Know before you go: 2024 H-Town Roundup

Plan your week

Here's what you need to know about HTR this year. Photo courtesy

Next week, Houston Exponential's annual week of innovation and networking is taking place. Here are five things you need to know before you go.

1. New year, new name.

Houston Tech Rodeo, which originated in 2020, has been rebranded to H-Town Roundup, but the week of innovation and entrepreneurship still has the same goal of providing programming and events that connect and educate Houstonians.

On a recent episode of the Houston Innovators Podcast, Natara Branch, CEO of Houston Exponential, says the change is meant to make for a more inclusive experience for entrepreneurs of small businesses, something she's seen a need for since she took on her role last year.

"This year, we've had the better part of a year to think about what can be different and how can we serve the founder," she says.

Branch explains that some members of the Houston community confused the event for being associated with the Houston Livestock Show and Rodeo or for being only for true tech people. Branch says the wanted to open the door a little wider to entrepreneurs who are innovative without necessarily working in technology.

"That's not what we wanted — to exclude anyone," she says. "H-Town Roundup is going to allow us to be more inclusive."

2. It's completely free to attend.

Dozens of events are taking place around town, and all are free to Houston entrepreneurs, investors, and more. Simply register for anything you're able to attend.

For reference, a full, detailed agenda is available online too.

3. There are two featured events.

Need to make some priorities? This year, there are two featured events for HTR.

  • Tech and Tequila Talk powered by Blue People at 5 to 7:30 pm, on Tuesday, February 27, at the UH Tech Bridge Innovation Center.
  • CodeLaunch Houston at 4 to 9 pm, on Wednesday, February 28, at Bayou Music Center.

4. Introducing: The Founder Lounge.

For attendees with the founder pass, The Founder's Lounge at Esperson Building in downtown is open Monday through Thursday from 10 am to 3 pm next week.

The full agenda of talks planned at the lounge is online.

5. Find the activity zones.

HTR again is rotating venues. Here's where and when you can expect to find HTR activities.

  • Sunday (1 to 5 pm) - Esperson Building
  • Monday (8 am to 12:30 pm) - TMC Innovation
  • Monday (1:30 to 5 pm) - The Cannon Downtown
  • Tuesday (1 to 7:30 pm) - UH Tech Bridge
  • Wednesday (10 am to 1 pm) - Esperson Building
  • Wednesday (4 to 9 pm) - Bayou Music Center
  • Thursday ( 8 am to noon) - HCC Central Campus
  • Thursday (1 to 7 pm) - Greentown Labs
  • Friday (9 am to 3:30 pm) - the Ion
  • Saturday (10 am to 2 pm) - Esperson Building

Natara Branch, CEO of Houston Exponential, joins the Houston Innovators Podcast to discuss changes to the organization's spring summit. Photo courtesy of HX

HX revamps, rebrands annual innovation week to attract a wider range of entrepreneurs

HOUSTON INNOVATORS PODCAST EPISODE 215

For three years, Houston Exponential has hosted a week-long event showcasing and connecting Houston's tech and innovation community, but next year it might look a little different.

Houston Tech Rodeo, which originated in 2020, has been rebranded to H-Town Roundup, but the week of innovation and entrepreneurship still has the same goal of providing programming and events that connect and educate Houstonians. And, for the ease of transition, the organization is still conveniently referring to the event as HTR.

Natara Branch, CEO of Houston Exponential, says the change is meant to make for a more inclusive experience for entrepreneurs of small businesses, something she's seen a need for since she took on her role last year.

"This year, we've had the better part of a year to think about what can be different and how can we serve the founder," she says on the Houston Innovators Podcast.

Branch explains that some members of the Houston community confused the event for being associated with the Houston Livestock Show and Rodeo or for being only for true tech people. Branch says the wanted to open the door a little wider to entrepreneurs who are innovative without necessarily working in technology.

"That's not what we wanted — to exclude anyone," she says. "H-Town Roundup is going to allow us to be more inclusive."


CodeLaunch, a Plano-based accelerator that produces high-energy startup pitch events, is returning to HTR for 2024. Last year, the Houston winner, which was Energy360, went on to win overall, Branch says.

On the show, Branch says in general 2024 should be a better year for Houston's innovation ecosystem. In light of 2023's challenges and uncertainty, the year has not been a good one for anyone within the startup and tech value chain.

"We took a step back to take a step forward," Branch says, "and that's across the board — whether you're an investor, an organization, an entrepreneur — because there was so much uncertainty."

"Let's revisit the playbook," she adds. "We're facing a big game, and we can't use yesterday's tools to get there."

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CultureMap Emails are Awesome

Texas space co. takes giant step toward lunar excavator deployment

Out of this world

Lunar exploration and development are currently hampered by the fact that the moon is largely devoid of necessary infrastructure, like spaceports. Such amenities need to be constructed remotely by autonomous vehicles, and making effective devices that can survive the harsh lunar surface long enough to complete construction projects is daunting.

Enter San Antonio-based Astroport Space Technologies. Founded in San Antonio in 2020, the company has become a major part of building plans beyond Earth, via its prototype excavator, and in early February, it completed an important field test of its new lunar excavator.

The new excavator is designed to function with California-based Astrolab's Flexible Logistics and Exploration (FLEX) rover, a highly modular vehicle that will perform a variety of functions on the surface of the moon.

In a recent demo, the Astroport prototype excavator successfully integrated with FLEX and proceeded to dig in a simulated lunar surface. The excavator collected an average of 207 lbs (94kg) of regolith (lunar surface dust) in just 3.5 minutes. It will need that speed to move the estimated 3,723 tons (3,378 tonnes) of regolith needed for a lunar spaceport.

After the successful test, both Astroport and Astrolab expressed confidence that the excavator was ready for deployment. "Leading with this successful excavator demo proves that our technology is no longer theoretical—it is operational," said Sam Ximenes, CEO of Astroport.

"This is the first of many implements in development that will turn Astrolab's FLEX rover into the 'Swiss Army Knife' of lunar construction. To meet the infrastructure needs of the emerging lunar economy, we must build the 'Port' before the 'Ship' arrives. By leveraging the FLEX platform, we are providing the Space Force, NASA, and commercial partners with a 'Shovel-Ready' construction capability to secure the lunar high ground."

"We are excited to provide the mobility backbone for Astroport's groundbreaking construction technology," said Jaret Matthews, CEO of Astrolab, in a release. "Astrolab is dedicated to establishing a viable lunar ecosystem. By combining our FLEX rover's versatility with Astroport's civil engineering expertise, we are delivering the essential capabilities required for a sustainable lunar economy."

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This article originally appeared on CultureMap.com.

Houston biotech co. raises $11M to advance ALS drug development

drug money

Houston-based clinical-stage biotechnology company Coya Therapeutics (NASDAQ: COYA) has raised $11.1 million in a private investment round.

India-based pharmaceuticals company Dr. Reddy’s Laboratories Inc. led the round with a $10 million investment, according to a news release. New York-based investment firm Greenlight Capital, Coya’s largest institutional shareholder, contributed $1.1 million.

The funding was raised through a definitive securities purchase agreement for the purchase and sale of more than 2.5 million shares of Coya's common stock in a private placement at $4.40 per share.

Coya reports that it plans to use the proceeds to scale up manufacturing of low-dose interleukin-2 (IL-2), which is a component of its COYA 302 and will support the commercial readiness of the drug. COYA 302 enhances anti-inflammatory T cell function and suppresses harmful immune activity for treatment of Amyotrophic Lateral Sclerosis (ALS), Frontotemporal Dementia (FTD), Parkinson’s disease and Alzheimer’s disease.

The company received FDA acceptance for its investigational new drug application for COYA 302 for treating ALS and FTD this summer. Its ALSTARS Phase 2 clinical trial for ALS treatment launched this fall in the U.S. and Canada and has begun enrolling and dosing patients. Coya CEO Arun Swaminathan said in a letter to investors that the company also plans to advance its clinical programs for the drug for FTD therapy in 2026.

Coya was founded in 2021. The company merged with Nicoya Health Inc. in 2020 and raised $10 million in its series A the same year. It closed its IPO in January 2023 for more than $15 million. Its therapeutics uses innovative work from Houston Methodist's Dr. Stanley H. Appel.

New accelerator for AI startups to launch at Houston's Ion this spring

The Collectiv Foundation and Rice University have established a sports, health and wellness startup accelerator at the Ion District’s Collectiv, a sports-focused venture capital platform.

The AI Native Dual-Use Sports, Health & Wellness Accelerator, scheduled to formally launch in March, will back early-stage startups developing AI for the sports, health and wellness markets. Accelerator participants will gain access to a host of opportunities with:

  • Mentors
  • Advisers
  • Pro sports teams and leagues
  • University athletics programs
  • Health care systems
  • Corporate partners
  • VC firms
  • Pilot projects
  • University-based entrepreneurship and business initiatives

Accelerator participants will focus on sports tech verticals inlcuding performance and health, fan experience and media platforms, data and analytics, and infrastructure.

“Houston is quickly becoming one of the most important innovation hubs at the intersection of sports, health, and AI,” Ashley DeWalt, co-founder and managing partner of The Collectiv and founder of The Collectiv Foundation, said in a news release.

“By launching this platform with Rice University in the Ion District,” he added, “we are building a category-defining acceleration engine that gives founders access to world-class research, global sports properties, hospital systems, and venture capital. This is about turning sports-validated technology into globally scalable companies at a moment when the world’s attention is converging on Houston ahead of the 2026 World Cup.”

The Collectiv accelerator will draw on expertise from organizations such as the Rice-Houston Methodist Center for Human Performance, Rice Brain Institute, Rice Gateway Project and the Texas Medical Center.

“The combination of Rice University’s research leadership, Houston’s unmatched health ecosystem, and The Collectiv’s operator-driven investment platform creates a powerful acceleration engine,” Blair Garrou, co-founder and managing partner of the Mercury Fund VC firm and a senior adviser for The Collectiv, added in the release.

Additional details on programming, partners and application timelines are expected to be announced in the coming weeks.