The train isn't official yet but now there's a builder in place. Photo courtesy of JR Central

The high-speed train between Houston and Dallas still needs an official sign-off before it happens, but a builder has been hired for when that day comes.

Texas Central, the developers of the train, have signed a $16 billion contract with Webuild, an engineering contractor company based in Milan.

Previously known as Salini Impregilo, Webuild is one of the largest civil engineering contractors in the world. They'll be working with The Lane Construction Corporation, a global leader in engineering and construction, to lead the civil construction team that will build the Texas rail line.

According to a release, Webuild is active in more than 50 countries on five continents, including Australia, Europe, Asia, and the Americas.

The company has built high-speed train projects in Europe, along with more complex transportation projects such as the expansion of the Panama Canal, the Grand Paris Express, and the Anacostia River and Northeast Boundary tunnels in Washington, DC.

They've worked in the U.S. since the 1980s but were able to expand their presence in 2016 by merging with The Lane Construction Corporation, based in Cheshire, Connecticut.

Webuild Group CEO Pietro Salini calls the commission an honor.

"Being part of such a challenging project as leader of the design and construction of the railway is a unique experience that we are extremely proud of," Salini says. "This is a wonderful opportunity to further focus our presence in the U.S., our biggest single market, together with Lane, the company building first class transport infrastructure for the country for the past 130 years."

According to the contract, Webuild will execute all the heavy construction for the project, designing and building 236 miles of the alignment, nearly half of it on viaduct and much of it elevated to reduce impact on neighbors and landowners.

Webuild will also build all maintenance and industrial buildings, train depots, and facilities.

The system Texas Central Railroad has proposed will replicate the Japanese Tokaido Shinkansen high-speed rail system, operated by the Central Japan Railway Company (JRC) which, in its 55+-year history has transported more than 10 billion passengers with zero operational passenger fatalities or accidents.

The 200-mph train will be a 90-minute ride between Houston and Dallas, with a midway stop in the Brazos Valley.

In May, Texas Central signed a $1.6 billion contract with Kiewit Infrastructure South Co. and affiliate Mass. Electric Construction Co. to install the train's core electrical systems.

The project has had pushback from some Texas politicians and landowners along the route, but the Biden administration is very pro rail, with a $2 trillion infrastructure package that includes modernizing public transit (commuter rail, buses, stations) and improving and expand the nation's passenger and freight rail network. He recently restored funding to a project that would connect San Francisco and Los Angeles.

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This article orignally ran on CultureMap.

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Texas space co. takes giant step toward lunar excavator deployment

Out of this world

Lunar exploration and development are currently hampered by the fact that the moon is largely devoid of necessary infrastructure, like spaceports. Such amenities need to be constructed remotely by autonomous vehicles, and making effective devices that can survive the harsh lunar surface long enough to complete construction projects is daunting.

Enter San Antonio-based Astroport Space Technologies. Founded in San Antonio in 2020, the company has become a major part of building plans beyond Earth, via its prototype excavator, and in early February, it completed an important field test of its new lunar excavator.

The new excavator is designed to function with California-based Astrolab's Flexible Logistics and Exploration (FLEX) rover, a highly modular vehicle that will perform a variety of functions on the surface of the moon.

In a recent demo, the Astroport prototype excavator successfully integrated with FLEX and proceeded to dig in a simulated lunar surface. The excavator collected an average of 207 lbs (94kg) of regolith (lunar surface dust) in just 3.5 minutes. It will need that speed to move the estimated 3,723 tons (3,378 tonnes) of regolith needed for a lunar spaceport.

After the successful test, both Astroport and Astrolab expressed confidence that the excavator was ready for deployment. "Leading with this successful excavator demo proves that our technology is no longer theoretical—it is operational," said Sam Ximenes, CEO of Astroport.

"This is the first of many implements in development that will turn Astrolab's FLEX rover into the 'Swiss Army Knife' of lunar construction. To meet the infrastructure needs of the emerging lunar economy, we must build the 'Port' before the 'Ship' arrives. By leveraging the FLEX platform, we are providing the Space Force, NASA, and commercial partners with a 'Shovel-Ready' construction capability to secure the lunar high ground."

"We are excited to provide the mobility backbone for Astroport's groundbreaking construction technology," said Jaret Matthews, CEO of Astrolab, in a release. "Astrolab is dedicated to establishing a viable lunar ecosystem. By combining our FLEX rover's versatility with Astroport's civil engineering expertise, we are delivering the essential capabilities required for a sustainable lunar economy."

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This article originally appeared on CultureMap.com.

Houston biotech co. raises $11M to advance ALS drug development

drug money

Houston-based clinical-stage biotechnology company Coya Therapeutics (NASDAQ: COYA) has raised $11.1 million in a private investment round.

India-based pharmaceuticals company Dr. Reddy’s Laboratories Inc. led the round with a $10 million investment, according to a news release. New York-based investment firm Greenlight Capital, Coya’s largest institutional shareholder, contributed $1.1 million.

The funding was raised through a definitive securities purchase agreement for the purchase and sale of more than 2.5 million shares of Coya's common stock in a private placement at $4.40 per share.

Coya reports that it plans to use the proceeds to scale up manufacturing of low-dose interleukin-2 (IL-2), which is a component of its COYA 302 and will support the commercial readiness of the drug. COYA 302 enhances anti-inflammatory T cell function and suppresses harmful immune activity for treatment of Amyotrophic Lateral Sclerosis (ALS), Frontotemporal Dementia (FTD), Parkinson’s disease and Alzheimer’s disease.

The company received FDA acceptance for its investigational new drug application for COYA 302 for treating ALS and FTD this summer. Its ALSTARS Phase 2 clinical trial for ALS treatment launched this fall in the U.S. and Canada and has begun enrolling and dosing patients. Coya CEO Arun Swaminathan said in a letter to investors that the company also plans to advance its clinical programs for the drug for FTD therapy in 2026.

Coya was founded in 2021. The company merged with Nicoya Health Inc. in 2020 and raised $10 million in its series A the same year. It closed its IPO in January 2023 for more than $15 million. Its therapeutics uses innovative work from Houston Methodist's Dr. Stanley H. Appel.

New accelerator for AI startups to launch at Houston's Ion this spring

The Collectiv Foundation and Rice University have established a sports, health and wellness startup accelerator at the Ion District’s Collectiv, a sports-focused venture capital platform.

The AI Native Dual-Use Sports, Health & Wellness Accelerator, scheduled to formally launch in March, will back early-stage startups developing AI for the sports, health and wellness markets. Accelerator participants will gain access to a host of opportunities with:

  • Mentors
  • Advisers
  • Pro sports teams and leagues
  • University athletics programs
  • Health care systems
  • Corporate partners
  • VC firms
  • Pilot projects
  • University-based entrepreneurship and business initiatives

Accelerator participants will focus on sports tech verticals inlcuding performance and health, fan experience and media platforms, data and analytics, and infrastructure.

“Houston is quickly becoming one of the most important innovation hubs at the intersection of sports, health, and AI,” Ashley DeWalt, co-founder and managing partner of The Collectiv and founder of The Collectiv Foundation, said in a news release.

“By launching this platform with Rice University in the Ion District,” he added, “we are building a category-defining acceleration engine that gives founders access to world-class research, global sports properties, hospital systems, and venture capital. This is about turning sports-validated technology into globally scalable companies at a moment when the world’s attention is converging on Houston ahead of the 2026 World Cup.”

The Collectiv accelerator will draw on expertise from organizations such as the Rice-Houston Methodist Center for Human Performance, Rice Brain Institute, Rice Gateway Project and the Texas Medical Center.

“The combination of Rice University’s research leadership, Houston’s unmatched health ecosystem, and The Collectiv’s operator-driven investment platform creates a powerful acceleration engine,” Blair Garrou, co-founder and managing partner of the Mercury Fund VC firm and a senior adviser for The Collectiv, added in the release.

Additional details on programming, partners and application timelines are expected to be announced in the coming weeks.