Nesh's digital assistant technology wants to make industry information more easily accessible for energy professionals. Photo courtesy of Thomas Miller/Breitling Energy

When Sidd Gupta's friend lost his job and struggled to find a new position after the major oil downturn in 2014, Gupta noticed a systemic problem within the industry.

"A company rejected him because he was unfamiliar with the software they used in their operations," Gupta explains. "In our industry, companies will judge a potential hire's technical capabilities based on which software they know how to use rather than how good they would be at the job."

While software requirements for oilfield jobs are common, it made Gupta consider how we can make complex data and knowledge more accessible.

Gupta saw something else brewing in the energy industry that also piqued his interest.

"There was entrepreneurship in the oil and gas space and an interest in data science during the oil downturn. We saw startups created in Austin then Houston. There was an infectious entrepreneurial energy at that time," he says.

Last year, he took the entrepreneurial leap, quit his job and founded Nesh, a smart assistant like Alexa or Siri, but specifically for oil and gas companies. Nesh sources information from public data, vendor sources, technical papers, journal articles, news feeds and more to give answers to complex, technical questions related to energy.

Nesh explained
Because this tool is meant for businesses and not personal use, the software must be trustworthy, Gupta says, and he asked himself what he needs to do to make an engineer or a CEO of an energy company believe Nesh's response.

The answer: transparency. With Nesh, users can see how the smart assistant came to its answer. The software shows the data and workflow behind the answer as part of the user interface.

And Nesh learns from its users too. If an unfamiliar question is posed to Nesh, users can add new training phrases to teach Nesh what to do next time the question is posed.

"We created Nesh as something super-simple to use," Gupta says. "There's no learning curve, no technical knowledge required, you just need to speak plain English."

Gupta, who was raised in India, came to the United States to pursue his master's degree in petroleum engineering at the University of Texas at Austin. After working in oil and gas for over a decade, he started Nesh last year with co-founder and CTO Seth Anderson.

Gearing up for the future
This year, Nesh is in the process of fundraising, and, with the new funds, he plans to expand his workforce, which is currently five employees (including Gupta himself) based in Houston. Due to its size, Nesh currently can run only one pilot program at a time. With more employees, Nesh will be able to scale up its pilot programs and run multiple pilots in parallel. The larger user pool for these pilots will give Gupta and his team better insights into Nesh and allow them to continue refining the tool.

Right now, Gupta wants to commercialize in those operations where Nesh is already running pilot programs. He says he hopes for Nesh to have both internal and external growth, with the next surge of hiring and an expanded user pool for the product.

He plans to make Nesh available as a commercial product in fall of this year with a target market of small to mid-sized oil and gas companies.

Gupta says Nesh is different from anything in the market.

"With enterprise software in general, it can be very hard to get a demo version of software without talking to a sales representative—something that people dislike," he says. "I want to bring the B2C aspect of trying a software to the B2B world."

The business model goal for Nesh is for potential clients to be able to test the software themselves, Gupta says, and then contact the company if they're interested.

"I want transparent pricing to be visible on our website," he says. "I want potential customers to be able to experience the demo just by giving their information."

As Gupta sees it, one of the main advantages to being in Houston is the important support networks as well as the potential customer base. He's grateful to local organizations such as Station Houston and Capital Factory for connecting him with many resources.

"I'm seeing a lot of innovation here in Houston," Gupta says. "There's a lot of oil and gas companies, so as we begin looking for potential customers, that's a very important advantage of being here."

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European spacecraft developer expands to Houston with U.S. business, new lab

houston hq

European aerospace manufacturer The Exploration Company has established its first U.S. entity and named Space City as its headquarters.

The company announced earlier this month that it has launched TEC Federal to support U.S. government customers and agencies, and to scale The Exploration Company's engineering operations in the country.

Mark Kirasich serves as president of TEC Federal. Kirasich most recently served as the senior director of human spaceflight at Blue Origin after a nearly 40-year career at NASA.

The Exploration Company is developing the reusable Nyx space vehicle. Nyx is designed to take off from any heavy launcher in the world. It will then dock at space stations, retrieve up to 3,000 kilograms of cargo, splash down and return the cargo to Earth. The company aims to make Nyx fully reusable for up to 10 missions, making it a more affordable and sustainable option for aerospace missions.

The Exploration Company completed a successful drop test of the spacecraft in May in the Mojave Desert. The company says Nyx is slated to perform its first flight demonstration in 2028.

In addition to launching the Houston business, The Exploration Company also opened its new Rapid Innovation Lab near Houston's NASA Johnson Space Center on Space Park Drive.

The Exploration Company opened its Rapid Innovation Lab earlier this month. Photo via LinkedIn

The Rapid Innovation Lab features a full-scale mockup of the future Nyx crew capsule as well as ongoing development and testing of the Nyx cargo capsule, according to the company.

The Exploration Company says the new lab will allow its engineers, designers, and operators to prototype and test crew interfaces. It will also support partnerships with NASA personnel and astronauts.

“Houston gives us direct access to the people and expertise that have built and operated human spaceflight systems for decades. We’re excited to invest and expand around that— engineers, operators, and astronauts working together and moving quickly towards building a crew capsule.” Hélène Huby, founder and CEO of The Exploration Company, said in a blog post.

According to The Houston Chronicle, The Exploration Company has about 30 employees in the Houston area.

The company was founded in 2021 by Huby, a French rocket scientist, and has raised more than $350 million in venture capital. It operates out of Germany, France, Luxembourg, Spain and Italy, with offices in the U.S. and the United Arab Emirates. It is also developing a reusable, high-thrust rocket engine known as Storm.

UH lands $4M NIH grant to study early signs of autoimmune disease

NIH funding

The University of Houston recently received a $4 million National Institutes of Health grant to support a 10-year longitudinal study to identify the earliest biological markers of autoimmune disease.

Led by Chandra Mohan, the Hugh Roy and Lillie Cranz Cullen Endowed Professor of Biomedical Engineering, the study aims to examine what causes Systemic Autoimmune Rheumatic Diseases (SARDs) and to identify targets for future treatments. The study will be carried out in collaboration with Dr. Karen Costenbader at Harvard Medical School, Boston.

SARDs include conditions like rheumatoid arthritis, systemic lupus erythematosus, Sjögren’s syndrome and systemic sclerosis—all are considered chronic diseases currently without a cure. Autoimmune diseases affect over 30 million people globally, according to UH.

SARDs occur when the body’s immune system attacks healthy, non-threatening tissues and organs. According to UH, in these diseases, the body often attacks nuclear antigens, creating anti-nuclear autoantibodies, which can be early detection signs for SARDs in more than 50 percent of patients, Mohan says.

Researchers will study blood samples and environmental exposure over the 10 years to better understand anti-nuclear autoantibodies.

“Collectively, these studies will help identify the genetic, environmental and cellular factors that are operative at the two steps of SARD development, namely the emergence of anti-nuclear autoantibodies and disease onset,” Mohan said in a news release. “ More importantly, these studies will highlight functional molecular pathways and mechanisms that may be operative at each step."

Mohan predicts that looking at SARDs’ shared characteristics, rather than each disease individually, could help identify more treatment methods.

“Individual SARDs have been examined in silos without an attempt to discern shared underlying features at the molecular level,” he added in the release. “Current understanding of the initial (and likely shared) origins of SARDs is only rudimentary but urgently needed to develop means for prevention and treatment.”

Earlier this year, UH also received an $11 million NIH grant to conduct a first-of-its-kind study of early language development in children ages 18 to 24 months. Read more here.