Nanobubble Detection for Protein (DIAMOND-P).

Simply put, VISTA-LYMPH uses photoacoustic tomography (PAT), a combination of light and sound, to more accurately map the tiny vessels of the lymphatic system. The process is more effective than diagnostic tools that use only light or sound, independent of one another. The research award is through the Advanced Research Projects Agency for Health (ARPA-H) Lymphatic Imaging, Genomics and pHenotyping Technologies (LIGHT) program, part of the U.S. HHS, which saw the potential of VISTA-LYMPH in animal tests that produced finely detailed diagnostic maps.

“Thanks to ARPA-H’s award, we will build the most advanced PAT system to image the body’s lymphatic network with unprecedented resolution and speed, enabling earlier and more accurate diagnosis,” Li said in a news release.

Meanwhile, DIAMOND-P could replace the older, less exact immunoassay. It uses laser-heated vapors of plasmonic nanoparticles to detect viruses without having to separate or amplify, and at room temperature, greatly simplifying the process. This is an important part of greater diagnosis because even with VISTA-LYMPH’s greater imaging accuracy, many lymphatic diseases still do not appear. Detecting biological markers is still necessary.

According to Rice, the efforts will help address lymphatic disorders, including Gorham-Stout disease, kaposiform lymphangiomatosis and generalized lymphatic anomaly. They also could help manage conditions associated with lymphatic dysfunction, including cancer metastasis, cardiovascular disease and neurodegeneration.

“By validating VISTA-LYMPH and DIAMOND-P in both preclinical and clinical settings, the team aims to establish a comprehensive diagnostic pipeline for lymphatic diseases and potentially beyond,” Xiao added in the release.

The ARPA-H award funds the project for up to five years.

Houston doctor wins NIH grant to test virtual reality for ICU delirium

Virtual healing

Think of it like a reverse version of The Matrix. A person wakes up in a hospital bed and gets plugged into a virtual reality game world in order to heal.

While it may sound far-fetched, Dr. Hina Faisal, a Houston Methodist critical care specialist in the Department of Surgery, was recently awarded a $242,000 grant from the National Institute of Health to test the effects of VR games on patients coming out of major surgery in the intensive care unit (ICU).

The five-year study will focus on older patients using mental stimulation techniques to reduce incidences of delirium. The award comes courtesy of the National Institute on Aging K76 Paul B. Beeson Emerging Leaders Career Development Award in Aging.

“As the population of older adults continues to grow, the need for effective, scalable interventions to prevent postoperative complications like delirium is more important than ever,” Faisal said in a news release.

ICU delirium is a serious condition that can lead to major complications and even death. Roughly 87 percent of patients who undergo major surgery involving intubation will experience some form of delirium coming out of anesthesia. Causes can range from infection to drug reactions. While many cases are mild, prolonged ICU delirium may prevent a patient from following medical advice or even cause them to hurt themselves.

Using VR games to treat delirium is a rapidly emerging and exciting branch of medicine. Studies show that VR games can help promote mental activity, memory and cognitive function. However, the full benefits are currently unknown as studies have been hampered by small patient populations.

Faisal believes that half of all ICU delirium cases are preventable through VR treatment. Currently, a general lack of knowledge and resources has been holding back the advancement of the treatment.

Hopefully, the work of Faisal in one of the busiest medical cities in the world can alleviate that problem as she spends the next half-decade plugging patients into games to aid in their healing.