MindBar founder Hailey O’Neill wanted to make sure keeping up with mental health isn't a luxury. Photo courtesy of MindBar

Much easier than finding a therapist is finding laments at the cost and accessibility of mental health care. Group therapy is more affordable, but still a pricey and intimidating commitment. Text therapy like BetterHelp costs a lot more and often feels stilted. Now, a new Texas-based platform is paving the way for another option.

Although it may not replace the need for talk therapy entirely, MindBar, which launched in Austin in July, spreads the workload of coaches and therapists across many clients, keeps things online, and ultimately sets users up at their own pace. Like MasterClass for mental health, the app reduces the barrier to entry to just $14.99 per month.

The one-way service definitely can’t listen and identify a user’s thought patterns, or recommend personalized courses of action, but it can provide a wide series of useful primers to bring into talk therapy later, augment less frequent sessions, or just facilitate some preventative care and curiosity about the mind.

“MindBar has gained considerable traction since its launch in July, and our members have enjoyed the wide range of tools to cultivate a healthy mind,” writes MindBar founder Hailey O’Neill in an email interview. “We set out to represent the idea that mental health is a right, not a luxury, and the growth we’ve already seen within our app and its members is beginning to deliver on that ambition.”

Although MindBar is not therapy, it's also not YouTube. Classes take an experience or topic — stress, grief, and self-esteem to name a few — and break it down into video modules and worksheets. Each is organized and taught by one “teacher,” whose qualifications are clearly laid out in her biography from “years of coaching,” to therapy certifications and PhDs. Instead of browsing individual videos, users join each class; it’s just a click, but it feels distinct from mental health apps that encourage tackling everything at once.

Take the “Body Image” class as an example: It contains six modules of around 15 minutes, each paired with a multi-part “worksheet" of open-ended questions and text boxes for journaling on the platform. These are then wrapped up in a friendly little print out for those who’d prefer to write. If a user decided to moderate their own experience to simulate the commitment of traditional therapy (say 50 minutes biweekly), just taking this class could fill six to twelve weeks. Compare $30 for two months of MindBar to $450 for three therapy sessions.

Since MindBar exposes a user to the theory and methods of one particular professional, further avenues open up for extra or post-curricular work. Molly Seifert teaches “Body Image.” On Seifert’s MindBar biography page, there’s a link to her website and social media. Her credentials point out her 22-episode podcast, What She Gained, adding roughly 10 hours of free content to a user’s journey, should they follow her off the platform.

There is a button to book a session — something MindBar is working on finalizing — and on Seifert’s website, she offers a more involved “Body Confidence Program” that costs $897. Most users likely will not end up signing up for a teacher’s nearly-$1,000 group therapy track. However, the opportunity is there to follow this thread from a dip of the toes to a full-blown client-provider relationship.

A 2021 report by Sapien Labs’ Mental Health Million Project 2021 found that in the United States, 37 percent of respondents who did not seek help for clinical mental health problems did so because they lacked confidence in the mental health system. Nearly as many, 34 percent, did not know what kind of help to seek. More than a quarter preferred self-help. Imagine the shift if these respondents had a self-paced, minimal commitment platform that funneled them to professionals they learned to trust.

As of August 31, 2022, there are 26 classes on MindBar. Sign up at mind-bar.com.

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This article originally ran on CultureMap.

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New 'living pharmacy' biotech company launches out of Rice venture studio

fighting cancer

Rice University’s biotech venture studio RBL LLC has launched a new “living pharmacy” company, Duracyte, designed to make cancer treatment easier on patients.

Backed by an up to $45 million Advanced Research Projects Agency for Health (ARPA-H) award, Duracyte aims to commercialize implantable biohybrid pharmacy devices that are designed to produce therapeutic proteins inside the human body around the clock, replacing the need for regular injections and infusions for some cancer patients.

The company’s main platform is its Hybrid Advanced Molecular Manufacturing Regulator (HAMMR), a rechargeable, implantable device that can sense biological signals, monitor tumor environments and adjust therapeutic output in real time. HAMMR has wireless communication capabilities, which allow patients and clinicians to remotely monitor results through an app every five minutes and make changes to treatment plans without a hosptial visit. Additionally, the device can generate its own oxygen supply, which is key for the therapeutic cells’ survival.

“Biologic medicines such as monoclonal antibodies, cytokines and metabolic regulators already account for a significant share of modern therapeutics, but the way we deliver them today often requires frequent injections or infusions that can be demanding for patients and lead to inconsistent drug levels,” Daniel Anderson, MIT professor and co-founder of Duracyte, said in a news release. “Our vision is to enable a continuous, stable therapy by producing these medicines directly inside the body, which could improve treatment consistency, reduce side effects and ultimately transform how biologic therapies are delivered across many diseases.”

Duracyte’s first clinical trial is slated to begin by the end of 2026 and will focus on recurrent ovarian cancer. The Phase I study will build upon existing work on encapsulated cytokine pharmacy technology, and the company hopes that within a few years this treatment can reach clinical application.

The development of Duracyte is supported by ARPA-H's Targeted Hybrid Oncotherapeutic Regulation (THOR) project, which supports a multidisciplinary research consortium co-led by Omid Veiseh, a professor of bioengineering at Rice. The consortium also includes others at Rice, The University of Texas MD Anderson Cancer Center, Stanford University, Carnegie Mellon University, Northwestern University and the University of Houston, plus industry collaborators like Chicago-based CellTrans.

“What we are building is the culmination of years of progress in cell engineering, biomaterials and implantable device technology,” Veiseh added in the release. “By combining these advances with real-time sensing and adaptive drug delivery, we are working with the support of RBL to create a true ‘living pharmacy’ that can deliver continuous, precisely controlled biologic therapies and fundamentally change how these treatments reach patients.”

RBL launched in 2024 and is based out of Houston’s Texas Medical Center Helix Park. Duracyte is the third company launched by RBL, including Sentinel BioTherapeutics, a clinical-stage immunotherapy company developing localized cytokine therapies for solid tumors, and SteerBio, a regenerative medicine company targeting lymphedema.

“Duracyte exemplifies the kind of breakthrough that Houston’s ecosystem is built to produce,” Paul Wotton, managing partner of RBL LLC and co-founder of Duracyte, added in the release. “With world-class clinical infrastructure, exceptional engineering talent and initiatives like the Texas Biotech Task Force driving alignment across industry, investment and talent, this region is uniquely positioned to move the most ambitious ideas in medicine from concept to patient, faster than anywhere else.”

Houston energy hub opens new fundraising cohort to fuel startups

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EnergyTech Cypher has opened applications for its second Liftoff fundraising program.

Applications close May 20 for the 10-week virtual fundraising sprint. The program is geared toward energy and climatech founders preparing to raise their first institutional round. It will cover fundraising requisites, like pitch materials, term sheet negotiation and round closing, according to a release from EnergyTech Cypher.

The program kicks off June 1 and runs every Monday from 1-3 p.m. CST. It will conclude with an in-person capstone simulation in Houston on August 3, where founders will work to close a mock round.

Jason Ethier, EnergyTech Cypher founder and CEO, will lead the program with Payal Patel, an EnergyTech fellow and entrepreneur in residence.

The program is available through Cephyron, EnergyTech Cypher's new investor relationship management platform, built specifically for energy and climatech founders. Users must have a Cephyron Boost membership to participate in the Liftoff program.

The Cephyron IRM app recently went live and is available to founders at any point in their fundraising process, according to the news release. The platform aggregates investor data, tracks market signals and delivers curated weekly recommendations.

EnergyTech Cypher launched Liftoff last year. The inaugural cohort included 19 startups, including Houston-based AtmoSpark Technologies, The Woodlands-based Resollant and others. Each participant closed at least one fundraising deal, according to EnergyTech Cypher.

EnergyTech Cypher rebranded from EnergyTech Nexus earlier this year. It also launched its CoPilot accelerator in 2025. The inaugural group presented its first showcase during CERAWeek last month.

EnergyTech Cypher's annual Pilotathon Pilot Pitch and Showcase applications also opened this month. Find more information here.

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This article originally appeared on EnergyCaptialHTX.com.

Cancer diagnostics startup wins top prize at annual Rice competition​

winner, winners

Rice University student-founded companies took home a total of $115,000 in equity-free funding at the annual Liu Idea Lab for Innovation and Entrepreneurship's H. Albert Napier Rice Launch Challenge last week.

2025 Rice Innovation Fellow Alexandria Carter won the top prize and $50,000 for her startup Bionostic. The startup offers personalized diagnostics for cancer patients by using 3D culturing through its Advanced Tumor Landscape Analysis System (ATLAS) platform.

Carter is working toward her PhD in bioengineering in Professor Michael King's laboratory. She recently completed the Rice Innovation Fellows program and plans to commercialize ATLAS, according to a news release from Rice.

Actile Technologies, founded by another former Rice Innovation Fellow, Barclay Jumet, won second place and $25,000. The company is developing and commercializing textile-integrated technologies. InnovationMap first covered Jumet's wearable technology back in 2023.

Kairos took home the third-place prize and $15,000, plus the $2,000 audience choice award and the $5,000 undergraduate business award. Founded last year by Sanjana Kavula and Adhira Tippur, Kairos is an AI-powered patient intake platform built specifically for independent dental practices.

The NRLC features top startups founded by undergraduate, graduate and MBA students at Rice each year. The top three finishers were named among a group of five finalists earlier this year, which also included HAAST Autonomous and Project Kestrel.

HAAST is developing an unmanned aircraft for organ transport, while Kestrel uses machine learning to organize bird photographers’ photo collections.

Teams presented multiple five-minute pitches throughout the application process over Zoom and in-person before the five finalists presented at the NRLC Championships April 21 at the Rice Memorial Center. Each finalist walked away with an equity-free investment.


Other awards went to:

UnitCode

  • $5,000 MBA Venture Award

HAAST Autonomous

  • $2,500 Chan-Kang Family Prize for Bold Ambition
  • $1,000 Healthcare Innovations Prize

Telstar Networks

  • $2,500 Outstanding Undergraduate Startup Award

Multiplay

  • $1,500 Frank Liu Jr. Prize for Creative Innovation in Music, Fashion, & the Arts

Butterfly Books

  • $1,500 Social Impact Award

SOOZ

  • $1,000 Interdisciplinary Innovation Prize sponsored by OURI

Dooly

  • $1,000 Consumer Goods Prize

Project Kestrel

  • $1,000 AI Prize

Veloci Running won the NRLC last year for its naturally shaped running shoe. Founder and CEO Tyler Strothman recently told InnovationMap that the company has gone on to sell roughly 10,000 pairs of its flagship Ascent shoe, designed to relieve lower leg tightness and absorb impact. Read more here.